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      • 아미노 실란을 이용한 고 기능성 착색 콘택트렌즈 소재 개발

        박혜인(Hye-In Park),신수미(Su-Mi Shin),성아영(A-Young Sung) 케이뷰티인학회 2022 케이뷰티인학회지 Vol.2 No.2

        최근 다양한 색을 가진 선글라스와 콘택트렌즈를 사용하고 있으며, 아미노기와 실린기는 pH를 조절하고 용해, 안정, 반응성을 개선해 다양한 분야에서 사용하고 있다. 고분자 중합을 위해 노란색을 띠고 아미노 실린을 갖는 N-[3-(Trimethoxysilyl)propyl] ethylenediamine(NPED)을 첨가제로 사용하여 기본적인 하이드로겔 소재, 실리콘 하이드로겔 소재와 함께 각각 공중합 하였고, 제조된 안 의료용 렌즈의 함수율, 굴절률, 산소투과율, 광투과율 등의 기본적인 물성을 측정하였다. PNED를 첨가한 하이드로겔 소재와 실리콘 하이드로겔 소재에서 붉은색과 노란색의 착색 렌즈가 각각 제조되었고, 자외선 차단이 우수한 것으로 나타났다. 또한, NPED의 첨가비율이 증가함에 따라 각각의 소재에서 굴절률 및 함수율은 서로 다른 특성을 나타내었으며, 산소투과율은 실리콘 하이드로겔 소재에서 향상된 것으로 나타났다. 따라서 제조된 렌즈는 착색 기능 및 다양한 기능성을 가진 미용 콘택트렌즈의 재료로 사용할 수 있을 것으로 판단된다. Recently, sunglasses and contact lenses of various colors have been used, and amino groups and silyl groups have been used in various fields by adjusting pH and improving dissolution, stability, and reactivity. For polymer polymerization, N-[3-(Trimethoxysilyl)propyl]ethylenediamine (NPED) with amino silyl groups was copolymerized together with a basic hydrogel material and a silicon hydrogel material, and basic physical properties such as water content, refractive index, oxygen permeability, and light transmittance were measured. Red and yellow colored lenses were manufactured in hydrogel materials to which NPED was added and silicon hydrogel materials, respectively, and UV protection was excellent. In addition, as the addition ratio of NPED increased, the refractive index and water content of each material showed different characteristics, and the oxygen permeability was improved in the silicon hydrogel material. Therefore, it is determined that the manufactured lens may be used as a material for beauty contact lenses having a coloring function and various functions.

      • KCI등재

        내시경을 이용한 코경유눈물주머니코안연결술의 수술 시간 관련 예측 인자

        박혜인(Hye In Park),이강원(Kang Won Lee),강성모(Sung Mo Kang) 대한안과학회 2017 대한안과학회지 Vol.58 No.7

        목적: 내시경을 이용한 코경유눈물주머니코안연결술 시행에 있어서 수술 시간에 영향을 미치는 예측 인자에 대해 분석하고자 한다. 대상과 방법: 2009년 4월부터 2014년 6월까지 5년에 걸쳐 내시경을 이용한 코경유눈물주머니코안연결술을 받은 66명 66안을 대상으로 수술 시간을 측정하고, 환자의 나이, 성별, 질환의 분류(염증성 vs. 비염증성), 전신 질환(당뇨, 고혈압, 항응고제 사용 여부, 부비동염 과거력), 술 전 안와 컴퓨터 단층 사진을 통해 측정한 상악동의 전두돌기 두께 등 각 요인들과 수술 시간의 관련성, 수술 시간과 증상 재발 혹은 재수술 여부의 상관관계에 대하여 후향적 분석을 시행하였다. 비정상적 비강 구조를 가진 경우, 다른 수술을 동반 시행했거나 코경유눈물주머니코안연결술을 양측에 동시에 시행한 경우는 제외하였다. 결과: 평균 수술 시간은 49.95분이었다. 또한 코눈물길 막힘의 원인을 분류했을 때 비염증성보다 염증성의 경우(p=0.047)에서 술 전안와 컴퓨터 단층 촬영을 통해 측정한 상악동의 전두돌기 두께가 얇을수록 평균 수술 시간이 더 짧았다(p=0.001). 또한 연구 기간인 5년을 크게 세 시기로 나누어 분석했을 때 최근 마지막 시기의 수술 시간이 가장 짧은 것으로 나타났다(p=0.001). 또한 수술 시간이 길수록 증상이 재발했거나 재수술을 한 빈도가 높은 것으로 나타났다(p=0.012). 결론: 술자의 숙련도와 코눈물관막힘의 원인을 분석하고 술 전 안와 컴퓨터 단층 사진을 통한 상악동의 전두돌기 두께 측정을 통해 내시경을 통한 코경유눈물주머니코안연결술의 소요 시간을 예측 가능하며 이는 수술 예후와도 관련성이 있다. <대한안과학회지 2017;58(7):757-762 > Purpose: To determine the prognostic factors associated with surgical time of endonasal dacryocystorhinostomy (DCR). Methods: From April 2009 to June 2014, 66 eyes of 66 patients who underwent endonasal DCR for 5-year periods were retrospectively evaluated with regard to surgical time and several other factors. The factors were patient factors (age, sex), category of diagnosis (inflammation and non-inflammation), and systemic factors (diabetes mellitus [DM], hypertension [HTN], anticoagulant agents, sinusitis history). We divided the study period into three subperiods and compared their surgical time. The anatomical factor of thickness of the maxillary frontal process was evaluated by computed tomography (CT), as was the existence of symptom recurrence after surgery and reoperation according to surgical time. A total of 66 cases (right: 31, left: 35) were included. Any case with concurrent surgery, abnormal structure of the nasal cavity, or bilateral DCR was excluded. Results: Average surgical time was 49.95 minutes. Surgical time of endonasal DCR was short in inflammatory cases (p = 0.047), in the third surgical period (p = 0.001), and was correlated with thickness of the maxillary frontal process (p = 0.001). In addition, surgical time correlated with the existence of symptom recurrence after surgery and reoperation (p = 0.012). Conclusions: It is considered that surgeon skill affects surgical time, and the thickness of the maxillary frontal process by CT will aid in the prediction of surgical time and success rate of endonasal DCR. J Korean Ophthalmol Soc 2017;58(7):757-762

      • KCI등재

        조선총독부청사 철거문제를 통해 본 한국건축계의 의식변화에 관한 연구

        박혜인(Park Hye-In),김현섭(Kim Hyon-Sob) 대한건축학회 2010 대한건축학회논문집 Vol.26 No.10

        The purpose of this research is to study on the change of consciousness in Korean architectural circles through the demolition matter of the Chosun Government General Building. The function of the building has changed several times throughout the Korean modern history owing to its context related to history, location, and architectural & constructional style. In particular, the demolition of this building became a turning point for Korean architectural circles to raise their consciousness. That is to say, this event made them rethink about an interpretation of historical buildings and also about placeness of them in the historical urban context. In addition, they pursued independence of architecture from external factors like the political power, and tried to reach to a contact point between architecture and the public. However, the change of their consciousness still left limitations to be considered, such as that they were not able to subjectively interpret Korean modernity and that no practical movements followed up to complete the demolition debates. Despite these limitations, this paper argues that the debates concerning the building's demolition were meaningful in itself, particularly because they illustrated social meanings of architecture and raised Korean architectural circles' consciousness in history.

      • KCI등재

        가정의례의 변화와 21 세기의 지향 모색

        박혜인(Hye In Park) 한국아동가족복지학회 2001 한국가족복지학 Vol.6 No.1

        The first purpose of this study is to identify the characteristics of the family ritual transition in order to comprehend the structural and symbolic process of Korean family life. And the second purpose is to explore the directions toward the new century in the rapidly industrializing Korea. It may be summarized as follows: I discovered the pervasive themes of family ritual transition : westernization, commercialism, socialization, feudalism, cultural lag and anomie. But contemporary rituals repoduce the forms and contents of traditional ones as family rituals. They continue to provide a place where participants reproduce the ideology of patriarchal family group. Therefore foreign elements exist in parallel with pre-existing traditional elements. Therefore, in contemporary rituals the family must restore its cultural meaning as a space for the interaction among family members, kins and neighbors. So culture movement to accede creative family ritual tradition by NGO is recommended.

      • KCI등재

        지역사회 청소년에서 체중과 자아존중감, 우울 및 불안 간의 관계

        박혜인(Hye-In Park),권선영(Seon-Young Kwon),정철호(Chul-Ho Jung) 대한생물치료정신의학회 2010 생물치료정신의학 Vol.16 No.1

        Objectives:This study was designed to evaluate the association among the degree of obesity, body satisfaction, self-esteem, depression and anxiety in adolescents, and to examine the mediation effect of self-esteem on body satisfaction and psychological distress such as depression and anxiety. We also sought to investigate the gender differences between depression and anxiety according to the degree of obesity. Methods:The information on weight, height, age and gender was collected from 342 high school students. The self-reporting questionnaires composed of Visual analog scale of body satisfaction, Rosenberg Self-Esteem Scale(RSES), Korean version of Beck Depression Inventory(BDI), and State-Trait Anxiety Inventory(STAI) were completed by the subjects and the results were analyzed. Results:112(63.3%) of the 177 male students were normal, 25(14.1%) were overweight, and 40(22.6%) were obese. 140(84.8%) of the 165 female students were normal, 14(8.5%) were overweight, and 11(6.7%) were obese. Body Mass Index(BMI) of the male students was negatively correlated with body satisfaction and RSES and was positively correlated with BDI and STAI. BMI of the female students had significantly negative correlation only with body satisfaction. Body satisfaction and RSES were negatively correlated with BDI and STAI among both male and female students. As a result of path analysis, self-esteem mediated the association between body satisfaction and psychological distress such as depression and anxiety. As the three weight groups were compared with the mean score of each scale, there were significant differences among the male groups in body satisfaction, RSES, BDI and STAI. However, there was significant difference only in body satisfaction among the three female groups. Conclusion:These findings showed that the more obese the adolescents were, the lower their body satisfaction was. They also suggested that its effect on psychological distress such as depression and anxiety was mediated by self-esteem. Therefore, it suggests that psychological approach for improving self-esteem and correcting the distorted cognition for body image is helpful for the obese adolescents.

      • KCI등재후보

        눈물주머니에 발생한 면역글로불린 G4 연관 염증성 낭종 1예

        박혜인(Hye In Park),이강원(Kang Won Lee),주영채(Young Chae Chu),강성모(Sung Mo Kang) 대한검안학회 2017 Annals of optometry and contact lens Vol.16 No.3

        Purpose: The aim of this study is to report a case of IgG4-related inflammatory cyst of lacrimal sac. Case summary: A 40-year-old female complained of left upper eyelid swelling with redness of duration 18 months. Initial her visual acuity was 20/20 (OD), 20/20 (OS). Swelling with an erythematous lesion was found on the left upper eyelid and an erythematous palpable mass was present at the left medial caruncle. The exophthalmometry exam revealed proptosis of 2.0 mm on the left eye. Computed tomography (CT) depicted a 1.0 × 1.6 × 2.4 cm sized cystic mass on the lacrimal sac extending to the left medial canthus. The patient underwent endoscopic biopsy and dacryocystorhinostomy with silicone tube intubation, and during the surgery, a whitish yellow mucoid discharge drained from the lacrimal sac, which was dense lymphoplasmacytic infiltrates with H&E staining, and many IgG- and IgG4-positive plasma cells were observed in high power fields during anti-IgG and anti-IgG4 antibody examinations. After procedure, orbital mass decreased on CT. After obtaining the pathologic result, serum IgG4 was normal at 68.3 mg/dL (normal range 3.9-86.4 mg/dL) and serum IgG was also normal as 1,285 mg/dL (normal range 870-1,700 mg/dL). The erythrocyte sedimentation rate was 8 mm/hour. Conclusion: We obtained the pathologic results of lymphoplasmacytic infiltrates and many IgG- and IgG4-positive plasma cells in lacrimal sac, and this case showed IgG4-related disease involved a lacrimal sac and created an inflammatory cyst in the sac initially in Republic of Korea.

      • KCI등재

        난소의 경화성 간질종양 1 예

        박혜인 ( Park Hye In ),김종수 ( Kim Jong Su ),최승도 ( Choe Seung Do ),선우재근 ( Seon U Jae Geun ),배동한 ( Bae Dong Han ),김영화 ( Kim Yeong Hwa ),김윤정 ( Kim Yun Jeong ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.2

        Sclerosing stromal tumor is a rare benign neoplasm of ovarian stromal origin, distinct from the thecoma-fibroma group and steroid (lipid) cell tumors clinically, pathologically, and radiographically. Unlike the thecoma-fibroma group of ovarian stromal tumors, which tend to occur in the fith and sixth decades, the sclerosing stromal tumor predominantly affects young women with a mean age of 28 years. Microscopic examination reveals a heterogenous picture that is characterized by sclerosis, prominant vascularity and a discorganized admixture of fibroblasts and vacuolated cells. We could not demonstrate unequivocal hormonal activity in this case, although suggestive evidence for it has been reported in the literature in the form of clinical, histologic, electron microscopic and immunohistochemical findings. We recently experienced a case of sclerosing stromal tumor of the ovary in 20 year-old virgin woman. We report a case here with a brief review of the literature.

      • KCI등재

        국내 시판 호상 요구르트의 품질 특성 분석

        원주인(Ju In Won),이지현(Ji Hyun Lee),박혜인(Hye In Park),조여울(Yeo Ul Cho),최인덕(In Duck Choi),이석기(Seuk Ki Lee),박혜영(Hye Young Park),박지영(Ji Young Park),오세관(Sea Kwan Oh),한상익(Sang Ik Han),최혜선(Hye Sun Choi) 한국식품영양과학회 2018 한국식품영양과학회지 Vol.47 No.11

        요구르트는 전유 또는 탈지유를 유산균으로 발효시켜 신맛과 향미를 강화한 대표적인 유 발효식품으로 최근 유고형분 함량과 유산균 수가 많은 호상 요구르트의 수요가 증가하고 있다. 본 연구는 국내 시판되고 있는 호상 타입의 요구르트 20종을 수집하여 제품의 일반적 특성을 조사하였고, pH, 가용성 고형분, 총산, 점도, 호기성・혐기성 유산균 수를 측정하여 기초자료로 제공하고자 하였다. 원유(100%), 탈지분유(70%), 유청 분말(65%), 유크림(40%)이 주원료로 사용되고 다양한 프로바이오틱 유산균주가 단일 또는 복합균주로 첨가되며, modified starch(60%) 및 sugar(45%)가 주된 첨가당류로 사용되었고, amid pectin(45%)은 물성개선재로 가장 높은 빈도로 사용되었다. 20종의 호상 요구르트 제품 간의 품질 특성을 분석한 결과 pH는 4.18~4.60, 총산도는 0.55~1.30%, 가용성 고형분은 7.10~18.13%, 점도는 183.7~901.0 cP로 나타났으며, 호기성 균과 혐기성 균은 106~108 이상으로 식품공전에서 규정하고 있는 일정 수준인 것으로 나타났다. 제품 간에 차이가 나타나는 이유는 첨가물과 점도조절에 따른 점도 증진제 및 스타터의 차이에 기인하는 것으로 보인다. 본 결과는 다양한 기능성 소재 및 소비트렌드를 반영한 요구르트 개발 품질지표 설정의 주요한 기초자료로 사용될 수 있을 것으로 판단된다. Yogurt is produced by the fermentation of milk using bacteria known as “yogurt cultures”. Most of these bacteria are probiotics, such as Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus rhamnosus, Streptococcus thermophilus, and Bifidobacterium. The domestic fermented milk market is increasing, and approximately 30 companies are producing yogurt. This study assessed the quality characteristics of domestic commercial semisolid type yogurt. A total of 20 types of commercial yogurts were sampled and their physicochemicial properties, including pH, sugar content, acidity, viscosity, and microbial characteristics of lactic acid bacteria, were measured. Commercial semisolid type yogurt showed a pH of 4.18∼4.60, sugar content of 7.10∼18.13%, total acid content of 0.55∼1.30%, and viscosity of 183.7∼901.0 cP. In terms of the microbial populations, the lactic acid bacteria counts were 6.47∼11.50 log CFU/mL and anaerobic lactic acid bacteria counts were 7.24∼10.98 log CFU/mL. The quality characteristics differed depending on the constituents of the sample and the microorganisms used. These results are expected to be useful for identifying new trends in the domestic fermented milk industry.

      • KCI등재SCOPUS

        국내 시판 액상요구르트의 품질특성

        이지현,박혜영,원주인,박혜인,최인덕,이석기,박지영,조동화,전용희,오세관,한상익,최혜선,Lee, Ji Hyun,Park, Hye Young,Won, Ju In,Park, Hye In,Choi, In Duck,Lee, Seuk Ki,Park, Ji Young,Joe, Dong Hwa,Jeon, Yong Hee,Oh, Sea Kwan,Han, Sang Ik,Ch 한국식품저장유통학회 2017 한국식품저장유통학회지 Vol.24 No.6

        Yogurt is produced by fermentation of milk using bacteria known as "yogurt cultures". Most of these bacteria are probiotics such as Lactobacillus delbrueckii subsp. bulgaricus, Lb. rhamnosus, Streptococcus thermophilus, and Bifidobacterium. The domestic fermented milk market is increasing, and about 30 companies are producing yogurt. The purpose of this study was to analyze the quality characteristics of domestic commercial liquid yogurt. Total 30types of commercial yogurts were sampled and their physicochemicial properties, including pH, sugar content, acidity, viscosity, and microbial characteristics of lactic acid bacteria counts, were measured. Commercial liquid type yogurt showed a pH of 4.5, sugar content of 7.4-21.2%, total acid content of 0.4-0.9%, and viscosity of 0.1-250 cP. In terms of microbial populations, lactic acid bacteria counts were 7.2-11.3 log CFU/mL and anaerobic lactic acid bacteria counts were 8.0-11.5 log CFU/mL. The quality characteristics differed depending on the constituents of the sample and the microorganisms used. These results are related to the quality characteristics of yogurts and are useful for identifying new trends in the domestic fermented milk industry. 요구르트는 유산균을 이용하여 제조한 대표적인 유발효식품이다. 국내 유통되고 있는 요구르트는 약 30개의 업체에서 생산되고 있으며, 최근 당 저감화 정책 실시로 저당제품이 출시되고 있다. 본 연구는 국내 시판되고 있는 액상타입의 요구르트를 수집하여 제품의 일반적인 특성을 조사하였고, pH, 산도, 당도, 점도, 호기성 혐기성 유산균수를 측정하여 기초자료로 사용하고자 하였다. 탈지분유(97%) 및 원유(57%)가 주된 원료로 높은 빈도로 사용되고 있으며, 발효스타터는 요구르트에 100% 이용되고 있으며 주로 수입균주가 이용되고 있다. 당은 sucrose, oligosaccharide, xylitol이 첨가되었고, 그 외 구연산, vitamin C, gum류 등이 요구르트의 기능성과 물성 등을 개선하고자 하는 부원료로 사용되고 있는 것을 확인하였다. 30종의 요구르트의 품질특성을 분석한 결과 pH는 3.6-4.6, 당도는 7.4-21.2%, 총산도는 0.4-0.9%, 호기성 유산균수 7.2-11.3 log CFU/mL, 혐기성 유산균수는 8.0-11.5 log CFU/mL로 분석되었다. 본 연구에서 도출된 시판 액상타입 요구르트의 품질분석 결과는 다양한 소재를 접목한 요구르트 개발의 품질규격설정의 기초자료로 유용 할 것으로 사료된다.

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