초분광 반사광 영상을 이용한 방울토마토 내부품질 인자 예측

김대용 ( Dae Yong Kim ),조병관 ( Byoung Kwan Cho ),김영식 ( Young Sik Kim ) 한국산업식품공학회 2011 산업 식품공학 Vol.15 No.4

Hyperspectral reflectance imaging technology was used to predict internal quality of cherry tomatoes with the spectral range of 400-1000 nm. Partial least square (PLS) regression method was used to predict firmness, sugar content, and acid content. The PLS models were developed with several preprocessing methods, such as normalization, standard normal variate (SNV), multiplicative scatter correction (MSC), and derivative of Savitzky Golay. The performance of the prediction models were investigated to find the best combination of the preprocessing and PLS models. The coefficients of determination ( ) and standard errors of prediction (SEP) for the prediction of firmness, sugar content, and acid content of cherry tomatoes from green to red ripening stages were 0.876 and 1.875 kgf with mean of normalization, 0.823 and 0.388oBx with maximum of normalization, and 0.620 and 0.208% with maximum of normalization, respectively.

뇌하수체 선종과 동반된 갑상선호르몬 저항성 증후군 1예

김대용 ( Dae Yong Kim ),김영묵 ( Young Mook Kim ),최현희 ( Hyun Hee Choi ),이주용 ( Joo Yong Lee ),한재필 ( Jae Pil Han ),이성진 ( Seong Jin Lee ),최문기 ( Moon Gi Choi ) 대한내과학회 2008 대한내과학회지 Vol.74 No.1

저자들은 갑상선자극호르몬분비호르몬 자극검사, 갑상선자극호르몬 α-아단위 측정, 뇌하수체 자기공명영상, 갑상선호르몬 수용체 β 유전자 검사로 진단한 비기능성 뇌하수체미세선종과 동반된 뇌하수체성 갑상선호르몬 저항성 증후군 증례를 국내에서 처음으로 경험하였기에 문헌고찰과 함께 보고하는 바이다. Resistance to thyroid hormone (RTH) is an autosomal dominant disorder that`s characterized by inappropriate normal or elevated TSH levels despite of the elevated thyroid hormone levels. RTH is distinguished from the TSH secreting pituitary adenoma by performing the TRH stimulation test, TSH alpha-subunit measurement and sellar MRI. A 23-year old woman visited our hospital complaining of fatigue, palpitation and heat intolerance and she had an anterior neck mass. She had elevated total T3, free T4 and TSH levels. The serum TSH levels were increased during the TRH stimulation test before and after T3 suppression. The serum TSH alpha-subunit showed a normal response and the serum TSH alpha-subunit/TSH molar ratio did not increase over 1.0 with TRH stimulation. Thyroid hormone receptor β gene mutation was identified. Although a left pituitary microadenoma was revealed on sellar MRI, the patient was diagnosed as having pituitary RTH with a nonfunctioning pituitary microadenoma. We report here on a patient with pituitary RTH and a nonfunctioning pituitary microadenoma, and this is the first such case in Korea.

브로콜리 추출물의 향장활성 효과

김대용ㆍ조석철ㆍ권혁선ㆍ김미경(Dae Young KimㆍSeok chul ChoㆍHyuk sun KwonㆍMee Kyung Kim) 한국인체미용예술학회 2016 한국인체미용예술학회지 Vol.17 No.1

In this study, we investigated the anti-oxidative effects, antimicrobial, and anti-inflammatory activities of the extracts from broccoli to evaluate its use as a functional ingredient in cosmetics. The extracts are WE (water extract at RT), MWE (mineral water extract at RT), EE (70% ethanol extract at RT), and USEE (heat process for 12 hours at 60℃ after ultrasonification for six hours with 70% ethanol). The measurements of the total polyphenol content from broccoli extracts were highest in EE at 425.24±13.9 mg/g dry. The result of electron donating ability of EE was the highest at 10,000 ㎍/㎖ as 97.81% and increased in a concentration-dependent manner. The ferric reducing antioxidant powder (FRAP) of EE was the highest at 10,000 ㎍/㎖ as 1235.6 μM. In an antimicrobial activity test, the EE showed significant antimicrobial activity against S. epidermidis, S. aureus, E. coli, P. acnes, and P. ovale. Furthermore, broccoli extract exhibited no cytotoxicity in RAW 264.7 cells. Also anti- inflammatory activity by NO assay showed LPS-induced NO was significantly inhibited following treatment with EE of 1,000 ㎍/㎖. Therefore, the broccoli ethanol extract can be used as a resource of natural cosmetic material for functional cosmetics.

도심 고가도로 교각부의 야간조명연출디자인에 관한 연구

김대용(Kim Dae-Yong),최병욱(Choi Beyung-Woook),고영준(Ko Young-Jun),이영창(Lee Young-Chang) 한국디자인학회 2007 한국디자인학회 학술발표대회 논문집 Vol.- No.-

피부미용소재로서 보리순 추출물의 생리활성 특성 연구

김대용(Dae Young Kim),김미경(Mee Kyung Kim) 한국인체미용예술학회 2016 한국인체미용예술학회지 Vol.17 No.4

This study investigated the anti-oxidative effects, antimicrobial, and anti-inflammatory activities of barley sprout extracts by extraction processes to evaluate its use as a functional raw material for beauty products. The extracts are water extraction (WE) at 100℃, ethanol extraction (EE) at room temperature, ultrasonification for 6 h with ethanol solution and then extraction for 12 h at 60℃ (USEE) and high pressure extraction for 9 min and then extraction for 12 h at 60℃ with ethanol solution (HPEE). The result of the 2,2‘-azinobis[3-ethylbenzothiazoline-6- sulfonic acid] (ABTS) radical scavenging activity of all extracts was highest at 5,000 μg/mL as 97.9~99.85% and was significantly increased in a concentration-dependent manner. In an antimicrobial activity test, the USEE showed relatively high antimicrobial activity against S. epidermidis, S. aureus, E. coli and P. acnes. Furthermore, barley sprout extracts exhibited no cytotoxicity in RAW 264.7 cells. Also anti-inflammatory activity by nitric oxide (NO) assay showed lipopolysacchride (LPS)-induced NO was significantly inhibited following treatment with USEE of 100 μg/mL, and the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins were significantly inhibited following treatment with EE, USEE and HPEE of 100 μg/mL. Accordingly, it can be concluded that barley sprout USEE has the potential to be used as a functional beauty and cosmetic material.

중장비용 우레탄 도료 내후성 가속시험

김대용(Dae Yong Kim),김영준(Young Jun Kim) 한국신뢰성학회 2001 신뢰성응용연구 Vol.1 No.2

칼라영상을 이용한 방울토마토 품질 인자 계측에 관한 연구

김대용(Dae-Yong Kim),오현근(Hyun-Keun Oh),이남근(Nam-Keun Lee),김영식(Young-Sik Kim),조병관(Byung-Kwan Cho) 충남대학교 농업과학연구소 2010 농업과학연구 Vol.37 No.2

Surface color is the most important quality factor for the grade evaluation of cherry tomato. Color is one of the representative indicators for the maturity which is closely related to the internal quality of cherry tomato, such as firmness, sugar content, and acidity. This study was carried out to investigate the relationship between surface color and internal quality of cherry tomatoes harvested from both hydroponic and soil culture at different ripening stages . To calculate the color values of cherry tomatoes an automatic color imaging system was constructed. A specially designed image processing algorithm for the color measurement was developed. The color values of L*, a*, b* were calculated from the initial color values of RGB and then compared with the internal quality. Statistical analyses indicated that the internal quality was more highly correlated with the surface color than size of cherry tomatoes. Color image features were also investigated to detect external damage of cherry tomatoes. The value of (R value - R mean value)/R mean value was the most effective image feature for the detection of damaged areas on the surface of cherry tomatoes. The results of this study demonstrated the feasibility of color sorting process as an alternative of the conventional drum type size sorting system for cherry tomato industry.

초분광 영상을 이용한 송이토마토의 비파괴 품질 예측

김대용(Dae-Yong Kim),조병관(Byoung-Kwan Cho),김영식(Young-Sik Kim) 충남대학교 농업과학연구소 2012 농업과학연구 Vol.39 No.3

Spectroscopic measurement method based on visible and near-infrared wavelengths was prominent technology for rapid and non-destructive evaluation of internal quality of fruits. Reflectance measurement was performed to evaluate firmness, soluble solid content, and acid content of truss tomatoes by hyperspectral reflectance imaging system. The Vis/NIR reflectance spectra was acquired from truss tomatoes sorted by 6 ripening stages. The multivariable analysis based on partial least square (PLS) was used to develop regression models with several preporcessing methods, such as smoothing, normalization, multiplicative scatter correction (MSC), and standard normal variate (SNV). The best model was selected in terms of coefficient of determination of calibration (R²c) and full cross validation (R²cv), and root mean standard error of calibration (RMSEC) and full cross validation (RMSECV). The results of selected models were 0.8976 (R²p), 6.0207 kgf (RMSEP) with gaussian filter of smoothing, 0.8379 (R²p), 0.2674°Bx (RMSEP) with the mean of normalization, and 0.7779 (R²p), 0.1033% (RMSEP) with median filter of smoothing for firmness, soluble solid content (SSC), and acid content, respectively. Results show that Vis / NIR hyperspectral reflectance imaging technique has good potential for the measurement of internal quality of truss tomato.

백비심에서 자연 발생한 신장의 칸디다증

김대용(Dae Yong Kim),유한상(Han Sang Yoo),배지선(Ji Seon Bae),최재훈(Jae Hoon Choi),박주연(Ju Yeon Park),김영근(Young Kun Kim),정영목(Young Mok Jung) 한국수의병리학회 1999 한국수의병리학회지 Vol.3 No.2

혈관조영상 잠재혈관기형에 대한 선형가속기형 정위방사선수술의 임상경험

김대용(Dae Yong Kim),안용찬(Yong Chan Ahn),이정일(Jung Il Lee),남도현(Do-Hyun Nam),임도훈(Do Hoon Lim),이정은(Jeong Eun Lee),여인환(Inhwan J Yeo),허승재(Seung Jae Huh),노영주(Young Joo Noh),신성수(Seong Soo Shin),홍승철(Seung-Chyul H 대한방사선종양학회 2001 Radiation Oncology Journal Vol.19 No.1

목 적 :혈관조영상 잠재혈관기형(angiographically occult vascular malformation, AOVM)의 치료에 정위방사선수술을 적용하여 병변의 영상학적 반응과 임상 경과, 치료에 대한 부작용을 분석하여 AOVM의 치료 시 정위방사선수술의 역할을 정립하고자 한다. 대상 및 방법 : 1995년 2월부터 1999년 12월까지 AOVM으로 진단 받은 11명(12병변)의 환자에 대하여 선형가속기를 이용한 정위방사선수술을 시행하였다. 모든 병변은 자기공명영상에서 병변의 중심부에는 이질적인 고신호를 보이며, 저신호의 테두리로 둘러 쌓여 경계가 분명한 혈관기형 소견을 보였다. 정위방사선수술 시 처방선량은 회전중심점 선량 기준으로 67∼80% (중앙값 80%) 등선량곡면에 13∼25 Gy (중앙값 16 Gy)이었으며, 모두 단일 회전중심점을 이용하였고, 8∼20 mm (중앙값 14 mm) 크기의 원형 콜리메이터를 사용하였다. 결 과 :추적관찰 기간은 12∼56개월(중앙값 42개월)이었다. 재출혈이 일어난 경우는 3예로 치료 후 5, 6, 12개월 때 각 1차례씩 발생하였고 이후 추가적인 재출혈은 없었다. 정위방사선수술로 인한 조직괴사는 2예에서 발생하였으며, 모두 영구적인 신경학적 후유증을 초래하였다. 임상증세를 동반하지 않은 채 T2 강조영상에서 병변 주위의 부종이 관찰된 경우도 1예 발생하였다. 결 론 :정위방사선수술을 이용한 AOVM의 치료는 재출혈을 효과적으로 방지할 수 있는 치료방법으로 생각된다. 그러나 동정맥기형에 비하여 신경학적 후유증이 발생할 확률이 높기 때문에 치료 환자의 선택과 처방선량의 결정 시에는 보다 신중한 고려가 필요하다 Purpose :To establish the role of stereotactic radiosurgery (SRS) for the treatment of patients with angiographically occult vascular malformation (AOVM). Materials and Methods : Eleven patients (12 lesions) with AOVM were treated with linear acceleratorbased SRS between February 1995 and December 1999. A magnetic resonance imaging of each patients showed well- circumscribed vascula r lesion with reticulated core of heterogeneous signal intensity and peripheral rim of low signal intensity. SRS were performed with the median peripheral dose of 16 Gy (range 13∼25). A single isocenter was used with median collimator size of 14 mm (range 8∼20) diameter. Results :With a median follow- up period of 42 months (range 12∼56), rebleeding occurred in 3 AOVMs at 5, 6 and 12 months after SRS but no further bleeding did. Two patients experienced radiation- induced necrosis associated with permanent neurologic deficit and one patient showed transient edema of increased T2 signal intensity. Conclusion : SRS may be effective for the prevention of rebleeding in AOVM located in surgically inaccessible region of the brain. Careful consideration should be needed in the decision of case selection and dose prescription because the incidence of radiation- induced complications is too high to be accepted.