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인슐린 비의존형 당뇨병 환자에서 혈장 Endothelin-1농도의 변화
신양수,조희충,김원식,국기용,김용화,정종훈,문철웅,배학연,양성훈 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2
Endothelin(ET) is a 21-residue peptide originally isolated from the cultured porcine endothelial cells. There are at least three genes for endothelin:endothelin-1(ET-1), endothelin-2(ET-2), and endothelin-3(ET-3). Endothelins are present in various human biological fluids including plasma, urine, breast milk, and saliva and have been found elevated plasma ET concentrations in patients with diabetes mellitus, Patients undergoing maintenance hemodialysis due to chronic renal failure, patients with acute myocardial infarction, and patients with subarachnoid hemorrhage. Endothelial cell damage is suspected to occur in diabetic patients and may be one important cause of angiopathy, a major complication in diabetes mellitus. The elevation of ET in diabetic patients may be a marker of, and further exacerbate, their vascular disease. We measured the levels of ET-1 in plasma of 50 patients with non-insulin dependent diabetes mellitus(NIDDM) and 25 normal subjects by radioimmunoassay. The plasma ET-1 concentration (mean±S.D.) in NIDDM was 6.461 A2.510 f㏖/ ㎖, and was significantly higher than in normal subjects (4.567±1.155f㏖/㎖) (P<0.05). The plasma ET-1 concentration (mean±S.D.) in diabetic retinopathy group( 7.15±2.454 f㏖/ml) was significantly elevated than those in otherwise uncomplicated groups (5.348±2.390 f㏖/㎖)(P<0.01). The correlation between any clinical parameters and plasma ET-1 levels in NIDDM was not significant, In conclusion, this study suggest that the elevated levels of ET-1 in diabetic patients may be play a important role in the pathogenesis of diabetic complications.
이신재,안석준,백승학,김태우,장영일,양원식,서정훈,남동석 대한치과교정학회 2002 대한치과교정학회지 Vol.32 No.4
교정치료와 악교정 수술을 필요로 하는 환자가 점증하는 현 시점에 비추어, 이에 대한 기술적인 측면의 발전과는 달리 수술-교정 치료 환자에 대한 정신사회학적 혹은 정신심리적 양상에 대한 객관적인 정보는 그리 많은 주목을 받는 편이 아니었다. 수술-교정치료는 과학적인 치료과정이긴 하지만, 어느 정도 심미적 혹은 예술적인 측면을 지니는 선택 치료의 면모를 지닌다. 그러므로 치료에 대한 환자의 주관적인 느낌은 치료 기술이나 치료의 의학적 성공 여부보다 더 큰 영향을 미칠 수 있다. 그러므로, 수술-교정 (혹은 교정) 치료에 대한 환자의 반응을 예측하기 위한 정신심리적인 정보는 치료에 유용한 지표가 될 수 있다고 가정할 수 있다. 통제 소재에 대한 연구는 인간의 다양한 행동을 예측하기 위한 유용한 지표로 알려져 왔는데, 본 연구에서는 42명의 수술-교정치료 환자와 성별/연령별로 표본 추출된 42명의 통상적 교정치료 환자를 대상으로 삼아 정신=심리적 비교 및 분석의 방법으로 두 가지 종류의 내외 통제 소재(internal/external locus of control) 검사를 시행하였다. 그 결과 수술-교정치료군에서만 남자가 여자에 비하여 낮은 외적 통제(높은 내적 통제)의 경향을 보였다. 결론적으로 수술-교정치료 환자의 정신심리적 기반은 성형 수술 환자와는 달리 교정치료 환자와 유사한 경향을 지닌 것으로 생각되었다. Surgical-orthodontic treatment is an increasingly more common dental procedure whose unique psycho-social or psychological feature has not been fairly quantified objectively. Since the treatment of a surgical-orthodontic (or orthodontic) patient is part science and part art, a subjective recognition of a patient about his or her own treatment may be more important than technical success during and after treatment. Therefore, the knowledge of the patient''s underlying psychological status could be useful in the prediction of patient's response to surgical-orthodontic (or orthodontic) treatment. The purpose of this study was to investigate and evaluate the psychological difference between conventional orthodontic patient and surgical-orthodontic patient by using locus of control (LOC) examination. Locus of control scale has been proven to be extremely useful in the prediction of a variety of human behaviors. Two types of locus of control data (I-score, Internal locus of control score ; E-score, External locus of control score) were obtained for 42 surgical-orthodontic patients and randomly selected 42 conventional orthodontic patients (as a control group) matched for age and gender. No statistically significant difference was observed in the scale of internal and external locus of control between the groups of surgical-orthodontic patients, males showed lower E-score (external locus of control score, higher internal locus of control tendency) than females. The results of this study suggested that the psychological background of surgical-orthodontic patients, in contrast with that of cosmetic surgery patients, has a similar disposition with that of orthodontic patients.
김동규,김규태,이상조,신형식,김학양,유재영,배수동,임성희,김병태,김종혁,송숙희 대한내과학회 1991 대한내과학회지 Vol.41 No.5
Primary aldosteronism is a condition in which chronic aldosterone excess exists independently or semiindependently of the renin-angiotensin system, resulting in hypertension and hypokalemia. The most common cause of primary aldosteronism is unilateral aldosterone-producing adrenal cortical adenoma. The indiopathic aldosteronism showing bilateral adrenocortical hyperplasia accounts for the bulk of the remaining cases. Only rare cases of primary aldosteronism are known to be due to multiple aldosterone-producing adrenocortical adenoma. We report a case of primary aldosteronism due to bilateral adenomas, which was diagnosed preoperatively by abdomen CT and then confirmed by operation and pathological findings.
고양이에서 실험적 급성신부전이 Mivacurium의 근이완 작용에 미치는 영향
최미영,김정렬,김지응,심규대,신양식 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.32 No.6
Background : Mivacurium is mainly metabolized by plasma cholinesterase. However, the duration of action may be changed in various conditions such as liver dysfunction. To evaluate the action duration and recovery of mivacurium under the experimental acute renal failure, the pharmacodynamic studies were done. Methods : The pharmacodynamic studies were done using a common peroneal nerve-anterior tibialis muscle preparation in 12, either sex, adult cats(weight 2.0∼4.0 kg). The acute renal failure was made by the ligation of bilateral renal pedicles 1 hour prior to the pharmacodynamic study. All the cat received 5×ED95 of mivacurium. The action durations and recovery indices were measured. And plasma cholinesterase activities were measured at each event. Results : The duration of mivacurium was not prolonged with acute renal failure group(17.20 5.48 min.) compared to control group(13.48 4.30 min.). The recovery indices were not increased in the acute renal failure group(3.56 0.58 min.) as compaired with the conol group(2.82 0.99 min.). Conclusions : The mivacurium-induced neuromuscular blockade is not prolonged by the experimental acute renal failure. (Korean J Anesthesiol 1997; 32: 874∼878)
신장식(Shin, Jang-Sik),박종원(Park, Jong-Won),양혜경(Yang, Hye-Kyong),이승영(Lee, Seung-Young),성봉현(Song, Bong-Hyun),신석재(Shin, Seock-Jae) 한국신재생에너지학회 2006 한국신재생에너지학회 학술대회논문집 Vol.2006 No.11
In this study, we investigated operating characteristics of the LNG burner for steam methane reforming. The developed LNG burner and catalytic reactor to supply an efficient heat transfer between the combustion gas and catalyst got a good response of various operating load within 5-7 minute and high efficiency for steam methane reforming as a conversion of methane over 90%. We calculated the volume of catalyst for 1Nm³/hr steam LNG reforming as 211cc/(Nm³/hr;H₂) and got the operating condition and design data of the burner and steam reforming for LNG.
Clinical Significance of Anti - endothelial Cell Antibody in Renal Transplant Recipients
(Young Shin Shin),(Chul Woo Yang),(Hee Jong Ahn),(Cheol Whee Park),(Dong Chan Jin),(Yong Soo Kim),(Yoon Sik Chang),(Byung Kee Bang) 대한내과학회 2001 The Korean Journal of Internal Medicine Vol.16 No.1
N/A In order to evaluate the role of anti-endothelial cell antibody (AECA) in acute rejection in renal transplantation, serum AECA IgG titers were measured in 68 healthy controls, 111 chronic hemodialysis (HD) patients and 58 first renal transplant recipients. The AECA titer in hemodialysis patients was higher than in healthy controls (13.9±5.0 vs. 4.8±2.3 U/mL, p<0.01). In transplant recipients, AECA titers were not affected by dialysis mode (HD vs. CAPD vs. non-dialysis ; 9.6±7.6 vs. 7.9±3.9 vs. 11.9±3.1 U/mL, p>0.05). After renal transplantation, AECA titer was decreased significantly (vs. 4.7±3.6 U/mL, p<0.01). The serum AECA IgG titers increased significantly in recipients with acute rejection (6.9±3.1 vs. 13.5±9.9 U/mL, p<0.01), but decreased to 5.6±3.0 U/mL (p<0.01) after formal rejection therapy. In the recipients with acute rejection (n=27), the pre-renal transplant AECA titer was higher than in that without acute rejection (14.0±8.6 vs. 7.7±3.8 U/mL, p<0.01). The results of this study lead us to conclude that pre- and post-renal transplant AECA titer might be a useful predictor for acute rejection and useful for monitoring acute rejection in renal transplant recipients.
A New Lodging Tolerant and High-Yielding Glutinous Rice Cultivar "Dongjinchalbyeo"
Mun Sik Shin,Hyun Tak Shin,Jae Kil Lee,Kyu Seong Lee,Bo Kyeong Kim,Jae Kwuon Ko,Tae Hwan Noh,Ki Yong Ha,Young Doo Kim,Bo Kap Yang,Yang Ho Oh,Chong Seok Kim,Seung Yeob LeeHyun 한국육종학회 2003 한국육종학회지 Vol.35 No.4
“Dongjinchalbyeo” is a new japonica glutinous rice cultivar developed from a cross between Milyang95 and SR11155-4-2/Toyonishiki by the rice breeding team of the National Honam Agricultural Experiment Station (NHAES), RDA, in 1998. This cultivar has a sho
가정용 연료전지 1Nm³/hr급 천연가스 연료처리장치의 운전 특성
신장식(Shin, Jang-Sik),신석재(Shin, Seock-Jae),이승영(Lee, Seung-Young),양혜경(Yang, Hye-Kyong),성봉현(Sung, Bong-Hyun),김두훈(Kim, Doo-Hoon),박종원(Park, Jong-Won) 한국신재생에너지학회 2007 한국신재생에너지학회 학술대회논문집 Vol.2007 No.11
In this study, we investigated operating characteristics of natural gas fuel processor for polymer electrolyte membrane fuel cells (PEMFCs). The fuel processor consists of a natural gas reformer, a water-gas shift reactor, a heat-exchanger and a burner, in which the overall integrated volume is exactly(exceptionally) small, namely, about 10L except outer insulation. The producted hydrogen is 1Nm³/hr and the maximum thermal efficiency is {sim}76%(low heating value) at full operating load. A compact and highly efficient 1Nm³/hr class natural gas fuel processor was developed at UNISON is an advantage for application in residential PEMFCs co-generation systems.