강남콩(phaseolus vulgaris L.)의 지방질 성분

권용주,엄태붕,송근섭,김충기,이태규,양희천,Kwon, Yong-Ju,Uhm, Tai-Boong,Song, Geun-Seoup,Kim, Choong-Ki,Lee, Tae-Kyoo,Yang, Hee-Cheon 한국식품과학회 1987 한국식품과학회지 Vol.19 No.6

강남콩의 지방질을 chloroform-methanol-water (1:2:0.8, v/v)의 용매로 추출하고 이를 silicic acid column chromatography에 의하여 중성지방질, 당지방질 및 인지방질로 분획한 다음 이들의 지방질 조성과 지방산 조성을 TLC, GLC에 의하여 분리 정량하였다. 강남콩의 총지방질 함량은 1.9%이었으며 이중 중성지방질은 48.2%. 당지방질은 7.5%, 인지방질은 44.3%이었다. triglyceride는 중성지방질중 64.6% 함유된 주성분이었으며 가장 함량이 높은 인지방질과 당지방질로서 phosphatidyl choline은 인지방질중 32.9%, esterified steryl glycoside는 당지방질중 38.8% 함유되어 있었다. 강남콩의 주요 지방산은 linolenic, linoleic, oleic, palmitic acid이었으며 특히 linolenic acid는 그 함량이 높아 총지방질의 경우 37.1%, 중성지방질의 경우 50.4% 함유되어 있었다. Lipids of kidney bean were extracted by the mixture of chloroform-methanol-water (1:2:0.8 v/v), fractionated into neutral lipids, glycolipids and phospholipids by silicic acid column chromatography, and the composition of these lipid classes were determined by TLC and GLC. The lipid content of kidney bean was 1.9%, and the lipid was consisted of 48.3% neutral lipids. 7.5% glycolipids and 44.2% phospholipids. Triglyceride was the major component of neutral lipids (64.6%). The major glycolipid and phosphlolipid were esterified steryl glycoside (38.3%) and phosphatidyl choline (32.9%). The major fatty acids of kidney bean lipid were linolenic, linoleic, palmitic and oleic acid. Linolenic acid contents were very high to be 37.1% in total lipid and 50.5% in neutral lipid.

외상 후 스트레스장애에 대한 한방중재 고찰 -재해정신보건 한의학적 치료 모델 연구-

권용주 ( Yong Ju Kwon ),조성훈 ( Seung Hun Cho ) 대한한방신경정신과학회 2011 동의신경정신과학회지 Vol.22 No.4

Objectives: These days assaults and other natural and human disasters are increasing. But oriental medical treatment researches in Korea are limited in car accident PTSD patients only. Our object is to explore an oriental medical intervention model for the evidence-based approach to PTSD after diverse trauma including disasters. Methods: Domestic papers for Korean researches are obtained from oriental medical related journals by internet searching. International materials are obtained from Pub Med searching and a publication from Department of Veterans` Affairs. After assorting searched articles into RCTs and non-RCTs, we analyzed the articles according to the elapsed time from trauma. Results: We confirmed that acupuncture, CBT, and PMR were effective in acute stage after traumatic event. And EMD R, EFT, and relaxation therapy were effective in chronic stage after traumatic event. Building on the findings, we proposed a model of oriental medicine for Disaster Mental Health. Conclusions: Analyzing previous researches about oriental medicine on PTSD, several interventions were confirmed the effectiveness on specific treatment stage. We could find the possibility of Oriental Medicine as a Disaster Mental Heath and proposed a model of Oriental medicine for Disaster Mental Health.

느타리버섯의 脂肪成分에 관한 硏究

권용주(Yong-Ju Kwon),엄태붕(Tai-Boong Uhm) 한국식품영양과학회 1984 한국식품영양과학회지 Vol.13 No.2

느타리버섯의 지방질을 chloroform methanol(2:1, v/v)로 추출한 후 관, TLC, GLC로 分離, 定量하여 다음과 같은 結果를 얻었다.<br/> 1. 느타리버섯은 약 0.51%의 粗脂肪質을 함유하고 있었으며, 그 중 중성지질은 33.8%, 당지질은 19.7%, 인지질은 46.5% 이었다.<br/> 2. 중성지질중에는 triglyceride (38.2%), free fatty acid (20%) free stem1 (10%)가 주성분이었고 그 외 에 diglyceride, monoglycerides, sterol-ester와 3 가지 미확인 성분이 존재하였다.<br/> 3. 당지질 중에는 steryl glycosides (28.9%)와 esterified steryl glycoside (23.7%)가 주성분이었으며 이외에 digalactosyl diglyceride, monogalactosyl diglyceride와 2 가지 미확인 당, 지질성분이 존재하였다.<br/> 4. 인지질중에는 phosphatidyl choline과 serine (48.2%), phosphatidyl ethanol amine (44.4%)이 주성분이었고 phosphatidyl inositol도 소량 존재하였다.<br/> 5. 중성지질의 주요지방산은 linoleic (34.2%), palmitoleic (21.7%), oleic (17.7%) 및 palmitic acid(15.3%)였다. 당지질의 주요지방산은 linoleic (47.4%)과 palmitic acid(15.7%)였으며, 인지질의 주요지방산 역시 linoleic (72.3%)과 palmitic acid (16.5%)였다. Lipids in oyster mushroom (Pleurotus florida) were extracted by the mixture of chloroform-methanol (2:1, v/v) and fractionated into neutral lipids, glycolipids and phospholipids by silicic acid column chromatography. Components and fatty acid composition of each fraction were determined by thin-layer and gas-liquid chromatographies. Fresh oyster mushroom contained 0.5% total lipid in which the contents of neutral lipids, glycolipids and phospholipids were 33.8%, 19.7% and 45.6%, respectivley. Triglycerides(38.2%), free fatty acids (20%) and free sterols (10%) were the major components among the neutral lipids. Diglycerides, monoglycerides, sterol esters and three unidentified neutral lipids were the minor components. Major components of glycolipids were steryl glycosides(28.9%) and esterified steryl glycosides (23.7%). Digalactosyl diglycerides, monogalactosyl diglycerides and two unknown components were also present. Of the phospholipids, phosphatidyl cholines and serines (48.2%), and phosphatidyl ethanolamines(44.4%) were the major components. On the other hand, the major fatty acids of neutral lipids were linoleic, palmitoleic, oleic and palmitic acid. Linoleic and palmitic acid were the predominant fatty acids of both glycolipids and phospholipids.

가설생성 과정에서 나타나는 학습자의 감성 및 생리적 변화와 가설생성능력의 상관관계 분석

권용주 ( Yong Ju Kwon ),이준기 ( Jun Ki Lee ),이정민 ( Jeong Min Lee ) 경북대학교 중등교육연구소 2009 중등교육연구 Vol.57 No.1

이 연구의 목적은 가설생성과정에서 나타나는 학습자의 감성 및 생리적 변화와 가설생성능력의 상관관계를 알아보는 것이다. 이를 위해 이 연구에서는 적절한 과학적 가설생성 과제를 개발하였다. 연구대상은 현직 중등 과학교사 22명으로 하였다. 피험자들은 과제를 수행하면서 자신이 느낌 감성의 강도를 이모티콘 척도 기록지에 나타내었다. 또한 이들은 과제 수행 전과 후에 타액 호르몬 분석을 위한 시료를 채취하였다. 연구결과, 첫째, 가설생성과정에서 나타나는 긍정감성 및 긍정감성 변화량은 가설생성능력과 유의미한 상관관계가 나타나지 않았다. 둘째, 가설생성과정에서 나타나는 부정감성은 사전-사후의 측정치가 아니라 과제 수행에 따른 사후 변화량이 가설생성능력과 유의미한 정적 상관관계를 나타내었다. 셋째, 학습자의 탐구과제 수행에 따른 감성의 변화는 생리적 변화도 동반하였는데, 부정감성의 변화량과 cortisol의 변화량과는 유의미한 정적 상관성을 보이는 것으로 나타났다. 넷째, 학습자의 탐구과제 수행에 따른 cortisol 변화량은 학습자의 가설생성능력과 유의미한 정적 상관관계를 나타낸다. 다섯째, DHEA는 cortisol과 의미 있는 상관관계를 형성하지만 탐구과정에서 나타나는 학습자의 부정감성이나 가설생성능력과는 유의미한 관계를 나타내지 않는다. The purpose of this study was to analyze the correlations among changes in learner`s emotion, physiological state and hypothesis-generating ability during the scientific hypothesis-generating process. For this study, scientific hypothesis-generating task was developed that are suitable for hypothesis-generating. The tasks was administered to 22 in-service secondary science teachers. After the task, the strength of emotion was measured using adjective emoticon check lists. Then, they extracted their saliva sample twice (before and after the task) for salivary hormone analysis. The results of this study, first, there were no significant correlation between learner`s positive emotion and change of the positive emotion during the hypothesis-generating and their hypothesis-generating ability. Second, learner`s change of the negative emotion during the hypothesis-generating was significantly correlated with their hypothesis-generating ability. Third, learner`s emotional changes during the performing inquiry task were accompanied with their physiological state change, also there were significant positive correlation between change of the negative emotion and cortisol concentration. Fourth, there were significant positive correlation between learner`s cortisol concentration change during the performing inquiry task and their hypothesis-generating ability. Fifth, in the case of DHEA, there were no significant correlation between learner`s change of the negative emotion during the performing inquiry task or their hypothesis-generating ability.

강남콩 (Phaseolus vulgaris L.)의 Triglyceride 조성

권용주(Yong-Ju Kwon),엄태붕(Tai-Boong Uhm),김충기(Choong-Ki Kim),김상필(Sang-Phil Kim),고석범(Seuk-Beum Ko),이태규(Tae-Kyoo Lee),양희천(Hee-Cheon Yang) 한국식품과학회 1987 한국식품과학회지 Vol.19 No.6

X-선(線) 전신조사(全身照射)가 적출(摘出)마우스 십이지장(十二指腸)의 자동성운동(自動性運動) 및 산소(酸素) 소비량(消費量)에 미치는 영향(影響)과 Glucose 및 5-hydroxytryptamine 이 이들에 미치는 효과(效果)

권용주(Kwon, Yong-Ju),주영은(Choo, Young-Eun) 대한생리학회 1970 대한생리학회지 Vol.4 No.2

In an attempt to better understand the effect of whole body irradiation on the spontaneous motility and oxygen consumption rate of the isolated mouse duodenum, a whole body X-irradiation of 1,000r. was given to albino mouse, and 1) the total length of contraction of isolated duodenum was recorded on kymograph every five minutes for 60 minutes, 2) glucose and 5-hydroxytryptamine(5-HT) were added to the reaction medium of Kreb s-Ringer-bicarbonate buffer(KRB) and response of the isolated duodenum to the drugs was observed, and 3) the oxygen consumption rate (QO₂) of the isolated duodenum as well as the effect of glucose and 5-HT on QO₂ were measured by Warburg s standard manometric method and the comparison was made with the control(i.e. normal) group. The results thus obtained are summarized as follows. 1. The spontaneous motility of the isolated duodenum in the irradiated groups showed a significantly elevated pattern for the first 15 minutes comparing with the control. The motility, however, decreased after 15 minutes and remained so in the irradiated groups to the level of the nonirradiated control, but 24 hours post-irradiation group showed a tendency of an increased motility while one hour post-irradiation group showed no difference comparing with the control. 2. Addition of glucose produced generally elevated motility of the isolated duodenum in both irradiated and non-irradiated groups comparing with the control throughout the experiment, but no difference was observed in contractile amplitude between the irradiated and non¡¤irradiated groups. 3. When 5-HT was added to the irradiated group, the contractile amplitude of isolated duodenum was similar to that of the control, and 5-HT alone caused a slight increase of the motility comparing with the control. 4. The oxygen consumption rate (QO₂) of the isolated duodenum was found to be ,slightly increased in one hour post¡¤irradiated group, but similar in 24 hour post¡¤irradiated group comparing with the control. Glucose produced a significant increase of QO₂ in all the groups, but 5-HT produced a tendency of decrease of QO₂ in all the groups.

치매의 한약물 치료에 대한 체계적 임상논문 고찰 -국내문헌을 중심으로-

권용주 ( Yong Ju Kwon ),조혜영 ( Hye Young Cho ),황의완 ( Wei Wan Whang ),조성훈 ( Seung Hun Cho ) 대한한방신경정신과학회 2010 동의신경정신과학회지 Vol.21 No.4

Objectives: This study aimed to evaluate any clinical studies regarding the herbal medicine for dementia focusing on Korean literature for future rigorous clinical research. Methods: Every article relevant to dementia was initially obtained from oriental medical related journals by electronic search at journal web sites or manual searches. Journals were limited to those registered with the Korea Research Foundation. From initial findings, two independent reviewers selected clinical articles and these articles were further analyzed separately by predefined criteria according to prospective and retrospective studies. For randomized controlled trial and non randomized controlled trial, quality assessment was also conducted. Results: From ninety seven patients initially obtained articles, twenty three patients were finally analyzed. One article was randomized controlled study, Four articles were prospective whereas eighteen patients were retrospective. In the qualitative evaluation of prospective articles, there was deduction regarding pre-calculated study size and prospective data collecting. Assessment measurement most frequently used was Mini Mental State Examination. The order of frequency of use herbs were identified. Conclusions: According to our study, the herbal medicine for dementia in general showed a positive effect in the cognitive aspects of dementia patients. Further well-designed randomized controlled studies should be conducted.

나트륨 실측치와 식품교환표 및 식품성분표를 이용한 추정치의 비교

권용주(Yongju Kwon),이무용(Mooyong Rhee),김지영(Jeeyoung Kim),권광일(Kwangil Kwon),김소진(Sojin Kim),신희준(Heejun Shin),박성수(Seongsoo Park),이은주(Eunju Lee),박혜경(Hyekyung Park),박용순(Yongsoon Park) 한국식품영양과학회 2010 한국식품영양과학회지 Vol.39 No.4

나트륨의 과잉섭취가 고혈압의 주요한 위험요인으로 알려져 있는데, 한국인의 성인 하루 평균 소금 섭취량은 영양섭취기준보다 3배 이상 높다. 본 연구에서는 식품교환표를 이용하여 14일간의 식단을 작성하고 조리된 음식의 나트륨 함량을 실제로 측정한 후 식품교환표와 식품성분표에서 계산된 나트륨 추정치와 비교하여, 각각 방법의 정확성 및 문제점을 파악하고자 하였다. 그 결과를 요약하면 아래와 같다. 하루 식단의 나트륨 함량에서 식품교환표로 계산한 추정치는 실측치와 유의한 차이가 났으나, 식품성분표는 실측치와 유사하였다. 음식별 절대값의 비교에서는 식품교환표로 계산한 나트륨 추정치와 식품성분표로 계산한 나트륨 추정치가 모두 실측치와 유의한 차이가 났다. 음식군별 절대값 비교에서는 양념류의 나트륨 함량이 많은 주요리, 부식, 국물요리에서 상당히 유의한 차이가 났으며, 식품교환표로 계산한 추정치, 식품성분표로 계산한 추정치, 실측치간의 차이가 큰 음식들이 모두 주요리, 부식, 국물요리였다. 이상의 결과에 따르면, 단순히 하루 식단의 나트륨 함량 비교에서 식품교환표에 비해 식품성분표의 나트륨 함량이 더 정확하다고 생각할 수 있지만, 음식별 또는 음식군별로 추정치와 실측치간의 차이를 절대값으로 비교한 결과, 식품교환표와 식품성분표의 나트륨 함량 모두 실측치와 차이가 컸다. 특히 나트륨 과잉 섭취의 주요 원인으로 보고되는 양념류의 차이로 장류, 김치 등의 사용이 많은 한국음식에서 식품교환표와 식품성분표를 이용한 추정치와 실측치의 차이가 컸다. 따라서 고혈압 및 신장질환 환자를 위한 저염식단작성시 식품교환표나 식품성분표를 사용할 때 실제 소금량과의 차이를 고려해야한다. Excessive intake of sodium is known as a risk factor for hypertension, and Korean adults consume sodium 3 times higher than Dietary Reference Intakes (DRIs). The purpose of this study was to evaluate the difference on sodium content between analyzed and estimated by food composition table and food exchange list. Seven days of low salt diet and seven days of high salt diet were prepared, and sodium contents were estimated by food composition table and food exchange list and measured by atomic absorption spectrophotometer. Sodium contents of diet per day estimated by food exchange list significantly differed from analyzed content, but those estimated by food composition table were not. However, when absolute differences from analyzed content were compared by dishes in the low and high salt diet periods, there were significant differences among estimated sodium content by food composition table and food exchange list and analyzed sodium content. The discrepancy between those results was due to that absolute value was used to compare sodium contents of dishes but not to compare sodium contents of days. In addition, main dish, side dish, and soup were significantly different among estimated sodium content by food composition table and food exchange list and analyzed sodium content. Actual sodium contents of Jap-Chae Deop-Bap and Roasted chicken with oyster sauce differed to a great extent from estimated contents by food exchange list and food composition table. In conclusion, actual sodium contents of Korean dishes were significantly different from those estimated by food composition table and food exchange list, and thus these differences in salt content should be considered on planning of low-salt menu for hypertensive patients.

모유수유 상담에서 일반적인 질문들과 근거중심 답변

권용주(Yong-Ju Kwon),조선영(Sun-Young Cho) 대한모유수유한의학회 2021 nipple confusion,breastfeeding consultation,IBCLC, Vol.2 No.1

As the world experiences extreme upheaval due to COVID-19, there are much more considerations and decisions for breastfeeding mothers to consider when breastfeeding after childbirth. As a result, there is concern about a decrease in the rate of breastfeeding. Since December 2013, the Korean Academy of Breastfeeding Medicine has been continuously conducting breastfeeding-related consultations through the online consultation bulletin board. From timely questions such as whether it is possible, whether or not herbal treatment is safe during breastfeeding, the truth about food myths to avoid, life-wide problems such as hair perm or cosmetic botox treatment, vague concerns about insufficient milk supply, and ways to increase the actual amount of milk. Answers are all evidence-based and prepared by international breastfeeding consultants made up of IBCLCs and Korean Medical doctors.

과학적 설명 지식의 창의적 생성 과정

권용주(Kwon, Yong-Ju),정진수(Jeong, Jin-Su),강민정(Kang, Min-Jeong),양일호(Yang, Il-Ho) 한국창의력교육학회 2002 창의력교육연구 Vol.5 No.1

이 연구는 과학적 창의력의 의미와 본질, 그리고 과학에서 설명적 지식의 창안 과정에 관한 과학 철학적 논의들을 분석하였다. 이를 통해 다음과 같은 결론을 얻을 수 있었다. 첫째, 과학적 창의력은 자연 현상에서 새롭고 가치 있는 과학적 지식을 창안해 내는 능력이라고 할 수 있다. 그리고 과학적 창의력을 본질적으로 이해하기 위해서는 과학의 기술적 지식, 설명적 지식, 예측적지식의 창안 과정을 밝혀야 한다. 둘째, 과학에서 설명적 지식은 귀추적 사고에 의해서 창안된다. 귀추란 미지의 현 상황을 이미 알고 있는 다른 상황과의 유사성에 바탕을 두고, 이를 차용하여 현 상황을 설명하는 추론의 한 유형이다. The present study is to analyze the arguments about the meaning and essence of scientific creativity and the process of creating scientific explanatory knowledge in the philosophy of science. The results showed that the meaning of scientific creativity is the ability to create new and valuable scientific-knowledge. Also, this study showed that the understanding of the essence of scientific creativity is required to ascertain the process of creating of descriptive knowledge, explanatory knowledge, and predictive knowledge in science. Furthermore, scientifically explanatory knowledge is created by abductive reasoning. Abductive reasoning is the mental process of creating hypotheses in which an explanation is to borrow a tentative explanation from the previously experienced context and apply it to the new context. In addition, the process of creating scientific knowledge for explaining causal question is as follows: (1) analyzing questioning situation, (2) identifying experienced situation (3) identifying causal explicans (4) generating hypothetical explicans. This study also discusses the implications of these findings for teaching and evaluating in science education.