고지방식이로 유도된 비만 마우스에서 바실러스균을 이용한 발효대두의 혈행개선 효과

김진솔,정준한,양은주,이호우,이현화 한국산학기술학회 2022 한국산학기술학회논문지 Vol.23 No.8

This study investigated the effect of fermented Glycine max using B. velezensis L2 on improved blood flow in high fat-diet induced obese mice. Briefly, 9-week-old male Balb/c mice were fed a high-fat diet for three weeks, after which the high-fat diet and lovastatin or fermented G. max extract were administered for two weeks. Depending on the diet, the animals were randomly divided into five groups of five mice each: normal diet group(ND), high-fat diet group(HFD), lovastatin 50 mg/kg/day group(Lovastatin 50), fermented G. max extracts 1,000 and 2,000 mg/kg groups (FGM 1000 and FGM 2000, respectively). Weight gain and food efficiency of each mouse in each group were measured every two days. The organ weight, cholesterol and triglyceride contents, tail bleeding time, and platelet aggregation rate were measured at the end of the experiment. Our results showed significantly increased weight gain in the HFD group compared with ND group. In the FGM 2000 group, the contents of cholesterol and triglyceride were significantly lower and the animals had a significantly prolonged bleeding time compared with the HFD group. In addition, the collagen-induced platelet aggregation showed the highest platelet aggregation inhibition rate in the FGM 2000 group. These results indicate that fermented G. max using B. velezensis L2 has the potential to be used as functional materials to prevent and improve hyperlipidemia. 본 연구는 고지방식이로 비만이 유도된 마우스에서 B. velezensis L2 균을 이용한 발효대두 섭취를 통한 마우스의 혈행개선 효과를 조사하였다. 9주령의 Balb/C 수컷 마우스에 3주간 고지방식이를 실시하여 비만을 유도한 후 2주 동안 고지방식이와 함께 매일 lovastatin과 발효대두 추출물을 경구투여 하였으며, 실험군은 일반식이군, 고지방식이군, Lovastatin 50 mg/kg/day, 발효대두 1,000 mg/kg, 2,000 mg/kg 경구투여군으로 나누어 각 군에 무작위로 5마리씩 배정하여 실험하였다. 실험군의 체중증가량, 식이효율을 측정하였으며 실험종료 후 각그룹 마우스의 장기무게, 혈중 총콜레스테롤 및 중성지방 농도, tail bleeding time, 혈소판 응집도를 측정하였다. 실험결과, 고지방식이군은 일반식이군에 비해 유의적으로 체중이 증가하여 비만이 유도됨을 확인하였다. 고지방식이로 유도된 비만마우스의 혈중 콜레스테롤과 중성지방의 농도는 고지방식이군에 비해 발효대두 2,000 mg/kg 군에서 유의적으로 감소하였으며 발효대두 2,000 mg/kg 군의 tail bleeding time은 고지방식이군 대비 유의적으로 연장되었고 또한 collagen에 의한 혈소판 응집반응은 발효대두 2,000 mg/kg 군에서 높은 혈소판 응집억제율을 보였다. 따라서, 이러한 결과는 B. velezensis L2 균을 이용한 발효대두는 고지혈증을 예방하고 개선하기 위한 기능성 소재로 활용이 가능할 것으로 판단된다.

"인성교육 방법으로서의 도덕 판단력 활용방법"에 대한 논평

김진솔 한국초등도덕교육학회 2015 한국초등도덕교육학회 학술대회 Vol.2015 No.-

어반 보이드

김진솔,유원선,김한솔,조혜연 한국디자인사학회 2023 Extra Archive: 디자인사연구 Vol.- No.6

관심중심수용모형(CBAM)을 활용한 초등교사의 SW교육 관심도 및 실행수준 분석

김진솔,이정민 한국콘텐츠학회 2020 한국콘텐츠학회논문지 Vol.20 No.8

본 연구에서는 초등교사의 SW교육에 대한 관심도 및 실행수준을 관심중심수용모형(Concerns-Based Adoption Model)을 통해 분석하여 SW교육의 지속적인 현장 적용을 위한 교사교육에서의 시사점을 도출하고자 하였다. 이를 위해 현직 초등학교 교사 152명을 대상으로 설문을 실시하였고, 수집된 데이터를 분석하였다. 연구 결과, 초등교사의 SW교육에 대한 관심도는 0단계(지각)부터 2단계(개인) 측면의 관심이 높은 초기 관심 단계를 보이고 있었다. 현재 SW교육을 실행하고 있는 교사는 현장에서 SW교육을 단기적으로 시행하는 것에 집중하는 기계적 실행과 일상화 수준에 있는 것으로 나타났으며, 실행하고 있지 않은 교사의 과반수는 SW교육을 실행하기 위한 의도가 없는 것으로 나타났다. 교사의 성별, 교직경력, SW연수경험, SW교수경험에 따라 교사의 SW교육 관심단계에 유의미한 차이가 나타났으며, 담당학년, SW연수경험, SW교수경험에 따라 SW교육 실행수준에 유의미한 차이가 있었다. 이러한 결과를 바탕으로 현직 초등학교 교사들의 SW교육 관심 변화를 촉진하기 위한 방안을 교사를 대상으로 한 다양한 SW교육 제공 및 교수경험 확대의 측면에서 제안하였다. The purpose of this study is to examine teachers’ stages of concern and levels of use about SW education based on Concerns-Based Adoption Model and to provide implications for teacher education. For this purpose, 152 survey responses were collected from elementary school teachers in South Korea. The result indicated that elementary school teachers’ concerns about SW education showed the nonuser pattern in that teachers score highest in stage 0(awareness) to stage 2(personal) and in stage 6(refocusing). Additionally, teachers who are currently implementing SW education showed a tendency to be in the level of mechanical use or routine, and more than half of the teachers who are not implementing SW education showed no motivation to change current practices. There were statistically significant differences in the stages of concern depending on gender, teaching experience, SW training experience, SW teaching experience, and there were differences in the levels of use depending on the teachers’ grade level in charge, SW training experience, and SW teaching experience. Based on the results of the research, various SW related programs as well as successful SW education experience for teachers need to be provided for teacher education in order to promote SW education.

에미터 도핑 농도와 Al2O3 페시베이션 막 특성 평가

김진솔,최동진,강동균,박현정,배수현,강윤묵,이해석,김동환 한국진공학회 2020 한국진공학회 학술발표회초록집 Vol.2020 No.2

지속가능한 배움의 공동체 : 대학 친구들이 수업 공동체가 되기까지

김진솔 전국국어교사모임 2023 함께여는 국어교육 Vol.- No.150

탈피대두를 이용한 신속 두유 제조 및 품질 특성

김진솔,한인범,정의환,차승현,현태경,김순환,하진석,장금일,Kim, Jin-Sol,Han, In-Bom,Jung, Ui-Hwan,Cha, Seung-Hyeon,Hyun, Tae Kyung,Kim, Soon-Hwan,Ha, Jin-Seok,Jang, Keum-Il 한국식품영양학회 2019 韓國食品營養學會誌 Vol.32 No.6

The purpose of this study was to investigate the quality of dehulled soybean (DHSB), and the rapid preparation possibility of soybean milk with DHSB (SM-DHSB), and then the quality of SM-DHSB. In DHSB, the moisture content decreased, the crude protein, crude fat, minerals, and carbohydrate contents increased, and the isoflavone (daidzein, genistein and glycitein) content was similar to that of soybean (SB). The water absorption rate of DHSB for soybean milk preparation was higher than that of SB. In the results of SM-DHSB and soybean milk (SM) qualities, the crude protein content, total solid content, and the viscosity of SM-DHSB were higher, the yield and the proximate composition (except crude protein) were similar, and the Biji production rate, and total dietary fiber content of SM-DHSB were lower compared to the SM. In terms of the isoflavone contents of SM-DHSB, daidzein and genistein content were similar, and glycitein content was lower compared with the SM. Consequently, these results suggest the possible use of DHSB for rapid SM-DHSB preparation, because the soaking time was decreased by the high water absorption rate of DHSB in the SM preparation, and the quality of SM-DHSB improved compared to those of the SM.

ICR 마우스에서 황칠 추출물의 유전독성 및 단회 투여 급성 독성

김진솔,정민주,송선영,이현화,정준한 대한미용학회 2020 대한미용학회지 Vol.16 No.3

The current study evaluated the safety of Dendropanax morbifera extract in the ICR mouse by testing both genotoxicity and single-dose toxicity of the compound. Compared to a negative control, the micronucleus test indicated no significant increase in the number of micronucleus polychromatic erythrocytes (MNPCE) in polychromatic erythrocytes (PCE), detected in the Dendropanax morbifera extract at 250, 500, or 750 mg/kg. Similarly, there were no changes in the rate of PCE/(PCE+NCE) in Dendropanax morbifera extract compared to the negative control group, though there was a significant decrease in the positive control group (p<0.05). In the single oral dose toxicity test, there were no significant changes in clinical signs, body weight, organ weights or gross observation compared to the negative control group. The serum biochemical examination indicated that compared to the negative control group, the ALP level was significantly increased in female mice at doses of 500 and 750 mg/kg of Dendropanax morbifera extract (p<0.05), however there was no significant difference in the correlated liver index test items such as AST and ALP. Histopathological observations revealed no change between treatment and negative control groups in liver or kidney tissues. Taken together, these results found no observed adverse effect level (NOAEL) of the single oral application of Dendropanax morbifera extract up to 750 mg/kg in mice. Based on these findings, we suggest that Dendropanax morbifera could be used as a non-toxic natural material for functional cosmetics, food, and medicine development.

Overcoming the Hurdles of Transition: Middle School Students’ Engagement in Distance Instruction During the COVID-19 Pandemic in South Korea

김진솔,이정민 한국교육공학회 2023 Educational Technology International Vol.24 No.1

The study aimed to qualitatively examine middle school students’ engagement in distance instruction during the COVID-19 pandemic. The participants comprised 119 students from a girls’ middle school in Seoul, South Korea. To gain an in-depth understanding of the students’ experiences, we collected their reflective journals, which included structured items about their learning engagement at three timepoints in 2020: April, July, and December. The following are the results: 10 themes and 18 concepts were derived, and they were integrated into causal conditions (sudden transition due to COVID-19), contextual condition (technology readiness, school education context), central phenomena (high level of behavioral engagement, low emotional engagement), interventional conditions (recognizing the potential of online learning, situational awareness about COVID-19 and online learning), action/interaction phenomena (development and use of self-regulated learning strategies), and consequences (changes in practices and perception towards online learning). Based on the findings, engagement patterns of the participants were classified into five types: proactive, conservative, receptive, reactive, passive learners. The present study demonstrated important findings that are essential for the improvement and development of engaging online learning strategies in the future.

Surface Wind Regionalization Based on Similarity of Time-series Wind Vectors

김진솔,김현구,박형동 한국대기환경학회 2016 Asian Journal of Atmospheric Environment (AJAE) Vol.10 No.2

In the complex terrain where local wind systems are formed, accurate understanding of regional wind variability is required for wind resource assessment. In this paper, cluster analysis based on the similarity of time-series wind vector was applied to classify wind regions with similar wind characteristics and the meteorological validity of regionalization method was evaluated. Wind regions in Jeju Island and Busan were classified using the wind resource map of Korea created by a mesoscale numerical weather prediction modeling. The evaluation was performed by comparing wind speed, wind direction, and wind variability of each wind region. Wind characteristics, such as mean wind speed and prevailing wind direction, in the same wind region were similar and wind characteristics in different wind regions were meteor- statistically distinct. It was able to identify a singular wind region at the top area of Mt. Halla using the inconsistency of wind direction variability. Furthermore, it was found that the regionalization results correspond with the topographic features of Jeju Island and Busan, showing the validity.