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Woon Goo Ha(河雲龜),Hak Soo Suh(徐學洙) 한국육종학회 1993 한국육종학회지 Vol.25 No.2
In order to evaluate the Korean red rices as useful germplasm, ten lines of long grain red rices and ten lines of short grain red rices were tested for flowering characters such as rate of opened floret, angle of opened floret, duration of anthesis and stigma exsertion rate. Rate of opened floret of the red rices was higher than that of cultivars Seomjinbyeo and Samgangbyeo. Angle of opened floret and duration of anthesis of the short grain red rices were significantly higher and longer than those of cultivated variety Seomjinbyeo, however those of the long grain red rices were almost same as those of the cultivated variety Samgangbyeo. Stigma exsertion rate of the red rices was mostly higher than those of the cultivars Seomjinbyeo and Samgangbyeo. Thus flowering characters of the red rices appeared to be more effective for outcross than cultivars.
Pyrolysis kinetics of coking coal mixed with biomass under non-isothermal and isothermal conditions
Jeong, Ha Myung,Seo, Myung Won,Jeong, Sang Mun,Na, Byung Ki,Yoon, Sang Jun,Lee, Jae Goo,Lee, Woon Jae Elsevier 2014 Bioresource technology Vol.155 No.-
To investigate the kinetic characteristics of coking coal mixed with biomass during pyrolysis, thermogravimetric (TG) and thermo-balance reactor (TBR) analyses were conducted under non-isothermal and isothermal condition. Yellow poplar as a biomass (B) was mixed with weak coking coal (WC) and hard coking coal (HC), respectively. The calculated activation energies of WC/B blends were higher than those of HC/B blends under non-isothermal and isothermal conditions. The coal/biomass blends show increased reactivity and decreased activation energy with increasing biomass blend ratio, regardless of the coking properties of the coal. The different char structures of the WC/B and HC/B blends were analyzed by BET and SEM. (C) 2014 Elsevier Ltd. All rights reserved.
B cell-associated immune profiles in patients with end-stage renal disease (ESRD)
Kim, Kyoung Woon,Chung, Byung Ha,Jeon, Eun Joo,Kim, Bo-Mi,Choi, Bum Soon,Park, Cheol Whee,Kim, Yong-Soo,Cho, Seok-Goo,Cho, Mi-La,Yang, Chul Woo Korean Society for Biochemistry and Molecular Bion 2012 Experimental and molecular medicine Vol.44 No.8
Most of the previous studies on immune dysregulation in end-stage renal disease (ESRD) have focused on T cell immunity. We investigated B cell subpopulations in ESRD patients and the effect of hemodialysis (HD) on B cell-associated immune profiles in these patients. Forty-four ESRD [maintenance HD patients (n = 27) and pre-dialysis patients (n = 17)] and 27 healthy volunteers were included in this study. We determined the percentage of B cell subtypes, such as mature and immature B cells, memory B cells, and interleukin (IL)-$10^+$ cells, as well as B cell-producing cytokines (IL-10, IL-4 and IL-21) by florescent activated cell sorting (FACS). B cell-associated gene expression was examined using real-time PCR and B cell producing cytokines (IL-10, IL-4 and IL-21) were determined using an enzyme-linked immunosorbent assay (ELISA). The percentage of total B cells and mature B cells did not differ significantly among the three groups. The percentages of memory B cells were significantly higher in the pre-dialysis group than in the HD group (P<0.01), but the percentage of immature B cells was significantly lower in the pre-dialysis group than in the other groups. The percentages of IL-10-expressing cells that were $CD19^+$ or immature B cells did not differ significantly (P>0.05) between the two subgroups within the ESRD group, but the serum IL-10 concentration was significantly lower in the pre-dialysis group (P<0.01). The results of this study demonstrate significantly altered B cell-associated immunity. Specifically, an imbalance of immature and memory B cells in ESRD patients was observed, with this finding predominating in pre-dialysis patients.
이한식,하영록,구홍두,장석준,심호식,김승환,이정운 대한응급의학회 1996 대한응급의학회지 Vol.7 No.2
Objective : Tetanus decreased in prevalence since the systemic vaccination began in 1940s. Despite of the improvement in treatment like critical care with ventilatior or antibiotics, the mortality rate resides around 45%. Currently the tetanus prevention protocol recommends immunization in infancy and boosters every tenth years. Thereafter the immunization with toxoid only or toxoid plus immunoglobulin injections is recommended according to the type of injury. In most of ED in Korea, only tetanus immunoglobulin is given without any basis. Previously we proved the effect that passive immunization with the immunoglubulin 250 IU last long for only a month. At this time we measured the effect of the active immunization with toxoid and its effect was compared to the effect of the tetanus immunoglobulin to find out the logical tetanus prevention after an injury. Method: 20 healthy adult volunteers were injected with tetanus toxoid and their anti-tetanus antibody titers measured before the injection, 1 week and 4 weeks after the inection. No volunteers have taken any medication for chronic illness(e.g. hepatits, tuberculosis) or had an tetanus immunization or booster in the last 6 months. Antibody titers were measured by IMMUNOZYM??-TETANUS and t-test was performed on the results, Results: 1. Total 20 volunteers(12 males and 8 females) were participated. 2. Subjects` ages were 21 to 44 years old and there were no relevance to the antibody titer. 3. The antibody titers of before the anti-tetanus toxoid injection and 1 week, 4 weeks after the injection revealed significant difference and the antibody titers of the first and the forth week after the injection also showed a significant difference. Conclusion: Currently in Korea, the tetenus immunoglobulin 250 IU given alone as tetanus prevention was injected, but it did not elevate the anti-tetanus antibody titer for 4 weeks where as tetanus toxoid injected intramuscularly did significantly. Therefore, tetanus toxoid should be given on the dirty injuries with additional tetanus immunoglobulin injection to accomplish the correct method of tetanus, tetanus toxoid prevention.
김옥준,하영록,최옥경,심호식,장석준,정성필,이경룡,박인철,김승환,구홍두,이정운 대한응급의학회 1994 대한응급의학회지 Vol.5 No.2
Despite the progress in treatment modality, tetanus still has a high mortality rate. However, the morbidity of tetanus can be decreased through proper prophylactic measures. Although Center for Disease Control(CDC) recommands Td or Td/TIG injection depending on prior immunization state and wound character, TIG alone is being injected to patient with open wound for tetanus prophylaxis in Korea. Therefore, we studied antitetanus antibody titers after injecting 250IU of TIG to evaluate TIG's duration of immunization effect, in vivo. TIG 250IU was injected to 42 healthy adult volunteers and their antitetanus antibody titers were measured at prior to TIG injection, 1 week and 4 weeks after infection. Antibody titers were measured by using ELISA assay with IMMUNOZYM-TETANUS and their results were verified by using the standard t-test. Mean antitetanus antibody titers were 0.167±0.031IU/mL, 0.211±0.031IU/mL and 0.186±0.031IU/mL at before injection, 1 week and 4 weeks after injection, respectively. Antibody titers showed significant difference between values at before injection and 1 week after injection. However, no difference was found between the values before injection and 4 weeks after injection. The practice of injecting TIG 250IU alone for prophylaxis has little effect on maintaining an increased antitetanus antibody titer until 4 weeks after injection.
급성 척수손상 환자의 치료 : 최근의 세포치료 연구 결과를 중심으로
윤도흠,하윤,윤승환,김은영,현동근,박종운,박소라,구성욱,김긍년,조용은,박형천 대한척추신경외과학회 2004 Neurospine Vol.1 No.1
A therapy to treat injuries to the central nervous system is, to date, a major clinical challenge. The devastating functional consequences they cause in patients have encouraged many scientists to search, in animal models, for a repair strategy that could, in the future, be applied to humans. To highlight the current understanding of traumatic spinal cord injury, we provide information regarding state-of-the-art care for the acute spinal cord injured model, and explore future treatments aimed at neural preservation and reconstruction. This article also reviews recent phase I clinical trials in neural and nonneural cell transplantation, stressing that the transition from basic science to clinical applications.