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김홍배,강경화,황원덕,유선애,이승연,Kim, Hong-Bae,Kang, Kyung-Hwa,Hwang, Won-Deuk,Lyu, Sun-Ae,Lee, Seung-Yeon 대한한방소아과학회 2009 대한한방소아과학회지 Vol.23 No.3
Objectives To evaluate that Okwada affected which factors for treatment of lung fibrosis. Methods Bleomycin induced lung fibrosis model made in mice. After Okwada lyophilized, power sample obtained and melt in distilled water. Okwada solution administered mice through oral route on 21 days after bleomycin instillation and this procedure performed once a day for 7 days. We divided by three groups; normal (control), bleomycin induced lung fibrosis without treatment (experimental), bleomycin induced lung fibrosis with treatment (treatment). On six weeks after bleomycin instillation, mice sacrificed and removed lung. We performed Western blot analysis for TGF-beta, phosphodiesterase 5A, interleukin (4,5,13) and compared therapeutic effects of Okwada. Results On western blot analysis, all normal and experimental mice detected TGF-beta, phosphodiesterase 5A, interleukin 4,5,13. The amount of band of TGF-beta, phosphodiesterase 5A, interleukin 5 in experimental and treatment group was similar. However, interleukin 4,13 of treatment group decreased compared with experimental group. Conclusions Okwada would be effected the lung fibrosis through suppression of interleukin 4,13.
Fabrication of InSb TFT and Parameters EXtraction Using Optimization Technique
김홍배,손상희,곽계달,Kim, Hong Bae,Son, Sang Hee,Kwack, Kae Dal The Institute of Electronics and Information Engin 1987 전자공학회논문지 Vol.24 No.1
InSb TFT is fabricated by the vacuum evaporation method and I-V characteristics are measured. Employing Davidon Fletcher-Powell algorithm, the device parameters are extracted. The current-voltage relations calculated by extracdted parameters are in good agreement with experimental results. It is found that optimization technique may be more simple and accurate than curve fitting method in device parameters extration.
升麻葛根湯의 항히스타민 효과 및 IL-4와 GM-CSF 발현에 미치는 영향
김홍배,김원일,이승연,Kim, Hong-Bae,Kim, Own-Il,Lee, Seung-Yeon 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.1
We investigated the effect of Sungmagalkun-tang (SGT) on the allergy. We conformed compound 48/80-induced active systemic anaphylatic shock, anti-dinitrophenyl IgE-mediated passive cutaneous anaphylaxis and ovalbumin-induced anaphylatic shock. Also observed IL-4 and GM-CSF mRNA expression in ovalbumin-induced allergic lung tissue and RBL-2H3. Histamine release is measured in RBL-2H3. SGT inhibited active systemic anaphylatic shock, passive cutaneous anaphylaxis and ovalbumin-induced anaphylatic shock by oral administration. We observed that SGT was concentration-dependently reduced IL-4 and GM-CSF mRNA expression in ovalbumin-induced allergic lung tissue and RBL-2H3 by SGT. In addition, SGT reduced histamine release in RBL-2H3. These results indicate that SGT has anti-histamic effect and controls IL-4 and GM-CSF mRNA expression on allergy.
로버트 벤츄리의 건축에 표현된 양자공존적(兩者共存的) 대입(對立)에 관한 연구 - Mother's House을 중심으로 -
김홍배,이남규,Kim, Hong-Bae,Lee, Nam-Gyu 한국주거학회 2011 한국주거학회 논문집 Vol.22 No.4
This study was conducted to investigate the ambivalent characteristics of dichotomous contradictions expressed by Robert Venturi's architecture. It focused on his Mother's House, which applied his theoretical practices faithfully among many of his architectural works. First, he sought to change interior and exterior spaces by manipulating the architectural scales of "Mother's House". He achieved tension in space through structural complexities in combination with contradictions. Second, as for the characteristics of ambivalent contradictions, including linear and geometric forms, and plane, there were familarity which emphasizes tradition; external appearances of symmetry and asymmetry which give a comfort feeling; openness and closedness, which were expressed with the size of windows and objects such as molding. Third, the fireplace-chimney and the stair were forming appropriate harmony between contradiction and complexity as they competed for central position on the plane.
광주광역시 노후주공아파트 단지의 재건축에 따른 주거단지 변화에 관한 연구
김홍배 ( Hong Bae Kim ) 아시아문화학술원 2016 인문사회 21 Vol.7 No.2
본 연구는 재건축 개발을 앞둔 광주광역시 일대의 노후주공아파트 단지들을 대상으로 개발에 따른 새로운 주거환경의 변화양상을 살펴보고자 한다. 이를 통해 향후 지역별 개발 양상과 노후 공동주택의 재건축 정책방향을 가늠하는 기초자료로 활용하기 위함을 목적으로 하고 있으며, 그 결과 첫째, 재건축개발예정에 따른 개발밀도변화중 건폐율은 아파트단지 3곳 모두 개발 전/후(예정) 큰 변화가 없었다. 그러나 용적률의 경우 단지별로 최소 2.7배(송정주거단지)에서 최대 3.19배(쌍촌주거단지)까지 큰 변화를 보이고 있었다. 둘째, 재건축 개발 전/후(예정)의 층수와 거주밀도의 변화는 재건축에 따른 용적의 증가로 종전 5층의 규모에서 크게 증가되어 지하 1층-3층, 지상 최저 15층-30층까지 높아 졌으며, 또한 각 단지별 세대수도 종전대비 2배가량 증가한 것으로 조사되었다. 셋째, 노후 주거단지의 재건축을 통해 가장 변화 된 측면으로는 3곳 모두 지하1-3층의 지하 주차장 확보, 단지 내 산책로, 어린이 놀이터, 경로당, 체육시설, 휴트니스센터, 도서관 등 주민들을 위한 커뮤니티 공간의 확충이 눈에 띠게 개선되었다. 또한 기존 ○○주공아파트라는 국가 공기업 브랜드를 대신해 국내 사기업(1군 건설업체를 포함) 등이 참여함으로써 재건축에 따른 경제적 가치의 상승효과도 기대하는 것으로 조사되었다. This study is This study aims to investigate the change in residential environments after the reconstruction of old apartment complexes which were built in Gwangju City during 1970s-80s by the Korea National Housing Corporation, not by private construction companies. The findings of this study will be used as base data for determining future policy directions on the reconstruction of old apartment complexes, as well as development patterns in each area. The results of this study can be summarized as follows: First, among density changes after the reconstruction of apartments, there was no big change in the land-to-building ratios before/after (scheduled) the reconstruction of three apartments. In terms of the floor area ratio, some apartment showed an increase by minimum 2.7 times(Songjeong Complex), while others showed an increase by maximum 3.19 times(Ssangchon Complexes). Second, in the aspect of changes in the number of building stories and residential density before/after reconstruction, the number of stories was greatly increased-from the 5-story apartments to apartments with 1-3 basements and 15-30 stories above the ground. The number of households in each complex doubled compared to that of old complexes. Third, noticeable changes after reconstruction included: improvement in community space for residents, such as children playground, senior citizen center, walking paths, sports facilities, fitness center, and library, as well as 1-3 basements of underground parking lot. Particularly, compared to the national brand name “Jugong apartments” citizens expected an increase in property value upon the reconstruction due to participations by Korea’s representative private construction companies in the reconstruction projects.