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중소기업의 공장.생산설비 자동화에 필요한 교육용 하드웨어 및 소프트웨어 시스템 개발
조성목,김성대,김회진,배석태,손일문,이수룡,조태제,김종철,Cho Sung-Mok,Kim Sung-Dae,Kim Hoe-Jin,Bae Suk-Tae,Son Il-Moon,Lee Soo-Lyong,Cho Tae-Je,Kim Jong-Chul 한국공학교육학회 2000 공학교육연구 Vol.3 No.1
A Factory/Production Facilities Automation involves compound techniques as well as various applied engineering fields. Therefore, there exist lots of difficult problems related with its introduction, operation and management in small and medium scale companies. In this paper, we extract major contents for its effective traininng program reflected from industrial needs and propose a prototype model for the enhancement of its field capabilites. 공장 생산설비 자동화 분야는 다양한 기반기술을 응용하는 분야이다. 중소기업의 입장에서 보면, 공장 생산설비 자동화분야와 관련된 많은 애로 사항이 있다. 본 연구에서는 공장 생산설비 자동화 인력의 효율적인 양성을 위하여 자동화 관련분야의 세부과제들을 현장중심으로 도출하여 현장적응력을 향상시킬 수 있는 교육모형을 제시하고 제작하였다.
자몽종자추출물과 자일리톨이 배합된 껌의 치은염 예방 및 항균효과
진미성,유윤정,최봉규,이희영,김미정,노회진,박종섭,조규성,김종관,최성호,Jin, Mi-Sung,Yoo, Yun-Jung,Choi, Bong-Kyu,Lee, Hee-Young,Kim, Mi-Jung,Roh, Hoe-Jin,Park, Jong-Sub,Cho, Kyoo-Sung,Kim, Chong-Kwan,Choi, Seong-Ho 대한치주과학회 2003 Journal of Periodontal & Implant Science Vol.33 No.3
Grapefruit seed extract has been reported to have antimicrobial effect. The purpose of this study was to evaluate the antimicrobial and anti-gingivitis effect of chewing gum containing grapefruit seed extract and xylitol. 40 healthy subjects with gingivitis or early periodontitis were divided into two groups. Subjects in the experimental group chewed gum containing grapefruit seed extract and xylitol while subjects in the control group chewed gum containing only xylitol. All subjects received scaling and tooth brushing instruction. 1 week after scaling was set as baseline. Gingival index and plaque index were scored at baseline, 1 week, 2 week, 3 week and 4 week. Bleeding index, probing pocket depth and clinical attachment level were scored at baseline, 2 week and 4 week. The number of total bacteria and Streptococcus mutans in unstimulated saliva of experimental group were counted at 1 week, 2 week, 3 week and 4 week. Gingival indices of experimental group and control group at baseline, 1 week, 2 week, 3 week and 4 week were 0.850${\pm}$0.298, 0.575${\pm}$0.345, 0.533${\pm}$0.332, 0.459${\pm}$0.311, 0.408${\pm}$0.224 and 0.758${\pm}$0.379, 0.592${\pm}$0.276, 0.563${\pm}$0.281, 0.454${\pm}$0.194, 0.413${\pm}$0.199 (mean${\pm}$SD), respectively. Plaque indices of experimental group and control group at baseline, 1 week. 2 week, 3 week and 4 week were 0.497${\pm}$0.500, 0.375${\pm}$0.484, 0.332${\pm}$0.471, 0,286${\pm}$0.452, 0.210${\pm}$0.407 and 0.411${\pm}$0.492, 0.375${\pm}$0.484, 0.354${\pm}$0.479, 0.313${\pm}$0.463, 0.193${\pm}$0.395, respectively. Bleeding indices of experimental group and control group at baseline, 2 week and 4 week were 0.377${\pm}$0.177, 0.298${\pm}$0.152, 0.192${\pm}$0.108 and 0.383${\pm}$0.124, 0.318${\pm}$0.153, 0.225${\pm}$0.126, respectively. Probing pocket depth of experimental group and control group at baseline, 2 week and 4 week were 2.56${\pm}$1.00, 2.40${\pm}$0.65, 2.23${\pm}$0.64 and 2.45${\pm}$0.682.37${\pm}$0.57, 2.19${\pm}$0.57, respectively. Clinical attachment level of experimental group and control group at baseline, 2 week and 4 week were 2.58${\pm}$1.01, 2.43${\pm}$0.67, 2.26${\pm}$0.65 and 2.49${\pm}$0.70, 2.40${\pm}$0.59, 2.22${\pm}$0.62, respectively. The % of reduction of total bacteria in saliva of experimental group at 2 week, 3 week and 4 week were 46 ${\pm}$ 53%, 53 ${\pm}$ 5% and 69 ${\pm}$ 33%. The % of reduction of Streptococcus mutans count in saliva of experimental group at 2 week, 3 week and 4 week were 52${\pm}$69%, 88${\pm}$30% and 89${\pm}$17%. From these findings, it can be concluded that regular use of grapefruit seed extract /xylitol chewing gum may be effective to control and prevent gingivitis and may have caries-preventive effect.
Rabeprazole을 포함한 3제요법의 헬리코박터 파이로리 제균 효과와 CYP2C19 유전자형의 영향
이상배 ( Lee Sang Bae ),박상종 ( Park Sang Jong ),류지곤 ( Lyu Ji Gon ),이진광 ( Lee Jin Gwang ),김회진 ( Kim Hoe Jin ),배진수 ( Bae Jin Su ),정현승 ( Jeong Hyeon Seung ),박실무 ( Park Sil Mu ) 대한소화기학회 2003 대한소화기학회지 Vol.42 No.6
Background/Aims: Genetic polymorphism of cytochrome P450 CYP2C19 influences the efficacy of proton pump inhibitor (PPI) in Helicobacter pylori (H. pylori) eradication therapy. We investigated the difference in the cure rates of H. pylori infection by triple (rabeprazole plus amoxacillin and clarithromycin) therapy in relation to CYP2C19 genotype status. Methods: One hundred and sixteen H. pylori infected patients with gastric ulcer and duodenal ulcer completed the triple therapy with 10 mg of rabeprazole b.i.d., 1,000 mg amoxacillin b.i.d. and 500 mg of clarithromycin b.i.d. for one week. The genotype of CYP2C19 was determined by a PCR-restriction fragment length polymorphism method. Results: According to the univariate analysis, heterozygous extensive metabolizers (hetero EMs) and poor metabolizers (PMs) showed the highest (87.0%) and the lowest (80.0%) eradication rates, respectively. The difference in the therapeutic efficacy of rabeprazole among the different CYP2C19 genotypes was insignificant. With regard to gender, age and smoking history in relation to eradication rate, a statistical significance was noted only with age with odds ratio of 1.063 and p-value of 0.0202. Conclusions: In the eradication therapy of H. pylori, no statistically significant difference in therapeutic efficacy of rabeprazole was found among different CYP2C19 genotypes. (Korean J Gastroenterol 2003;42:468-475)