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Coronary-artery Calcium Scores Using Electron Beam CT in Patients with Chronic Renal Failure
김찬덕,조지형,최혁준,장민화,권혁만,김준철,박선희,이종민,조동규,김용림 대한의학회 2005 Journal of Korean medical science Vol.20 No.6
We evaluated the risk of coronary-artery disease in patients with chronic renal fail-ure (CRF) by measuring the coronary-artery calcium scores with electron beam CT (EBCT). A total of 81 CRF patients were divided into three groups; pre-dialysis (group I, n=35), hemodialysis (group II, n=31) and peritoneal dialysis (group III, n=15). The several serum biochemical markers and calcium score levels by EBCT were determined. The Ca ×P products were significantly higher in groups II (p<0.05) and III (p<0.01) than in group I. The serum calcium levels were significantly higher in group III than in both group I (p<0.01) and II (p<0.05). The serum calcium level in 15 patients with a calcium score > 400 was significantly higher than the 66 patients with a score ≤400 (p<0.01). The calcium score was significantly higher in the 15 patients with cardiovascular complications than in the 66 patients without cardiovas-cular complications (628.9 ±904.8 vs. 150.4 ±350.9, p<0.01). EBCT seemed to be a good diagnostic tool for evaluating the risk of coronary-artery disease ‘‘non-invasively’’ in CRF patients who are at increased risk of cardiovascular morbidity and mortality.
일반연제 발표 : 저 포도당 대사산물 복막투석액의 사용이 복막염증, 복막의 구조적 변화 및 복막 혈관생성 지표들에 미치는 영향
김찬덕 ( Kim Chan Deog ),김용림 ( Kim Yong Lim ),도준영 ( Do Jun Yeong ),박선희 ( Park Seon Hui ),조규향 ( Jo Gyu Hyang ),박종원 ( Park Jong Won ),윤경우 ( Yun Gyeong U ),조동규 ( Jo Dong Gyu ),이은계 ( Lee Eun Gye ),김인산 ( Kim 대한신장학회 2003 춘계학술대회 초록집 Vol.22 No.1
김찬덕 ( Chan Duck Kim ) 대한내과학회 2014 대한내과학회지 Vol.86 No.2
Kidney transplantation is the treatment of choice for end stage renal disease. Successful kidney transplantation improves the quality of life and reduces the mortality risk for most patients, when compared with maintenance dialysis. Recent advances, including immunosuppressants, desensitization treatment for highly sensitized kidney transplant candidates, and better medical care, have resulted in an increase number of transplants with improved outcomes. However, kidney transplant recipients require close follow-up after transplantation since they are on complex immunosuppressive regimens that render them susceptible to infection, malignancy, and cardiovascular disease. The additional obstacles of kidney transplantation include the lack of improvement in long term outcomes, shortage of organs, and multiple co-morbidities due to their underlying chronic kidney disease. To improve the long-term outcome of renal allograft, physicians must be aware in developing newer immunosuppressive regimens, with lower side effects, and reduction of death with functioning graft and chronic allograft dysfunction will be the greatest challenge of all physicians who care for kidney transplant recipients. This review highlights current status of kidney transplantation in Korea, brief transplant immunology, immunologic tests, donor/recipient evaluation, immunosuppressive medications, and complications of kidney transplantation involving rejection, post transplantation infections, malignancy, cardiovascular disease and recurrence of primary disease. (Korean J Med 2014;86:142-151)