심한 골병변으로 발현된 기능성 낭종성 부갑상선 선종

전숙,김영희,박지영,고관표,박철영,김덕윤,우정택,김성운,김진우,김영설,고석환 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.2

낭종성 부갑상선 선종과 심한 골병변을 동반한 부갑상선 기능항진증은 매우 드문 질환으로서, 저자들은 양측 고관절의 통증을 초기 주소로 내원한 환자에서 고칼슘혈증과 부갑상선 호르몬 증가, 골병변의 방사선적 소견을 통해 부갑상선 기능항진증을 진단하고, 경부 초음파와 컴퓨터 단층 촬영, 부갑상선 스캔검사 및 수술중 부갑상선 낭종액 검사 등을 통해 기능성 부갑상선 낭종의 한 종류인 낭종성 부갑상선 선종을 진단하고 수술적 제거를 통하여 정상화된 1예를 경험하였다. A cystic parathyroid adenoma is rare. A case of primary hyperparathyroidism, with the cystic formation of a parathyroid adenoma and a severe bony lesion, is reported. A 52-year-old male was admitted due to pain in both hips and for evaluation of hypercalcemia. The plasma level of the intact parathyroid hormone (iPTH) was elevated to 1424 pg/mL. Ultrasonography and the computed tomography revealed a parathyroid cyst on the left thyroid lower pole. Parathyroid scintigraphy detected a parathyroid adenoma. A radiograph showed a subperiosteal bone resorption on the phalanges, and a brown tumor (osteitis fibrosa cystica) on the femur shaft was noted. A surgical excision of the parathyroid adenoma was performed. The PTH level in the cystic fluid was increased. A histological examination confirmed a cystic parathyroid adenoma. The PTH level was normalized after the operation (J Kor SOC Endocrinol 18:214-220, 2003).

전이성 뇌종양에 대한 고식적 방사선치료의 결과

고영삼,오윤경,남택근 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Background and Obiectives : To evaluate the role of palliative radiotherapy in the treatment of metastatic brain tumor with respect to response, survival and prognostic factors, retrospectively Materials ðods : From Jan 1998 to Jan 2003, a total of 57 patients diagnosed as metastatic brain tumor were referred for palliative radiotherapy Of them, forty-four patients were eligible for this study. The most common primary tumor was lung cancer in 31 patients (70.5%). A total doses of 27.5-40.0 Gy were delivered to whole brain with daily doses of 2.0-3.0 Gy To evaluate the treatment response, all patients were evaluated by neurological functional classification prior to and after radiotherapy Results : The positive response was noted in 36 patients (81.8%) and 8 patients (18.2%) did not improve. The median survival time of all patients was 6 months. 1-and 2-year survival rates were 17.4% and 2.9%, respectively. The median survival time of patients younger than 60 vs older were 9 vs 4 months (p=0.009), respectively. The median survival time of patients with stable vs progressive vs unknown primary status were 9 vs 4 vs 5 months (p=0.003), respectively Multivariate analysis showed that age and primary tumor status were independently significant prognostic factors affecting survival. Conclusion : The radiotherapy could relieve neurological symptoms effectively and promptly in most patients and prolong survival of patients. The most significant factors affecting survival were age and primary tumor status, and therefore more definitive treatment modality including surgical resection or radiosurgery should be considered in the patients with favorable prognostic factors.

일 도농복합지역 저소득층 노인의 건강문제 분석 : 보건소 방문간호사업 대상자 중심으로

고일선,,이태화,이경자,이정렬,임미혜,천의영,주윤미,이계철 노인간호학회 2005 노인간호학회지 Vol.7 No.2

Purpose: The purpose of this study was to analyze the health problems of low-income aged with chronic illness living in urban-rural composite area. Method: The sample consisted of 440 aged who were receiving home care services from a public health center. MDS-HC was applied to analyze the health problems of the aged. Data were collected through a face- to-face interview by six trained interviewers from June 28 to July 15, 2004. Result: Subjects had average number of 8 health problems in both urban and rural area. Lack of preventive health care measure, pain, and visual function were the most frequent health problem. The rural aged had more pain, bowel management problems, compared to the urban aged having more urinary incontinence and indwelling catheter. There were many health problems related to falls and pressure ulcers with middle-old aged in urban, and old-old aged in rural area. Conclusion: The results of this study showed strategies for care intervention of low-income elderly to put in practice. Therefore, tailored-service for each subject should be provided.

TRANSPALATAL LINGUAL ARCH에 의한 골내 응력 분포에 관한 광탄성적 연구

고기영,태기출,국윤아,김상철 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.5

본 연구는 TMA wire로 제작된 transpalatal lingual arch에 의한 골내 응력 분포를 파악하기 위하여 양측성 및 편측성 확장을 가하여 이때 발생하는 치아주위조직 응력 분포 양상을 광탄성 응력해석법으로 관찰하여 다음과 같은 결과를 얻었다. 1. 양측성 확장시 수평 변형만 적용했을 때 탄선끝이 각진 경우 둥근 탄선끝을 적용한 경우보다 응력이 치근단으로 집중되며 회전중심을 의미하는 흑색선이 변화하는 양태를 보였고 수직변형량이 증가되면서 전체적인 응력차수의 증가와 흑색선의 하방 이동 양상을 보였다. 2. 편측성 확장을 위해 수평 변형과 함께 확장측에만 수직 변형을 적용하였을 때 확장력이 확장측으로 편중되는 응력분포를 관찰할 수 있었다. 수직 변형량의 증가시 확장측 구치는 정출하는 응력을 보였고 수평변형량의 증가시 고정측치아도 경사지려는 응력분포가 관찰하였다. 3. 편측 구치의 회전을 개선하기 위해 철사끝을 비대칭적으로 toe-in한 경우 변형량이 적은 구치의 치근단 원심측에 응력분포를 관찰할 수 있었다. 4. 악궁 확장시 철사의 길이를 줄일수록 무늬차수가 증가하는 응력 분포를 보였다. The purpose of this study was to investigate the stress distribution and intensity derived from the transpalatal lingual arch in the investing bone composed of photoelastic material(PL-3). The transpalatal lingual arch wire was deflected in the horizontal and vertical direction to give the various conditions. The two-dimensional photoelastic stress analysis was performed, and the stress distrebution was recored by photography. The results were as follows: 1. In bilateral expansion, as horizontal deflection was singly applied, the stress was more concentrated on the root apex in square free end than round. In square free end, as vertical deflection was increased gradually, the black line meaning center of rotation moved inferiorly together with the increment of whole fringes. 2. In application of vertical deflection on anchorage side for unilateral expansion, the stress distribution that expansive force leaned to expansion side was observed. As vertical deflection increased, the extruding stress was observed on molar of expansion side. And as horizontal deflection increased, the tipping stress on the molar of anchorage side was observed. 3. In unilateral rotation with the asymmetric toe-in, the fringe appeared on the distal aspect of root apex.

직장 내 Probe 삽입이 내요도 괄약근 개방에 미치는 영향

고현윤,박병규,차영훈,박호준 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.6

상악확장술 치료효과의 메타분석 : 견치간 폭경과 대구치간 폭경 확장의 비교 및 급속과 완속 확장의 비교 comparison of intercanine/intermolar expansion and rapid/slow expansion

고창희,임성훈,윤영주,김광원 대한치과교정학회 2004 대한치과교정학회지 Vol.34 No.1

본 연구의 목적은 다수의 연구들로부터 추출한 각각의 결과를 체계적이고 객관적인 방법으로 병합, 개관하는 통계분석법인 메타분석을 이용하여 상악확장술에서의 견치간 폭경과 대구치간 폭경의 확장 및 급속과 완속 확장에서의 확장량과 재발량을 비교하는 것이었다. 메드라인 검색을 통해 1979년부터 2000년까지의 문헌들 중 사람을 대상으로 상악확장술의 효과에 관해 조사한 문헌 388개를 찾은 후 논문 선택 및 제외 범주에 따라 최종적으로 7개의 문헌을선정하여 메타분석을 시행하여 다음과 같은 결과를 얻었다. 1. 상악확장술에 의한 상악 제 1대구치간 폭경은 평균 6.0mm의 확장되었으며, 보정 후 측정에서 평균4.8mm가 유지되어 평균 20.0%(1.2mm)의 재발경향을 보였다. 2. 상악 견치간 폭경은 제 1대구치간 폭경의 확장보다 2.3mm적은 평균 3.7mm 확장되었으며, 보정 후 측정에서 평균 2.6mm가 유지되어 평균 29.7%(1.1mm)의 재발경향을 보였다. 3. 급속 상악확장술과 완속 상악확장술의 치료효과의 차이는 확장량과 보정 후 재발량 및 유지량에서 6% 미만(0.1-0.3mm)이었다. 그러나 상악 견치간 및 제1대구치간 폭경 변화에 있어서 두 방법 간에 골격성 및 치성 확장량의 비율에서 차이가 있을 수 있다. As a research method that weighs and combines evidence, meta analysis produces evidence that is more powerful than the original studies. The purpose of this study was to compare the intercanine/intermolar expansion and rapid/slow expansion in the maxillary expansion treatment using meta analysis. Medline was searched from 1979 to 2000 for all studies examining the stability of transverse expansion of the human maxilla, and 388 articles were found. Then these articles were reduced to 7 based on the defined inclusion and exclusion criteria, and a cumulative Meta evaluation score was computed for each study. The results were as follows; 1. The mean expansion in intermolar width was 6.0mm. Of the 6.0mm, 4.8mm was retained and 20.0%(1.2mm) was relapsed while wearing retainers. 2. In intercanines width, the mean expansion was 3.7mm. Of the 3.7mm, 2.6mm was retained and 29.7%(1.1mm) was relapsed while wearing retainers. 3. The differences in the amount of expansion and relapse between rapid expansion group and slow expansion group were less than 6%(0.1-0.3mm). But, there might be differences in the skeletal/dental exapnsion ratios according to the expansion method.

수중불분리 콘크리트의 부착특성에 관한 실험적 연구

장일영,고용득,윤영수 金烏工科大學校 1996 論文集 Vol.17 No.-

An experimented study was carried out for the estimate of the bond strength property of underwater non-segregation concrete. The action of bond force and slip are affected by various factors. Bond is made up of three components of chemical adhesion and friction, mechanical interaction between concrete and steel. But properties of underwater non-segregation concrete is different from other type of concrete. This study addresses the comparison of physical properties of concrete according to the use of different cement types. It is also recommended to select a proper cement type depending on structural characteristics. Rational analytic formula for the modulus of rupture and bond stress are to be predicted from compressive strength of concrete.

γ-Poly(glutamic acid) 분해 세균의 분리 및 동정

허윤희,고영환 제주대학교 환경연구소 1998 환경연구논문집 : 제주대 Vol.6 No.-

r-poly(glutamic acid) (r-PGA) was produced in the culture filtrate of Bacillus licheniformis 9945a. It is a water soluble and naturally derived polyamide consisted of glutamic acid repeating units that are linked between the a-amino and r-carboxylic acid functionalites. It is the mapr composition of the capsular substances from Bacillus species. r-PGA is not toxic to human health and biodegradable. It has a potential to be used in the field of medicine, artificial human organ, food additives, plastic manufacture and oil industry. Even though its production has been studied steadily, few research reports concerning its biodegradation have appeared. Few informations about depolymerizing enzyme, degradation mechanism and organisms, which are necessary for industrial applications, are available. The principal purpose of this study was to isolate and identify a r-PGA degradmg bacterium from fermented soy paste. Eight strains from soy paste were isolated and 3 of those apparently decreased the viscosity of the culture filtrate with r-PGA. The isolate No. 5 which decreased most rapidly the viscosity of the culture with r-PGA was chosen and identified. The isolate No. 5 was very similar to Bacillus licheniformiis and Bacdlus pumilus according to the keys in Bergey's Mannual of Systematic Bacteriology. The fatty acid composition of the bacteria also confirmed its identity as Bacillus species. According to MIDI program the isolate No. 5 showed 91.8% similarity to Bacillus licheniformis.

1993년에 유행한 무균성 뇌막염 : 서울지역 소아를 대상으로 The study of pediatric patients in Seoul, with the emphasis on the isolation of causative agent

문형남,고태성,박영서,박윤아,홍창희 울산대학교 의과대학 1994 울산의대학술지 Vol.3 No.1

From May to July 1993, we observed an epidemic of aseptic meningitis. We performed clinical and virological studies on 174 children with aseptic meningitis who had been admitted to the Department of Pediatrics, Asan Medical Center, from May to July, 1993 The results were as follows; 1) This epidemic of aseptic meningitis was most prevalent in June 1993. The most of the patients were 3 to 6 years old and male to female ratio was 1.6 : 1. 2) The most patients suffered from fever, vomiting, headache, and abdominal pain was noticed in 36% of patients, characteristically. 3) In 7 cases among 10 randomly sampled cases, enterovirus was cultured. Among them, we performed serotyping in 3 cases and Echovirus 9 was isolated.

척추손상 쥐의 지방유래 줄기세포와 미노사이클린의 운동기능 회복효과

장재혁,고현윤,차영선,박형욱,신용범,손현주 부산대학교 병원 암연구소 2009 부산대병원학술지 Vol.- No.25