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위점막에서 조직화학적 및 면역조직화학적 염색을 이용한 Helocibaxter pylori 의 검출
백종철(Jong Cheul Baek),강헌석(Heon Seok Kang),이숭(Soong Lee),명재일(Jae Il Myung),김완(Wan Kim),박창수(Chang Soo Park) 대한내과학회 1997 대한내과학회지 Vol.53 No.5
N/A logic test (ELISA, BIO-RAD GAP method), histochemical stain (Warthin-Starry silver stain), immunohistochemical stain (Avidin biotin conjugate method, ABC method) were performed to identify the presence of H. pylori infection. H. pylori infection was defined that 2 of 3 studies were positive. Results: Positive result to H. pylori infection by serologic test, Warthin-Starry silver stain and immunohistochemical stain were 82% (28/34 cases), 65% (22/34 cases), 68% (23/34 cases). Sensitivity and specificity were 68%, 20% in serologic test, 95%, 83% in Warthin-Starry silver stain, 100%, 100% in immunohistochemical stain. Correlation among these tests was best between Warthin-Starry silver stain and immunohistochemical stain. Conclusion: By the above results, we can conclude that histochemical stain and immunohistochemical stain are the most accurate diagnostic method to identify the infectivity of R. pylori.
이숭(Soong Lee),강헌석(Heon Seok Kang),백종철(Jong Cheir Back),김윤미(Yun Mee Kim) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.5
Gastric multiple carcinoids with bleeding is very rare disease. A 62-year-old male patient was admitted to the hospital because of hematemesis and melena. On the gastrofiberoptic examination, blood clots, multiple small round polypoid masses in fundus and large round submucosal tumor-like polypoid mass in lesser curvature side of body were noticed. The biopsy specimen of small polypoid mass in gastric fundus by polypectomy snare showed carcinoid tumor in submucosa covered by atrophic mucosa with intestinal metaplasia and positive immunohistochemical stain for chromogranin A, neuron-specific enolase, cytokeratin. So we report a case of gastric multiple carcinoids with a review of relevant literature. (Korean J GastroenteroJ 1996;2S:721 - 726)
김영진,김완,이숭,김윤미,명재일,강헌석,백종철,김용록 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.4
Primary adenocarcinoma of the duodenum is a rare disease, representing 0.35% of all gastrointestinal neoplasm and 0.042% of all malignant neoplasm. Since Ham-burger described the first duodenal caricinoma in 1746, the incidence has shown an increasing tendency. Compared with upper gastrointestinal contrast studies, the gastroduodenoscopy has gained an increasing popularity as an invesitigative tool in recent years. But the diagnosis is usually made at a very late stage because the symptoms are often non-specific, which contributes to delayed diagonsiss and poorer prognosis. We have experienced two cases of the primary carcinoma of the duodenal bulb and one case of carcinoma of the second portion, which were diagnosed by biopsy with gastrofiberoscopic endoscopy and operative finding. So we report three csses with a brief review of literature.
이형우,임종철,김용록,김완,명재일,강헌석,염형렬,류형선,고향미,백종철 대한내과학회 1999 대한내과학회지 Vol.56 No.6
Cutaneous metastases from gastric carcinoma are uncommon. The frequency of metastses to the skin from gastric carcinoma have ranged from 0.3% to 0.4%. Carcinoma en cuirasse, first described by Velpeau in 1838, is marked sclerodermatous change and characterized by a difffuse morphea-like induration of the skin and represents a rare manifestations of breast carcinoma metastatic to the chest wall. It is vary rarely seen in lung, stomach, kidney and other metastasizing malignancies. We report a case of carcinoma en cuirase and nodular carcinoma from gastric carcinoma in a 36-year-old male who complained chiefly of multiple cutaneous nodules. He had mixed lesions of an erythematous morphea-like induration on the neck and multiple erythematous nodules on the chest and abdomen. Gastroscopy finding showed a Borrmann type Ⅳ advanced gastric carcinoma. Histopathologic examination of skin and stomach showed atypical cells with pleomorpic, hyperchromatic nuclei and scanty, eosinophilic cytoplasm, which are consistent with poorly differentiated adenocarcinoma. Immunohistochemical stainings showed positive reaction for cytokeratin. He died three months after the appearance of cutaneous lesions.
임종철,김명성,이남훈,이대호,명재일,강헌석,김한균,염형렬,류형선,김완,고향미 대한소화기내시경학회 2001 Clinical Endoscopy Vol.22 No.1
Gastric lipoma is rare submucosal tumor, accounting for less than 3% of all be- nign gastric tumor. Most are usually asymptomatic, but on occasion, they may present with abdominal pain, obstruction, dyspepsia, intussuception and gastrointestinal bleeding. Surgical resection is definitive diagnostic and therapeutic procedure. Surgical removal of gastric lipoma should be considered in the following situations: 1) the lesion is large, 2) the lesion is difficult to differentiate from malignant tumor, 3) the patient is symptomatic or has recurrent bleeding or obstruction. We report a case of gastric lipoma with bleeding in a 67-year-old male. Gastroscopy showed active gastric ulcer with fresh blood clot. Although medical conservative treatment was done, bleeding was continued. We referred patient to general surgical department for open surgical procedure and subtotal gastrectomy was performed. Histopathological examination of surgical gastric segment showed 5 x 5.5 cm sized ulcerated mass. Microscopic finding of cross section showed uniform and mature adipose cell, finding consistent with lipoma. We confirmed it submucosal gastric lipoma with ulcer bleeding.