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      • SCOPUSKCI등재

        만성 C형 간염 복막 투석 환자에서 Pegylated Interferon Alpha-2a 치료

        태혜진 ( Hye Jin Tae ),전대원 ( Dae Won Jun ),최종욱 ( Jong Wook Choi ),김웅준 ( Woong Jun Kim ),김봉영 ( Bong Young Kim ),손주현 ( Joo Hyun Sohn ),이민호 ( Min Ho Lee ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.2

        Pegylated interferon (PEG-IFN) is now the standard treatment for chronic hepatitis C. But, there are few reports about patients with end stage renal disease, and treatment protocol for HCV infection has not been determined, particularly in patients on peritoneal dialysis. We experienced a case of a peritoneal dialysis patient with chronic hepatitis C who was successfully treated with PEG-IFN monotherapy. A 50-year old man was undergoing peritoneal dialysis because of diabetic nephropathy. Considering that his HCV genotype was 2, we decided to treat him with PEG-IFN alpha-2a monotherapy 4 month after the beginning of peritoneal dialysis. We adopted a 90 μg of PEG-IFN administration. After the injection of PEG-IFN, dialysate concentration of PEG-IFN did not change significantly. HCV-RNA disappeared at the 4th week and sustatined virus response was achieved thereafter. No side effects were observed during the treatment of 24 weeks. PEG-IFN monotherapy with dose modification may be a safe and effective treatment for HCV infection in patients undergoing peritoneal dialysis. (Korean J Gastroenterol 2011;58:107-110)

      • KCI등재

        세월호 참사 후 희생자 부모의 건강상태 변화

        양상은,태혜진,황지현,채정호,Yang, Sang Eun,Tae, Hye Jin,Hwang, Jihyun,Chae, Jeong-Ho 대한불안의학회 2018 대한불안의학회지 Vol.14 No.1

        Objective : The present study had examined the psychiatric symptoms and physical health consequences for the bereaved parents of the high school students who died in the 2014 Sewol ferry accident. Methods : Forty bereaved parents participated in the study. The authors administered self-report questionnaires about the parents' health behaviors and psychiatric symptoms. The authors also conducted laboratory tests to assess the parents' physical health at 18 and 30 months after the accident. Univariate descriptive statistics were performed to report the prevalence and severity of psychiatric symptoms and health-related behaviors. Paired t-test and Mcnemar test were performed to compare the 18-and 30-month findings. Correlation analysis between psychiatric symptoms and laboratory findings were performed to find a relationship between the two variables. Results : At 30 months after the accident, most of the bereaved parents still appeared to suffer from complicated grief (97.5%), post traumatic stress disorder (80%), insomnia (77.5%) and severe depression (62.5%) based on the scores on the Inventory of Complicated Grief (ICG), the PTSD Check List-5 (PCL-5), the Insomnia Severity Index (ISI) and the Patient Health Questionnaire-9 (PHQ-9). One quarter of the bereaved parents reported high-risk drinking, and 47.5% reported increased drinking amount and frequency after the accident. In objective laboratory results, 55% of the bereaved parents were obese as defined by body mass index ${\geq}25$. The parents' mean low-density lipoprotein shows a significant increase over time (118.5 mg/dL at 18 months. vs. 132.5 mg/dL at 30 months. paired t-test t=-4.061, $$p{\leq_-}0.001$$). Total cholesterol and low-density lipoprotein at 30 months after the accident were in clinically borderline high range. In correlation analysis, triglyceride was positively correlated with ISI. Conclusion : The loss of children in the Sewol ferry accident, a disaster caused by human error, continued to have considerable impact on the victims' parents' mental and physical health 18 and 30 months after the accident. A longitudinal study following the parents' physical health would be necessary to investigate the long-term effects of this traumatic experience on physical health.

      • KCI등재

        류마티스관절염 환자에서 Infliximab 사용 후 발생한 심방세동 1예

        최종욱 ( Jong Wook Choi ),태혜진 ( Hye Jin Tae ),오일환 ( Il Hwan Oh ),이민규 ( Min Kyu Lee ),신진호 ( Jin Ho Shin ),김태환 ( Tae Hwan Kim ),전재범 ( Jae Bum Jun ),엄완식 ( Wan Sik Uhm ) 대한류마티스학회 2011 대한류마티스학회지 Vol.18 No.4

        국내에 종양괴사인자억제제 사용 중 발생한 부정맥에 대한 보고가 없었으며 저자들은 류마티스관절염의 치료로 infliximab을 사용한 후 심방세동이 발생된 환자를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Infliximab, a chimeric monoclonal immunoglobulin antibody to tumor necrosis factor (TNF)-α is widely used in the treatment of rheumatoid arthritis (RA). The commonly reported cardiac side effects of infliximab include exacerbation of congestive heart failure, hypotension, and syncope. Cardiac arrhythmia and conduction disturbances have been reported only rarely in a few case reports and to the best of our knowledge, there are no previous reports on the occurrence of atrial fibrillation secondary to infliximab use in RA patients. Here, we report a case of acute atrial fibrillation with rapid ventricular response that occurred 24 hr after first dose of infliximab in a 55-year-old female patient with RA, who recovered to sinus rhythm after pharmacologic management.

      • KCI등재

        간질성 신염을 동반한 자가면역성 췌장염

        이유화 ( Yu Hwa Lee ),태혜진 ( Hye Jin Tae ),김진옥 ( Jin Ok Kim ),최정임 ( Jeong Im Choi ),김동찬 ( Dong Chan Kim ),손원 ( Won Sohn ),최호순 ( Ho Soon Choi ) 대한내과학회 2012 대한내과학회지 Vol.83 No.6

        Autoimmune pancreatitis (AIP) is type of chronic pancreatitis characterized by an autoimmune inflammatory process. IgG4-positive plasma cells can be found in both the pancreas and at extrapancreatic sites of involvement. A 60-year-old man presented with abdominal discomfort. Computed tomography revealed enlargement of the pancreas and kidneys as well as low-attenuated lesions in both kidneys. MRCP showed narrowing of the distal common bile duct and the proximal pancreatic duct. The serum IgG level was elevated, but IgG4 was normal. Histologic examination revealed lymphoplasma infiltration in the renal tubulointerstitium associated with fibrosis along with many IgG4-positive plasma cells, thereby confirming the diagnosis of tubulointerstitial nephritis-associated AIP. The abnormalities in the clinical, laboratory, and radiological findings improved after oral steroid treatment. This is a case of autoimmune pancreatitis accompanied by tubulointerstitial nephritis diagnosed by renal biopsy. Clinicians should suspect the possibility of extrapancreatic organ involvement in autoimmune pancreatitis, especially when abnormalities in other organs are suggested. Proper examinations must be performed. (Korean J Med 2012;83:775-780)

      • KCI등재

        증례 : 소화기; 십이지장 구부에 발생한 심재성 낭종성 장염에서 지방종을 동반한 1예

        이대성 ( Dae Sung Lee ),정해룡 ( Hae Ryong Jeong ),김진옥 ( Jin Ok Kim ),태혜진 ( Hye Jin Tae ),최호순 ( Ho Soon Choi ),안혜인 ( Hye In Ahn ),백승삼 ( Seung Sam Paik ) 대한내과학회 2014 대한내과학회지 Vol.86 No.3

        Enteritis cystica profunda (ECP) is a very rare hyperplastic benign lesion of the small intestine. Histologically, it is characterized by mucin-filled cystic spaces frequently lined by benign epithelium within the submucosa and muscularis propria. ECP occurs much less frequently than gastritis cystica profunda (GCP) or colitis cystica profunda (CCP). It is most often seen in adults with Crohn`s disease, Peutz-Jeghers syndrome, hamartomatous polyp, or congenital anomalies. We encountered a case of ECP (90 × 15 mm) accompanied by an elongated lipoma in the duodenal bulb, in the absence of any other disease. An endoscopic polypectomy proved sufficient for diagnosing and treating the ECP. To our knowledge, this is the first reported case of ECP accompanied by a lipoma in the duodenal bulb in the absence of any other intestinal disease.

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