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Cathepsin D의 발현이 비소세포 폐암의 예후에 미치는 영향
염형렬 ( Yeom Hyeong Lyeol ),명재일 ( Myeong Jae Il ),임종철 ( Im Jong Cheol ),김한균 ( Kim Han Gyun ),이남훈 ( Lee Nam Hun ),이대호 ( Lee Dae Ho ),고향미 ( Go Hyang Mi ),문종영 ( Mun Jong Yeong ),강헌석 ( Kang Heon Seog ),류형선 대한결핵 및 호흡기학회 2000 Tuberculosis and Respiratory Diseases Vol.49 No.1
이형우,임종철,김용록,김완,명재일,강헌석,염형렬,류형선,고향미,백종철 대한내과학회 1999 대한내과학회지 Vol.56 No.6
Cutaneous metastases from gastric carcinoma are uncommon. The frequency of metastses to the skin from gastric carcinoma have ranged from 0.3% to 0.4%. Carcinoma en cuirasse, first described by Velpeau in 1838, is marked sclerodermatous change and characterized by a difffuse morphea-like induration of the skin and represents a rare manifestations of breast carcinoma metastatic to the chest wall. It is vary rarely seen in lung, stomach, kidney and other metastasizing malignancies. We report a case of carcinoma en cuirase and nodular carcinoma from gastric carcinoma in a 36-year-old male who complained chiefly of multiple cutaneous nodules. He had mixed lesions of an erythematous morphea-like induration on the neck and multiple erythematous nodules on the chest and abdomen. Gastroscopy finding showed a Borrmann type Ⅳ advanced gastric carcinoma. Histopathologic examination of skin and stomach showed atypical cells with pleomorpic, hyperchromatic nuclei and scanty, eosinophilic cytoplasm, which are consistent with poorly differentiated adenocarcinoma. Immunohistochemical stainings showed positive reaction for cytokeratin. He died three months after the appearance of cutaneous lesions.
임종철,김명성,이남훈,이대호,명재일,강헌석,김한균,염형렬,류형선,김완,고향미 대한소화기내시경학회 2001 Clinical Endoscopy Vol.22 No.1
Gastric lipoma is rare submucosal tumor, accounting for less than 3% of all be- nign gastric tumor. Most are usually asymptomatic, but on occasion, they may present with abdominal pain, obstruction, dyspepsia, intussuception and gastrointestinal bleeding. Surgical resection is definitive diagnostic and therapeutic procedure. Surgical removal of gastric lipoma should be considered in the following situations: 1) the lesion is large, 2) the lesion is difficult to differentiate from malignant tumor, 3) the patient is symptomatic or has recurrent bleeding or obstruction. We report a case of gastric lipoma with bleeding in a 67-year-old male. Gastroscopy showed active gastric ulcer with fresh blood clot. Although medical conservative treatment was done, bleeding was continued. We referred patient to general surgical department for open surgical procedure and subtotal gastrectomy was performed. Histopathological examination of surgical gastric segment showed 5 x 5.5 cm sized ulcerated mass. Microscopic finding of cross section showed uniform and mature adipose cell, finding consistent with lipoma. We confirmed it submucosal gastric lipoma with ulcer bleeding.