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조혜진 ( Hye Jin Cho ),이금정 ( Keum Jung Lee ),차선화 ( Sun Hwa Cha ),성석주 ( Seok Ju Seong ),박종택 ( Chong Taik Park ),이기헌 ( Ki Heon Lee ),전이경 ( Yi Kyeong Chun ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.4
Since Sampson first described the development of ovarian carcinoma in endometriosis in 1925, numerous case reports have documented the development of malignancies arising from foci of endometriosis. Clear cell carcinoma arising from endometriosis is very
실험연구 : 생쥐(Mice)에서 하지무부하가 심혈관계 기능에 미치는 영향
이영복 ( Young Bok Lee ),박종택 ( Jong Taek Park ),임현교 ( Hyun Kyo Lim ),최재찬 ( Jae Chan Choi ),김순열 ( Soon Yul Kim ),조준현 ( Jun Hyun Cho ),이광호 ( Kwang Ho Lee ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.53 No.2
Background: Orthostatic intolerance is a debilitating problem that can occur after prolonged bed-rest, exposure to microgravity, and in the elderly. This study examined the integrated cardiovascular response to baroreceptor activation in a hind-limb unweighing (HLU) mouse model of microgravity to test the hypothesis that both the pressor and contractility response are attenuated in HLU mice. Methods: C57BL/6 mice (25-30 g body wt, 8-10 wk old) were exposed to HLU for 2 weeks. A bilateral carotid artery occlusion and open-loop baroreceptor stimulus was performed to measure the myocardial contractile responses using a left ventricular micromanometer-conductance catheter in the mice. In isolated myocytes simultaneous sarcomere shortening and calcium transient were measured in response to increasing concentrations of the β-agonist isoproterenol. Results: In the controls, bilateral carotid artery occlusion increased the heart rate and mean arterial pressure. These responses were markedly attenuated in the HLU mice. A bilateral carotid artery occlusion also increased the slope of the end-systolic pressure volume relationship (Ees) by 70 ± 11% and the slope was markedly attenuated to 10 ± 8% in the HLU mice. Isoproterenol increased the sarcomere shortening in both control and HLU mice in a dose-dependent manner. However the contractile response to isoproterenol was significantly attenuated in the HLU mice than the controls. Conclusions: Both the pressor and myocardial contractile responses appear to be impaired in a mouse model of microgravity. (Korean J Anesthesiol 2007; 53: 222~8)
조영진(Young Jin Cho),지홍근(Hong Keun Ji),김선재(Sun Jae Kim),임규영(Kyu Young Lim),이동규(Dong Kyu Lee),최경원(Gyeong Won Choi),박종택(Jong Taek Park),문병선(Byung Sun Moon),고재모(Jae Mo Goh),박남규(Nam Kyu Park) 한국화재소방학회 2020 한국화재소방학회논문지 Vol.34 No.2
2013년 11월 한국의 농촌 주택에서 발생한 여성 신체의 지속적인 연소 사례가 제시된다. 여성의 신체 중 무릎에서목 부분까지는 거의 완전하게 소각되었고 머리, 팔, 무릎 아래의 다리 및 발은 거의 연소되지 않은 상태로 발견되었다. 외부 점화원으로는 성냥에 의한 불씨가 가장 유력했다. 거실 바닥에서 발견된 할머니만 주로 연소되었으며, 주택안에 있는 다른 사물들은 검갈색의 기름이 묻은 것처럼 또는 기름으로 코팅된 것처럼 보였으며 사실상 거의 연소되지 않았다. 변사자의 타지 않은 의류 및 양말에서 인화성 물질이 검출되지 않았으며, 근육 조직에서 약독물 성분 또한 확인되지 않았다. 말초 혈액의 혈중일산화탄소-헤모글로빈 농도는 11%, 안방수의 에틸알콜농도는 0.010% 미만이었다. 부검 결과 탄화가 고도로 진행되어 사망원인을 단정하기 어려웠다. In November 2013, a case of sustained combustion of a female body was encountered in a Korean farming village. Thebody was almost completely incinerated from the neck to the knees, and other parts of the body, such as the head, arms,lower legs, and feet, were slightly damaged. The most likely external ignition source was the flame from a matchstick. Theelderly woman was found incinerated on the floor of the living room, while other objects in the house were largelyundamaged except for having a brown oily or greasy coating. Flammable substances were not detected from the woman’sintact pieces of clothing and socks, and her muscular tissues did not contain toxic chemicals. The concentration ofcarboxyhemoglobin in her peripheral blood was 11% and that of ethyl alcohol in her aqueous humor was below 0.010%. An autopsy failed to determine the exact cause of death because of excessive charring.
복강경보조질자궁절제술과 복강경전자궁절제술의 수술결과 비교
박현 ( Hyun Park ),최민철 ( Min Chul Choi ),윤보성 ( Bo Sung Yoon ),성석주 ( Seok Ju Seong ),조연경 ( Yeon Kyung Cho ),신중식 ( Joong Sik Shin ),전혜선 ( Hye Sun Jun ),심정연 ( Jeong Yun Shim ),김인현 ( In Hyun Kim ),박종택 ( Cho 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.7
목적: 복강경보조질자궁절제술 (LAVH)과 복강경전자궁절제술 (TLH)의 수술 결과를 비교하고자 하였다. 방법: 병원기록을 바탕으로 2006년 9월부터 2007년 8월까지 복강경자궁절제술을 받았고 병리소견이 자궁근종 혹은 샘근육증인 경우만을 대상으로 하여 LAVH를 받은 93명과 TLH를 받은 142명을 선정하였다. 수술방법에 따라서 환자의 인구학적 특징과 수술결과를 비교하였다. 여러 변수들 사이의 관계를 알아보고자 다중회귀분석을 실시하였다. 결과: 두 군 간에 나이 및 체질량지수, 수술력, 병리소견은 차이가 없었다. 단변량 분석에서 LAVH의 수술시간 (129.0±34.5분, 123.6±40.8분)과 실혈량 (385.5±296.1 mL, 294.7±285.4 mL)이 증가하였다 (P<0.050). 검체무게는 LAVH에서 무거운 경향이 있었으며 (378.7±211.7 g, 316.9±170.1 g, P=0.060), 입원기간 (5.63±1.61일, 5.71±1.61일)과 부작용 발생률 (10.8%, 14.0%)은 차이가 없었다 (LAVH, TLH, P>0.050). 다변량 분석에서 실혈량은 수술시간 및 검체무게과 관련이 있었으며 (P=0.000), 수술방법과는 관련이 적었다 (P=0.213). 결론: TLH에 비하여 LAVH가 시행된 경우에는 자궁이 무겁고 수술시간이 길며 실혈량이 많은 경향이 있었다. 다변량 분석을 통하여 복강경자궁절제술에서 실혈량은 수술방법과는 관련이 없으며 검체무게 및 수술시간과 비례함을 알 수 있었다. Objective: To compare the surgical outcomes between laparoscopy-assisted vaginal hysterectomy (LAVH) and total laparoscopic hysterectomy (TLH). Methods: The data were collected retrospectively from hospital records. Between September 2006 and August 2007, Patients undergone with LAVH (93 cases) and TLH (142 cases) with pathologic reports of leiomyoma or adenomyosis were enrolled. The characteristics and surgical results were compared according to the operation type. The correlations among the variables were analyzed with multiple linear regression. Results: Between two groups, the characteristics of patients were similar such as age, body mass index, surgical history, and pathologic findings. In the univariate analysis, the differences of operation duration and blood loss between LAVH (129.0±34.5 min, 385.5±296.1 mL) and TLH (123.6±40.8 min, 294.7±285.4 mL) were significant (P<0.050). Specimen weight was slightly heavier in LAVH (378.7±211.7 g vs. 316.9±170.1 g, P=0.060), Admission duration (5.63±1.61 day vs. 5.71±1.61 day) and the incidence of complications (10.8% vs. 14.0%) were indifferent to the groups (LAVH vs. TLH, P>0.050). In multivariate analysis, blood loss was correlated with operation duration and specimen weight (P=0.000) but not with operation type (P=0.213). Conclusions: LAVH tends to be selected in larger uteri and results in more blood loss and longer operation duration. Operation type (LAVH or TLH) does not affect blood loss which is related with operation duration and uterine weight.