사람태아췌장에서 면역조직화학적 방법에 의한 Pancreatic Polypeptide 세포의 위치에 관한 연구

나도영,이원복,김동창 중앙대학교 의과대학 의과학연구소 1988 中央醫大誌 Vol.13 No.2

In order to observe localization of pancreatic polypetide containing cell(pp-cell), we studied this cell immunohistochemically in human fetal pancreas from 9 to 40 weeks of gestation age. 1. PP-cells were found as early as in the 9-week fetus. They were observed between epithelia of a primitive pancreatic tubule. 2. In the 13-week fetus, pp-cells were scattered in primitive pancreatic tubules, in primitive at·mar cells and at peripheral portion of pancreatic islets. 3. In the 18-24 week fetus, pp-cells wore found mainly in exocrine portion, but a few at peripheral portion of pancreatic islets. Thereafter, the number of pp-cell was decreased in exocrine portion while pp-cells were increased in pancreatic islets. 4. In the 26-40 week fetus, a few pp-cells were defected in the exocrine portion and in the ductal system. Pancreatic islets contained pp-cells, were only a few. PP-cells were localized at periphery of the islets. 5. Boring fetal period, the head of pancreas was composed of pancreatic islets which pp-cells took a high percentage of the endocrine cell population. In the mantle islet, one to three pp-cells were identified in peripheral zone.

첨가제가 담배 연기성분에 미치는 영향

나도영,제병권,이창국,조시형,이동욱,Ra Do-Young,J도 Byong-Kwon,Lee Chang-Kook,Cho Si-Hyung,Lee Dong-Wook 한국연초학회 2005 한국연초학회지 Vol.27 No.1

The influence of tobacco additives on the composition of the combustion products in mainstream smoke is discussed. The effect of additives on the chemical composition of smoke have been further evaluated in order to discover additives that would alter the chemical composition of smoke. Tobacco was uniformly treated at a 1-5$\%$ level with 8 classes of additives. Group M treated with alkali metal salt and group S, F, O give lower tar, nicotine and CO values than the control. Group AN treated with natural antioxidant gives higher tar and CO values than the control. The increases are most probably due to the high transfer rate of the ingredients to smoke. M3 and P1 reduced above the $50\%$ of TSNA from the smoke. M4 and P1 reduced above the $50\%$ of HCN from the smoke. These results suggest that tobacco additives alter pyrolysis or combustion product distribution and provide fundamental data to lead the development of a RRP(reduced risk product).

흡연자 및 비흡연자의 뇨중 니코틴 및 코티닌 함량

이문수,나도영,황건중 한국연초학회 1997 한국연초학회지 Vol.19 No.1

This study was conducted to evaluate the personal effects of tobacco smoke and environmental tobacco smoke(ETS) by measuring the concentration of nicotine and cotinine in the urine. While 129 urine samples were being collected, Personal characteristics such as sex, age, number of years since a Person has been a smoker, average consumption number of cigarettes per day, and number of smoker in family were also surveyed. Collected urine samples were used for analysis of nicotine and cotinine by GC/NPD after Passing the extrelut column. In the urine of the smoker, the average contents of nicotine and cotinine were 5.38$\mu\textrm{g}$/ml and 3.14 $\mu\textrm{g}$/ml, respectively. The average contents of nicotine and cotinine were 0.18$\mu\textrm{g}$/ml and 0.07$\mu\textrm{g}$/ml in the urine of male non-smoker, respectively. The contents of nicotine and cotinine in the non-smoker's urine were dependent on sex and age. On the other hand, the contents of nicotine and cotinine in smoker's urine were dependent on average consumption amount of cigarettes per day. Also, there was a direct relation between nicotine levels in the smoker's urine and the average consumption number of cigarettes Per day of smoker. The Possible sources of nicotine and cotinine in the non-smoker's urine seemed to be caused by food, beverage and En, Our results indicate that the number of smoker in family had no effect on increasing nicotine and cotinine contents in the urine of non-smoker.

이분을 이용한 제지식 판상엽의 제조

한영림,나도영,김근수,김삼곤,Han Young-Rim,Ra Do-Young,Kim Kun-Soo,Kim Sam-Kon 한국연초학회 2004 한국연초학회지 Vol.26 No.2

To evaluate utilization of tobacco dust as a raw material of reconstituted tobacco, tobacco dust was applied to the paper-making reconstituted tobacco process and we examined the chemical and physical properties of the reconstituted tobacco and raw materials. The use of tobacco dust in the manufacture of reconstituted tobacco had no measurable adverse effects on the chemical properties of the reconstituted tobacco when added to the reconstituted tobacco formula at levels of $3\%,\;5\%,\;7\%\;and\;10\%$ instead of foreign bright stem. Filling power and fragibility index of the reconstituted tobacco was slightly decreased with increasing tobacco dust levels, but it was not significant change. However, when the level of $10\%$ tobacco dust was added to the reconstituted tobacco formula, the tensile index based basis weight was rapidly decreased.

판상엽 품질 특성 분석 (제1보) - 물리적ㆍ구조적 특성에 관하여 -

한영림,나도영,김삼곤,김근수,강영희 한국연초학회 2004 한국연초학회지 Vol.26 No.1

A comparative analysis of characteristics of domestic and foreign reconstituted tobacco based on papermaking was conducted to evaluate the quality of reconstituted tobacco and to utilize as basic data for improvement of domestic reconstituted tobacco. In the formation, which is key factor to quality and physical properties of product, foreign reconstituted tobacco has better uniform formation than those of domestic one. These result was attributed to distribution of large floc size in the domestic one unevenly. In the fiber morphology, domestic reconstituted tobacco has larger average fiber length and width than those of foreign one. They indicated that fiber morphology of domestic one will exert structural properties of paper such as formation and permeability. Tensile strength of domestic one has lower than those of foreign one by basis weight. In the air permeability, domestic one was remarkably reduced because base web was over sized. It also will affect the combustibility of reconstituted tobacco. In summary, we conclude that the physical and structural properties of domestic reconstituted tobacco result in quality deviations compared with foreign reconstituted tobacco.

잎담배중 유리 및 Glycoside형태로 존재하는 휘발성 향기성분

김영회,나도영,김옥찬,서철원,김용태 한국연초학회 1992 한국연초학회지 Vol.14 No.1

Free and glycosidically bound volatiles from three green tobacco leaves(NC 82, KF 109 and Br-21) were separated by nonionic resin Amberlite XAD-2 adsorption column chromatography and election by selective solvents. Aglycones from the glycosidically bound fractions were released by enzymatic hydrolysis with almond B-glucosidase. A total of 20 components identified from free and glycosidically bound fractions, the major components were benzaldehyde, benzyl alcohol, 2-phenylethyl alcohol, 3-oxo- -ionol, 3-hydroxy-B-ionone, 3-oxo-7, 8-dihydro-n-ionol and scopoletin. Six Cl.B norisoprenoids identified in this study, which have been described to possess a characteristic tobacco aroma-enhancing effect, were not presented in free forms but rather bound glycosidic forms.

환경이 조절되는 Chamber 내에서 Environmental Tobacco Smoke의 생성과 감소 현상

이문수,나도영,안기영,이규서 한국연초학회 1996 한국연초학회지 Vol.18 No.2

This paper describes the generation and decay phenomena of gas, vapor and particulate phase components of environmental tobacco smoke in 18 m3 controlled experimental atmosphere chamber. Real time-weighted average concentration ratios of markers were determinated at no ventilation rates and sampling durations of starting to smoking 45 min. Average concentration of major ETS markers was no significant on the mainstream smoke contents of commercial cigarette and decay ratios were dependent on first order kinetic. RSP/nicotine, solanesol and 3-EP were good predictors of ETS concentration in the public indoor field. The concentration ratio of vapor phase and particulate phase components is highly variable to assessment of indoor air quality with ETS. Key words : ETS, chamber study, ETS markers.

포스터 발표논문 초록 ( 식품분석 / 품질 분야 Poster 초록 ) : 인삼의 휘발성 향기성분 조성

김영희,나도영,김근수,최강주 한국응용생명화학회(구 한국농화학회) 1997 한국응용생명화학회 학술발표회 Vol.1997 No.1

두충껍질의 휘발성 성분

김옥찬,장희진,나도영,박준영 한국농화학회 1990 Applied Biological Chemistry (Appl Biol Chem) Vol.33 No.2

The volatile components of the barks of Eucammia ulmoides Oliver were extracts simutaneous steam distillation-extraction apparatus, and analyzed by combined GC and GC-MS. Forty nine componets, including 4 acids, 11 alcohols, 9 aldehydes, 4 esters, 3 ketones, 16 hydrocarbons, 1 lactone were confirmed in Eucommiae cortexs. Among total volatiles the most component was caproic acid comprising about 18.1%.

원료엽 및 그 배합비율에 따른 부류연중의 니코틴, 탈, 일산화탄소 함량 변화

황건중,이문수,나도영 한국연초학회 1999 한국연초학회지 Vol.21 No.2

This study was conducted to determine the sidestream smoke concentration, nicotine, tar, and CO, by the characteristics of tobacco leaves and their combinations. 20 kinds of tobacco leaves and 15 types of their combinations were selected for this study. After collecting the sidestream smoke by fishtail chimney, the concentrations of nicotine, tar, and CO in sidestream smoke were analyzed. Variation in nicotine concentration of sidestream smoke among tobacco leaves and their combinations was as much as 9-times. Heavy leaves and burley leaves were higher in nicotine concentration than light leaves and flue-cured leaves, respectively, the reconstituted tobacco leaf had the minimum concentration of nicotine. Tar concentration of sidestream smoke also was changed by the characteristics of tobacco leaves and their combinations. As the american C4F had the maximum concentration of tar in sidestream smoke, the reconstituted tobacco leaf showed the minimum concentration. Blending 50 % flue-cured B1-0 plus 50% burley B1-T grade showed the highest value in the nicotine concentration. Also, in case of adding B3K and izmir tobacco leaves, the nicotine concentration was decreased. The tar concentration in the sidestream smoke increased as increasing the amount of flue-cured heavy leaf. The CO concentration was not so much Changed by the characteristics of tobacco leaves and their combinations.