Elderly kidney transplant recipients have favorable outcomes but increased infection-related mortality

임정훈,Lee Ga Young,Jeon Yena,Jung Hee-Yeon,Choi Ji Young,CHO, JANG-HEE,Park Sun Hee,김용림,Kim Hyung-Kee,Huh Seung,유은상,Won Dong Il,Kim Chan-Duck 대한신장학회 2022 Kidney Research and Clinical Practice Vol.41 No.3

Background: The number of elderly patients with end-stage kidney disease has been increasing, but the outcomes of kidney transplants (KT) remain poorly understood in elderly patients. Therefore, we evaluated the clinical outcomes of elderly KT recipients and analyzed the impact of elderly donors. Methods: This retrospective cohort study included patients who underwent KT between 2000 and 2019. KT recipients were divided into four groups according to a combination of recipient and donor age (≥60 or <60 years); elderly recipients: old-to-old (n = 46) and young-to-old (n = 83); young recipients: old-to-young (n = 98) and young-to-young (n = 796). We compared the risks of mortality, graft failure, and acute rejection between groups using Cox regression analysis. Results: The incidence of delayed graft function, graft failure, and acute rejection was not different among groups. Annual mean tacrolimus trough level was not lower in elderly recipients than young recipients during 10-year follow-up. Mortality was significantly higher in elderly recipients (p = 0.001), particularly infection-related mortality (p < 0.001). In multivariable Cox regression analysis, old-toold and young-to-old groups had increased risk of mortality (adjusted hazard ratio [aHR], 2.89; 95% confidence interval [CI], 1.14– 7.32; p = 0.03; aHR, 3.06; 95% CI, 1.51–6.20; p = 0.002). However, graft failure and acute rejection risks were not increased in elderly recipients. Conclusion: In elderly recipients, graft survival and acute rejection-free survival were not inferior to those of young recipients. However, mortality, especially risk of infection-related death, was increased in elderly recipients. Thus, low immunosuppression intensity might help decrease mortality in elderly recipients.

적절한 용량 이하의 경구용 향응고제 사용 중 발생한 뇌출혈 환자의 임상 양상

조수진,황흥곤,나찬영,이영탁,최현배,조태구 世宗醫學硏究所 2000 世宗醫學 Vol.17 No.2

산발성 장형 위선암 환자의 Microsatellite Instability와 병리학적 양상

조창희,홍유찬,안지현,최경현,이상호,신영명,윤기영,정민정,장희경 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Background : Through many researches, microsatellite is expected to be a good diagnositic and prognostic factor in colorectal cancer, endometrial cancer, gastric cancer, and the others. The prevalence of microsatellite instability (MSI) in gastric carcinoma has reported variously, 13~44%. Purpose : We aimed to determine the prevalence of MSI-high and the relationship between MSI and pathological characteristics of sporadic intestinal type adenocarcinoma of stomach. Material and Methods : We analyzed 106 sporadic intestinal type adenocarcinoma specimens excised from patients who were over thirty-five years old to determine the statue of microsatellite by DNA sequencing. The tissues were formalin-fixed and paraffin embedded. DNA were extracted and amplified by polymerase chain reaction (PCR). MSI was determined using five markers recommended by National Cancer Institute (NCI). Specimens were also studied with five patholical factors-differenciation of tumor cells, depth of invasion, lymph node metastasis, vessel invasion, and perineural invasion- to determine pathological state. Result : The microsatellite statue was determined as MSI-High in 5 cases (4.7%), no MSI-low, and MSS (microsatellite stable) in 101 cases (95.3%). Within the frequency, there was no large gap in the distinction of gender in MSI cases, but in MSS cases, there was three-times more cases in male. MSI cases had moderate-to-poor differenciation and trend to invade toward serosa. All MSI cases showed no perineural invasion. But we could not find any statistical significance between MSI and pathological characteristics of sporadic intestinal type adenocarcinoma. Conclusion : Results suggest that MSI can not make any certain pathological significance in sporadic intestinal type adenocarcinoma. Even though less than 5% of sporadic intestinal type adenocarcinoma patients showed MSI, it can be used as a influential prediagnostic factor of gastric cancer. Further study with large scale of cases will be followed to verify these results.

진양호의 어류생산 개발에 관한 연구 : 제1보 진양호내에 서식하고있는 담수어류 분포상태 조사 Effect The investigation about the distribution state of inhabited fishes in Lake Jin-yang

조영래,진찬현 진주산업대학교 1973 論文集 Vol.11 No.-

The distrbution state of inhabited fishes in Lake Jin-yang Iocated in the west of Chinju city was investigated from marchl, 1972 to Octoben 31, 1972, and the resultu are follows. 1. In this investigation, 30 species, 23 Genus, 10 Family, 5 Order, I class, I phylum of fish are inhabited in Lake Jin-yang, order eyprinida of Family cyprinidae is dominant species with 60%. Fram the assumption of oxygen Consumption of the fish, about 5,000 tons per year of the common carp can be Produced in Lake Jin-yang. 2. Concerning the fish production in Lake Jin-yang. Carassius carassias ranked 57.3% and Gobiobotia naktongensis ranked 0.13% The main fishes are carassius carassius and cyprints-carpio if we make the use of the water temperatures in the bottom can be developed, trouts carp can be produced 3. Total lenth of inhabited fishes is 89,238 cm and the average lenth is 16.05 cm

자궁원발성 비호지킨 악성림프종 -3예 보고-

박찬필,고영혜,이중달,박문일,김경태,조삼현 대한병리학회 1995 Journal of Pathology and Translational Medicine Vol.29 No.3

雷雲內의 電荷分離 Mechanism에 關한 硏究

趙英男,柳承蘭,柳贊洙 조선대학교 사범대학 부설 교과교육연구소 1999 敎科敎育硏究 Vol.2 No.1

It is known that frictional rubbing between different ice surfaces causes electric charge separation, and Yoshida(1944) reported the colder ice was positively electrified. The mechanism of charge electric separation in thunderclouds is considered to be related to the friction or impact between ice crystal particles. In order to explain the mechanism for the electric charge separation in thunderclouds, the experiment was conducted. The results from that experiment through rubbing asymmetrically the artifially provided ice rods are as follows: Asymmetric rubbing was charged with effect of the temperature difference by a theory of thermoelectricity, when the colder ice was positively charged and the warmer ice negatively charged. The average difference of charge between them was 0.35volt. Opaque ice rod with air bubbles was chagred regardless of the effect of a theory of thermoelectricity. As the result of it, the cold ice rod was negatively charged and the effect of the friction was maximized by air bubbles. under a polarizing microscope, contact surface ice crystal cell was melted and frozen by the friction heat, and then was decreased in size. the charged volume was greatly increased at the colder range of -21℃∼-16℃ and was irregularly developed at warmer temperature region. the cooling apparatus made for experiment can be used in measuring the frictional charge generation.

정보통신산업 생산성 변화의 산업간 파급효과 분석

조영상,이정동,박찬수,김태유 한국생산성학회 2002 生産性論集 Vol.16 No.3

The Korean ICT industry is evolving at a dramatic speed, increasing its importance in the overall economy and producing numerous externalities on the other industries. The purpose of this srsearch is to investigate the productivity growth of Korean ICT industry and its effects on the other industries and to derive policy implications. For this purpose we perform inter-industry analysis. Inter-industry analysis is conducted to investigate how close co-relationship exist between ICT industry and other indrstries and to see how much ICT industry affects other industries. Our estimates of the productivity growth in the industry and its contribution to the overall korean Economy suggest the direct contribution of the ICT industry is significant, but its spillovers to the other industries are not so impressive. This implies that the link between ICT industry and other industries is weak and that most of the ICT products are used as final products and not as intermediate goods. We also find the high extent of import penetration in Korean ICT industry to be one of its major problems.

MSGC형 센서를 위한 제어시스템 및 영상 획득 S/W 개발

조진호,진경찬,채승표,박영식,김명남 경북대학교 센서기술연구소 1997 연차보고서 Vol.1997 No.-

열전대(thermocouple)를 이용한 Buchanan Plugger 표면의 온도상승 분석

조진숙,황윤찬,김선호,황인남,최보영,정영진,정우남,오원만 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.4

This study was performed to evaluate the actual temperature rise on the surface of Buchanan plugger using thermocouple. The heat carrier system 'System B Heatsource'(Model 1005, Analytic Technologies, Redmond, WA, USA) and the Buchanan pluggers of F, FM, M and ML sizes are used for this study. The temperature was set to 200℃ on digital display and the power level on it was set to 10. Five thermocouples were placed in direct contact with the surface of each size of Buchanan's pluggers at 1 mm increments from the tip to the 4 mm length of shank. The heat control spring was touched for 5 seconds, and temperature rise on the surface of the pluggers were measured at 1 sec intervals for more than 5 seconds with an accuracy of 0.01 using Data Logger. The data were statistically analyzed by one-way ANOVA. The results were as follows. 1. The position at which the temperature peaked was approximately at 1~2 mm far from the tip of Buchanan plugger (p<0.01). 2. The peak temperature was 215.25±2.28℃ in F plugger, 185.94±2.19℃ in FM plugger, 169.51±9.12℃ in M plugger, and 160.79±1.27℃ in ML plugger and the peak temperature was highest in F plugger and followed by, in descending order, FM plugger, M plugger. ML plugger showed the lowest peak temperature (p<0.01). 3. The temperature on the pluggers was decreased with the increase of touching time. This results suggest that the actual temperature on the surface of the pluggers dose not correlate well with the temperature set on digital display. Heat concentrates around the up. The larger plugger reveals lower temperature rise relatively.

Thermocouple을 이용한 Buchanan Plugger 표면의 온도상승 분석

조진숙,황윤찬,김선호,황인남,최보영,정영진,정우남,오원만 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.4

This study was performed to confirm the actual temperature rise on the surface of Buchanan plugger by evaluating the temperature rise on the surface of it, the peak temperature of pluggers of various size using thermocouple. The heat carrier system 'System B Heatsource' (Model 1005, Analytic Technologies, USA) and the Buchanan pluggers of F, FM, M and ML sizes are used for this study. The temperature was set to 200 which Dr. Buchanan's "Continuous wave of condensation" technique recommended on digital display and the power level on it was set to 10. The touch mode was used. Five thermocouples were placed in direct contact with the surface of each size of Buchanan's pluggers at 1 ㎜ increments from the tip to the 4 ㎜ length of shank. Each thermocouple was secured with cyanoacrylate adhesive and orthodontic resin block. The two wire leads of each thermocouple were connected to the appropriate channels of Data Logger. This was configured to simultaneously record input from the five thermocouples. The heat control spring was touched for 1, 2, 3, 4 and 5 seconds, and the temperature rise on the surface of the pluggers were measured at 1 sec intervals for more than 5 seconds with an accuracy of 0.01. Ten trials was determined for each plugger. The average of temperature rise and standard deviation was calculated for each size of plugger. The data were statistically analyzed by one-way ANOVA to determine their significance. The results as follows. 1. The position at which the temperature peaked was approximately at 1∼2㎜ far from the tip of Buchanan plugger (p<0.01). 2. The peak temperature was 215.25±2.28℃ in F plugger, 185.94±2.19℃ in FM plugger, 169.51±9.12℃ in M plugger, and 160.79±1.27℃ in ML plugger and the peak temperature was highest in F type and followed by, in descending order, FM type, M type. ML type showed the lowest peak temperature (p<0.01). This results suggest that the actual temperature on the surface of the pluggers does not correlate well with the temperature set on digital display. Heat concentrates around the tip. The larger plugger reveals lower temperature rise relatively.