산삼 약침이 정상인의 심박변이도(HRV)에 미치는 영향

노정두,김락형,송범용,육태한,Roh, Jeong-Du,Kim, Lak-Hyung,Song, Beom-Yong,Yook, Tae-Han 대한약침학회 2008 Journal of pharmacopuncture Vol.11 No.1

Objective : We investigated the effects of distilled Wild Ginseng Herbal Acupuncture on autonomic nervous system with the Heart Rate Variability(HRV) in adult man. as well as we tried to observe how distilled Wild Ginseng Herbal Acupuncture on the balance of the autonomic nervous system. Method : We investigated the effects of distilled Wild Ginseng Herbal Acupuncture on autonomic nervous system with the Heart Rate Variability(HRV) in adult man. as well as we tried to observe how distilled Wild Ginseng Herbal Acupuncture on the balance of the autonomic nervous system. 1 healthy volunteers consisted of 31 subjects in experiment(distilled Wild Ginseng Herbal Acupuncture) group and 30 subjects in control(Normal Saline) group. Study form was a randomized, placebo-controlled, double-blind clinical trial. 31 subjects in experiment group were injected distilled Wild Ginseng Herbal Acupuncture at $GB_{21}$(Kyonjong) and 30 subjects in control group were injected Normal Saline at $GB_{21}$(Kyonjong). except of 2 subjects(in control group) who can't be measured and 11 subjects(7 in experiment group and 4 in control group) who move or make unforceable error during measuring. Finally 24 subject in experiment group and 24 subject in control group are studied. We measured HRV by PolyG-I on 7 times : before and after injection per 5 minutes during 30 minutes. The SPSS 10.0 for windows was used to analyze the data and the paired t-test(in group) and Student t-test(between two groups) were used to verify the result. Result : 1. After distilled Wild Ginseng Herbal Acupuncture injection, Mean HRV is significantly low only for first 5 minute, SDNN is significantly high after 5 minute, Complexity is significantly low after 5 minute, HRV index is significantly high after 10 minute and pNN50 is significantly low after 5 minute. 2. SDNN of distilled Wild Ginseng Herbal Acupuncture Group significantly increased from 20minute to 25minute, and pNN50 of distilled Wild Ginseng Herbal Acupuncture Group significantly decreased from 10minute to 15minute and 20 minute to 30 minute compared with those of Normal Saline group. 3. After distilled Wild Ginseng Herbal Acupuncture injection, Ln(TP), Ln(VLF) and Ln(LF) are significantly high after 5 minute, normalized LF is significantly high after 5 minute and normalized HF is significantly low after 5 minute. 4. Ln(TP) and Ln(VLF) of distilled Wild Ginseng Herbal Acupuncture Group significantly increased from 20minute to 25 minute compared with those of Normal Saline group. Conclusion : The results suggest that distilled Wild Ginseng Herbal Acupuncture in healthy adult man tend to activate the autonomic nervous system and sympathetic nervous system compared to Normal Saline within normal range.

호도약침액의 만성해수(慢性咳嗽)의 현증완화(顯症緩和)에 미치는 영향

노정두,육태한,송범룡,최석우,설현,소웅룡,Roh, Jeong-du,Yook, Tae-han,Song, Beom-ryong,Choi, Seok-woo,Seol, Hyun,So, Woong-ryong 대한침구의학회 2003 대한침구의학회지 Vol.20 No.5

Objective: This study is performed for the purpose of observing the effect of JSD on the cough Methods: 35 patients with the cough treated with JSD herbal acupuncture at 肺兪穴(BL13) and 平喘穴, then self-conscious complain rates were studied. Results: The result as follows. 1. There are remarkable improvement in self-conscious complain rate about chronic cough, sputum, sneezing, runny nose, sore throat, shortness of breath which chronic cough patients complained. 2. There is no significance in self-conscious complain rate according to suffering and treatment period. 3. These result indicates that the effect of JSD herbal acupuncture on chronic cough si exellent.

당귀약침액이 대식세포에서 산화질소(NO) 및 프로스타글란딘 (Prostaglandin) 생성에 미치는 영향

최유진,노정두,Choi, You-Jin,Roh, Jeong-Du 대한약침학회 2011 Journal of pharmacopuncture Vol.14 No.3

Objectives : Angelicae Gigantis Radix has been known traditional medicine with antimicrobial activities and it has been widely used for treatment of blood and inflammatory diseases. In the present study, some studies examined anti-inflammation effects of Angelicae Gigantis Radix but they usually were performed by ethanol extracted Angelicae Gigantis Radix pharmacopuncture. So We investigated the inhibitory effects of Angelicae Gigantis Radix pharmacopuncture by hot water and ethanol extract on Nitric oxide(NO) and Prostaglandin $E_2$($PGE_2$) production in lipopolysaccharide(LPS) induced macrophage cell. Methods : Angelicae Gigantis Radix was extracted by ethanol and hot water. Cell viability was determined by MTT assay. To evaluate anti-inflammation effects of Angelicae Gigantis Radix pharmacopuncture, we examined NO and $PGE_2$ production in LPS induced macrophages. The concentrations of NO and $PGE_2$ were measured by Griess assay and Enzyme Immuno-Assay. Results : 1) The MTT assay demonstrated that cytotoxic effect of Angelicae Gigantis Radix pharmacopuncture by hot water extract and ethanol extract in RAW 264.7 macrophage cells were not appeared. 2) Angelicae Gigantis Radix pharmacopuncture by ethanol extract and hot water extract inhibited NO production in LPS induced macrophages significantly. 3) Angelicae Gigantis Radix pharmacopuncture by ethanol extract tended to inhibiting $PGE_2$ production in LPS induced macrophages. And Angelicae Gigantis Radix pharmacopuncture by hot water extract inhibited LPS induced production of $PGE_2$ in RAW 264.7 macrophage cells significantly. Conclusions : This study suggests that Angelicae Gigantis Radix pharmacopuncture may have an anti-inflammatory property through the inhibition of NO and $PGE_2$ production in LPS induced macrophages. It may have a therapeutic potential for the treatment of various inflammatory diseases.

파열형(破裂型) 요추간판탈출증(腰椎間板脫出症)에 대한임상적(臨床的) 연구(硏究)

신민섭,노정두,최석우,이동호,송범룡,육태한,Sin Min-Seop,Roh Jeong-Du,Choi Seok-Woo,Lee Dong-Ho,Song Bum-Yong,Yook Tae-Han 대한침구의학회 2001 대한침구의학회지 Vol.18 No.6

Objectives : We defined that the ruptured disc is extruded trans ligamentous through the posterior longitudinal ligament or sequestrated. The authors have experienced 12 cases of ruptured disc that underwent the conservative treatment. We studied the effect and possibility of the conservative treatment for the ruptured disc. Methods : The patients with ruptured disc have underwent the conservative treatment. After the treatment, we compare pre-treatment with post treatment in the view of state of patients' ambulation and physical conditions. Results : In this study, 12 cases of ruptured disc have underwent the conservative oriental treatment. After the treatment, 75% of the cases were improved above good state Conclusion : The ruptured disc has been operated universally. Except the emergency state, the conservative treatment is helpful to improve the symptoms of the patients with ruptured disc.

학생표준화환자를 사용한 한의과대학 진료수행시험(CPX)에 대한 학생 인식 조사

조학준,노정두,성현경,박정수,Jo, Hak-Jun,Roh, Jeong-du,Sung, Hyun Kyung,Park, Jeong-Su 대한예방한의학회 2020 대한예방한의학회지 Vol.24 No.3

Objectives : The objective of this survey was to examine students' perception of the clinical performance examination (CPX) in college of traditional Korean medicine using student standardized patients. Methods : College of traditional Korean medicine students who completed the first-semester clinical practice education were selected as the subjects, and they participated in a survey asking questions about the following matters: satisfaction with CPX, self-evaluation, difficulties experienced during the CPX course, level of prior knowledge of clinical practice education, and usefulness of and intimacy with Student Standardized Patients (SSP). Results : Satisfaction with CPX was calculated to be 4.10 (5 being the perfect score), and self-evaluation of CPX was calculated to be 4.12. The subjects chose physical examination as the most difficult item relating to CPX. 80.5% responded positively to the question relating to diverse experiences in practice education, and 52.8% responded positively to the question relating to prior knowledge of diverse standardized patients. 55.6% responded positively to the question relating to performance proficiency of SSP, 63.9% responded positively to the question relating to usefulness of SSP to prepare for CPX, and 69.4% responded positively to the question relating to usefulness of SSP in evaluating CPX, and 55.6% responded positively to the questions relating to intimacy with SSP. It was confirmed that there was a strong quantitative correlation between prior knowledge of clinical practice education and usefulness of SSP, and that there was a strong quantitative correlation between performance proficiency of SSP and usefulness of SSP. It was confirmed that there was a middle-level correlation between performance proficiency of SSP and intimacy with SSP, and that there was a middle-level quantitative correlation between intimacy with SSP and usefulness of SSP. Conclusions : It was confirmed that senior students enrolled in college of traditional Korean medicine were mostly satisfied with the clinical performance examination in college of traditional Korean medicine using SSP, and that usefulness of SSP had a quantitative correlation with prior knowledge of diverse clinical practice educations, performance proficiency of SSP, and intimacy with SSP.

약침을 이용한 수화조절법으로 호전된 갱년기 상열감 및 발한과다 환자 치험 3례

조나영 ( Na Young Jo ),노정두 ( Jeong Du Roh ) 대한한방부인과학회 2015 大韓韓方婦人科學會誌 Vol.28 No.2

Objectives: The purpose of this study is to evaluate the clinical effects of ascending kidney water and descending heart fire pharmacopuncture treatment for hot flush and sweating. Methods: Ascending kidney water and descending heart fire pharmacopuncture is achieved by injecting pharmacopuncture on a specific acupoint to change from the state of water-fire disharmony to harmonious state. Hwangryunhaedok-tang (黃連解毒湯) pharmacopuncture is injected on both side Gyeonjeong (GB21), Pungji (GB20). Total 0.4 cc was injected by 0.1 cc each point. BUM (Bear`s gall bladder, ox bezoar and musk) pharmacopuncture is injected on both side Jeonjung (CV17), Jungwan (CV12), Gihae (CV6). Total 0.15 cc was injected by 0.05 cc each point. Treatment was done daily. The method of evaluation are Hot Flush Score (HFS), VAS and sweating areas. Results: In case 1, after treatment hot flush score was reduced from 24 to 4 points. VAS scale was reduced from 7 to 2. It took about two weeks for the symptoms to decrease by half. Associated symptoms almost did not stay at discharge. In case 2, after treatment hot flush score was reduced from 28 to 2 points. VAS scale was reduced from 10 to 3. And emotional symptoms were reduced about 70%. In case 3, after treatment hot flush score was reduced from 8 to 1 points. VAS scale was reduced from 6 to 1. And headache and chest discomfort symptoms have disappeared. Conclusions: Ascending kidney water and descending heart fire pharmacopuncture treatment is effective for improve ascending kidney water and descending heart fire energy. Therefore, it will be used to alleviate hot flush and sweating.

벨 마비 급성기에 대한 매선요법 병행치료의 임상적 효과

이유정,최연아,김태준,노정두,Lee, You-Jung,Choi, Yeon-Ah,Kim, Tae-Jun,Roh, Jeong-Du 대한한방안이비인후피부과학회 2021 한방안이비인후피부과학회지 Vol.34 No.1

Objectives : This study was to investigate the effectiveness of thread-embedding therapy for the treatment of acute phase of Bell's palsy. Methods : Thread-embedding therapy was performed once a week on 29 patients within 1 weeks after the onset. We investigated the general characters, Yanagihara's score, House-Brackmann scale and FDI were used to evaluate the effectiveness of thread-embedding therapy. Results : Facial muscle recovery began at 13.37th day, that was about 0.36 day earlier than the previous patients who were treated without thread-embedding therapy in 2017 at the same hospital, but there was no statistical significance. In the change of each scale before and after treatment, Yanagihara's score, House-Brackmann scale, physical function and social function of FDI were changed significantly. Compared with the patients treated without thread-embedding therapy in 2017, Yanagihara's score was a little higher and House-Brackmann scale was a little lower. Conclusions : These findings suggested that thread-embedding therapy on acute phase of Bell's palsy was a little more effective than the conventional therapy without thread-embedding therapy.

자연분만 후 발생한 비골신경마비 환자에 대한 Muscle Energy Technique(MET)의 병행치료 효과 증례보고

조나영 ( Na-young Jo ),노정두 ( Jeong-du Roh ) 대한한방부인과학회 2016 大韓韓方婦人科學會誌 Vol.29 No.4

Objectives: The purpose of this study is to evaluate the clinical effects of Muscle Energy Technique (MET) for peroneal nerve palsy after normal delivery. Methods: Two patients with peroneal nerve palsy were treated with acupuncture, moxibustion, cupping and MET. MET was performed in piriform, gluteus medius, anterior tibial and adductor muscles. To evaluate the effect of MET, we analyzed Ankle dorsiflexion range of motion (ROM), Manual Muscle Test (MMT), Numerical Rating Scale (NRS) and Ankle Hindfoot Scale (AHS). Results: In Case 1, ROM score was changed from -5 to 20, and MMT score was changed from 0 to 4. NRS score was changed from 5 to 1, and her AHS score was changed from 54 to 94 after treatment. In Case 2, ROM score was changed from 0 to 20, and her MMT score was changed from 1 to 5. NRS score was changed from 4 to 1, and her AHS score was changed from 64 to 97 after treatment. Conclusions: MET may be a useful treatment for patients who, shortly after childbirth or while breastfeeding, strongly refuse to treat the irritation.

뇌혈관장애환자의 불면증에 대한 이침요법과 신문혈자침 병행시술의 치료효과에 대한 비교연구

소웅룡,박원태,이순호,신경호,노정두,최석우,김제관,So, Woong-ryong,Park, Won-tae,Lee, Sun-ho,Sin, Kyung-ho,Roh, Jeong-du,Choi, Seok-woo,Kim, Jae-gwan 대한침구의학회 2003 대한침구의학회지 Vol.20 No.5

Objective: This study is aimed to compare the change of clinical comfort and improvement after auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7) on insomnia in stroke patients. Methods : Clinical study was carried out on 40 stroke patients who was traeted insomnia by auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7) at Kwang-Dong Oriental Medical Hospital. Results: 1. Total sleeping time was increased in auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7). 2. Average delaying time before sleep and Average Awake Times was decreased in auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7). 3. Quality of sleep was improved in auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7). 4. Insomnia Score was increased in auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7). Conclusions : According to the results, both auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7) were effective on insomnia in stroke patient. but, auricular acupuncture theraphy was more effective than auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7) in total sleeping time and insomnia score.

갱년기 여성의 경항통에 대한 홍화 약침 치료의 임상적 고찰

박재연,윤경진,최유진,김민석,유성진,이참결,노정두,이은용,Park, Jae-Yeon,Yun, Kyung-Jin,Choi, You-Jin,Kim, Min-Seok,Yu, Sung-Jin,Lee, Cham-Kyul,Roh, Jeong-Du,Lee, Eun-Yong 대한약침학회 2011 Journal of pharmacopuncture Vol.14 No.4

Objectives: The purpose of this research was to examine the effect of Carthami-Flos Pharmacopuncture on posterior neck pain of menopausal women. Methods: We treated 20 female patients with neck pain patient(45-60 yr) into two groups and treated Group A with Carthami-Flos Pharmacopuncture and common acupuncture and Group B with common acupuncture. The efficacy of treatment was measured by VAS, NDI and MENQOL scores of before and after 30 days to start treatment. Results: Both group A and B represented effective improvement in VAS and NDI of neck pain and MENQOL scores. And group A was more effective than B group statistically. Conclusions: It was suggested that Carthami-Flos Pharmacopuncture treatment might have effect on posterior neck pain treatment of menopausal women.