加味歸脾湯으로 호전된 불면 환자 치험 1례

김근엽,박종일,고흥,김기태,신선미,Kim, Geun-yeob,Park, Jong-il,Ko, Heung,Kim, Ki-tae,Shin, Son-mi 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.5

Objective: To report the effect of Gamiguibi-tang (加味歸脾湯) as a treatment for insomnia. Methods: An insomnia patient who scored 27 points for her insomnia severity index was enrolled in this study. She received oriental treatment with herbal medication (Gamiguibi-tang), acupuncture, and moxibustion for 1 month. Results: After treatment, sleep duration and sleep quality were improved. After the patient had taken Gamiguibi-tang, her score for the Pittsburgh Sleep Quality Index (PSQI) decreased from 21 to 9, and associated symptoms were also improved without taking sleeping pills. Conclusions: Gamiguibi-tang is effective for the treatment of insomnia. More clinical data and studies are required in patients suffering from insomnia.

장기간 한약 복용한 뇌졸중 환자의 간 및 신장 기능 수치 변화에 대한 증례 보고

김근엽,김기태,고호연,고흥,신선미,Kim, Geun-yeob,Kim, Gi-tae,Go, Ho-yeon,Ko, Heung,Shin, Seon-mi 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.5

Objectives: This case report describes a patient who had suffered a stroke and who was treated for a long period with herbal medicine in combination with a Western medicine. Methods: Changes in liver function and renal function laboratory tests were measured while the patient took herbal medicine during the 1190 days of hospitalization. Results: During the hospitalization period, the liver function test (LFT) levels were elevated two fold, but after taking the herbal medicine, the LFT levels were stabilized and have remained stable since. Conclusions: The high risk of prescribing herbal medicine by an unlicensed person and the possibility of long-term herbal medicine usage for stabilizing liver function test were shown.

한방병원 입원 환자에서 약인성 간 손상 발생율과 약인성 간 손상 환자 치험례

김근엽,정누리,최유진,신선미,김기태,고흥 대한한방내과학회 2020 大韓韓方內科學會誌 Vol.41 No.3

From January 2014 to December 2016, 38 out of 153 inpatients admitted to the Korean Medicine Hospital for more than one month underwent follow-up blood tests to evaluate their liver function levels, and one drug-induced liver injury (DILI) patient was observed. 1. At the time of admission, six (15.8%) of the 38 patients had abnormal alanine aminotransferase (ALT) levels and five of them recovered after hospitalization. 2. At follow-up, two (5.3%) patients had a Council for International Organizations of Medical Science (CIOMS)-based liver injury. One was identified as a liver injury accompanied by pneumonia, and one was judged as a liver injury caused by the drug. 3. The patient had a suspected DILI and completely recovered after 13 days while discontinuing the herbal medication and by using Sanggangunbi-tang (生肝健脾湯).

Nitrous Oxide Emissions from Red Pepper, Chinese Cabbage, and Potato Fields in Gangwon-do, Korea

서영호,김근엽,박기진,김경희,정영상 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.6

The level of nitrous oxide (N2O), a long-lived greenhouse gas, in atmosphere has increased mainly due toanthropogenic source, especially application of nitrogen fertilizers. Quantifying N2O emission fromagricultural field is essential to develop national inventories of greenhouse gases (GHGs) emission. Theobjective of the study was to develop emission factor to estimate direct N2O emission from agricultural fieldin Gangwon-do, Korea by measuring N2O emissions from potato (Solanum tuberosum), red pepper (Capsicumannum L.), and Chinese cabbage (Brassica campestris L.) cultivation lands from 2009 to 2012. AccumulatedN2O emission was 1.48±0.25 kg N2O-N ha-1 for red pepper, 1.27±0.27 kg N2O-N ha-1 for potato, 1.49±0.06 kgN2O-N ha-1 for Chinese cabbage cultivated in spring, and 1.14±0.22 kg N2O-N ha-1 for fall Chinese cabbage. Emission factor of N2O calculated from accumulated N2O emission, nitrogen fertilization rate, and backgroundN2O emission was 0.0051±0.0016 kg N2O-N kg-1 N for cropland in Gangwon province. More extensive studyis deserved to be conducted to develop N2O emission factor for upland crops in Korea through examining theemission factors from various regions and crops because N2O emission is influenced by many factorsincluding climate characteristics, soil properties, and agricultural practices.

Assessment of Nitrous Oxide (N2O) Emissions from Farmland in 2011 with IPCC Guideline Methodology

정현철,김근엽,이종식,최은정,고지연,소규호 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.6

This study was conducted to assess N2O emissions in agricultural soils of Korea under the 1996 IPCC(Intergovernmental Panel on Climate Change) methodology. N2O emissions in agricultural soils werecalculated the sum of direct emission and indirect emission by the N sources and emissions by field burning ofcrop residues. N2O emission was highest in animal manure as 1,547 CO2-eq Gg. Indirect emissions byatmospheric deposition and leaching and runoff were 1,463 and 1,753 CO2-eq Gg, respectively. N2O emissionby field burning of crop residues was highest in pepper due to the residue/crop ratio and field burning ratio.

모야모야병으로 인한 출혈성 뇌졸중 환자 1례에 대한 증례보고

박종일,김근엽,고흥,신선미,김기태,Park, Jong-il,Kim, Geun-yeob,Ko, Heung,Shin, Son-mi,Kim, Ki-tae 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.2

Objective: This case report examined a patient to determine if traditional Korean medicine treatment was effective for treating acute intracerebral hemorrhage (ICH) diagnosed with moyamoya disease.Method: The patient was treated with herbal medicine, acupuncture, and Western medicine and was followed up with for symptoms, vital signs, and brain computed tomography (CT) scans.Results: During the treatment, the patient’s mental state was mostly alert. The patient’s headaches were improved after the use of painkillers; the patient’s fever and blood pressure were well controlled. The cerebral hematoma was removed smoothly.Conclusion: Traditional Korean medical therapy (herbal medicine and acupuncture) along with Western methods appeared to be effective in managing the acute phase of ICH diagnosed with moyamoya disease.

청소년궤양성 대장염 환자의 사상체질요법에 대한 증례보고

박세기,김근엽,신선미,고흥,Park, Se-gi,Kim, Geun-yeob,Shin, Seon-mi,Ko, Heung 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.4

Objectives: This study discusses the effects of constitution therapy on adolescent ulcerative colitis. Methods: A 12-year-old male patient was treated with western medication for six months and herbal medicine for one year and six years; however, his abdominal pain, mucousy stool, bloody stool, and diarrhea persisted. He was diagnosed as having Taeumin according to Sasang constitution classification and treated with Sasang constitutional medicine (i.e., Yeuldahanso-tang and food restrictions based on constitutional medicine theory). Before the first treatment, his Pediatric Ulcerative Colitis Activity Index (PUCAI) score was 35, but this score decreased to 15 within six months and was maintained at 10 by 18 months of treatment. He took the herbal medication for 38 months, and his PUCAI score was 0 at the end of treatment. His liver functioned normally despite long-term drug use, and a follow-up colonoscopy showed no ulcerative colitis except melanosis, which was presumed to be caused by the herbal medicine. Ulcerative colitis in pediatric adolescents requires treatment with pharmacotherapy and dietary control based on constitutional medicine to maintain disease remission. Conclusions: Constitutional therapy is effective for treating adolescent ulcerative colitis. More clinical data are needed for patients with ulcerative colitis.

A Case Study to Estimate the Greenhouse-Gas Mitigation Potential on Conventional Rice Production System

유종희,이종식,김계훈,김근엽,최은정 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.6

To estimate greenhouse gas (GHG) emission, we established inventory of conventional rice cultivation fromfarmers in Gunsan and Iksan, Jeonbuk province in 2011∼2012. This study was to calculate carbon footprintand to analyse the major factor of GHGs. We carried out a sensitivity analysis using the analyzed main factorsof GHGs and estimated the mitigation potential of GHGs. Also we tried to suggest agricultural methods toreduce GHGs that farmers of this case study can apply. Carbon footprint of rice production unit of 1 kg was2.21 kg CO2.-eq. kg-1. Although amount of CO2 emissions is largest among GHGs, methane had the highestcontribution of carbon footprint on rice production system after methane was converted to carbon dioxideequivalent (CO2-eq.) multiplied by the global warming potential (GWP). Source of CO2 in the cultivation ofrice farming is incomplete combustion of fossil fuels used by agricultural machinery. Most of the CH4 emittedduring rice cultivation and major factor of CH4 emission is flooded paddy field in anaerobic condition. Mostof the N2O emitted from rice cultivation process and major sources of N2O emission is application of fertilizersuch as compound fertilizer, urea, orgainc fertilizer, etc. As a result of sensitivity analysis due to the variationin energy consumption, diesel had the highest sensitivity among the energies inputs. If diesel consumption isreduced by 10%, it could be estimated that CO2 potential reduction is about 2.5%. When application rate ofcompound fertilizer reduces by 10%, the potential reduction is calculated to be approximately 1% for CO2 andapproximately 1.8% for N2O. When drainage duration is decreased until 10 days, methane emissions isreduced by approximately 4.5%. That is to say drainage days, tillage, and reducing diesel consumption werethe main sources having the largest effect of GHG reduction due to changing amount of inputs. Accordingly,proposed methods to decrease GHG emissions were no-tillage, midsummer drainage, etc.

Investigation on Regional Distribution of Potential Energy Production with Agricultural By-Products in Agricultural Sector

박우균,이선일,신중두,김근엽,김이현,소규호 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.5

The objectives of this study were to estimate the potential biomass yield by using the biomass conversion index and evaluate the potential energy production by using the energy conversion index of biomass. Estimating the total biomass yield in Korea showed 9,646.3 thousand tons produced in 2012. Subsequent evaluation of the potential energy production using the estimated biomass yield in 2012 indicated that the calorific values were varied from 3,800 to 4,500 kcal kg-1 for crop- and from 4,100 to 4,300 kcal kg-1 for woody-based biomass, respectively. Among the examined biomass materials, the pruned branch of a nut tree appeared to be the greatest in bio-energy production showing 6,300 kcal kg-1 in calorific value. Total potential energy production from agricultural by-products was estimated approximately at 3,966,000 TOE. Among the agricultural by-products examined, rice straw showed the greatest energy production potential being at 2,321,000 TOE. Furthermore, it might contribute to establishing the countermeasures of biomass utility in agricultural sector based on regional distribution chart of the potential biomass and energy yields in Korea.

Assessment of Methane (CH4) Emissions from Rice Paddy and Crop Residues Burning in 2011 with the IPCC Guideline Methodology

최은정,이종식,정현철,김근엽,소규호 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.6

Rice cultivation in the paddy field and the burning of crop residues have been identified as the importantsources of methane emission in agricultural sector. This study aimed at assessment of the methane emissionfrom croplands in the year of 2011 with the IPCC guideline methodology. Methane from rice cultivation wasemitted 6,813 CO2-eq Gg in 2011. According to the water management, methane emission amounts bycontinuously flooded and intermittently flooded were 1,499 and 5,314 CO2-eq Gg, respectively. Methaneemission by crop residues burning was highest in red pepper and followed by rice straw, pulses and barely in2011. Methane emission by field burning was very little compared with rice cultivation.