SMI군과 Non-SMI군의 사망원인 비교분석 : 일 장기요양기설 입소자를 대상으로

문수진,김경훈,송지영,백종우,Moon, Su Jin,Kim, Kyoung Hoon,Song, Ji Young,Paik, Jong-Woo 대한생물정신의학회 2009 생물정신의학 Vol.16 No.3

Objectives : Schizophrenia and other psychiatric disorder are associated with an increased risk of premature death. For decades, there have been reports of shorter life expectancy among those with severe mental illness. The purpose of this study was to compare the risk of mortality among institutionalized population, treated for severe mental illness to control group who did not have severe mental illness. Methods : The medical records and the death certificates of 2,029 institutionalized population who had died from 1985 to 2003 in Kkottongnae were investigated. Results : The mean age of the death of severe mental illness(SMI) group(51.4${\pm}$15.3 years old) was lower than that of non-severe mental illness(non-SMI) group(65.0${\pm}$19.3 years old) and it was statistically significant(p<0.0001). The most causes of death among the SMI group were respiratory diseases(23.3%), infectious disease (13.0%) and digestive disease(12.3%). Also, we found that the death due to injuries of the SMI group(8.9%) were three times higher than that of non-SMI group(2.5%). The most causes of death among the non-SMI group were respiratory disease(26.3%), circulatory disease(26.2%) and neoplasm(10.8%). Conclusion : The SMI group demonstrated higher mortality rates compared with the rate in the non-SMI group. The finding suggests that careful intervention is needed not only for menal health but also physical health in long-term facilities.

Immunoglobulin G4 연관 질환

문수진 ( Su Jin Moon ),민준기 ( Jun Ki Min ) 대한류마티스학회 2015 대한류마티스학회지 Vol.22 No.4

Immunoglobulin G4-related disease (IgG4-RD) is an emerging immune-mediated fibro-inflammatory disorder which can involve any organ. The main characteristics of IgG4-RD are increased serum IgG4 concentration, abundant IgG4+ plasma cells in affected tissues, and painless swollen organs often without general symptoms. Typical pathology features of IgG4-RD are lymphoplasmacytic infiltration, dense storiform fibrosis, and obliterative pheblitis. The pathogenesis of IgG4-RD remains elusive, but involvement of excess production of type 2 T helper cells, regulatory T-cell cytokines, and B-cell activating factor in the development of IgG4-RD has been suggested. Diagnosis of IgG4-RD can be made on the basis of serological, imaging, particularly histopathological findings. Glucocorticoid is the first-line therapy for patients with multiple organ dysfunction and clinical symptoms. Drugs such as azathioprine, mycophenolate mofetil, methotrexate, and cyclophosphamide can be used as steroid-sparing agents. Rituximab is reported to be an effective therapy for treatment of IgG4-RD, even without concomitant glucocorticoid therapy. This review summarizes current concepts on pathophysiology, clinical manifestations, and treatment of IgG4-RD. (J Rheum Dis 2015;22:213-222)

한국인 조기 류마티스관절염 환자에서의 2010 ACR/EULAR 분류 기준의 유용성 및 한계

문수진 ( Su Jin Moon ),이창훈 ( Chang Hoon Lee ),김윤성 ( Yun Sung Kim ),박윤정 ( Yun Jung Park ),강귀영 ( Kwi Young Kang ),곽승기 ( Seung Ki Kwok ),김해림 ( Hae Rim Kim ),주지현 ( Ji Hyeon Ju ),김현숙 ( Hyun Sook Kim ),서영일 ( Y 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.6

The 2010 New American College of Rheumatology/ European League Against Rheumatism (ACR/EULAR) criteria for rheumatoid arthritis (RA) was raised to identify patients with early RA and replaced the 1987 ACR classification criteria. The aims of this study are to assess the availability of new classification criteria and to evaluate its Methods. A total of 408 patients with newly diagnosed RA were included from 13 secondary or tertiary hospitals in South Korea. The symptom duration was less than 12 months before the diagnosis of RA. RA was defined as either 1987 ACR classification criteria or new 2010 ACR/EULAR criteria. We compared the full details of both classification criteria. Results. The mean symptom duration was 5.1 months. The majority (76.2%) of the patients were female. Two hundred and seventy three patients (66.9%) fulfilled both of the 2010 and 1987 classification criteria. Forty-seven (14.7%) of the 320 patients fulfilling the 1987 criteria did not fulfill the new classification criteria. On the other hand, eighty-eight (24.4%) of the 361 patients fulfilling the 2010 ACR/EULAR classification criteria did not fulfill the 1987 ACR criteria. Thirty-six (55.4%) of the 65 patient with seronegative RA failed to meet the 2010 classification criteria. In case of seropositive RA (n=343), 85 additional patients (24.8%) could be diagnosed as RA using new classification criteria. The new 2010 ACR/EULAR classification criteria enable physicians to diagnose more patients with early RA via the help of serology. However, the sensitivity for the diagnosis of seronegative RA is projected to decrease.

영상 정합 및 통계학적 패턴 분류를 이용한 호흡률 측정에 관한 연구

문수진(Su-jin Moon),이의철(Eui Chul Lee) 인문사회과학기술융합학회 2018 예술인문사회융합멀티미디어논문지 Vol.8 No.10

영상을 이용한 생체 신호 측정 기술이 발전하고 있으며, 특히 생명 유지를 위한 호흡 신호 측정기술 연구가 지속적으로 진행되고 있다. 기존 기술은 사람의 몸에서 방출하는 열을 측정하는 열화상 카메라를 통하여 호흡 신호를 측정하였다. 또한, 실시간으로 사람의 흉부 움직임을 분석하여 호흡률을 측정하는 연구도 진행되었다. 하지만, 적외선 열화상 영상을 이용하여 영상 처리를 하는 것은 외부 환경 요인으로 인해 호흡 기관의 탐색이 어려울 수 있으며, 이에 따라 호흡률 측정의 정확도가 떨어지는 문제들이 발생했다. 본 연구에서는 호흡 기관의 영역 탐색을 강화하기 위해 가시광 및 적외선 열화상 카메라를 이용하여 영상을 취득하였다. 그리고 두 영상을 기반으로 얼굴 인식, 영상 정합 등의 과정을 통해 호흡 기관 영역의 특징을 추출한다. 추출한 특징 값을 통계학적 분류 방법 중 하나인 k-최근접 이웃 분류기를 통해 호흡 신호의 패턴을 분류한다. 분류한 패턴의 특성에 따라 호흡률을 계산하며, 측정한 호흡률의 성능을 확인하기 위해 실제 호흡률과 비교 과정을 통해 분석함으로써, 호흡률 측정의 가능성을 확인하였다. Biomedical signal measurement technology using images has been developed, and researches on respiration signal measurement technology for maintaining life have been continuously carried out. The existing technology measured respiratory signals through a thermal imaging camera that measures heat emitted from a person s body. In addition, research was conducted to measure respiration rate by analyzing human chest movement in real time. However, the image processing using the infrared thermal image may be difficult to detect the respiratory organ due to the external environmental factors (temperature change, noise, etc.), and thus the accuracy of the measurement of the respiration rate is low.In this study, the images were acquired using visible light and infrared thermal camera to enhance the area of the respiratory tract. Then, based on the two images, features of the respiratory tract region are extracted through processes such as face recognition and image matching. The pattern of the respiratory signal is classified through the k-nearest neighbor classifier, which is one of the statistical classification methods. The respiration rate was calculated according to the characteristics of the classified patterns and the possibility of breathing rate measurement was verified by analyzing the measured respiration rate with the actual respiration rate.

정신과 전공의의 수련 기간 중 비 약물 치료법 경험

문수진(Su Jin Moon),박준헌(Jun Heon Park),김태(Tae Kim),송지영(Ji Young Song),반건호(Geon Ho Bahn) 대한사회정신의학회 2009 사회정신의학 Vol.14 No.1

목 적: 현재 한국의 정신과 사 년 차를 대상으로 정신과 전공의 수련 과정에서 이루어지는 약물 치료 이외의 치료 방법들에 대한 현황을 파악하고 분석해 봄으로써 앞으로의 다양한 치료 방법들에 대한 정신과 전공의 수련 교육의 내용과 수준, 교육 방식을 설정하고 문제점 및 개선 방안을 모색해 볼 수 있는 계기를 마련코자 한다. 연구대상 및 방법: 두 달 동안 전국 72개 수련병원에서 근무 중인 전공의 사년 차 126명을 대상으로 설문 검사를 실시하였고 총 63명(50%)이 응답하였다. 설문지의 보기에는 총 39가지의 치료법을 제시하였다. 결 과: 현 전공의 사 년 차가 수련 기간 동안 경험한 치료 술기의 수는 최소 1개에서 최대 17개로, 평균 6.9개의 치료술기를 경험하 였다. 지역별 차이(수도권 지역과 비수도권 지역)와 전공의의 치료 술기의 다양성은 유의한 차이를 보이지 않았다. 병원 내 전문의의 수와 연 차별 전공의의 수는 치료 다양성은 양의 상관관계를 맺고 있었다. 전공의 들은 현재 병원 내에서 시행하고 있지는 않으나 관심이 있는 분야로 최면(45%), EMDR(26.7%), 예술치료(21.7%)를 꼽았다. 결 론: 전공의가 경험하는 치료 내용의 양적 및 질적 차이가 줄어들 수 있도록 본 학회는 물론 각 분과 학회의 배려가 필요할 것이다. Objective:The aim of this study was to survey fourth year psychiatric residents' experience about the application of non-pharmacological therapies during their residency training in Korea. This survey may help trainer to determine how psychiatric trainee think about their level of education, content of education, methods of education, and current problems in psychiatric residency training, as well as to reform the non-pharmacological psychiatric therapies. Methods:A total of 63 subjects completed the questionnaires we sent. 39 types of therapy were included in the questionnaire. Results:The results of our survey showed that the total number of therapies that residents were exposed to during their four years of training ranged from 1 to 17 (6.9±3.3). The regional disparity, the nation’s metropolitan area vs non-metropolitan area, had non-significant effect on the diversity of non-pharmacological psychiatric interventions. The number of faculty members and the number of residents were positively correlated with the diversity of nonpharmacological psychiatric therapies. The results of our survey also showed that many residents were interested in other types of non-pharmacological psychiatric interventions that they have not been exposed to, such as hypnosis (45%), EMDR (26.7%), and art therapy (21.7%). Conclusion:It would be necessary to reduce differences of both quantity and quality of therapies experienced among psychiatric residents for improving in residency training system.

청소년용 정신화 프로그램의 학생정신건강 증진효과 평가

문수진(Su Jin Moon),오소영(So Young Oh),이원혜(Won Hye Lee),홍민하(Min Ha Hong),민정원(Jung Won Min),김봉석(Bong Seog Kim),황준원(Jun Won Hwang),우이혁(Ieehyok Woo),반건호(Geon Ho Bahn) 대한소아청소년정신의학회 2012 소아청소년정신의학 Vol.23 No.3

Objectives:Understanding the emotions, thoughts, feelings and behaviors of others, as well as oneself, is part of the mentalizing function. We developed a new school-based community model for mental health, called the Mentalization Improvement Program for Adolescent-Community Model (MIPAdo-CM), based on the concept of mentalization. Methods:The MIPAdo-CM was composed of 12 sessions and was applied to 403 students in the 2nd grade of a middle school. Every session was conducted after the regular school hours for 6 weeks. After 6 weeks, we compared the endpoint changes of Adolescent Mental Problem Questionnaire-Revised (AMPQ-R), Emotional Empathy Test (EET), Peer Aggression Scale (PAS), Peer Bullying Scale (PBS), School Adjustment Scale (SAS), Test Anxiety Inventory (TAI) and Visual Analogue Scale between the subject and the control group. Results:There was no significant difference between two groups in AMPQ-R, EET, PAS, PBS, SAS, and TAI. On the Visual Analoge Scale, however, students in the trial classes reported more increase in understanding and respect for both others and themselves. Conclusion:The efficacy of MIPAdo-CM was subjective improvement of understanding and respect for both others and themselves, erence between two groups in AMPQ-R, Empathy test, To prove objective usefulness of this program, further studies with more structured design will be needed.

수혈 전 예방적 투약의 필요성에 대한 근거기반간호 사례

문수진(Moon, Su Jin),박정옥(Park, Jeong Ok),서은정(Seo, Eun Jeoung),최진오(Choi, Jin Oh),김경희(Kim, Kyeong Hee) 한국근거기반간호학회 2020 근거와 간호 Vol.8 No.1

감작된 환자에서 rituximab 유도 요법을 이용한 3차 신장 이식 1례

문수진 ( Su Jin Moon ),김수현 ( Su Hyun Kim ),윤혜은 ( Hye Eun Yoon ),김용균 ( Yong Kyun Kim ),최범순 ( Bum Soon Choi ),양철우 ( Chul Woo Yang ),김용수 ( Yong Soo Kim ),방병기 ( Byung Kee Bang ) 대한신장학회 2007 Kidney Research and Clinical Practice Vol.26 No.5

경화증 동물 모델에서 Apigenin의 치료 효과

문수진 ( Su Jin Moon ),민준기 ( Jun Ki Min ) 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.5

정신분열병 환자에서의 병식과 사회적 단서 인식능력간의 관계 연구

문수진 ( Su Jin Moon ),박정수 ( Jeong Soo Park ),이원혜 ( Won Hye Lee ),김종우 ( Jong Woo Kim ),백종우 ( Jong Woo Paik ),송지영 ( Ji Young Song ) 한국정신병리진단분류학회 2010 精神病理學 Vol.19 No.1

Objective: In the patients with schizophrenic disorder, lack of insight might have a direct effect on the prognosis and which lead to an overall decline in his social cue perception. And, the social cognition abilities in the schizophrenic patient, especially the perception of emotions, are proposed as important variant factors in his/her handicap in social function. However, there is currently a lack of studies that directly explore the relationship between insight and social cue perception, and no relationships between the two have been established. This study seeks to focus on the relationship between the schizophrenic patient`s abilities in the perception of emotion and his/her insight. Methods: In this study, a total of 29 subjects, all of whom were patients that had been diagnosed with schizophrenia, were evaluated with the Korean version of the SUMD-K(The Scale to Assessment Unawareness of Mental Disorder: Korean Version), a method recognized in its validity and reliability to measure the subjects` insight. To measure the social cue perception of the subjects, the study utilized an evaluation method called the Korean-Social Cue Recognition Test-Revised(K-SCRT-R), which uses 8 stages: positive-middle arousal, positive-high arousal, negative-middle arousal, and negative-high arousal to assess the subjects. Results: There seemed to be no correlation between the SUMD-K score and age, years of education, IQ, and the negative symptom score in PANSS. However, the SUMD-K score had a moderate positive correlation with the positive symptom score in PANSS(r=.419, p<.05), and a significant negative correlation with the GAF score(r=-.568, p<.01). The score in negative-high arousal, a part of K-SCRT-R, had a significant negative correlation with the negative symptom score of PANSS(r=-.518, p<.01). Particularly, the SUMD-K score showed a significant negative correlation with the negative-high arousal stage(r=-.501, p<.01). Conclusion: Although for schizophrenic patients, the more severe the positive symptoms are, the more they suffer from lack of insight, there was no direct correlation between the positive symptom and the social cue perception ability. However, out of the social cue perception abilities, the decrease in perception ability in the negative high-arousal stage had a high correlation to the lack of insight, and the negative symptoms also had a high correlation with the perception ability in the negative-high arousal stage. Therefore, even though the severity of positive symptoms is related directly to the lack of insight, it did not show a direct relation to the decline in social cue perception ability. Rather, considering that the severity of the negative symptom, which has no direct relation to the lack of insight, has a strong relation to the decline in social cue perception abilities in the negative-high arousal stage, the schizophrenic patient`s social cue perception ability, especially his ability in the negative-high arousal stage, is likely to be due to the structural changes in the brain that result in negative symptoms and decline of insight.