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김웅준 ( Woong Jun Kim ),은창수 ( Chang Soo Eun ),이민규 ( Min Kyu Lee ),민승연 ( Seung Yeon Min ),유연화 ( Yeon Hwa Yoo ),한동수 ( Dong Soo Han ),전용철 ( Yong Cheol Jeon ),손주현 ( Joo Hyun Sohn ) 대한장연구학회 2012 Intestinal Research Vol.10 No.2
A chronic intestinal pseudo-obstruction is a rare disorder and a severe digestive syndrome. It is characterized by deranged gut propulsive motility that resembles a mechanical obstruction, but no obstructive process is present. An intestinal pseudo-obstruction may be classified as acute or chronic; the chronic form may also be classified as idiopathic or secondary to a variety of diseases. Treatment of intestinal pseudo-obstruction involves nutritional, pharmacological, and surgical therapies. Surgery should be limited to patients who are refractory to medical therapy and show a deteriorating course. Despite available medical and surgical interventions, the outcome remains poor. Here, we describe a case of a 54-year-old female with chronic constipation and abdominal distension, who was subsequently found to have segmental aganglionosis. The patient was treated with a subtotal colectomy and ileosigmoidostomy without sequelae. (Intest Res 2012;10:210-214)
증례 : 일과성 뇌허혈과 심근병증으로 발현한 갈색세포종 1예
김웅준 ( Woong Jun Kim ),김해수 ( Hae Su Kim ),김석환 ( Seok Hwan Kim ),신정훈 ( Jeong Hun Shin ),신진호 ( Jin Ho Shin ),김정현 ( Jeong Hyun Kim ),임영효 ( Young Hyo Lim ) 대한내과학회 2012 대한내과학회지 Vol.83 No.2
본 증례에서 환자는 내원 6개월 전 일과성 뇌허혈이 있었고, 흉통을 호소하며 내원하여 심전도 및 심근효소에서 급성관상동맥 증후군이 의심되어 관상동맥조영술을 시행하였으나 관상동맥에는 특이 소견이 없었고, 좌심실 조영술에서 Takotsubo 심근병증 양상으로 나타났다. 내원 6개월 전에 있었던 일과성 뇌허혈 및 Takotsubo 심근병증이 모두 갈색세포종에서 드물게 보일 수 있는 양상이었으며, 발작적인 고혈압, 두통, 심계항진 등의 동반 증상 등으로 갈색세포종을 의심하였고, 복부 전산화단층촬영 및 24시간 요 카테콜라민 검사에서 확인이 되어 수술적 치료로 호전이 된 증례이다. Patients with pheochromocytoma show a variety of clinical symptoms secondary to excessive catecholamine secretion. Major symptoms include hypertension, headache, hyperhidrosis, and palpitation. Stroke and myocardial infarction are known to occur in patients with pheochromocytoma, but the incidence is low. Here, we describe a 45-year-old female with a previous history of transient ischemic attack and a clinical presentation mimicking acute myocardial infarction with transient takotsubo-like myocardial dysfunction. A subsequent diagnostic examination revealed a left adrenal pheochromocytoma. The patient recovered with intensive medical treatment, including alpha- and beta-adrenergic blockade. Follow-up echocardiography revealed normalized cardiac function and wall motion. Thereafter, the patient underwent a laparoscopic left adrenalectomy without complications.
만성 C형 간염 복막 투석 환자에서 Pegylated Interferon Alpha-2a 치료
태혜진 ( Hye Jin Tae ),전대원 ( Dae Won Jun ),최종욱 ( Jong Wook Choi ),김웅준 ( Woong Jun Kim ),김봉영 ( Bong Young Kim ),손주현 ( Joo Hyun Sohn ),이민호 ( Min Ho Lee ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.2
Pegylated interferon (PEG-IFN) is now the standard treatment for chronic hepatitis C. But, there are few reports about patients with end stage renal disease, and treatment protocol for HCV infection has not been determined, particularly in patients on peritoneal dialysis. We experienced a case of a peritoneal dialysis patient with chronic hepatitis C who was successfully treated with PEG-IFN monotherapy. A 50-year old man was undergoing peritoneal dialysis because of diabetic nephropathy. Considering that his HCV genotype was 2, we decided to treat him with PEG-IFN alpha-2a monotherapy 4 month after the beginning of peritoneal dialysis. We adopted a 90 μg of PEG-IFN administration. After the injection of PEG-IFN, dialysate concentration of PEG-IFN did not change significantly. HCV-RNA disappeared at the 4th week and sustatined virus response was achieved thereafter. No side effects were observed during the treatment of 24 weeks. PEG-IFN monotherapy with dose modification may be a safe and effective treatment for HCV infection in patients undergoing peritoneal dialysis. (Korean J Gastroenterol 2011;58:107-110)
이민규 ( Min Kyu Lee ),김병식 ( Byung Sik Kim ),정석현 ( Suk Hyun Jung ),이건화 ( Gun Hwa Lee ),김진옥 ( Jin Ok Kim ),임동휘 ( Dong Hwi Rim ),이유화 ( Yu Hwa Lee ),김웅준 ( Woong Jun Kim ),방소영 ( So Young Bang ),이혜순 ( Hye Soo 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.3
Klinefelter`s syndrome which is characterized by hypogonadism with karyotype abnormality (47 XXY or 46 XY/47 XXY) in males has been reported to be associated with autoimmune diseases including rheumatoid arthritis and systemic lupus erythematosus. However, Klinefelter`s syndrome accompanying with polymyositis has rarely been reported. We report a case of KFS with polymyosits in a 38-year old man for the first time in Korea.
송준석 ( June Seok Song ),이건화 ( Gun Hwa Lee ),이민규 ( Min Kyu Lee ),김웅준 ( Woong Jun Kim ),이승호 ( Seung Ho Lee ),김상헌 ( Sang Heon Kim ),김태형 ( Tae Hyung Kim ),윤호주 ( Ho Joo Yoon ),신동호 ( Dong Ho Shin ),박성수 ( Sun 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.71 No.6
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia occurring in Western nations. In CLL it is well known that the risk of a secondary malignancy is higher than in the normal population. But in Korea, CLL is a rare type of leukemia, so there have been only a few reported cases with a secondary malignancy. CLL is characterized by progressive defects in both cell-mediated and humoral immunity. It is known that defects in the immune system of patients with CLL contribute to the development of a secondary malignancy. We experienced a case of a 71-year-old man who suffered from a chronic cough and was diagnosed with small cell lung cancer coexisting with CLL. Until this case, there was no reported case in Korea of small cell lung cancer coexisting with CLL. We now report a case of small cell lung cancer coexisting with CLL and present a literature review.