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      • KCI등재

        Effect of Total Hip Arthroplasty on Ipsilateral Lower Limb Alignment and Knee Joint Space Width: Minimum 5-Year Follow-up

        Choi Yun Seong,Park Jung-Wee,Kim Tae Woo,Kang Kee Soo,Lee Young-Kyun,Koo Kyung-Hoi,Chang Chong Bum 대한의학회 2023 Journal of Korean medical science Vol.38 No.20

        Background: This study aimed to 1) assess the effect of total hip arthroplasty (THA) on coronal limb alignment, namely, the hip–knee–ankle angle (HKA), 2) identify factors that determine changes in the HKA, and 3) determine whether alignment changes influence the knee joint space width. Methods: We retrospectively evaluated 266 limbs of patients who underwent THA. Three types of prostheses with neck shaft angles (NSAs) of 132°, 135°, and 138° were used. Several radiographic parameters were measured in the preoperative and final radiographs (at least 5 years after THA). A paired t-test was used to confirm the effect of THA on HKA change. Multiple regression analysis was performed to identify radiographic parameters related to HKA changes following THA and changes in knee joint space width. Subgroup analyses were performed to reveal the effect of NSA change on the HKA change, and the proportion of total knee arthroplasty usage and changes in radiographic parameters between maintained joint space and narrowed joint space groups were compared. Results: The preoperative mean HKA was 1.4° varus and increased to 2.7° varus after THA. This change was related to changes in the NSA, lateral distal femoral angle, and femoral bowing angle. In particular, in the group with a decrease in NSA of > 5°, the preoperative mean HKA was largely changed from 1.4° varus to 4.6° varus after THA. The prostheses with NSA of 132° and 135° also led to greater varus HKA changes than those with an NSA of 138°. Narrowing of the medial knee joint space was related to changes in the varus direction of the HKA, decrease in NSA, increase in femoral offset. Conclusion: A large reduction in NSA can lead to considerable varus limb alignment after THA, which can have adverse effects on the medial compartment of the ipsilateral knee.

      • Factors associated with inflammatory change of epidermal cyst

        ( Jisang Yun ),( Kyung-nam Bae ),( Jin-hwa Son ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byungsoo Kim ),( Moon-bum Kim ),( Kihyuk Shin ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1

        Background: Epidermal cysts (EC) are the most common tumors found on the skin and accompanying inflammation is also frequent. However, the predictors for inflammatory change have not been investigated yet. Objectives: This study was performed to investigate the difference between inflamed and uninflamed epidermal cysts, and to assess associated factors for inflammatory change. Methods: We analyzed the biopsy-proven 1723 epidermal cysts (515 inflamed and 1208 uninflamed) at two tertiary hospitals from 2011 to 2021. Results: The proportion of inflamed epidermal cysts (IEC) and uninflamed epidermal cyst (UIEC) were 29.9 % and 70.1 %, respectively. Inflammatory change was less frequently observed on the face (25.5 %) than the other sites (32.1 %) (p=0.0046). The anatomic location with the highest rate of inflammatory change was back (40.8 %, p=0.0004). Mean duration of inflammatory change from UIEC to IEC on the face was shorter than the other sites (12.5 months vs 17.9 months, respectively, p= 0.0473). On ultrasonography, long axis of IEC (20.7mm) was generally longer than that of UIEC (15.7mm) (p=0.0218). Moreover, Inflammatory change was more frequent on the EC with punctum compared to those without punctum (35.3 % vs 30.3 %, P=0.0471). Conclusion: Based on the location, size and presence of punctum, decision on the optimal treatment strategies can be established when encountering patients with EC.

      • FC 2-8 : Factors associated with inflammatory change of epidermal cyst

        ( Jisang Yun ),( Kyung-nam Bae ),( Jin-hwa Son ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byungsoo Kim ),( Moon-bum Kim ),( Kihyuk Shin ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.-

        Background: Epidermal cysts (EC) are the most common tumors found on the skin and accompanying inflammation is also frequent. However, the predictors for inflammatory change have not been investigated yet. Objectives: This study was performed to investigate the difference between inflamed and uninflamed epidermal cysts, and to assess associated factors for inflammatory change. Methods: We analyzed the biopsy-proven 1723 epidermal cysts (515 inflamed and 1208 uninflamed) at two tertiary hospitals from 2011 to 2021. Results: The proportion of inflamed epidermal cysts (IEC) and uninflamed epidermal cyst (UIEC) were 29.9 % and 70.1 %, respectively. Inflammatory change was less frequently observed on the face (25.5 %) than the other sites (32.1 %) (p=0.0046). The anatomic location with the highest rate of inflammatory change was back (40.8 %, p=0.0004). Mean duration of inflammatory change from UIEC to IEC on the face was shorter than the other sites (12.5 months vs 17.9 months, respectively, p= 0.0473). On ultrasonography, long axis of IEC (20.7mm) was generally longer than that of UIEC (15.7mm) (p=0.0218). Moreover, Inflammatory change was more frequent on the EC with punctum compared to those without punctum (35.3 % vs 30.3 %, P=0.0471). Conclusion: Based on the location, size and presence of punctum, decision on the optimal treatment strategies can be established when encountering patients with EC.

      • KCI등재후보

        약물 중독 시 위 세척에 의한 산 - 염기 평형 및 전해질의 변화

        윤형란(Hyung Ran Yun),손동현(Dong Hyun Sohn),이창범(Chang Bum Lee),이재웅(Jae Woong Lee),양석철(Suck Chul Yang),한동수(Dong Soo Han),손주현(Ju Hyun Sohn),김순길(Soon Kil Kim),김호중(Ho Jung Kim) 대한내과학회 1998 대한내과학회지 Vol.54 No.4

        N/A Objectives: There is little information on the imbalance of electrolyte and acid-base metabolism associated with gastric lavage in acute drug intoxication patients. This study was aimed to analyze the acid-base and electrolyte abnormalities associated with gastric lavage in acute drug intoxication patients. Methods: We studied 24 acute drug intoxication patients who had performed gastric lavage with 10 liters of 0.9% NaC1. Electrolyte parameters and arterial blood gas analysis were carried out before and after gastric lavage. Results: After gastric lavage, acidosis was reduced in general. But there was no significant change in pH (7.34±0.02 vs. 7.38±0.15, p=NS). In acid-base balance, the mixed form of metabolic acidosis and respiratory acidosis was reduced from 7 to 2 cases, and the simple form of respiratory acidosis was reduced from 3 to 1 case. In contrast, normal form was increased from 5 to 7 cases and the simple form of metabolic acidosis was increased from 2 to 6 cases. In electrolyte parameters, serum sodium was reduced significantly (145±1.0 mEq/L vs. 141±0.8 mEq/L, p<0.01), but there was no case of significant hyponatremia (<135mEq/L). Bicarbonate level (20±1.1 mEq/L vs. 22±0.9 mEq/L, p< 0.05) and anion gap (19±1.6 mB vs. 13±1.3 mEq/L, p< 0.01) showed significant change. But, blood levels of potassium (3.6±0.1 mEq/L vs. 3.8±0.1 mEq/L, p=NS), chloride (106±0.6 mEq/L vs. 106±0.6 mEq/L, p=NS) and F'aCO2 (36±1.mmHg vs. 37±1.5 mmHg, p=NS) were no significant change before and after gastric lavage. Conclusions: Gastric lavage with 10 liters of 0.9% NaC1 in acute drug intoxication patients did not show clinically significant changes in electrolytes and acid-base balance.

      • KCI등재후보

        콤바인 HST 전자제어시스템 개발

        서신원(Sin-Won Seo),허윤근(Yun-Kun Huh),이제용(Je-Yong Lee),이창규(Chang-Kyu Lee),배근수(Keun-Soo Bae) 충남대학교 농업과학연구소 2011 농업과학연구 Vol.38 No.1

        I/An electro-hydraulic transmission having advantages of convenience, safety, simple linking and high power, and an electronic control system were designed and fabricated. In this study, characteristics of the control system were investigated through outdoor tests for evaluation of installation of the system on a combine. Major findings were as followings. 1. Experiment for performance evaluation of the control system was conducted on concrete road. With steering lever in neutral position, driving HST swash plate and left/right wheel speed increased in proportion to driving lever angle. In case of steering control, steering swash plate angle changed in proportion to steering lever angle. This should cause increase in outer wheel speed, but it was observed that HST swash plate was controlled toward neutral to maintain the speed before steering. As a result, speed before steering was maintained despite the change in outer wheel speed by steering HST swash plate angle change. 2. It was observed that the HST system enabled steering with outer wheel maintained at constant speeds while inner wheel speed decreased, which was more stable than conventional mechanical links. In addition, for the selected 5 criteria, experiment showed satisfactory results and it was judged that installation on real vehicle would be feasible. 3. The control system showed response property of appropriate forward/reverse movement and lift/right steering, without causing any problems during experiment on concrete. Result of response property experiment on field operation also showed appropriate control over forward/reverse movement and left/right steering

      • SCISCIESCOPUS

        Interferon-γ Inhibits in vitro Mobilization of Eosinophils by Interleukin-5

        Park, Choon-Sik,Choi, Eun Nam,Kim, Jung Sun,Choi, Yun Sung,Rhim, Tai Youn,Chang, Hun Soo,Chung, Il Yup S. Karger AG 2005 International archives of allergy and immunology Vol.136 No.3

        <P><I>Background:</I> Th2 cytokines play pivotal roles in allergic inflammation, including eosinophilia, and their actions are antagonized by Th1 cytokines, conferring them therapeutic potential. <I>Methods:</I> In this study, we examined the ability of a number of cytokines to suppress the activation of eosinophils that function as effector cells for allergic airway diseases. <I>Results:</I> Interleukin (IL)-5, IL-6, and tumor necrosis factor (TNF) induced an eosinophil shape change, whereas interferon (IFN)-γ significantly inhibited the shape change. Other cytokines, including IL-1β, IL-4, IL-10 and IL-13, had little or only slightly enhancing or reducing effects on the shape change. We further analyzed the IFN-γ effect, showing that pretreatment with IFN-γ strongly suppressed IL-5-induced eosinophil shape change, and cycloheximide (CHX) abrogated the suppression by IFN-γ, suggesting that new protein synthesis is required for the inhibitory effect by this cytokine. In agreement with these results, IFN-γ blocked the eosinophil migration and ERK phophorylation induced by IL-5, and the addition of CHX restored eosinophil chemotaxis. <I>Conclusions:</I> Collectively, IFN-γ may attenuate eosinophilic inflammation by directly negating eosinophil mobilization.</P><P>Copyright © 2005 S. Karger AG, Basel</P>

      • KCI등재

        40ㆍ50대 일부 남성근로자의 골감소증 및 골다공증 유병실태와 위험요인

        장윤균,서현주,진영우,정미선,성숙희,박두용,김종순,김수근 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

        목적: 최근 국내에서도 골다공증과 관련된 생활양식의 규명에 관한 연구가 이루어지고 있으나, 아직까지 남성 골다공증에 대한 연구가 활발하게 이루어지지 않아 40, 50대 남성근로자를 대상으로 유병률을 파악하고, 골감소증 및 골다공증 관련 위험요인을 확인하고자 하였다. 방법: 원자력발전소에 근무하는 40, 50대 남성 근로자 2,073명을 대상으로 2004년 3월~7월 기간동안 생활습관을 파악하기 위하여 자기기입식 전산입력 방식으로 최종학력, 흡연여부, 음주여부, 신체활동 횟수를 조사하였고, 골밀도검사, 체성분검사(체지방률, 허리-엉덩이둘레비), 신체계측(신장, 체중)을 시행하였고, 골밀도 검사는 Osteosys사의 EXE-3000을 이용하여 종골부위를 측정하였고, 체지방률, 허리-엉덩이 둘레비는 Biospace사의 Inbody 3.0을 이용하여 측정하였다. 통계분석은 골감소증 및 골다공증의 관련요인을 분석하기 위해 다중로지스틱회귀분석을 시행하였다. 결과: 연구대상자의 골감소증 및 골다공증 유병률은 22.8%와 3.0%이었으며, 골감소증 및 골다공증의 관련요인으로는 연령이 증가할수록, 흡연자이거나 과거흡연자일 경우, 체질량지수가 25 kg/m^(2) 미만일 경우, 30분 이상 신체활동 횟수가 주 3회 미만일 경우가 유의한 연관성이 있었다. 결론: 성인 남성 40, 50대의 골감소증 및 골다공증의 유병률이 높은 편이었으며, 골감소증 및 골다공증으로 이환을 예방하기 위하여 금연, 활발한 신체활동을 촉진하여 골밀도를 개선시키는 생활습관으로의 변화를 권고해야 할 것이다. Objective: This study was conducted to investigate the prevalence and risk factors of osteopenia and osteoporosis in 40-59 year-old male workers working at nuclear power plants. Methods: Bone density, body composition, and anthropometry data were analyzed for 2,073 subjects were carried out from March 2004 to July, 2004. Educational level, smoking status, drinking status and frequency of physical activity were investigated by self-reported questionnaires through internet to identify lifestyles related to bone mass density. Bone mass density was measured by EXE-3000 of Osteosys Co. And body fat percentage, and waist-to-hip ratio by inbody 3.0 of Biospace Co. Results: The prevalence of ostepeniaosteopenia and osteoporosis was 22.8% and 3.0%, respectively. According to multinominal multinomial logistic regression analysis, age, smoking status (current smoker and former smoker), low body mass index (< 25kg/m^(2)), and frequency of physical activity were significantly associated with osteopenia and osteoporosis. Conclusions: The prevalence of ostcopenia and osteoporosis wasseemed high for the, when it was inferred from subjects' age compared to the results of previous studies. The This study results suggeststhat it is necessary for 40-59 year-old male workers to stop smoking, and exercise regularly in order to prevent osteopenia and osteoporosis.

      • 와이브로(WiBro) Model frame mapper Hardware 구조 설계

        윤창중,임웅철,김진상,조원경,김영수,서덕영 경희-다반 ASIC 설계교육센터 2005 경희-다반 ASIC센터 논문집 Vol.6 No.-

        WiBro는 하향 링크와 상향 링크를 시간으로 구분하는 TDD방식이 사용되며 다중접속 방식으로는 OFDMA가 사용된다. WiBro 서비스의 특징들은 frame Mapping 과정에서 잘 나타난다 frame은 하나의 frame당 42개의 symbol 단위로 mapping 되며 TFFT Block에서는 하나의 symbol 단위로 frame mapper에서 Data를 불러와 처리한 후 CP insertion, windowing 과정을 거쳐서 단말에 전송한다. 본 논문에서는 WiBro 서비스를 위하여 TTA에서 제정한 표준안을 토대로 모뎀부분을 VHDL 언어를 이용하여 하드웨어로 설계 하였고 Xilinx Vertex 8000을 Target Device로 이용하였다.

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