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Fuat Gu¨ zel,Hasan Sayg˘ılı,Gu¨ lbahar Akkaya Sayg˘ılı,Filiz Koyuncu 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.5
A new nanoporous carbon from tomato paste waste (TWNC) was prepared. The surface area, total pore volume, average pore diameter of TWNC was found as 722.17 m2 g-1, 0.476 cm3 g-1 and 2.644 nm, respectively. The effects of solution pH, adsorbent dose, initial concentration, ionic strength, contact time, and temperature were studied. Adsorption kinetics was found to be best represented by the pseudo second order model. Isotherm data were fitted well to the both Langmuir and Freundlich models. Maximum adsorption capacity was found as 68.97 mg g-1 at 50 ℃. Thermodynamic parameters showed that the process was spontaneous and endothermic.
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Ahmet Ö,zaslan,Esra Gü,ney,Ö,zlem Gü,lbahar,Dicle Bü,yü,ktaskin,Burak Arslan 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.1
Objective: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder and its aetiology is not fully understood. This study aimed to determine whether the CCL5 and CCL11 influence the ADHD aetiology by comparing serum CCL5 and CCL11 levels of children with ADHD and typical development. Methods: This study included 45 (27 males, mean age = 8.9 ± 1.7 years) treatment-naive patients diagnosed with ADHD and 35 (20 males, mean age = 8.8 ± 1.6 years) healthy controls. Participants ranged in age between 6−12 years and completed the Conners Teacher Rating Scale that assesses ADHD presentation and severity. CCL5 and CCL11 serum levels were also measured using enzyme-linked immunosorbent assay kits. Results: Significantly higher serum CCL5 levels were found in children with ADHD compared to healthy controls (p < 0.001). No significant difference was found between the mean serum CC11 level of the patients and controls (p = 0.93). In addition, there was no significant correlation between the serum CCL5 and CCL11 levels and predominant presentations of ADHD and disease severity. Conclusion: This study suggests that there are higher levels of serum CCL5 in drug naive children with ADHD, this findings suggest that CCL5 might play a role in the pathophysiology of ADHD. Moreover, these changes in peripheral blood may have therapeutic value. In addition, these results help to understand the role of chemokines in elucidating the etiopathogenesis of ADHD. Our results can be considered as the first step in investigating the role of CCL5 in ADHD, and further research is needed to support these initial findings.
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Applying nano-HA in addition to scaling and root planing increases clinical attachment gain
Özge Uysal,Gülbahar Ustaoğlu,Mustafa Behçet,Önder Albayrak,Mustafa Tunalı 대한치주과학회 2022 Journal of Periodontal & Implant Science Vol.52 No.2
Purpose: This study evaluated the efficacy of treating periodontitis using subgingival nanohydroxyapatite powder with an air abrasion device (NHAPA) combined with scaling and root planing (SRP). Methods: A total of 28 patients with stage III periodontitis (grade B) were included in this study, although 1 was lost during follow-up and 3 used antibiotics. The patients were divided into a test group and a control group. All patients first received whole-mouth SRP using hand instruments, and a split-mouth approach was used for the second treatment. In the test group, the teeth were treated with NHAPA for 15 seconds at 70% power per pocket. Subgingival plaque samples were obtained from the 2 deepest pockets at the test and control sites before treatment (baseline) and 3 months after treatment. The full-mouth plaque index (PI), gingival index (GI), papillary bleeding index (PBI), bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were recorded at baseline and at 1- and 3-month post-treatment. Real-time polymerase chain reaction was used to determine the colonisation of Treponema denticola (Td), Porphyromonas gingivalis (Pg), and Aggregatibacter actinomycetemcomitans in the subgingival plaque. Results: From baseline to the first month, the test group showed significantly larger changes in BOP and CAL (43.705%±27.495% and 1.160±0.747 mm, respectively) than the control group (36.311%±27.599% and 0.947±0.635 mm, respectively). Periodontal parameters had improved in both groups at 3 months. The reductions of PI, GI, BOP, PD, and CAL in the test group at 3 months were greater and statistically significant. The total bacterial count and Td and Pg species had decreased significantly by the third month in both groups (P<0.05). Conclusions: Applying NHAPA in addition to SRP improves clinical periodontal parameters more than SRP alone. Subgingival NHAPA may encourage clot adhesion to tooth surfaces by increasing surface wettability.
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