芎梔化痰煎과 淸神化痰煎의 면역조절효과

김락형,권진,이광규,정한솔,오찬호 대한동의생리학회,대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.4

This study was performed to evaluate the immunoregulatory effects of Gungchihwadarn-Jeon(芎梔化痰煎, GCHDJ) and Cheongsinhwadarn-Jeon(淸神化痰煎, CSHDJ). GCHDJ or CSHDJ was administered(p.o.) once a day for 14 days to mice. By the treatment of GCHDJ or CSHDJ was increased the cell viability of cultured mice splenocytes, thymocnes and mesenteric lymph node cells. Administration of GCHDJ or CSHDJ was increased the splenic T lymphocyte, especially the Tc cell subpopulation was increased by the GCHDJ, on the while the TH cell was increased by the CSHDJ. The administration of GCHDJ or CSHDJ was significantly increased the apoptosis of transplanted-L1210 leukernia cells to mice peritoneal cavity. These results suggest that GCHDJ and CSHDJ have an immunoregulatory action

산후우울증에 대한 임상적 연구

김락형,김수연,권보형 대한한방신경정신과학회 2000 동의신경정신과학회지 Vol.11 No.2

Objectives: Postpartum depression(PPD) is a kind of serious problem which influences on the postpartum woman, her family and infant. It has been known to be caused by many factors and some depression scales have been used to assess the degree of PPD. Edinburgh Postpartum Depression Scale(EPDS) recently began to be used for screening for PPD. Methods: The subjects were 46 women who admitted for postpartum treatment in Oriental Hospital of Woosuk University from May 2000 to December 2000. In this study, we used EPDS and Beck Depression Inventory(BDI) to assess the degree of PPD, and we researched the related factors of PPD. Results: 13 women(28.3%) in the high risk group by EPDS and 7 women(15.2%) in depression - severe depression group by BDI were diagnosed as PPD among the 46 women. There was significant correlation between Epds score and BDI score. The mean score of EPDS was higher in normal delivery group than caesarean delivery group, higher in primiparae group than multiparae group, and higher in the group who delivered female infants than male infants. But there were not significant differences. And there was not significant correlation between EPDS score and age. Conclusions: These results suggest that PPD is quite frequent at postpartum period and it is necessary to treat for PPD. It is important for clinicians to pay attention to the related factors of PPD as well as to recognize and treat PPD.

성실 그리고 봉임

김락형,Kim, Rak-Hyeong 대한산업보건협회 1999 산업보건 Vol.134 No.-

핵심감정척도와 기질 및 성격검사로 살펴본 사상체질별 심리 특성 연구

김락형 대한한방신경정신과학회 2019 동의신경정신과학회지 Vol.30 No.1

Objectives: The purpose of this study is to investigate the emotional characteristics of the Sasang consti-tution with the Core Seven Emotions Inventory (CSEI) and Temperament and Character Inventory (TCI).Methods: A total of 224 participants were assessed with a Sasang Constitutional Analysis Tool (SCAT) for Sasang Constitution Diagnosis, and completed the Core Seven Emotions Inventory (CSEI) and Temperament and Character Inventory (TCI).Results: 1. From the results of the CSEI, Soeumin showed a significantly higher fear (恐) score than the Soyangin. 2. From the results of the TCI, Soeumin showed a significantly higher harm avoidance (HA) score than Taeeumin and Soyangin. Moreover, the Soyangin showed a significantly higher reward de-pendence (RD) score than Taeeumin and Soeumin. 3. In the correlation tests of the CSEI sub-scales, there was negative correlation between joy (喜) and other emotions, which are thoughts (思), depres-sion (憂), sorrow (悲) and fear (恐). There were positive correlations between the emotions except joy (喜). 4. In the correlation tests of the TCI sub-scales, there was negative correlation between HA and persistence (P), and HA and SD. Moreover, there was a positive correlation between RD and coopera-tiveness (C) and between P and self-directedness (SD). 5. In the correlation tests of the TCI and CSEI, joy (喜) showed a negative correlation with HA and a positive correlation with P and with SD. Anger (怒) showed a negative correlation with C and other emotions except joy (喜) showed a negative cor-relation with RD. Conclusions: The differences of psychological characteristics in Sasang Constitution were shown with CSEI and TCI from this study.

전북지역 일부 남녀 고등학생을 대상으로 한 청소년의 혈압 및 혈중 콜레스테롤에 대한 연구

김락형,강신화,강현철,장인수,Kim Lak-Hyung,Kang Shin-Hwa,Kang Hyon-Chul,Jang In-Soo 대한한방소아과학회 2001 대한한방소아과학회지 Vol.15 No.1

Objective : Hyperlipidemia and hypertension are well recognized risk factors of cerebrovascular disease. So it's very important to evaluate blood pressure and s-cholesterol in adolescence. Material and Methods : April 1999, we were requested health examinaion for high school students of a boys high school and a girls high school in Jeonbuk, Korea. The subjects were 360 students, boys were 317 and girls were 343. They were checked their height, body weight, blood pressure, and s-cholesterol. Results and Conclusion : The mean of systolic blood pressure of study subjects was $111.89{\pm}12.43mmHg$. In boys, it was $116.25{\pm}11.78mmHg$, and in girls, it was $107.87{\pm}11.64mmHg$. The mean of diastolic blood pressure of study subjects was $68.45{\pm}9.40mmHg$. In boys, it was $66.92{\pm}10.00mmHg$, and in girls it was $69.85{\pm}9.40mmHg$. Hypertensives were 18(5.68%) in boys, 10(2.92%) in girls. The mean of s-cholesterol of study subjects was $174.95{\pm}32.28mg/dL$. In boys, it was $178.91{\pm}34.51mg/dL$, and in girls, it was $171.29{\pm}29.66mg/dL$. Hypercholesterolemias were 91(28.71%) in boys, 39(11.37%) in girls. The mean of BMI of study subjects was $21.12{\pm}3.27kg/m2$. In boys, it was $21.05{\pm}3.26kg/m2$, and in girls, it was $21.18{\pm}3.29kg/m2$. Obese boys were 18(5.68%), obese girls were 13(3.79%). The mean of diastolic blood pressure in obese boys was significantly higher than that of normal boys(p=0.001, Mann-Whitney test). The mean of s-cholesterol in obese boys($BMI{\ge}274$) was significantly higher than that of normal boys.(P=0.26, Mann-Whitney test).

농촌주민의 주소증에 대한 조사연구

김락형,김길중,안철호,Kim Lak-Hyung,Kim Gil-Jung,An Chol-Ho 대한예방한의학회 2000 대한예방한의학회지 Vol.4 No.2

Objectives and Methods : This study was conducted to investigate chief complaints among famers. The subjects of this study were 640 famers who live in the rural area in Wanju-gun Jeonbuk province. They were received medical treatment by oriental doctors who visited each village from July 1996 to June 1999. The data of this study were collected from their medical charts . Results and Conclusions : The number of female patients was 449(70.16%) and the number of male patients was 191(29.84%). The group of patients above 70 years was 32.81%, 60-69 years 32.03%, 50-59 years 20.15%, 40-49 years 8.90%, and bellow 39 years 6.09%. The most frequent complaint in farmers was low back pain(27.16%) the second was knee joint pain(16.14%), the third was shoulder Pain(12.06%), and the fourth was headache-dizziness(9.59%). The frequency of musculoskeletal disease(64.48%) was most high, and cardiovascular disease(11.33%) was the second, gstrointestinal disease(10.73%) was the third, respiratory disease(3.42%) was the fourth. It is necessary to pay attention to musculoskeletal disease-especially low back pain and knee joint pain- in study and treatment of farmer's disease.

뇌성마비 언어장애에 대한 한의 치료 연구 동향

김락형,유경,Kim, Lakhyung,Yu, Gyung 대한한방소아과학회 2012 대한한방소아과학회지 Vol.26 No.4

Objectives: The purpose of this study was to obtain some understanding about Korean medicine treatment on language disorder in cerebral palsy for future practice and the research, from the clinical studies. Methods: The literature was searched using the database-China Academic Journals (CAJ). Clinical studies of Korean medicine treatment for language disorder in cerebral palsy, including Randomized controlled trial (RCT), case control study, case series, case report were analyzed. Results: Fifteen Clinical studies met our inclusion criteria; One case study and six case series, one non-randomized controlled trial and seven RCTs. Acupuncture treatment, especially Head acupuncture, was the major treatment for language disorder of cerebral palsy in clinical studies, as it was used in fourteen studies. Acupoint massage, tuina, and acupoint injection were employed as treatment methods in the studies. Acupuncture treatment was used for language disorder of cerebral palsy combined with language therapy and other rehabilitation treatment in many studies. The effectiveness in the treatment groups, regardless of treatment methods, was higher than that of control group in all RCT studies. Conclusions: The results of this study could be used in the practice and the future study about language disorder of cerebral palsy.

전문가 설문을 통한 주의력결핍 과잉행동장애 변증의 주요 증상 빈도 연구

김락형,안윤영,김미연,정민정 대한한방소아과학회 2019 대한한방소아과학회지 Vol.33 No.2

Objectives: The objectives of this study is to investigate the characteristics of Attention-deficit/hyperactivity disorder (ADHD) pattern identification based on the survey of frequencies of symptoms and signs according to the pediatricians and psychiatrists in Korean Medicine. Methods: Eleven pediatricians and fourteen psychiatrists participated in this study. 38 symptoms and signs of 4 ADHD pattern identifications (Kidney yin deficiency and liver yang ascendant hyperactivity 腎虛肝亢, Dual deficiencies in the heart and spleen 心脾兩虛, Phlegm-fire harassing the heart 痰火擾心, Spleen weakness and liver energy preponderance 脾虛肝旺) were used to evaluate the frequencies of ADHD. The differences in frequencies of symptoms and signs amongst ADHD pattern identifications, and the correlations between them were analyzed. Results: There were significant differences in the frequencies of symptoms and signs between each pattern identification. Dual Deficiencies in the Heart and Spleen 心脾兩虛 is negatively related with hyperactivity and impulsivity, and positively related with inattention. Phlegm-fire Harassing the Heart 痰火擾心 is positively related with hyperactivity and impulsivity, and negatively related with inattention. Conclusions: The results of the characteristics of ADHD pattern identifications from the survey analysis could be used in the clinical practices of ADHD as well as to improve the ADHD pattern identification questionnaire.

도시-농촌지역 고등학생의 성장, 혈압 및 혈중콜레스테롤에 대한 연구

김락형,장인수,윤정훈,강신화,강현철,Kim Lak-Hyung,Jang In-Soo,Yun Jeong-Hun,Kang Shin-Hwa,Kang Hyon-Chul 대한예방한의학회 2001 대한예방한의학회지 Vol.5 No.2

Purpose: This study was conducted to investigate and compare the growth, blood pressure, and s-cholesterol of urban and rural students in Korea. Methods: April 1999, We examined the students' health of a boys high school and a girls high school in a urban area - Jeonju, Korea.(boys were 317, girls were 343). And we also examined the students' health of a high school in a rural area - Gimje, Korea.(boys were 33, girls wee 36). Height, body-weight, Body Mass Index(BMI)I, blood pressure, and s-cholesterole were checked and compared between two groups. Results and Conclusion: The mean of height in urban students was $165.25{\pm}7.79cm$, and that in rural students was $163.77{\pm}8.72cm$. There was no significant difference stastically between two groups. The mean of body-weight in urban students $(57.78{\pm}10.51kg)$ was significantly higher than that in rural students $(54.71{\pm}10.11kg)$)(p<0.05). The mean of body mass index(BMI) in urban students $(21.12{\pm}3.27kg/m2)$ was significantly higher than that in rural students $(20.30{\pm}2.69kg/m2)$(p<0.05). Obese students $(BMI{\geq}27)$ were 31(4.70%) in urban students, 3(4.35%) in rural students. The mean of systolic blood pressure in rural students $(114.99{\pm}9.50mmHg)$ was significantly higher than that in urban students $(111.89{\pm}12.42mmHg)$(p<0.05) The mean of diastolic blood pressure in rural students$(75.72{\pm}9.90mmHg)$ was very significantly higher than that of urban students $(68.45{\pm}9.40mmHg)$(p<0.001). Hypertensives (${\geq}138/86mmHg\;in\;boys,\;{\geq}130/83mmHg$ in girls) were 28(4.24%) in urban students, 13(18.84%) in rural students. The mean of s-cholesterol in urban students was $174.95{\pm}32.28mg/dL$, and that in rural students was $176.81{\pm}33.18mg/dL$. There was no significant difference stastically between two groups. Hypercholesterolemias (${\geq}198mg/dL$ in boys, ${\geq}212mg/dL$ in girls) were 130(19.70%) in urban students, 14(20.89%) in rural students. These results suggest that there are differences in body weight, BMI, and diastolic blood pressure between urban and rural students and that it is necessary to consider these differences in health examination.

ADHD 변증 유형별 부주의 및 과잉행동-충동성 증상 특징 연구

김락형,안윤영,김미연,정민정 대한한방소아과학회 2017 대한한방소아과학회지 Vol.31 No.4

Objectives The purpose of this study was to investigate the pattern characteristics of symptoms for ADHD, the relationship between pattern identifications in TKM and TCM and three presentations of ADHD defined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Methods The pattern characteristics of symptoms for ADHD from the 13 Korean and Chinese literatures were analyzed. ADHD symptoms of each pattern were classified into 3 categories; symptoms of inattention, hyperactivity-impulsivity and others. The characteristics of patterns for ADHD in Traditional Medicine were compared with three presentations of ADHD defined in DSM-5. Results 1. The pattern of dual deficiency of the heart and spleen (心脾兩虛) showed predominant symptoms of inattention and rarely showed those of severe hyperactivity and impulsivity. This characteristic of ADHD can be related to the predominantly inattentive presentation in DSM-5. 2. The pattern of phlegm-fire harassing the heart (痰火擾心), and the pattern of deficiency of liver-yin and kidney-yin (肝腎陰虛), frequently showed symptoms of hyperactivity-impulsivity compared with those of inattention. This characteristic of ADHD can be related to the predominantly hyperactive-impulsive presentation in DSM-5. 3. The pattern of spleen weakness and liver energy preponderance (脾虛肝旺) frequently showed both symptoms of hyperactivity, and this characteristic of ADHD can be related to the combined presentation in DSM-5. Conclusions This study showed the relationship between three presentations of ADHD defined in DSM-5 and the pattern identifications of ADHD in TKM and TCM.