Increased Serum Level of CCL5 in Children with Attention‑Deficit/Hyperactivity Disorder: First Results about Serum Chemokines

Ahmet Ö,zaslan,Esra Gü,ney,Ö,zlem Gü,lbahar,Dicle Bü,yü,ktaskin,Burak Arslan 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.1

Objective: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder and its aetiology is not fully understood. This study aimed to determine whether the CCL5 and CCL11 influence the ADHD aetiology by comparing serum CCL5 and CCL11 levels of children with ADHD and typical development. Methods: This study included 45 (27 males, mean age = 8.9 ± 1.7 years) treatment-naive patients diagnosed with ADHD and 35 (20 males, mean age = 8.8 ± 1.6 years) healthy controls. Participants ranged in age between 6−12 years and completed the Conners Teacher Rating Scale that assesses ADHD presentation and severity. CCL5 and CCL11 serum levels were also measured using enzyme-linked immunosorbent assay kits. Results: Significantly higher serum CCL5 levels were found in children with ADHD compared to healthy controls (p < 0.001). No significant difference was found between the mean serum CC11 level of the patients and controls (p = 0.93). In addition, there was no significant correlation between the serum CCL5 and CCL11 levels and predominant presentations of ADHD and disease severity. Conclusion: This study suggests that there are higher levels of serum CCL5 in drug naive children with ADHD, this findings suggest that CCL5 might play a role in the pathophysiology of ADHD. Moreover, these changes in peripheral blood may have therapeutic value. In addition, these results help to understand the role of chemokines in elucidating the etiopathogenesis of ADHD. Our results can be considered as the first step in investigating the role of CCL5 in ADHD, and further research is needed to support these initial findings.

Current–voltage characteristics of Al/Rhodamine-101/n-GaAs structures in the wide temperature range

Ö. Vural,Y. S afak,S . Altındal,A. Türüt 한국물리학회 2010 Current Applied Physics Vol.10 No.3

The forward bias current–voltage (I–V) characteristics of Al/Rhodamine-101/n-GaAs structure have been investigated in the temperature range of 80–350 K. It has been seen a decrease in ideality factor (n) and an increase in the zero-bias barrier height (BH) with an increase in temperature. It has been seen that such a behavior of the BH and n obey Gaussian distribution of the BHs due to the BH inhomogeneities at the metal/semiconductor (MS) interface. The very strong temperature dependence of ideality factor of the structure has shown that the current processes occurring in the organic layer at the MS interface would be a possible candidate such as trap-charge limited conduction in determining the current at the intermediate and high bias regimes. Furthermore, it has been show that the Rh101 can be used to vary effective BHs for the metal/GaAs Schottky diodes. As a result, it has been determined that the BH value for conventional Al/n-GaAs SBD is remarkably higher than our own values of 0.68 eV obtained for the Al/Rh101/n-GaAs at 290 K.

Seismic vulnerability assessment criteria for RC ordinary highway bridges in Turkey

Ö. Avsar,A. Yakut 국제구조공학회 2012 Structural Engineering and Mechanics, An Int'l Jou Vol.43 No.1

One of the most important and challenging steps in seismic vulnerability and performance assessment of highway bridges is the determination of the bridge component damage parameters and their corresponding limit states. These parameters are very essential for defining bridge damage state as well as determining the performance of highway bridges under a seismic event. Therefore, realistic damage limit states are required in the development of reliable fragility curves, which are employed in the seismic risk assessment packages for mitigation purposes. In this article, qualitative damage assessment criteria for ordinary highway bridges are taken into account considering the critical bridge components in terms of proper engineering demand parameters (EDPs). Seismic damage of bridges is strongly related to the deformation of bridge components as well as member internal forces imposed due to seismic actions. A simple approach is proposed for determining the acceptance criteria and damage limit states for use in seismic performance and vulnerability assessment of ordinary highway bridges in Turkey constructed after the 1990s. Physical damage of bridge components is represented by three damage limit states: serviceability,damage control, and collapse prevention. Inelastic deformation and shear force demand of the bent components (column and cap beam), and superstructure displacement are the most common causes for the seismic damage of the highway bridges. Each damage limit state is quantified with respect to the EDPs: i.e. curvature and shear force demand of RC bent components and superstructure relative displacement.

Formulating Reduced-fat Sausages with Quinoa or Teff Flours: Effects on Emulsion Characteristics and Product Quality

Burcu Ö,ztü,rk-Kerimoğ,lu,Hü,lya Serpil Kavuş,an,Damla Tabak,Meltem Serdaroğ,lu 한국축산식품학회 2020 한국축산식품학회지 Vol.40 No.5

This study dealt with the use of quinoa flour (QF) or teff flour (TF) as partial beef fat replacers in the formulation of emulsion-type sausages. A control (C) group was manufactured with 20% beef fat, while the other three groups were formulated with 10% beef fat plus 5% QF (Q), 5% TF (T), and 2.5% QF+2.5% TF (QT). Water-holding capacity of the emulsions was higher in Q (81.81%), T (82.20%), and QT (84.10%) samples than in C (64.83%) samples. Total expressible fluid and expressible fat were the lowest in Q and T samples, indicating the highest emulsion stability of those groups. Incorporation of QF and TF into formulations increased moisture and carbohydrate contents while decreased fat and energy values. Besides, the use of QF was effective to increase protein and dietary fiber contents. T sausages had lower luminosity (L*) and higher yellowness (b*) than C sausages, whilst Q sausages did not result in significant color changes. Higher cook yield values were recorded in Q (97.96%), T (98.21%), and QT (98.15%) samples compared with C (96.44%) samples. Inclusion of QF and TF to formulation led to lower hardness and gumminess, while utilization of TF was also effective to decrease chewiness. Consequently, healthier emulsified sausages were obtained by the inclusion of QF or TF that could decrease the fat content more than 50% without sacrificing overall quality, bringing advantages by quinoa over teff for increasing nutritional value and leading minimal modifications on color and texture.

The Relationship of Male Infertility with Somatosensory Amplification, Health Anxiety and Depression Levels

Ü,nal Ö,ztekin,Yunus Hacimusalar,Abdullah Gü,rel,Ozgul Karaaslan 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.4

Objective The purpose of this study was to investigate the relationship between infertility and factors such as anxiety, health anxiety, depression, and somatosensory amplification in male patients presenting with infertility. Methods In this study, we evaluated 198 patients (infertile group: 130, control group: 68). Patients that fit the inclusion criteria were informed about the aim and method of the study and filled out sociodemographic data collection form, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), The Somatosensory Amplification Scale (SSAS), and Health Anxiety Inventory (HAI) questionnaires. Results The mean scores for SSAS, HAI, BAI, and BDI were significantly higher in the infertility group compared to the control group (p<0.001 for all comparisons). Moreover, the mean scores of the patients in the primary infertile group (n=107) were significantly higher than in the secondary infertile group (n=23) (p<0.05 for all comparisons). Logistic regression analysis revealed that infertility had a significant effect on age, HAI and BDI. Conclusion Psychiatric evaluation of infertile patients may contribute to more efficient use of health services, may reduce the negative effects of anxiety and depression on fertility, and in turn, increase the success of infertility treatment. Therefore, we recommend that each patient presenting with infertility undergoes psychiatric evaluation as part of their treatment.

Refugees and the Informal Labour Market: Evidence from Syrian Inflows to Turkey

Abdullah Selim Ö,ZTEK 한국계량경제학회 2021 JOURNAL OF ECONOMIC THEORY AND ECONOMETRICS Vol.32 No.2

The paper analyses the labour market effects of the Syrian refugees on Turkish natives. Results suggest that there are no negative effects on native employment, but there is a compositional change in the labour market. On the contrary, there is evidence for positive effects on formal employment which is confirmed by the administrative data. By gender, results are differentiated in a systematic way. For men, while there is an increase in formal employment, informal employment decreases. Results are the opposite for women. There is a reduction in formal employment but no significant change in informal female employment. These results suggest that while refugees are substitutes for women in the formal market and men in the informal market, they are complements to formal male workers.

The Effects of Smartphone and Internet Gaming Addiction on Eating Attitudes Among University Students

Bahar Yeş,il Ö,rnek,İ,brahim Gü,ndoğ,muş 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.1

Objective Smartphone addiction is a public health problem increasing with the technologic developments. It particularly affects the university students negatively in terms of psychological, physical, academic achievement and social relations. This study aims to investigate the relation of eating attitudes between smartphone addiction and internet gaming disorder, also the relation of smartphone addiction with obesity.Methods This cross-sectional and prospective study is consisted of 358 volunteer university students. Socio-demographic data form, Short Form of Smartphone Addiction Scale (SF-SAS), Eating Attitude Test (EAT), and internet gaming disorder scale were administered to the participants.Results Mean age of the participants was 22.27±3.10 years and 59.8% (n=214) were female. In terms of the variables “body mass index, body weight, faculty of the student, economic status of the family, and the people they live with together” were significantly different from controls. Also “monthly mobile phone invoice, EAT score, SF-SAS scores” were statistically different. A significant difference was found among “body weight groups” in terms of both EAT score and SF-SAS. According to the linear regression model variables of “gender, smartphone addiction, and school year” were determined as the predictors for EAT.Conclusion Our current study has revealed the relation between smartphone addiction and eating attitudes, and obesity. Smartphone addiction may lead to an increase in body weight, by affecting eating attitudes. Therefore, the effect of eating behavior disorders in the emergence of the smartphone addiction should be considered. Multi-disciplinary solutions are required to prevent this addiction that may increase over time.

An Investgation About the Relationship Between Vasopressin and Oxytocin in Persistent Type Functional Neurological Symptom Disorder

Bahar Yeş,il Ö,rnek,Birgü,l Elbozan Cumurcu,Esra Porgali Zayman 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.10

Objective Functional neurogical symptom disorder (FNSD) is a somatic symptom disorder with loss of voluntary motor or sensory functions, which cannot be explained by another medical condition. The study aimed to examine the relationship of vasopressin and oxytocin in persistent type FNSD. Methods This study included 27 female patients between the ages of 20-57 who were diagnosed with FNSD according to DSM-5 and 27 healthy controls matched in terms of age and gender. Serum vasopressin and oxytocin levels were measured twice on the same day in fasting blood samples and the results were compared statistically. Results Vasopressin were lower in patients compared to controls while there was no difference between oxytocin levels. Childhood traumas were more common in patient group, and mean oxytocin level was lower in patients who exposed to childhood trauma, compared to controls. No significant difference was found between the groups in terms of vasopressin. Conclusion Changes in vasopressin and oxytocin balance in the pathogenesis of persistant FNSD, may likely to lead to physiological and behavioral consequences. Lower oxytocin levels may also be a marker of exposure to childhood trauma in FNSD. These neuropeptides plays important role in neuroendocrine balance of emotional behavior.

One relator quotients of the extended modular group

S. Ikikardes,Ö. Koruoglu,R. Sahin,I. N. Cangül 장전수학회 2008 Advanced Studies in Contemporary Mathematics Vol.17 No.2

In this paper, we obtain one relator quotients of the extended modular group by adding an extra relation to the existing two relations. Then, we show that some of one-relator quotients of ┍ are M-groups.

Oxytocin and Vasopressin Levels and Related Factors in Adolescents with Social Phobia and Other Anxiety Disorders

Necati Uzun,Ö,mer Faruk Akç,a,İ,brahim Kılınç,Tevfik Balcı 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.2

Objective: This study aimed to determine whether a difference exists in plasma oxytocin and vasopressin levels among social anxiety disorder, other anxiety disorders, and healthy control groups in adolescents. The relationship between several psychiatric variables (i.e., state and trait anxiety, social anxiety, childhood trauma, and behavioral inhibition) and oxytocin or vasopressin levels were also investigated in adolescents with anxiety disorders. Methods: The study included three groups of adolescents: social anxiety disorder (n = 29), those with other anxiety disorders (n = 27), and the control group (n = 28). The participants filled out self-report scales to determine various psychological variables. Oxytocin and vasopressin levels were determined from the blood samples of the participants. Results: The oxytocin levels did not show a significant difference between the social anxiety disorder group and the other anxiety disorders group. However, the oxytocin levels were significantly higher in the social anxiety disorder and other anxiety disorders groups than in the control group. The vasopressin levels did not show a significant difference among the groups. According to the hierarchical regression analysis, the state and trait anxiety levels predicted oxytocin in opposite directions. Oxytocin showed positive and negative relationship with trait and state anxiety respectively. No predictive factors were found for the vasopressin levels. Conclusion: We found that the oxytocin levels of adolescents with social anxiety disorder were not different from those of adolescents with other anxiety disorders. Further studies can improve our knowledge of the relationship among anxiety disorders and oxytocin or vasopressin.