Glassy Carbon 전극에서의 벗김 전압-전류법을 이용한 2-Amino-1-cyclopentene-1-dithiocarboxylate의 분석과 전극 반응 메카니즘의 연구

沈允輔,朴德洙,崔星洛,元美淑 부산대학교 기초과학연구소 1988 부산대학교 기초과학연구소 연구논문집 Vol.8 No.-

많은 금속이온들에 대한 킬레이트시약으로 알려진2-amino-1-cyclopentene-1-dithiocarbox-ylate(acdc) 음이온의 전기화학적 거동을 직류 폴라로 그래피, 순환 전압전류법 및 양극 벗김 전압 전류법을 사용하여 수용액 및 아세톤 용액에서 각각 조사하였다. 수용액에서 glassy carbon전극을 사용하였을 때 +0.25V vs. SCE에서 1전자 산화반응을 거쳐 acdc의 이합체가 생성됨을 확인하였으며 이 이 합체는 glassy carbon 전극 표면에 석출되어 흡착이 일어남을 알 수 있었다. 이 흡착된 이합체가 +0.80V에서 2전자 산화반응을 거쳐 S가 한원자 유리된 고리를 형성하는 반응이 일어 남을 알았다. 이러한 이합체 생성반응을 이용하여 이 화합물의 흡착성 양극 벗김 전압전류법에 의한 분석법을 조사하였다. 직류폴라로그래피을 사용한 벗김 전압-전류법에 의해 검량선을 얻은 결과 3 ×10^(-5)M∼10^(-6)M 사이에서 좋은 직선상을 얻을 수 있었으며 확산전류를 사용한 분석법에 비해 약100배 가량 분석감도가 증진됨을 알 수 있었다. 이때 검출한계는 2.5 ∼10^-7)M이었으며 5 ×10^(-6)M에서의 상대 표준편차는 ±4.1%이었다. The electrochemical behavior of 2-Amino-1-cyclopentene-1-dithiocarboxylate(acdc) was investigated by the use of polarography, cyclic voltammetry and cathodic stripping voltammetry at glassy carbon electrode. In this study, it was found that the dimer of the acdc was deposited on the glassy carbon electrode via one-electron oxidation process at ±0.25V vs.SCE. The ring formation between two dithio group occurs along with the elimination of one sulfur atom. The elimination of sulfur atom occurs via two electron oxidation process at ±0.8V vs.SCE. The most sensitive cathodic stripping peak due to the formation of the dimer was observed at -0.85V vs. SCE. The peak relationship between current and concentration was fairly linear in the range of 3 ×10^(-5)∼1.0 ×10^(6)M. The preconcentration procedure enhanced the sensitivity about 100 times for the analysis of acdc using diffusion current. Detection limit was found to be 2.5 ×10^(-7)M and relative standard deviation was ±4.1% at 5.0 ×10^(-6)M DC polarography.

RHEED장치의 제작 및 특성과 이를 이용한 반도체의 표면연구

박종윤,정재인,이경원,이덕원 성균관대학교 기초과학연구소 1987 論文集 Vol.38 No.2

표면구조 분석장치의 하나인 RHEED(Reflection HIgh Energy Electron Differaction) 장치를 제작 하였다. 전자총 부분은 관례적인 전자 현미경과 유사하나 진공 봉입 부분이 특별히 유리로 만들어 졌다. 전자 빔은 자기 렌즈로 접속 시켰으며 빔의 발산은 대략 1×10exp(-3) rad이었다. 실험은 초고진공상자 내에서 행하였으며 이를 이용하여 Si(111)와 CdS 단결 정의 RHEED 패턴을 얻어서 이론적으로 계산한 것과 비교 하였다. RHEED(Reflection High Energy Electron Diffraction) apparatus which is one of the systems of surface structure analysis has been constructed. Electron gun is similar to that of conventional electron microscope except that a vacuum seal part is specially made of glass. Electron beam is focused by means of magnetic lens, and the beam divegence is about 1×10exp(-3)rad. The experiments were performed in UHV system. With this apparatus we obtained RHEED patterns from single crystasls of Si(111) surface and CdS cleaved surface and compared the patterns with those calculated theoretically.

한국형 기분장애 질문지의 타당화 연구

전덕인,윤보현,정한용,하규섭,신영철,박원명 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.5

Objectives : This study aims to test the validity of the Korean version of Mood Disorder Questionnaire (K-MDQ), a Screening instrument for bipolar disorder. Methods : A total of 238 subjects (126 DSM-IV bipolar outpatients and 112 controls without psychiatric history) completed the K-MDQ. Results : The Cronbach's alpha, used to measure the internal consistency of the scale, was high (0.88). Principal component analysis with varimax rotation revealed three factors, which explained 59.5% of the variance. Individual item correlations with the total score were all statistically significant (p<0.001). The mean total score of the K-MDQ was 8.48 in bipolar disorder and 4.51 in non-clinical participants. A total K-MDQ score of 7 or more excluding further two questions was chosen as the optimal cutoff, as it provided good sensitivity (0.75) and specificity (0.69). Conclusion : The results of this study showed adequate validity of the K-MDQ, suggesting that this instrument is useful for screening of bipolar disorder.

유한 저크(Finite Jerk)를 이용한 수직 MC(machining center)의 가속도 최적화에 대한 연구

정원지,조영덕,이춘만,윤상환 한국공작기계학회 2006 한국공작기계학회 추계학술대회논문집 Vol.2006 No.-

By the reason of increased demand of high productivity and quality, the manufacturer have an effort in many directions of a machine tool industries. Among there, we proposed method of decreasing displacement in MC(machining center). In other words, Quality related with vibration of a tool cutting products. For decreasing it, improved by optimizing a shape of the column-part and acceleration curves of motors In this paper we could find design factors has much influence on decreasing the displacement using the DOE(Design of Experiments) and optimized the level of the factors using ADAMS^(R) and MINITAB^(R). And we suggest optimized a acceleration curve using Matlab^(R).

동화합물내 동의 내각전자 결합에너지 변동과 EXAFS에 대한 연구

박종윤,이상균,이덕원 성균관대학교 기초과학연구소 1987 論文集 Vol.38 No.2

동금속과 동화합물 CuI, CuF_2 결정내의 동에 대한 K흡수스펙트럼을 수 백 eV까지 확장시켜 측정하였다. 흡수스펙트럼내 K흡수단의 변동은 각각 2.6 eV, 12.9eV였다. 이 결과는 Srivastava의 VSP 모델에 의해 잘 설명되어지나, CuF_2의 경우에는 약간의 볼일치를 가져온다. 그러나 CuF_2에 대한 것은 이미 발표된 불화합물이 가지는 이상현상과 잘 맞는다. 우리는 앞의 세 시료에 대한 EXAFS조사도 하였는데 일반적 해석방법인 Fourier 변환의 부정확성과 불편을 해소하기 위하여 위상이동의 화학적 전이성을 이용하였다. 또한 시료의 특징을 살려 최인접원자에게만 주목하던 현재의 연구방법에서 더 나아가 차인접원자에 대해서까지 적용하였다. 측정된 차인접원자간 거리는 CuI에서 4.230Å, CuF_2에서 3.270Å였다. 이는 보고된 값과 잘 일치한다. 본 실험으로 위상이동의 화학적 전위성의 간편·정확성 재확인하였다. 차인점원자에 대한 분석으로부터 EXAFS에 있어서 다중산란에의 효과를 무시할 수 있는 타당성을 제시하였다. The extended fine structure of the K-absorption spectrum of copper in copper-metal, CuI and CuF_2 have been measured. The measured edge-shifts of K-absorption edges are 2.6eV and 12.9eV. For CuI, the results is well explained by Srivastava's VSP Model. For CuF_2, the reported anomalous penomenon for fluoride compounds is also observed in the chemical edge shift. EXAFS are analyzed by using the chemical transferability of phase shift for Cu, CuI and CuF_2. In this study, we take notice of the second nearest neighbor of Cu atom of these compounds in the analysis. The distances of second nearest neighbor and 4.230Å and 3.270Å. These agree well with the values obtained from X-ray diffractions. In the case of second nearest neighbor, it is confirmed that the application of the chemical transferability of phase shift is available and that the effect of multiple scattering in analysis of EXAFS is ignorable.

온도; pH, 염분 내성 및 충격이 개불, Urechis unicinctus 유생에 미치는 영향

최상덕,김호진,라성주,정형택,윤호섭,신종암,이원교 國立 麗水大學校 環境問題硏究所 1999 環境硏究論文集 Vol.2 No.-

The effect of different temperature, salinity and pH on survival rate of Urechis unicinctus's swimming embryo was examined to develop the method for the efficient seed production. In addition to, this study was designed to investigate the possibility of pollutant marker diagnosis of marine pollutions by the change in different temperature, salinity and pH. Treatment was carried out whit different temperature (5˚C, 10˚C, 17˚C, 20˚C, 25˚C,), salinity(0‰, 10‰, 20‰, 30‰, 34‰, 40‰) and pH(4, 6, 7.2, 8.2, 9.2, 10). All the swimming embryo of the temperature experiment was survived within all experiment section, but the others experiment were not. At the temperature-shock and tolerance experiment ranging from 5˚C to 25˚C the survival rate was occurred: 75%, 95%, 100%, 100%, 50%, at the ph-Shock experiment ranging from 4 to 10, the survival rate was occurred: 0%, 50%, 85%, 100%, 60%, 0%, at the pH-tolerance experiment ranging 4 to 10 the survival rate was occurred : 0%, 75% 90%, 100%, 80%, 0%, and at the salinity-shock experiment ranging from 0% to 40% the survival rate was occurred : 0% 10% 90% 95% 100% 0% , at the salinity-tolerance experiment ranging from 0% to 40% , the survival rate was occurred : 0% 0% 90% 100% 100% 0%. These results suggest, that the survival rate of larvae of Urechis unicinctus was the highest at 17˚C, 34%. pH8.2 and this Urechis unicinctus could be live at the zone of euryceious and zone of euryhalines

위험평가(Risk Assessment)에 의한 업종별 위험(Risk)의 구분

박동욱,박덕묵,정광수,윤충식,김태형,노영만,이경남,이송권,김현욱 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.2

A total of 514 workplaces in 17 industries were inbestigated through walk-through survey. These industries were all small companies with less than five workers and didn't have work environmental measurement data. These industries were ranked by risk that was evaluated by combination of toxicity and possibility of exposure to chemical hazardous agents produced at operations of industry. Risk Index(RI) was qualitatively combined by the combination between hazard and potential of exposure to chemical hazardous agents. Industries that were regarded as having the highest risk were wood and products of wood, chemicals and chemical products, basic metals, other vehicles, trailers and semi-trailers, and fumiture manufacturing. These industries were found to have operations with higher risk than other industries. This study found that more attentions should be paid to these industries with that more attentions should be paid to these industries with high risk.

컴퓨터를 이용한 혈액학 교육시스템의 개발

이기형,손보라,윤희석,조원덕,김승택 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.1

연구목적 : 전통적인 의학교육 시스템은 최근 개발되고 있는 여러 가지 영상 진단법 등 시각적 자료를 전달하는데 한계가 있으며, 이러한 한계는 모든 분야에 걸쳐서 나타나지만 특히 혈액학이나 심장학 등 시각적인 자료가 진단에 필수적인 분양에서 두드러진다고 할 수 있다.본 연구는 혈액학 교육에 사용되던 기존의 강의실 교육에 시각적 자료가 첨부된 CD-ROM을 개발하여 혈액학 교육 시스템을 개선하기 위한 것이다. 대상 및 방법 : 기존의 혈액학 교육에 있어서 필수적으로 강의 되어오던 자료를 수집하여 체계적으로 정리하였다.강의 자료에 따라서 필요한 영상 자료를 충북대학교 병원에 입원한 혈액질환 환자들의 검사 자료로부터 수집하여 컴퓨터를 기반으로 한 의학영상 처리 및 분석시스템을 통하여 이미지 파일로 변형하였다.또한 입원 환자들 중 대표적인 증례들을 수집하여 실제 임상 진료와 유사한 형태의 증례를 통한 학습을 할 수 있도록 하였다. 결과: 본 CD-ROM은 혈액학 교육에 필요한 대부분의 영역을 포함한다 각 질환의 병태생리, 진단, 임상양상, 치료 및 예후 등 전통적으로 강의되어 오던 강의록에 이미지 파일로 변형된 영상 자료를 필요한 곳마다 링크시켰다.따라서 학습자는 특별한 장치 없이 텍스트 및 영상을 한 화면에서 볼 수 있어 전통적인 교육 시스템에 비하여 시,공간적인 장점을 갖는다 할 수 있다.또한 입원 환자들로부터 수집된 증례를 통하여 실제 임상 진료와 매우 유사한 경험을 하도록하여 교육효과를 증대시켰다. 결론: 혈액학 교육에 있어서 멀티미디어적 효과를 극대화시켜 질환의 병태생리 등 강의실 교육자료뿐 아니라 진단에 필수적인 시각적 자료를 손쉽게 접할 수 있는 CD-ROM의 개발로 전통적인 강의방법이 갖는 한계를 개선시킬 수 있을 것으로 기대된다. Purpose : The traditional medical education system has its limitations in effectiveness of conveying informations in multiple modalities used in diagnosis of patients with hematologic diseases.This study was performed to develop such a multimedia system using computer based CD-ROM, which includes visual assistant systems, several hematological case studies as well as the traditional text-wise education systems. Materials and Methods: The informations about hematologic diseases were compiled and organized.The main visual data was peripheral blood smears, bone marrow data, and several laboratory results accrued from patients admitted to Chungbuk National University Hospital.Each visual data were transformed through computer-based medical image processing and analyzing system and saved as to JPEG files.Case studies were also acquired from admitted patients and the laboratory data of that patients were used unmodified as possible as. Results : The CD-ROM covers almost all kinds of hematologic diseases that must be included in ordinary medical education courses.The text part includes pathophysiology, diagnosis, clinical features, treatment and prognosis of each hematologic diseases.The essential visual data were linked to each text part and accessible with ease, by one click.Case studies were simulated to actual clinical settings and presented step by step from diagnoses to treatments. Conclusion: A multimedia approach for the study of hematologic diseases has been developed and available in CO-ROM format.This system has advantage over traditional education system in conveying all kinds of visual data which is essential in educating hematologic disorders.

의료관계 해부 감정예의 분석적 연구(I) : 1990년 국립과학수사연구소 감정예

姜信夢,李垣兌,李漢榮,尹順雄,全基悳,金相鉉,徐在冠,尹重鎭 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

A study of 118 autopsy cases associated with medical care in 1990 was present according to the medical department, the mode of treatment and the cause of death. The Pediatrics showed the highest rate (25.4%), followed by the Obstetrics & Gynecology (22.9%), and Internal medicine (20.2%). According to the mode of treatment, medical accidents during operation and anesthesia were 29 cases (24.6%) with highest rate in Obstetrics & Gynecology (13 cases), 38 cases (32.2%) were during medication and/or injection with highest rate in Internal Medicine (18 cases), and 51 cases (43.2%) were during general medical practice with highest rate in pediatrics (19 cases). The most prevalent cause of death was the disease of respiratory system (34.9%, 30 cases) and the diseases of cardiovascular and urogenital system accounted for 31.4% and 11.6% respectively. The main cause of death in Internal medicine was the disease of cardiovascular system (11/24 cases), the respiratory system in pediatrics (15/30 cases) and the disease of urogenital system in Obstetrics & Gynecology (9/27 cases. ) Asphyxial deaths were 7 cases and the death due to adverse drug reaction accounted for 10 cases.

감성돔, Acanthopagrus schlegeli의 종묘생산 및 성분화에 미치는 영향

한종석,김용구,라성주,윤호섭,이원교,김정,최상덕 國立 麗水大學校 環境問題硏究所 2002 環境硏究論文集 Vol.5 No.-

This study was carried out to produce the seeding of the larvae and juvenile of black sea bream, Acanthopagrus schlegeli in terms of artificial hatching, feeding behavior and growth rate in each factor. Total length of black sea bream larvae hatched was 2.57±0.35mm and after 50 days, total length was 22.08±3.74mm, 49.7% in survival rate. This research was conduced to confirm the effect of tributyltin and 2,4-dinitrophenol on the sex differentiation in Black Sea bream, Acanthopagrus schlegeli. Fish were reared of oral administration of tributyltin at 0.05, 0.5, 5㎍/g and 2,4-dinitrophenol at nominak concentration of 0.05, 0.5, 5, 50㎍/g diet from 156 days to 185 days after hatching. In the process of the differentiation until 156 days after hatching, gonads were composed testis. In contrast, 185 days after hatching, testis were composed of a number of spermatogonia and sperm duct. The female in the control in which sex differentiation of Acanthopagrus schlegeil was normally conducted was 100%. The experimental unit of estradiol-17β, it was 100% in 0.05㎍/g diet concentration, which was similar to the sex ratio of the control. And it was 100% in 0.5㎍/g diet concentration. In each experimental unit with 5, 50㎍/g diet concentrations, every individuals of them differentiated to males. About the experimental unit of tributyltin, the females were 100%, 100%, 100%, 100% and 100% in 0.05㎍/g, 0.5,㎍/g, 5㎍/g and 50㎍/g diet concentrations, respectively. About the experimental unit of 2,4-dinitrophenol, the males were 100% tn 0.05, 0.5, 5, 50㎍/g diet concentrations, respectively.