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신이식 후 호전을 보인 Nephrogenic Fibrosing Dermopathy
김훈수 ( Hoon Soo Kim ),김수한 ( Su Han Kim ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),송상헌 ( Sang Heon Song ),김정섭 ( Jung Sup Kim ),곽임수 ( Ihm Soo Kwak ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.2
Nephrogenic fibrosing dermopathy (NFD) is a rare cutaneous fibrosing disorder that primarily affects patients with a history of renal disease. NFD manifests with induration, thickening and hardening of the skin with brawny hyperpigmentation. Lesions are typically symmetrical and usually develop on the limbs and trunk. Flexion contractures of the joints may be a feature of the disease. Histopathological features of NFD include proliferation of dermal fibroblasts and dendritic cells, thickened collagen bundles, increased elastic fibers and focal mucin deposition. Although the pathogenesis remains largely unknown, some of the factors implicated in the pathogenesis include renal dysfunction, circulating fibrocytes, vascular injury, and gadolinium which is a contrast material used in magnetic resonance imaging. Currently, no definitive or uniformly effective therapies are available for the treatment of NFD. We herein describe the case of a 44-year-old female NFD patient who undergoes significant improvement of skin lesions and associated joint contracture after renal transplantation. (Korean J Dermatol 2010;48(2):143∼147)
SUS 304에 대한 Inconel 600의 Sliding 마모거동
김훈,최종현,김준기,박기성,김승태,김선진,Kim, Hun,Choi, Jong-Hyun,Kim, Jun-Ki,Park, Ki-Sung,Kim, Seung-Tae,Kim, Seon-Jin 한국재료학회 2001 한국재료학회지 Vol.11 No.10
The steam generator tubes of power plant damaged by sliding wear due to flow-induced motion of foreign object. Amount of wear have been predicted by Achard's wear equation until now. However, there are large error and low reliability, because this equation regards wear coefficient(k) as constant. The sliding wears tests have been performed at room temperature to examine parameters of wear (wear distance, contact stress). The steam generator tube material for wear test is used Inconel 600 and foreign object material is used 304 austenite stainless steel. The sliding wear tests show that the amount of wear is not linearly proportional to the wear distance(for 374 austenite stainless steel). According to experimental result, wear coefficient is not constant k but function k(s) of wear distance. The newly modified wear predictive equation V=k(s)F have small error and high reliability.
김훈진(Hun Jin Kim),류희선(Hee Seon Ryu),허영회(Young Hoe Hur),김정철(Jung Chul Kim),김신곤(Shin Kon Kim),박찬용(Chan Yong Park) 대한외과학회 2009 Annals of Surgical Treatment and Research(ASRT) Vol.77 No.5
Purpose: We are to describe the clinical characteristics and treatment outcomes in patients aged between 80 and 89 years who underwent inguinal hernia repair under local anesthesia. Methods: We retrospectively reviewed the medical records of patients aged between 20 and 89 years who underwent tension free hernia repair under local anesthesia by a single surgeon between June 2001 and January 2009 and compared clinical characteristics and outcomes between octogenarians who were the eldest and sexagenarians whose incidence was the highest. Results: Of the 514 patients, the number of octogenarians was 52 (8.6%) and sexagenarians were 225 (35.0%). Body mass index (BMI) was 22.5 ㎏/㎡ in octogenarians and 23.7 ㎏/㎡ in sexagenarians (P=0.003). Underlying diseases were present in 67.3% of octogenarians and 73.5% of sexagenarians (P=0.238). The incidence of liver disease was significantly lower in the octogenarians (1.9% vs 15.7%, P=0.004). The proportion of patients who underwent local anesthesia was significantly higher among the octogenarians (94.5% vs 82.2%, P=0.014). Operative time and postoperative hospital stay had no significant difference between both groups. Postoperative complications developed in 4 (7.7%) of the octogenarians and in 18 (9.7%) of the sexagenarians. Scrotal swelling was developed most frequently and surgery-related mortality did not developed in both groups. Conclusion: If local anesthesia is used appropriately, inguinal hernia repair in octogenarians is a safe procedure as like in sexagenarians and may reduce the psychiatric burden related to complications for both surgeons and elderly patients.
병원 2세경영의 리더십 변화가 내부환경 및 조직유효성에 미치는 영향
김훈철 ( Hun Chul Kim ),김영훈 ( Young Hoon Kim ),김한성 ( Han Sung Kim ) 한국병원경영학회 2015 병원경영학회지 Vol.20 No.1
This study aims to examine the effect of a change of leadership on internal environment and organization effectiveness and suggest measures on effective organizational management by analyzing a change of leadership before and after 2nd generation management. There was analysis of a difference of leadership type, organizational structure, organizational culture, management resources, job satisfaction, and organizational commitment between the period of the founders and the period of 2nd generation successors by collecting data from employees of 6 hospitals in Seoul. Also there was analysis of the effect of a change of leadership on internal environment and organizational effectiveness. According to the analysis, it was demonstrated that the factor affecting job satisfaction during the period of the founder was complexity of organizational structure, and there were no factors affecting organizational commitment. In contrast, during the period of the 2nd generation successors, it was revealed that transformational leadership, centralism of organizational structure, and human resources of management resources affect job satisfaction, and transformational leadership, complexity of organizational structure, hierarchical culture of organizational culture, and human resources of management resources affect organizational commitment. Further, after the succession from the founders to 2nd generation successors, as transformational leadership increased, job satisfaction rose, and as developmental culture was reinforced and human resources increased, organizational commitment was heightened. Furthermore, as transformational leadership increased and developmental culture was reinforced, organizational commitment was heightened. Namely, as transformational leadership was reinforced resulting from the succession to 2nd generation, employees`` job satisfaction and organizational commitment increased, with circumstances aiming for the actual change.
무기 박막형 보호층을 이용한 고분자 유기발광 다이오드의 특성 평가
김훈,김광호,김재경,이윤희,한정인,도이미,주병권,Kim, Hoon,Kim, Kwang-Ho,Kim, Jae-Kyung,Lee, Yun-Hi,Han, Jeong-In,Do, Lee-Mi,Ju, Byeong-Kwon 한국전기전자재료학회 2003 전기전자재료학회논문지 Vol.16 No.1
In this study, the inorganic thin-film passivation layer was newly adopted to protect the organic layer from moisture and oxygen. Using the electron beam evaporation system, the various kinds of inorganic thin-films were deposited onto the organic layer and their interface properties between organic and inorganic layer were investigated. In this investigation, the MgO layer showed the most suitable properties, and based on this result, the time dependent emission properties were estimated for the OLED with and without passivation layer. In this experiment, we can see that the time-dependent emission properties of MgO passivated OLED had longer life-time compared to non-passivated OLED. Therefore, we can consider that the MgO thin film is one of the most suitable candidates for the thin-film passivation layer of OLED.
김훈기(Kim, Hoon-gi) 원광대학교 인문학연구소 2017 열린정신 인문학연구 Vol.18 No.2
봉한학설은 1960년대 초반 북한에서 등장했다가 갑자기 사라진 생명학설로서, 인체에 혈관계와 림프관계 외에 새로운 순환계가 존재하며 이는 한의학의 경락체계에 해당한다는 파격적인 주장을 담고 있었다. 당시 소련 과학계는 김봉한 연구실을 방문한 후 긍정적인 평가를 내리며 재현 연구를 시도하려 했지만, 알렉산드로프라는 과학자의 강력한 반발에 부딪혔다. 알렉산드로프는 20세기 중반까지 소련 과학계를 강압적으로 지배해온 리센코주의 생물학자들을 강력히 비판하는 과정에서 봉한학설을 거짓 학설로 단정했다. 이 글에서는 소련 과학계에서 봉한학설이 거부된 배경에 과학적 판단보다는 정치적 이념으로 인한 편견이 중요하게 자리하고 있다는 점을 밝혔다. 알렉산드로프는 봉한학설이 리센코주의 과학자 레페신스카야의 세포기원설와 유사하다고 파악했다. 레페신스카야는 세포가 기존의 세포에서 분열돼 발생한다는 주류 생물학계의 설명을 정면으로 반박하면서 ‘살아있는 물질’인 단백질로부터 세포가 만들어진다고 주장했다. 이에 비해 김봉한 연구진은 DNA를 주요 성분으로 한 ‘산알’로부터 세포가 만들어지고 세포는 다시 산알로 분열된다고 주장했다. 또한 산알이 경락체계를 통해 순환하면서 세포의 갱신을 일으킨다고 파악했다. 두 학설은 단지 물질에서 세포가 만들어질 수 있다는 점에서 공통됐지만, 전체적인 연구의 맥락과 결과는 전혀 다른 것이었다. 그럼에도 알렉산드로프는 봉한학설을 리센코주의의 아류로 인식해 소련에서 재현의 기회 자체를 강력히 저지했다. 이 연구는 새로운 학설이 정치적 편견으로 무시될 수 있고 후대에 다시 과학적으로 평가받을 수 있다는 역사적 사례를 보여주고 있다. The Bong-Han theory was a Life theory that appeared in the early 1960s and suddenly disappeared in North Korea. It contained an extraordinary claim that there was a new circulatory system in addition to the blood vascular system and the lymphatic system in the human body, which corresponded to the meridian system of oriental medicine. Although the Soviet scientific community visited Kim Bong-Han"s laboratory and tried to re-study under positive evaluation, a scientist Alexandrov strongly opposed it. Criticizing fiercely the biologists of Lysenkoism who had oppressively controlled the Soviet scientific community until the middle of the 20th century, Alexandrov judged Bong-Han theory as a pseudoscience. In this article, I pointed out that the prejudice of political ideology was more important than the scientific judgment in the background of the rejection of the Bong-Han theory in the Soviet scientific community. Alexandrov found that the Bong-Han theory was similar to that of Lepeshinskaya, who was one of the scientists of Lysenkoism. Lepeshinskaya argued that the cells could originate from proteins called ‘living substance’, refuting the explanation of the mainstream biology that cells were formed by division in existing cells. In contrast, Bong-Han Kim claimed that the cells were made from ‘sanal’ with DNA as the main ingredient and that cells were again broken down into sanal. Also, sanal circulated through the meridian system and caused cell renewal. Both theories were common in that cells could be made from matter, but the context and outcome of the whole study were quite different. Nevertheless, Alexandrov recognized the concept of the Bong-Han theory as an imitator of Lysenkoism, and strongly inhibited the opportunity of reproduction in the Soviet scientific community. This study shows a historical example that the new scientific theory could be ignored by political prejudice and later be scientifically evaluated again.