http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
김현관,박두희,정창균,Kim, Hyun-Kwan,Park, Du-Hee,Jeong, Chang-Gyun 한국토지주택공사 토지주택연구원 2010 LHI journal of land, housing, and urban affairs Vol.1 No.1
국내에서 내진설계의 중요성이 점차적으로 부각되고 있으며 이에 따라 설계 시 동적 지진해석의 수행빈도가 높아지고 있다. 동적 지진해석을 수행하기 위한 가장 중요한 입력변수 중 한가지는 입력지진파이다. 그러나 현재 국내에서는 지진학적 검토 없이 미국, 일본 등에서 계측된 강진 기록을 입력지진파로 사용하거나 주파수영역에서 생성된 인공지진파를 사용하고 있다. 국외 계측 지진기록은 지진 규모에 따라 변화하는 지속시간과 에너지를 고려할 수 없어서 국내 지진환경에는 적합하지 않으며, 주파수 영역에서 생성되는 설계응답스펙트럼에 맞춤형 인공지진파는 실제 지진기록과 주파수 특성이 상이한 문제가 있다. 본 연구에서는 이와 같은 입력지진파의 문제점을 극복하기 위하여 시간영역에서 수행되는 응답스펙트럼 맞춤형 인공지진파 알고리즘을 적용하여 입력 지진파를 생성하였다. 생성된 지진파는 계측 지진기록의 고유한 성질인 Non-stationary 특성을 보존하며 동시에 설계 응답스펙트럼과 거의 완벽한 일치성을 보이는 것으로 나타났다. The importance of seismic design is greatly emphasized recently in Korea, resulting in an increase in the number of dynamic analysis being performed. One of the most important input parameters for the dynamic seismic analysis is input ground motion. However, it is common practice to use recorded motions from U.S. or Japan without considering the seismic environment of Korea or synthetic motions generated in the frequency domain. The recorded motions are not suitable for the seismic environment of Korea since the variation in the duration and energy with the earthquake magnitude cannot be considered. The artificial motions generated in frequency domain used to generated design response spectrum compatible ground motion has the problem of generating motions that have different frequency characteristics compared to real recordings. In this study, an algorithm that generates target response spectrum compatible ground motions in time domain is used to generate a suite of input ground motions. The generated motions are shown to preserve the non-stationary characteristics of the real ground motion and at the same, almost perfectly match the design response spectrum.
Impulse 함수 기반 목표응답스펙트럼 맞춤형 지진파 보정 알고리즘의 적용성 평가
김현관(Kim Hyun-Kwan),박두희(Park Duhee) 한국지반환경공학회 2011 한국지반환경공학회논문집 Vol.12 No.4
동적 지진해석 수행 시 적절한 입력지진파를 선정ㆍ생성하는 것은 매우 중요하다. 현재 국내에서는 일반적으로 국외에서 계측된 강진 기록이나 인공지진파가 입력지진파로 사용된다. 계측지진기록은 지진파의 고유성질인 시간에 따라서 주파수 특성이 변이하는 비정상(Non-Stationary) 특성을 가지고 있지만 설계 응답스펙트럼과는 일치하지 않으며 주파수영역에서 생성된 인공지진파는 설계 응답스펙트럼과는 일치하지만 정상(Stationary) 특성을 가지고 있는 단점이 있다. 본 연구에서는 계측기록의 Non-stationary 특성을 보존하되 동시에 설계 응답스펙트럼에 상응하는 지진파를 생성하였다. 적용된 기법은 Impulse 함수를 이용하여 시간영역에서 지진기록을 목표 스펙트럼에 상응하도록 보정하는 알고리즘이다. 적용 결과, 시간영역 변화 알고리즘은 성공적으로 계측 지진기록을 설계 응답스펙트럼와 일치하도록 조정할 수 있으며 원 지진기록의 Non-stationary 특성을 보존하는 것으로 나타났다. 나아가 계측 지진기록과 보정된 지진기록을 적용한 비선형 지반응답해석을 수행한 결과, 보정된 지진파를 이용한 결과가 보다 합리적인 것으로 나타났다. 본 연구에서 변환된 지진기록은 기존 기록의 문제점을 보완하는 진보된 입력지진파인 것으로 나타났으며 추후 지진해석 시 이를 준용하는 것이 합리적일 것으로 판단된다. Selection or generation of appropriate input ground motion is very important in performing a dynamic analysis. In Korea, it is a common practice to use recorded strong ground motions or artificial motions. The recorded motions show non-stationary characteristics, which is a distinct property of all earthquake motions, but have the problem of not matching the design response spectrum. The artificial motions match the design spectrum, but show stationary characteristics. This study generated ground motions that preserve the non-stationary characteristics of a real earthquake motion, but also matches the design spectrum. In the process, an impulse function-based algorithm that adjusts a given time series in time domain such that it matches the target response spectrum is used. Application of the algorithm showed that it can successfully adjust any recorded motions to match the target spectrum and also preserve the non-stationary characteristics. The modified motions are used to perform a series of nonlinear site response analyses. It is shown that the results using the adjusted motions result in more reliable estimates of ground vibration. It is thus recommended that the newly adjusted motions be used in practice instead of original recorded motions.
Transcriptome analysis reveals stimulus-specific functions of glutamyl-prolyl-tRNA synthetase
이은영,김현관,이종수,김명희 충북대학교 동물의학연구소 2016 Journal of Biomedical and Translational Research Vol.17 No.4
The aminoacyl-tRNA synthetases (ARSs) are ancient house-keeping enzymes that catalyze the ligation of tRNAs to their cognate amino acids in the first step of protein synthesis. During the evolution of higher eukaryotes, cytoplasmic ARSs have undergone significant changes including the addition of new domains that are not part of the enzymatic core. These additional regions have been found to be associated with a broad range of biological functions beyond protein synthesis. The non-translational functions of ARSs appear to be regulated by their presence within a cytoplasmic multi-tRNA synthetase complex (MSC), which is assembled through the appended domains. We recently reported that the MSC member glutamyl-prolyl-tRNA synthetase (EPRS) promotes antiviral gene expression through its infection-specific phosphorylation and release from the MSC. Here, we conducted transcriptome analysis of influenza A virus-infected cells. We particularly focused on the analysis of chemokine-related gene expression, in combination with chemokine array analysis against virus infection. Moreover, the correlation between chemokine expression pattern and EPRS function in response to different stimuli was assessed. The results showed that viral infection increases interferon-response and pro-inflammatory chemokine expression. In contrast, the level of chemokine expression was suppressed in interferon-γ treated cells. Thus, these results further demonstrate the previously reported stimulus-specific EPRS functions in immune responses.
이지현,이재호,김현관,김의검,신귀남,조수현,명창선,김동희,윤미영,최용석,김성훈,송규용,Lee, Jee-Hyun,Lee, Jae-Ho,Kim, Hyun-Kwan,Kim, Eui-Geom,Shen, Gui-nan,Cho, Soo-Hyun,Myung, Chang-Seon,Kim, Dong-Hee,Yun, Mi-Young,Choi, Yong-Seok,Kim, Su 대한약학회 2006 약학회지 Vol.50 No.5
A novel series of 4-senecioyloxymethyl-6,7-dimethoxycoumarin, isolated from Crinum latifolium, was prepared by reacting 4-bromomethyl or 4-bromomethyl-6,7- dimethoxycoumarin with various carboxylic acids and examined for their anti-angiogenic activities in human umbilical vein endothelial cells (HUVECs). Among them, 4e, 4f, 4g and 4i with noncyclic moiety exhibited potent anti-angiogenic activity. However, compounds with cyclic moiety such as phenyl, pyridinyl, thiophenyl and furanyl group did not exhibit any anti-angiogenic activity. Also, compounds 4f and 4g which exhibited strong anti-angiogenic activity in a dose-dependent manner showed antitumor activity.
곽재영(Jae-young Gwarg),김현관(Hyun-kwan Kim),송상빈(Sang-bin Song),여인선(In-seon Yeo) 한국조명·전기설비학회 1994 한국조명·전기설비학회 학술대회논문집 Vol.1994 No.-
Recently compact fluorescent lamps are widely used in downlight luminaires, so the needs of dimming of electronic ballasts for the lamps are greatly increased. This paper presents a new approach in the design of electronic ballasts for dimming compact fluorecent lamps by using PSpice simulation to determine the circuit parameters of the resonant-tank circuit. A prototype of an electronic dimming ballast which adopts half-bridge inverter topology is set up to compare the results of PSpice simulation with experimental ones, and thus to verify the validity of the proposed method.