황금이 A549 세포주에서 $TNF-{\alpha}$ 및 IL-4로 유도된 chemokines에 미치는 영향

김성호,김희택,Kim, Sung-Ho,Kim, Hee-Taek 대한한방안이비인후피부과학회 2007 한방안이비인후피부과학회지 Vol.20 No.2

Objectives : In the present study, the effect of Scutellariae radix on the release of RANTES, eotaxin, TARC induced by $TNF-{\alpha}$ and IL-4 in human bronchial epithelial cell(A549 cell) was examined. Scutellariae radix significantly inhibited the secretion of RANTES, eotaxin, TARC with a dose-dependant manner. Methods : In the experiment, to observe the toxity of the cell according to concentration of Scutellariae radix, MIT assay was carried out to examine cell viability. The effective dosage did not have the cytotoxicity on human bronchial epithelial cell in all control group excepting 50\;{\mu}g/ml$ concentration. Results : The above results shows Scutellariae radix inhibits the secretion of the release of RANTES, eotaxin, TARC on human bronchial epithelial cell(A549 cell). Conclusion : These results suggest that Scutellariae radix could be used as a prophylaxis and remedy of asthma induced by allergy and inflammatory reaction caused by several reasons.

The New Calculation Model of Film Thickness to Evaluat Asphalt Mixtures

김성호,김부일,Kim, Sung-Ho,Kim, Boo-Il Korean Society of Road Engineers 2007 한국도로학회논문집 Vol.9 No.1

최근 아스팔트 혼합물의 VMA 혹은 그 외 다른 체적요소의 기준값을 대체하기 위해 유효아스팔트 함량(film thickness)에 대해 논의되어 왔다. 이들 중 일부는 유효 아스팔트 함량의 기준값을 제안하였으며, 일부는 새로운 개념 또는 계산 방법을 포함하는 새로운 모델을 즉, 인덱스 모델(index model) 또는 가상 모델(virtual model)을 소개하였다. 각각의 모델은 아스팔트혼합물의 체적특성을 설명하는데 있어서 형상, 크기 등 골재의 체적특성을 정량화하는 방법을 이용한다. 본 연구에서는 인덱스 모델과 가상 모델의 장점을 결합한 개선된 가상 모델 (modified virtual model)을 제안하였다. 개선된 가상 모델을 기존의 두 가지 모델과 비교평가하기 위하여 DASR 개념에 근거하여 제작된 총 8개의 혼합물을 대상으로 IDT 시험과 APA 시험을 수행하였다. 시험 결과, 아스팔트 혼합물의 공용성과 유효 아스팔트 함량의 관계를 계산함에 있어서 본 연구에서 제안된 가상 모델은 기존의 모델들에 비해 더 적절함을 알 수 있었다. Many researches have recently discussed about the film thickness as a good substitute or supplement for VMA or other volumetric criteria in the design procedure. Some researchers have not only proposed the specific number for the recommended film thickness, but also introduced the new calculation procedures or concepts. Each model (index model and the virtual model) has its own advantages and disadvantages in terms of the ability to account for the volumetric properties of the mixture. In this paper, the modified virtual model was proposed to combine advantages from both models. However, it cannot be disregarded the way to determine the appropriate particle shape factors for different sources and sizes of aggregates. In order to evaluate the different calculation methods, mixtures with two aggregate sources and eight gradations were designed based on the dominant aggregate size range (DASR) porosity concept. Superpave indirect tensile test (IDT) and asphalt pavement analyzer (AEA) test were used to describe the performance of mixtures. Test results indicated that the virtual model, which is the same to the modified virtual model for sphere 1:1 case, is better than the conventional standard model to define the range of the film thickness to have better performance of asphalt mixtures.

NED를 사용하는 FH-CSS(Frequency Hopped - Chirp Spread Spectrum)의 항 재밍 성능 분석

김성호,김영재,황석구,조병각,신관호,김남,Kim, Sung-Ho,Kim, Young-Jae,Hwang, Seok-Gu,Jo, Byoung-Gak,Shin, Kwan-Ho,Kim, Nam 한국군사과학기술학회 2011 한국군사과학기술학회지 Vol.14 No.1

In the defence wireless communications, conventional Anti-Jamming techniques(Frequency Hopping/Spread Spectrum or Direct Sequence/Spread Spectrum) are used to overcome a intentional interfering signals which are single/multitone or partial band jammer etc. DS/SS techniques is very strong on tone jamming signal but not to be on a partial band jammer. So FH/SS AJ performances are expected method of an substitution of DS/SS, however FH/SS could not have good performance on some BMTJ(Band Multi-tone Jammer). So this paper proposes FH-CSS (Frequency Hopped - Chirp Spread Spectrum) to get more robustness against jammers(BMTJ, PBNJ) and analyze the AJ performances.

심부 혈전 증의 외과적 혈전제거술

김성호,이상호,Kim, Seong-Ho,Lee, Sang-Ho 대한흉부심장혈관외과학회 1991 Journal of Chest Surgery (J Chest Surg) Vol.24 No.12

From July 1988 to January 1991 six patients, aged 29 to 70 years underwent transfemoral thrombectomy for the treatment of deep vein thrombosis. Preoperative venograms showed thrombi in the following locations: calf veins[five], superficial femoral or popliteal veins [four], common femoral veins[three], and iliac veins[three], Durations of symptoms before admission were from 1 day to 20days. Operations were performed under local anesthesia and all the patients were requested for doing Valsalva maneuver during thrombectomies. All patients were received heparin pre-and postoperatively, which was switched to Coumadin for preventing of rethrombosis. One patient was transferred to other hospital 4 months after operation due to regional reason, and the remained five patients were evaluated with a mean follow-up time of 20 months. There was no evidence of postoperative pulmonary embolism. Three of five patients were clinically asymptomatic. One complained of the heaviness of involved leg in the evening, and the other had discomfort on walking Even though our cases were a few in number, we concluded that thrombectomy is a valuable treatment modality of deep vein thrombosis.

기존 학교건물 골조와 내진보강요소 일체화를 위한 변형경화형 시멘트 복합체를 적용한 스터드 전단 접합부의 구조성능

김성호,윤현도,Kim, Sung-Ho,Yun, Hyun-Do 한국교육시설학회 2013 敎育施設 Vol.20 No.4

Some results of experimental investigation conducted to assess the effect of cement composite strength and ductility on the shear behavior and crack-damage mitigation of stud connections between existing reinforced concrete frame in school buildings and seismic strengthening elements from cyclically direct shear tests are described. The cement composite strengths include 50 for medium strength and 70 MPa for high strength. Two types of cement composites, strain-hardening cement composite (SHCC) and non-shrinkage mortar, are used for stud shear connection specimens. The special SHCCs are reinforced with hybrid 0.2% polyethylene (PE) and 1.3% polyvinyl alcohol (PVA) fibers at the volume fraction and exhibits tensile strain capacity ranging from 0.2 to 0.5%. Test result indicates that SHCC improves the seismic performance and crack-damage mitigation of stud shear connections compared with stud connections with non-shrinkage mortar. However, the performance enhancement in SHCC stud connections with transverse and longitudinal reinforcements is less notable for those without additional reinforcement.

기존 철근콘크리트 건물과 내진보강요소의 접합부 충진을 위한 뿜칠형 섬유보강 시멘트 복합체(SHCC)의 개발

김성호,윤길호,김용철,김재환,윤현도,Kim, Sung-Ho,Youn, Gil-Ho,Kim, Yong-Cheol,Kim, Jae-Hwan,Yun, Hyun-Do 한국교육시설학회 2012 敎育施設 Vol.19 No.5

The goals of this study are to develop a sprayable strain-hardening cement composite (SHCC) and to investigate the potential of the sprayable SHCC for packing the joint between existing R/C building and seismic retrofit elements. This paper provides the procedure for the development of a sprayable SHCC, test results of fresh properties required to a sprayable SHCC, and mock-up test results of developed sprayable SHCC. Control mixture of polyvinyl alcohol (PVA) fiber-reinforced SHCC (PVA-SHCC) was predetermined based on available research results. The pumpability and sprayability of the SHCC mixture were depended on the fluid property of fresh SHCC mixture. In this study, the effects of admixtures such as AE agent and fly ash on the rheological and rebound properties of control SHCC mixture were investigated to determine a sprayable SHCC mixture. Flow values and air content during shotcreting procedure of sprayable SHCC were also evaluated. The results show that flow or flowability and amount of air of three SHCC mixtures decreased almost linearly according to shotcreting procedure from mixer to nozzle. And the pumpability and sprayability of mixture with AE agent and low amounts of fly ash were superior to the those of SHCC. Mock-up test result show that developed sprayable SHCC indicates much improved workability and shotcrete construction period than conventional method(nonshrinkage mortar).

얼굴 표정공간에서 최적의 표정전이경로 자동 설정 방법

김성호,Kim, Sung-Ho 한국정보처리학회 2007 정보처리학회논문지 A Vol.14 No.2

본 논문은 애니메이터로 하여금 표정공간으로부터 임의의 표정상태 수 개를 선택하도록 하면, 최적의 표정전이경로를 자동적으로 설정하도록 해줌으로써, 얼굴 표정 애니메이션을 실시간적으로 생성하거나 표정 제어가 가능하도록 하기 위한 기법을 기술한다. 표정공간은 약 2500개의 얼굴 표정상태 간의 거리를 구하고, 다차원 스케일링 기법을 사용하여 2차원 평면에 분포시킴으로서 형성된다. 표정공간에서 최적의 표정전이경로를 설정하기 위해서는 임의의 얼굴 표정상태를 기준으로 사분면처럼 4개의 영역으로 나눈다. 그리고 각 영역별로 최단거리에 존재하는 열굴 표정상태를 결정하고, 그 중에서 가장 가까운 얼굴 표정상태를 선택하여 전이시키고, 전이가 끊어진 얼굴 표정상태에서는 두 번째, 세 번째 혹은 네 번째로 가까운 얼굴 표정상태를 선택하여 순서대로 전이시킴으로써 완전한 표정전이경로가 결정된다. 그리고 애니메이터가 표정공간에서 대표적인 수 개의 표정상태만을 선택해주면 시스템은 자동적으로 최적의 표정전이경로를 설정하여 준다. 본 논문은 애니메이터들로 하여금 본 시스템을 사용하여 얼굴 애니메이션을 생성하거나 표정 제어를 수행하도록 하였으며, 그 결과를 평가한다. This paper presents a facial animation and expression control method that enables the animator to select any facial frames from the facial expression space, whose expression transfer paths the system can setup automatically. Our system creates the facial expression space from approximately 2500 captured facial frames. To create the facial expression space, we get distance between pairs of feature points on the face and visualize the space of expressions in 2D space by using the Multidimensional scaling(MDS). To setup most suitable expression transfer paths, we classify the facial expression space into four field on the basis of any facial expression state. And the system determine the state of expression in the shortest distance from every field, then the system transfer from the state of any expression to the nearest state of expression among thats. To complete setup, our system continue transfer by find second, third, or fourth near state of expression until finish. If the animator selects any key frames from facial expression space, our system setup expression transfer paths automatically. We let animators use the system to create example animations or to control facial expression, and evaluate the system based on the results.

브레이스 및 전단벽 보강에 따른 철근콘트리트 건축물의 내진성능평가

김성호,류승현,송영재,김용철,윤현도 한국구조물진단유지관리학회 2011 한국구조물진단학회 학술발표회논문집 Vol.2011 No.9

Significant numbers of earthquakes have been increased steadily in Korea. As earthquakes occur frequently, there is growing concern about earthquake damage. Especially, RC school buildings without seismic-design are vulnerable to earthquakes. In this study, seismic performance of RC school building according to seismic-retrofit was evaluated for the reduction of earthquake damage. The seismic index and the seismic performance of the building were evaluated through the Japanese standard and nonlinear analysis program, Midas Gen. The analytical results demonstrated that seismic-strengthening of the school building has more than 90% of enhancement in the shear resistance.

모션 데이터를 이용한 3차원 아바타 얼굴 표정 제어

김성호,정문렬,Kim Sung-Ho,Jung Moon-Ryul 한국정보처리학회 2004 정보처리학회논문지 A Vol.11 No.5

본 논문은 사용자로 하여금 얼굴표정들의 공간으로부터 일련의 표정을 실시간 적으로 선택하게 함으로써 3차원 아바타의 얼굴 표정을 제어하는 기법을 제안하고, 해당 시스템을 구축한다. 본 시스템에서는 얼굴 모션 캡쳐 데이터로 구성된 2400여개의 표정 프레임을 이용하여 표정공간을 구성하였다. 본 기법에서는 한 표정을 표시하는 상태표현으로 얼굴특징 점들 간의 상호거리를 표시하는 거리행렬을 사용한다. 이 거리행렬의 집합을 표정공간으로 한다. 그러나 이 표정공간은 한 표정에서 다른 표정까지 이동할 때 두 표정간의 직선경로를 통해 이동할 수 있는 그런 공간이 아니다. 본 기법에서는 이 경로를 표정 데이터로부터 근사적으로 유추한다. 우선, 각 표정상태를 표현하는 거리행렬간의 거리가 일정 값 이하인 경우 두 표정을 인접해 있다고 간주한다. 임의의 두 표정 상태가 일련의 인접표정들의 집합으로 연결되어 있으면 두 표정간에 경로가 존재한다고 간주한다. 한 표정에서 다른 표정으로 변화할 때 두 표정간의 최단경로를 통해 이동한다고 가정한다. 두 표정간의 최단거리를 구하기 위해 다이내믹 프로그래밍 기법을 이용한다. 이 거리행렬의 집합인 표정공간은 다차원 공간이다. 3차원 아바타의 얼굴 표정은 사용자가 표정공간을 항해하면서 원하는 표정을 실시간 적으로 선택함으로써 제어한다. 이를 도와주기 위해 표정공간을 다차원 스케일링 기법을 이용하여 2차원 공간으로 가시화 했다. 본 시스템이 어떤 효과가 있는지를 알기 위해 사용자들로 하여금 본 시스템을 사용하여 3차원 아바타의 얼굴 표정을 제어하게 해본 결과, 3차원 아바타의 실시간 얼굴 표정 제어가 필요한 각 분야에서 매우 유용하게 사용될 것으로 판단되었다.24시간 경과시킨 후 치아의 장축에 따라 절단하여 침투된 색소의 정도를 광학현미경상에서 40배로 관찰하였다. 각각의 실험결과는 ANOVA/Tukey's test 및 Kruskal-Wallis non-parametric independent analysis와 Mann-Whitney U test에 의하여 통계 분석하여 다음과 같은 결론을 얻었다. 1. 대조군에 있어서 혼합형 복합레진의 미세인장 결합강도는 미세혼합형에 비하여 높았으며, 실험군 사이에는 유의차를 보이지 않았다. 2.모든 복합레진의 미세인장 결합강도는 와동의 C-factor증가에 따라 감소하는 경향을 나타내었고, 혼합형 복합레진의 실험군은 대조군에 비하여 낮게 나타났으며, 미세혼합형 복합레진에서는 유의차를 보이지 않았다. 3. 절단측 및 치은측 변연부의 미세누출정도는 혼합형 복합레진이 미세혼합형에 비하여 대체로 높게 나타났다. 4. 모든 실험군에서 미세누출은 C-factor증가에 따라 증가하였고 절단측에 비하여 치은측 변연이 높게 나타났으나 통계학적 유의차는 보이지 않았다. C-factor의 변화에 대하여 필러함량과 탄성계수가 높은 혼합형 복합레진이 미세혼합형에 비하여 더 민감한 결과를 보인다. 이는 복합레진 수복시 재료의 선택과 중합수축의 적절한 조절이 중요한 요소임을 시사한다.s에서는 1주, 2주에서 강한 염증반응을 보였으나 12주에서는 염증반응이 감소하였다. 4) 새로 개발된 봉함제 Adseal-1,2는 1주, 2주에서는 가장 약한 염증반응을 보이나 4주, 12주 후에는 AH Plus와 비슷한 수준의 염증 반응을 보였다. 5) Pulp Canal Sealer를 제외한 모든 군에서 인정할 만한 생체친화성을 보였다. 6) This paper propose a method that controls facial expression of 3D avatar by having the user select a sequence of facial expressions in the space of facial expressions. And we setup its system. The space of expression is created from about 2400 frames consist of motion captured data of facial expressions. To represent the state of each expression, we use the distance matrix that represents the distances between pairs of feature points on the face. The set of distance matrices is used as the space of expressions. But this space is not such a space where one state can go to another state via the straight trajectory between them. We derive trajectories between two states from the captured set of expressions in an approximate manner. First, two states are regarded adjacent if the distance between their distance matrices is below a given threshold. Any two states are considered to have a trajectory between them If there is a sequence of adjacent states between them. It is assumed . that one states goes to another state via the shortest trajectory between them. The shortest trajectories are found by dynamic programming. The space of facial expressions, as the set of distance matrices, is multidimensional. Facial expression of 3D avatar Is controled in real time as the user navigates the space. To help this process, we visualized the space of expressions in 2D space by using the multidimensional scaling(MDS). To see how effective this system is, we had users control facial expressions of 3D avatar by using the system. As a result of that, users estimate that system is very useful to control facial expression of 3D avatar in real-time.

계지작약지모탕(桂枝芍藥知母湯)이 DNCB로 유발된 알레르기성 접촉피부염에 미치는 영향

김성호,김희택,Kim, Sung-Ho,Kim, Hee-Taek 대한한방안이비인후피부과학회 2010 한방안이비인후피부과학회지 Vol.23 No.1

Objectives : The purpose of this study is to investigate the effects of Gyejijakyakjimo-Tang on the Allergic Contact Dermatitis caused by 2,4-dinitro-chlorobezene(DNCB). Methods : Twenty eight mice were divided into four groups ; normal, control, experimental group A and B. Control and experimental groups were induced allergic contact dermatitis by DNCB. Experimental group A was orally administered the Gyejijakyakjimo-Tang and experimental group B was orally administered the prednisolone. In this study, ear thickness measurement, auricle microphotograph observation, MPO(Myeloperoxidase) activity measurement, Reverse transcription-polymerase chain reaction(RT-PCR) analysis of the mRNA level of TNF-$\alpha$, IL-$1{\beta}$ were performed on these four groups. In addition, the effect of Gyejijakyakjimo-Tang on cell viability and the effect of Gyejijakyakjimo-Tang on the compound 48/80-induced histamine release from HMC and RPMC were measured. Results: 1. Both experimental group A and B had decreased ear thickness compared with control group In contact hypersensitivity assay. 2. In experimental group A, inflammatory edema was similarly observed comparing to control group. Nevertheless, inflammatory edema was obviously reduced in experimental group B. In both experimental group A and B, pathological lesion of dermatitis were alleviated. In addition, the numbers of infiltrated inflammatory cells were decreased compared with control group. 3. Compared to the normal group, there was a noticeable increase in MPO activity in control group. However, in experimental group A and B, it showed remarkable inhibition of the increase in MPO activity comparing with control group. 4. The level of expression of TNF-$\alpha$, IL-$1{\beta}$ in experimental group A and B were meaningfully lower than those in control group. 5. In MTT assay, the concentrations of Gyejijakyakjimo-Tang that were used on the test had no cytotoxicity. 6. Gyejijakyakjimo-Tang dose-dependently inhibited the compound 48/80-induced histamine release from both HMC and RPMC. Conclusions : According to above experiments, Gyejijakyakjimo-Tang was effective on allergic contact dermatitis.