말기 위암 환자의 임상적 특성과 예후 인자

김수재,문도호,이춘섭,이정호,김태균,박중철,이지은,Kim, Soo-Jae,Moon, Do-Ho,Lee, Choon-Sub,Lee, Jung-Ho,Kim, Tae-Gyun,Park, Jung-Chul,Lee, Ji-Eun 한국호스피스완화의료학회 2007 한국호스피스.완화의료학회지 Vol.10 No.4

목적: 위암은 각종 암 중에서 발생률, 사망률이 높은 암으로, 이런 말기 위암 환자에 대한 보다 체계적이고 효율적인 호스피스 완화의료를 위한 기초자료를 제공하고자 호스피스 병동에서 임종한 말기 위암 환자의 임상적 특성과 생존기간에 관련된 인자들을 조사하였다. 방법: 2004년 5월 1일부터 2007년 8월 31일까지 일개 종합병원 호스피스 병동에서 말기 위암으로 임종한 99명의 환자를 대상으로 하여 이들의 의무기록을 후향적으로 조사하였다. 수집된 자료는 실수와 백분율, 빈도와 중간 값으로 제시하였으며 호스피스 완화의료 동안의 생존 기간은 SPSS 13.0의 Kaplan-Meier 방법으로 분석하였다. 결과: 99명의 말기 암 환자 중 남자 62명(63%), 여자 37명(37%), 연령의 중간 값은 60.9세이었으며 간 전이가 38명(38%)으로 가장 많았다. 입원 당시 증상은 전신쇠약이 97명(98%), 식욕부진이 85명(86%)이며, 검사실 소견상 저알부민혈증은 87명(88%), 저나트륨혈증이 60명(61%), 빈혈이 72명(73%)에서 있었다. 장폐색이 있었던 환자는 27명(27%)이었으며 이중 완화적 시술을 받은 사람은 17명이었으며 스텐트 삽입법이 11명으로 가장 많았다. 입원 당시 수행능력점수(ECOGPS)가 낮은 경유(P<0.001), 호흡곤란이 있는 경우(P=0.017)에 통계적으로 유의하게 생존기간이 짧은 것으로 나타났다. 호스피스 병동 입원한 기간 중간간은 20일이었고, 전원 시부터 사망하기까지 생존기간의 중간값은 22일이었다. 결론: 보다 더 효율적이고 적절한 호스피스 완화의료를 제공하기 위해서 말기 위암 환자의 생존기간을 예측할 수 있는 인자에 대해 더 많은 표본에서 연구할 필요가 있으며, 이에 대한 지속적 지원이 필요하다고 생각된다. Purpose: The prevalence and mortality of gastric lancer is high. We studied clinical characteristics and prognostic factors of the advanced gastric canter patients who had died in the hospice care unit. and our study is the basic report for efficient hospice and palliative care for the terminally ill patients with gastric cancer. Methods: We retrospectively reviewed the medical records of 99 advanced gastric cancer patients who had died in a hospice rare unit from May 2004 to August 2007. The survival days during the hospice and palliative care were analyzed using Kaplan-Meier method of SPSS version 13.0. Results: There were 62 males (63%) and 37 females (37%). Median age of patients was 60.9 years and liver metastasis was as high as 38 patients (38%) of all. The most prevalent symptom of admission was general weakness (97%) and poor or intake (86%). There were also bypoalbuminemia (88%), anemia (73%), and hyponatremia (61%). Palliative procedure was performed on 17 (63%) out of 27 patients with intestinal obstruction. Of these stents were inserted to 11 patients. The stores of ECOGPS and dyspnea were significantly correlated with the length of survival. The duration of median survival and hospitalization in the hospice and palliative care was 22 days and was 20 days respectively. Conclusion: We need to study more about clinical characteristics of advanced gastric rancor patients to predict the length of survival for an effective hospice and palliative care.

구리(111) 박막에서 관찰되는 낱알 경계와 쌍결정 경계

김수재(Su Jae Kim),김영훈(Young-Hoon Kim),김영민(Young-Min Kim),정세영(Se-Young Jeong) 한국물리학회 2022 새물리 Vol.72 No.11

쌍결정 경계 (twin boundary: TB)는 대부분의 단결정 성장에서 나타나는 결함들 중 하나이다. 일반적으로 TB를 대칭성을 만족하는 낱알 경계 (grain boundary: GB) 중 하나라고 정의하기도 하지만 그 특성과 형성 메커니즘은 GB와 매우 다르다. 덩어리 결정 (bulk crystal) 에서 TB는 강탄성 구역 (ferroelastic domain) 의 형성과 유사하다. 덩어리 결정에서 TB는 고온상에서 저온상으로 상전이할 때 구조적으로 발생하는 변형을 완화하기 위해 나타난다. 그러나 박막에서는 성장 초기에 서로 다른 층쌓기를 갖는 나노결정들이 성장하고 만나면서 경계를 형성한다. 10<SUP>12</SUP>개가 되는 핵들이 모두 한방향을 갖는 것을 기대할 수는 없기 때문에 TB의 형성은 불가피하다. 그러나 GB는 노력에 의해 기술적으로 완전히 제거할 수 있다. 형성된 나노결정들의 배향 (orientation)이 불규칙하고 임의의 방향을 향해 있으면 이들이 성장하면서 서로 닿았을 때 GB가 형성되므로 초기 두 다른 층쌓기를 갖는 나노결정들이 일관성있게 동일면에서 만나도록 층쌓기를 제어하여 TB만 형성되도록 유도하면 물질의 물성도 향상시킬 수 있고 박막의 표면도 평탄하게 성장할 수 있다. Twin boundaries (TBs) are one of the defects that form in most single-crystal growth. Although they are usually considered as one of the grain boundaries (GBs) that satisfy a symmetry operation, the properties and formation mechanism of TBs are very different from those of GBs. In particular, in bulk crystals, TBs are usually analogous to ferroelastic domains. TBs are formed to relieve structurally occurring strain when a phase transitions from a high-temperature phase to a low-temperature phase. They are formed in thin films when two islands with different stacking orders at nucleation meet. At this point, TBs are formed when single-crystal islands meet coherently with a coplanar layer. By contrast, GBs are formed when arbitrarily oriented islands meet incoherently. The effects of TBs and GBs on physical properties are greatly different.

Expression and introduction of C4 photosynthesis genes into rise(Oryza sativa L.)

김수재 ( Kim Su Jae ) 강원대학교 농업생명과학연구원 2003 강원 농업생명환경연구 Vol.14 No.-

LoRa 네트워크를 사용한 위치 기반 스마트 구명조끼 시스템

김수재(Soo-Jae Kim),장우석(Woo-Seok Jang),권익주(Ik-Joo Kwon),김성민(Seong-Min Kim),황윤성(Yoon-Seong Hwang),오병우(Byoung-Woo Oh) 한국정보기술학회 2021 Proceedings of KIIT Conference Vol.2021 No.6

기존의 수상 안전 시스템에서는 GPS 기술을 활용해 현재 위치 정보를 보내는 기능만을 제공했다. 본 논문에서는 GPS 기술을 포함한 심박 센서, 온도 센서 그리고 가속도 센서 등을 활용해 근해, 수상 레저스포츠 사업장 등의 안전관리센터에서 착용자의 위급 상황 발생을 능동적으로 감지하고, 실시간으로 착용자의 상태를 확인할 수 있도록 하여 더 효율적이고 신속한 구조를 돕는 레저 가디언 시스템을 제안한다. In the existing water safety system, only the function of sending current location information was provided using GPS technology. In this paper, by using heart rate sensor, temperature sensor, and acceleration sensor including GPS technology, it is possible to actively detect the occurrence of an emergency situation of the wearer in safety management centers such as offshore and water leisure sports area, and to check the wearer"s condition in real time. We propose a Leisure Guardian system that helps the rescue more efficiently and quickly.

MED 담수기내 수평관외 강하막증발기의 성능해석

김수재(Soo Jae kim),제준호(Junho Je),김무환(Moo Hwan kim) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.11

In this study, 3D numerical analysis of the performance of falling film evaporator in Multi effect distillation (MED) plant is carried out by using fluent 6.3 and UDF. To investigate thermal performance within different operating conditions, inlet vapor mass flux used in this study are 0.5~2.5㎏/㎡s,inlet non condensable gas mass fraction is varied from 0 to 1%, and falling liquid film Reynolds number is varied from 100 to 1000.As inlet vapor mass flux increase the performance is barely changed and then decreased. As falling film liquid Reynolds number increases, the performance is also increased, however it’s increasing ratio decreases as it grows. 1% non condensable gas inner tubes can make the performance decrease by 0.87%.

MED 담수기내 수평관 강하막식 증발기의 3D 수치해석적 연구

김수재(Soo Jae Kim),제준호(Junho Je),김무환(Moo Hwan Kim) 대한기계학회 2013 大韓機械學會論文集B Vol.37 No.5

본 연구에서는 다중효용 증발식 담수기에 쓰이는 강하막식 증발기의 수치해석을 수행하였다. 증발기에 사용되는 다관군을 다공성 매질로 묘사하고 공간평균 개념을 적용하였다. 증발기 내부의 유동계산 및 열 전달로 인한 상변화를 계산하기 위해서 FLUENT 와 UDF 가 사용되었다. 작동조건에 대한 증발기의 성능변화를 살펴보기 위해 수평관 내 증기 질량 유속을 0.5~2.5kg/㎡s, 관내입구 측 비 응축성 기체의 질량분율을 0~1%, 그리고 수평관 외 뿌려지는 강하막의 액막 레이놀즈 수를 100~1000 으로 바꾸어가며 해석을 수행하였다. 관내 증기유속 및 관외 강하막 레이놀즈 수가 증가할수록 증발량은 증가하였으며, 관내 비 응축성 기체의 질량분율이 1%증가함에 따라 증발량이 0.87%줄어들었다. In the present work, a numerical study of a horizontal falling film evaporator in a multi-effect distillation (MED) plant is performed. Tube bundles in the evaporator are described as porous media, and a volume-averaged method is applied. To calculate the fluid flow and phase change in the evaporator due to heat transfer in the system, FLUENT and user-defined functions (UDF) are used. To observe the performance of the evaporator under different operational conditions, tests are conducted for a steam mass flux ranging from 0.5 to 2.5 kg/㎡s in the horizontal tube, for mass fraction of the noncondensable gas in the tube inlet ranging from 0% to 1%, and for film Reynolds numbers ranging from 100 to 1,000 for the falling film. The evaporation rate increases with the steam mass flux and Reynolds number. In contrast, the evaporation rate decreases by 0.87% with a 1% increase in the mass fraction of the noncondensable gas in the tube.

Salmonella gallinarum 분리주로부터 추출한 세포외막 단백질의 닭에 대한 면역원성

이희수,김수재,김기석,모인필,우용구,권용국,김태종,Lee, Hee-soo,Kim, Soon-jae,Kim, Ki-seuk,Mo, In-pil,Woo, Yong-ku,Kwon, Yong-kuk,Kim, Tae-jong 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.3

Fowl typhoid caused by Salmonella gallinarum has increased dramatically since 1992 and has caused a great economic losses in chicken industry by characterizing with high mortality. In these studies, we investigated the immunogenicity and protectivity in chickens which were immunized with outer membrane protein(OMP) extracted from isolates of S gallinarum against challenge with live microorganism. Outer membrane proteins were composed of various sizes of molecular weight including 14K, 22K, 31K, 36K, 40K and 55K and the most of them responded strongly against rabbit antisera in immunoblot analysis. The chickens vaccinated with OMP or vaccinated with whole-cell combined with OMP($200{\mu}g$/chickens) complex showed higher delayed type hypersensitivity(DTH) response than that of whole-cell vaccinated group. The protective rates of OMP or whole-cell combined with OMP complex group against challenge of S gallinarum were higher (above 75%) than those (45~50%) of whole-cell vaccinated group. All vaccines were safe and the body weight-gains of all vaccinated groups were not significantly different (p<0.05) from those of nonvaccinated control group. In vitro tests, OMP stimulated both the proliferation of lymphocytes and T-lymphocytes, and OMP-induced lymphocyte proliferation was higher in the cells of the immunized chickens with OMP than in those from the control chickens.

공유PM 서비스를 고려한 수단선택모형 추정에 관한 연구 - 접근통행과 생활권통행을 중심으로 -

김지윤(Kim, Ji Yoon),김수재(Kim, Su Jae),이경재(Yi, Gyung Jae),추상호(Choo, Sang Ho) 대한토목학회 2020 대한토목학회 학술대회 Vol.2020 No.10

Comparison of the Structural, Magnetic, Electronic, and Optical Properties for ZnCoO and Co-precipitation Samples

김성진,조용찬,김수재,이승훈,정세영,배종성,정일경,Won-Kyung Kim,조채용,박성균 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4

In order to investigate the ferromagnetism of Co-doped ZnO, we systematically fabricated Zn1−xCoxO (x = 0, 0.05, 0.1, 0.2, 0.4) thin films on (0001) Al2O3 substrates by rf-sputtering and measured their structural, electronic, optical, and magnetic properties. Below 20 mol% of Co, the Co ion could be successfully substituted at Zn site and showed clear paramagnetism in superconducting quantum interference devices (SQUID) and magnetic circular dichroism (MCD)measurements. However, secondary phases, including Co metal clustering, were found in the ZnO matrix at a 40-mol% Co concentration, showing a strong ferromagnetism due to the contributes of microscopic precipitates of Co ions. Consequently, the clear paramagnetic behaviors of all the fabricated ZnCoO thin films in the magneto-optic MCD results revealed that the spin-polarized band structure, an intrinsic property of ferromagnetism diluted ferromagnetic semiconductors (DMSs),could not be induced by the substituted Co ions themselves. Importantly, these results indicate that any intrinsic ferromagnetism in ZnCoO cannot be induced without the contribution of hydrogen.

마이크로 채널을 포함한 마이크로 구조물의 복합 열전달에서 전도 영향에 대한 수치적 연구

최치웅(ChiWoong Choi),김수재(Soojae Kim),김무환(MooHwan Kim) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.11

In this study, three dimensional numerical analysis of conjugate heat transfer in single rectangular microchannel with different conductivities was carried out using FLUENT 6.3 with UDF (user defined function) of natural convection. Conductivities used in this study were 8, 0.8, 0.08, and 0.008. Heat flux was 200 ㎾/㎥ and mass fluxes were 50 ? 400 ㎏/㎡s. Heat loss was evaluated and heat loss evaluation method was verified. The heat loss evaluation method was applicable in microchannel with lower conductivity. However, higher conductive microchannel has different heat distribution. Therefore, the heat loss evaluation method was modified with different conductivity. The heat flow distribution was analyzed and effective area coefficient was proposed to represent heat flow in rectangular microchannel. As the conductivity of microchannel decreased, the heat flow through another walls except heating wall increased.