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유방암 진단 후 보이는 우울증상과 기질 및 성격특성에 대한 연구
김신희 ( Shin Hee Kim ),한오수 ( Oh Soo Han ),엄태문 ( Tae Moon Erm ),김진용 ( Jin Young Kim ),안세현 ( Sei Hyun Ahn ) 한국정신병리진단분류학회 2005 精神病理學 Vol.14 No.1
Objectives: First, the objective of the present study was to investigate the differences of temperament and character traits between depression group(n=27) and non-depression group(n=29) in Breast Cancer patients. Second, it was to explore the effect of those factors on depression in breast cancer patients. Methods: Of the 115 subjects, 56 individuals were completed the 17-item Hamilton Depression Rating Scale(HDRS-17) with clinician and Korean version of Temperament and Character Inventory (TCI). Results: depression group showed significantly higher ``Harm avoidance``, and lower Self-directedness` score as compared to non-depression group. The stepwise linear regression analysis showed ``HA1(worry and pessimism)`` was the only significant predicting variable for depression. Conclusion: These data suggest that temperaments and characters should be considered in studies investigating depression from acute stressful events.
김태호 ( Tae Ho Kim ),문석우 ( Seok Woo Moon ) 한국정신병리진단분류학회 2011 精神病理學 Vol.20 No.1
Maternal psychopathology has been associated with child psychological development. When mother is suffered depression in peripartum period there are excessive activity and growth delays in the fetus as well as prematurity, low birthweight, disorganized sleep and less responsiveness to stimulation in the neonate. Infants of depressed mothers have difficult temperament, attentional, emotional and behavioral problems during childhood and adolescence as well as adulthood. Potential mediating variables are low prenatal maternal dopamine & serotonin levels and elevated cortisol & norepinephrine levels. The associated intrauterine artery resistance may limit blood flow, oxygen and nutrients to the fetus. Some studies suggest the heritability of developmental problems for the children of depressed mothers, including ADHD and antisocial behavior.
김시경 ( Sie Kyeong Kim ) 한국정신병리진단분류학회 2006 精神病理學 Vol.15 No.1
Objectives: This study aimed to examine the characteristics of married women complaining of depressive symptoms by assessing their psychopathology, life event stress, stress perception and coping skills, and to analyze the effects of those characteristics on outcomes after 12 months. The results are expected to provide basic data for testing the diagnostic validity of housewife depression. Method: The subjects were 52 housewives who visited the psychiatric outpatient clinic of Chungbuk National University Hospital with depressive symptoms during March to August 2005. After a psychiatric interview, the subjects filled a Korean version of symptom checklist-90-revision, life experience survey and stress perception questionnaire and ways of coping skills I checklist, and they were compared with a control group of 60 healthy women. After 12 months, the changes of subjective depressive feelings were evaluated through face-to-face or telephone interviews. Results: Depression group had higher academic qualifications than before, and while the cases of conversions or somatizations decreased but emotional symptoms such as anxiety and depression increased. Major stressors had been diversified from family problems to social problems. Although active coping skills increased, passive coping skills did not decreased. Psychopathological factors and negative life events were closely related to subjective depressive feelings measured after 12 months. Conclusions: With the development of society, stress factors and the psychopathology of housewives with depression are being modernized. However, the stress perception and coping skills look to follow the characteristics of traditional society. The progress of housewife depression was significantly affected mainly by early psychopathology and negative life event.
이윤나 ( Yunna Lee ),전진숙 ( Jin Sook Cheon ),최영식 ( Young Sik Choi ),오병훈 ( Byoung Hoon Oh ) 한국정신병리진단분류학회 2015 精神病理學 Vol.23 No.1
연구목적 : 자가면역 갑상선장애 환자에서 삶의 질(quality of life, 이하 QoL) 저하 여부와 이들의 QoL에 관계되는 변인을 규명하기 위함이다. 연구방법 : 자가면역 갑상선장애 환자 41명과 건강한 대조군 40명을 대상으로 구조적 면담과 한국판 세계보건기구 삶의 질 간편형 척도(WHOQOL-BREF)를 사용한 QoL 평가 및 한국판 Hamilton 우울증 평가척도(K-HDRS)를 사용한 우울증 평가를 시행하였다. 연구결과 : 1) 자가면역 갑상선장애 환자군은 대조군 보다 유의하게 전체 QoL 점수, 일반적 건강, 영역1(신체적 건강 영역), 영역 2(심리적 영역), 영역 3(사회적 관계 영역) 및 영역 4(환경적 영역) 점수가 낮았다(각각 p<0.001). 2) 전반적 QoL은 K-HDRS 점수 및 경제수준, 일반적 건강은 K-HDRS 점수와 유의한 역상관관계가 있었다(각각 p<0.01). 전체 QoL 점수는 교육수준과 유의한 순상관관계, K-HDRS 점수 및 경제수준과 유의한 역상관관계가 있었다 (각각 p<0.01). 신체적 건강 영역은 K-HDRS 점수(p<0.01)와 유의한 역상관관계, antimicrosomal 항체(p<0.05)와 유의한 순상관관계가 있었다. 심리적 영역은 TSH와 유의한 순상관관계(p<0.05), K-HDRS 점수(p<0.01) 및 T3(p<0.05)와 유의한 역상관관계가 있었다. 사회적 관계 영역은 K-HDRS 점수와 유의한 역상관관계(p<0.01)가 있었다. 환경적 영역은 교육수준과 유의한 순상관관계, 경제수준과 유의한 역상관관계가 있었다(각각 p<0.01).3) 회귀분석에서 antimicrosomal 항체는 전체 QoL 점수에 역의 영향(β=-0.002)을 미쳤으며, 전반적 QoL(β=0.037), 일반적 건강(β=0.023), 신체적 건강 영역(β=0.003), 심리적 영역(β=0.006), 사회적 관계 영역(β=0.013) 및 환경적 영역(β=0.004)에 순의 영향을 미쳤다(각각 p<0.01). 결론 : 본 연구의 결과는 자가면역 갑상선장애 환자에서 삶의 질 저하에 가장 중요한 결정인자는 갑상선항체 (antimicrosomal 항체)임을 시사하였다. Objectives : The aims of this study were to know whether quality of life (QoL) was lowered in patients with autoimmune thyroid disorders, and to identify influencing factors on their QoL. Methods : Demographic and clinical data were obtained by structured interviews for healthy controls (N=40) and patients with autoimmune thyroid disorders (N=41). The measurements of QoL and depression were also performed using Korean Version of WHOQOL-BREF and Korean Version of Hamilton Deression Rating Scale. Results : 1) The total QoL scores, general health, domain 1 (physical health domain), domain 2 (psychological domain), domain 3 (social relationship domain) and domain 4 (environmental domain) were significantly lower in patients with autoimmune thyroid disorder than those of healthy controls (p<0.001, respectively). 2) Overall QoL had negative correlation with K-HDRS and economic status, and general health had negative correlation with K-HDRS (p<0.01, respectively). Total QoL scores had positive correlation with education, and had negative correlation with K-HDRS and economic status (p<0.01, respectively). Physical health domain had negative correlation with K-HDRS (p<0.01), and had positive correlation with antimicrosomal antibodies (p<0.05). Psychological domain had positive correlation with TSH (p<0.05), and had negative correlation with K-HDRS (p<0.01) and T3 (p<0.05). Social relationship domain had negative correlation with K-HDRS (p<0.01). Environmental domain had positive correlation with education, and had negative correlation with economic status (p<0.01, respectively). 3) According to regression analysis, antimicrosomal antibodies influenced negatively on the total QoL scores (β=-0.002), and positively on the overall QoL (β=0.037), general health (β=0.023), physical health domain (β=0.003), psychological domain (β=0.006), social relationship domain(β=0.013) and environmental domain (β=0.004)(p<0.01, respectively). Conclusion : The thyroid antimicosomal antibodies seemed to be the most important determinant of QoL in patients with autoimmune thyroid disorders.