신장의 사춘기 성장 동안 초경 발생 시기와 성장 곡선의 형태에 관한 연구

안용수,이기수,남종현,강윤구 대한치과교정학회 2009 대한치과교정학회지 Vol.39 No.3

이 연구는 만 7세부터 17세까지의 신장의 누년적 변화를 통해서 사춘기 최대 성장기와 초경 발생 시기와의 관계를 평가하고, 성장 곡선의 형태에 따라 성장 곡선을 분류하여 각 형태별 특징을 파악하고자 시행하였다. 경기도 화성에 있는 삼괴 고등학교에서 1학년부터 3학년까지 96명의 생활기록부에 기재되어 있는 신장의 누년적인 자료가 이용되었으며, 초경 시기와 전신적 질환 유무는 설문지를 통해 조사되었다. 사춘기 성장 가속기는 9.9세에 시작하여 11.6세에 최대 성장기를 이루고 14.1세경에 끝났다. 초경은 12.6세에 일어나며 76.1%는 최대 성장기 이후에 나타나고 최대 성장기와는 1년의 차이를 보인다. 10.4%에서 최대 성장기 전에 초경이 나타났고 13.5%에서는 최대 성장기와 동일한 시점에 나타났다. 초경 시기와 관계없이 사춘기 성장 가속 기간은 4.2년으로 일정하게 나타난다. 성장 곡선을 4가지 형태로 분류하였으며, A형은 51.1%, B형은 21.9%, C형은 20.8%, D형은 6.2%의 분포를 보인다. C형의 성장 가속 기간이 가장 길게 나타난다. B형과 C형에서 PHV가 두 개인 경우는 B형과 C형의 58.5%인 24명에서 나타났다. 이상의 연구 결과에서 개개인의 성장 양상은 개인차가 크며 초경뿐만 아니라 누년적인 성장을 참고로 하여 onset의 정확한 시기와 성장 곡선 형태를 파악할 수 있다면 남은 성장 기간 예측에 도움을 줄 것으로 생각된다. Objective: This study investigated the onset, peak height velocity (PHV) and end of adolescent growth spurt as well as menarcheal timing deduced from surveying accumulative height growth over many years. Methods: Ninety six students of Samgoe high school between 1st and 3rd grade that were in good health participated in the research. A survey questionnaire was distributed to examine the students’ health status and menarche timing. Results: Adolescent growth spurt typically began at the age of 9.9 and reached a PHV at the age of 11.6. The growth spurt ended at the age of 14.1 on average. The average age of menarche was 12.6 years, which was about one year after the PHV of adolescent growth spurt. In most cases, menarche came after PHV. But in 24% of the students, menarche and PHV was nearly coincident or menarche preceded PHV. The growth curves were classified into four types. A typical adolescent growth spurt showed one PHV on graph that drastically drops after the PHV. However, there were cases with two PHVs. Conclusions: The results indicate that individual growth patterns show large individual differences, however the categorization into the various growth curves may aid in predicting individual growth patterns.

계열별 고등학생집단의 뇌기능특성화 경향에 대한 연구

윤규태,최기수,안의태,고정식,양남길,박경호 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

본 연구에서는 계열에 따른 고등학생들의 대뇌반구기능의 특성화 또는 편재화의 경향을 알아보고, 전공분야에 대한 적응력과의 상관관계를 검토하고자 했다. 일반고등학교 인문계열 학생 359명, 자연계열 학생 371명, 음악과 미술전공 학생을 포함한 예능계열 196명, 체육특기자를 포함한 체육계열 학생 151명 등 1,077명을 대상으로 각 계열별, 남녀별, 성적별 고등학생 집단들의 대뇌반구의 특성화, 편재화 경향을 시나가와(품川)질문지법을 이용하여 분석하였으며, 다음과 같은 결과를 얻었다. 1. 인문계열 고등학생의 뇌기능의 편재화 경향은 우뇌형 54.3%, 양쪽뇌형 32.6% 및 좌뇌형 13.1%였다. 남녀별로는 남학생은 우뇌형 62.9% 양쪽뇌형 27.9% 및 좌뇌형 9.5%로 나타났으며, 여학생은 각각 43.7%, 38.6% 및 17.7%로서 여학생이 남학생에 비하여 죄뇌화 경향을 보였다. 2. 자연계열 고등학생의 경우는 우뇌형 56.9%, 양쪽뇌형 29.9% 및 좌뇌형 13.2%로서 인문계열 고등학생과 비슷한 분포를 보였다 이를 남녀별로 구별하여 보면 남학생은 62.2%, 27.1% 및 10.2%, 여학생은 51.5%, 32.5%및 16.0%의 분포를 보여, 역시 여학생의 좌뇌화 경향이 뚜렷했다. 3. 예능계열 고등학생의 경우는 우뇌형 56.1%, 양쪽뇌형 35.2% 및 좌뇌형 8.7%의 분포를 보였으며, 이를 전공별로 세분해서 살펴보면 음악전공학생의 경우 53.7%, 35.5% 및 10.7%로서 전체 평균과 거의 비슷한 분포를 보였으나, 미술전공학생의 경우 60.0%, 34.7% 및 5.3%로서 , 특히 좌뇌형의 경우 음악전공에 비해 절반수준에도 못 미치는 경향을 보였다. 4. 체능계열 고등학생 집단의 경우 우뇌형 50.3%, 양쪽뇌형 37.7% 및 좌뇌형 11.9% 분포를 보였다. 5. 성적별로 보면 일반고등학교 학생 가운데 성적 우수 집단은 뚜렷하게 좌뇌형 경향(25.6% 및 25.0%)을 보였다. 6. 예능계열의 우수집단은 양쪽뇌형의 분포비율(50.0% 및 44.4%)이 특히 높았다. 7. 체육계열의 우수집단은 좌뇌형 분포(21.6%)가 높았다. According to the advanced study on differential theory of brain function, the left hemispheric functions are concerned more on the verbal, logical, sequential and arithmetic abilities, whereas the right hemisphere has characteristics of non-lingual, general, creative and aesthetic abilities. The authors compared the tendency of hemispheric specialization in high school students with different educational condition and facilities. Sinakawa's questionnaire method was the instrument for this study. The results obtained were as follows: Among 1,077 of whole subjects, right hemispheric dominant type was 55.0% (59.1% in male, 51.0% in female), bilateral type was 32.9% (10.6% in male, 35.1% in female) and left hemispheric dominant type was 12.2% (10.4% in male, 13.9% in female). 1. Of the 359 subjects in the field of humanity science, right hemispheric dominant type was 54.3% (62.9% in male, 43.7% in female), bilateral type was 32.6% (27.9% in male, 38.6% in female) and left hemispheric dominant type was 13.1% (9.5% in male, 17.7% in female). 2. Of the 371 subjects in the field of natural science, right hemispheric dominant type was 56.9% (62.2% in male, 51.5% in female), bilateral type was 29.9% (27.1% in male, 32.5% in female) and left hemispheric dominant type was 13.2% (10.2% in male, 16.0% in female). 3. Of the 196 art school students, 56.1% was regraded as right hemispheric dominant type, students majoring music was 53.7%, 35.5% and 10.7%, respectively, whereas the frequency for students majoring find art was 60.0%, 34.7% and 5.3%. 4. In students majoring physical education, 50.3% were shown in right hemispheric dominant type, 37.7% were bilateral type and 11.9% were left hemispheric dominant type. 5. Laterality patterns of students who adapt more successfully to their specific studying fields show following characteristics; Successful students of general high school show pronounced left shift in their laterality pattern, whereas successful students of art school exhibit more bilateral type. And successful students of physical education school show left shift in their laterality patterns.

엘라스타제의 토끼에 대한 최기형시험

안병옥,백남기,이순복,김원배,양중익,이영순,임윤규 A.R. Liss 1990 ENVIRONMENTAL MUTAGENS AND CARCINOGENS Vol.10 No.2

천연 제올라이트를 이용한 고농도의 칼슘이온 제거 : 이온교환속도 및 이온교환능 Kinetics and Isotherm

안봉규,오재일,윤석민,임남웅 대한상하수도학회 2003 상하수도학회지 Vol.17 No.1

The concentrated calcium removal from industrial wastewater by natural zeolite was examined to reduce inhibitory effects of those ions on the biological treatment in down-stream. It is well known that natural zeolite possesses good cation exchange capacity. Kinetic studies by using a batch-type methods demonstrated that the adopted particle size(1-2, 2-2.8, 2.8-4㎜) of zeolites showed similar exchange trends of calcium ions and showed relatively fast exchange reaction within 1 hour in spite of various zeolite dosages. The influence of the temperature on the ion-exchange capacity (isotherm) was examined. It was found that calcium exchange capacity(4.464㎎-Ca^2+/g-zeolite) at low temperature of 5℃ was double up to 9.225㎎-Ca^2+/g-zeolite at the range of 22-40℃. However, ion exchange efficiencies were similar at each condition of pH 6,7,8,10.

직업적인 납 노출이 없는 일부 중년 한국인의 골중납량 및 혈중납량

김남수,최성우,김진호,함정오,박해윤,안규동,이병국 大韓産業醫學會 2007 대한직업환경의학회지 Vol.19 No.4

목적: 우리나라에서 납에 직업적으로 노출되지 않은 일부 중년 성인들의 골중납량과 혈중납량의 수준과 상호관련성을 알아보기 위하여 40세 이상 남자 86명 여자 51명 총 137명을 대상으로 본 연구를 시도하였다. 방법: 연구변수로 골중납량인 경골납량,혈중납량을 택하였다. 경골납량은 K-shell XRF를 이용하여 각 대상 자들을 30분간 측정하였고,혈중납량은 원자흡광광도계법으로 분석하였다. 결과: 총대상자 137명의 경골납량의 평균±표준편차는 3.49±4.99 μg/g이었으며, 남자와 여자는 각각 3.90± 4.88 μg/g 및 2.80±5.14 μg/g이었으나 양군 평균의 통계적 차이는 없었다. 한편 총대상자 137명의 혈중납량의 평균±표준편차는 3.70±1.35 μg/dl이었으며,남자와 여자는 각각 3.93±1.25 μg/dl 및 3.30±1.42 μg/dl이었으나 양군 평균의 통계적 차이는 없었다. 음주,흡연 및 BMI를 통제한 후 혈중납량을 종속변수로 한 중 회귀분석에서 연령은 양의 영향을 주는 변수로 나타났다. 여자대상자만을 대상으로 한 중 회귀분석에서 교란변수를 통제한 후 연령은 경골납량에 경계수준의 양의영향을 나타내었다. 결론: 40세 이상의 우리나라 중년성인의 경골납량의 평균±표준편차는 3.49±4.99 μg/g이었으며,혈중납량의 평균±표준편차는 3.70±1.35 μg/dl이었다 혈중납량은 연령과 성과 유의한 양의 관련성이 있었으나,골중납량은 여자에서만 연령과 경계수준의 유의한 관련을 나타냈다. Objectives: In order to investigate the level and the association between bone lead and blood lead levels of non-occupationally, lead-exposed Koreans, the authors studied the lead biomarkers of 137 middle aged Koreans (86 males and 51 females) older than whose age were above 40 years. Methods: The tibia lead level was selected as the bone lead indicator of cortical bone, and the blood lead level was also measured. The tibia lead level was measured by K-shell XRF with 30-minute measurement of each subjects. The blood lead level was analyzed by AAS method. Results: The mean (SD) of the tibia lead level of the 137 study subjects was 3.49 (4.99) ,㎍/g, and tended to be higher. The mean (SD) of tibia lead level in male subjects (was 3.90 (4.88) ㎍/g) and larger than in that of female subjects (2.80 (5.14) ㎍/g), but without no statistical significance was observed. The mean (SD) of blood lead level of all total subjects was 3.70 (1.35) ,㎍/dl, and tended to be higher. The mean (SD) of blood lead level in male subjects (was 3.93 (1.25) ㎍/dl) and larger than in that of female subjects (3.30 (1.42) ㎍/dl), but without no statistical significance was observed. In multiple regression analysis of blood lead levels after adjusting for covariates, age was a significant independent variable. A weak association of age with tibia lead in female subjects was also observed in multiple regression analysis. Conclusion: The mean (SD) of tibia and blood lead levels of middle aged Koreans whose ages were over 40 years old were 3.49 (4.99) ㎍/g and 3.70 (1.35) ㎍/dl, respectively. Age and sex were positive predictors of blood lead level in multiple regression analysis after controlling for the covariates. However, in multiple regression analysis whereas age was weakly association with tibia lead level only in female subjects in multiple regression analysis.

흰쥐 뇌에서 Tyrosine Hydroxylase분비세포의 출현시기 및 분포에 관한 면역조직화학적 연구

정윤영,선희매,김영택,김남훈,안계훈,장인엽,김종중,문정석,강양수 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

The immunohistochemical (ABC method) studies on the ontogeny and localization of the catecholamine-synthesizing enzyme tyrosine hydroxylase (TH) were examined in rat brain from the 12th fetal day until the 9th postnatal day. The results obtained were as follows : 1. Tyrosine hydroxylase was first detected immunohistochemically at embryonic day 13(E13). At this stage, the TH-containing neurons were still migrating and cytologically immature. 2. The changes occuring from the early to the late prenatal stages of development appeared to be the result of an increase in the number and size of the TH-containing cells and in the length of nerve fibers. 3. The distribution of the TH-containing neurons at embryonic day 19(E19) more closely resembled catecholaminergic neurons in the adult rat brain : 1) a rhombencephalic group became the A1-7 ; 2) a ventral mesencephalic group became A8-10 ; 3) a ventral prosencephalic group and a few neurons ventral to the striatum became A11-14 ; and 4) the cells of the olfactory bulb corresponded to the A15. 4. The cytodifferentiation of the TH-immunoreactive neurons was accompanied by continued migration to form the collective catecholaminergic groups during ontogenesis. In addition, the morphology of the TH-immunoreactive neurons in the late prenatal stage resembled in the adult rat brain.

청소년 식이태도와 식이행동의 횡문화적 연구

백영석,안동현,조연규,남정현,최보율,강윤주,고복자 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.3

연구목적 : 청소년을 대상으로 장애가 있는 식이태도 및 식이행동과 관련된 요인들에서 인종과 문화적 차이가 있는가를 보는 것이다. 방 법 : 1996년도에 3129명의 중고등학교 남녀 학생을 대상으로 학교 장면에서 신체 계측과 설문지를 통하여 수집하였으며 연령은 13세부터 16세 사이의 학생들로 분포되었다. 학생들의 분포는 서울 지역의 663명, 양평 지역의 821명, 조선족이 사는 연길 지역의 830명 그리고 한족이 사는 길림 지역의 815명이었으며, 그들은 모두 키, 몸무게, 신체질량지수, 부모의 수입, 아버지의 학력, 체중조절 설문지, 신체상 척도 및 식이태도검사 등의 내용을 완성하였다. 결 과 : 신체질량지수(BMI)에서는 지역, 성별, 사회경제적 상태에 따른 차이가 없었다. 연길과 길림 지역의 학생들이 서울과 양평 지역의 학생들보다 심한 저체중과 심한 과체중을 갖는 학생들이 많았다. 연길과 길림 지역의 학생들이 서울과 양평의 학생들보다 식이태도검사(EAT-26)의 평균치가 높아 식이태도와 식이행동이 나빴다. EAT-26의 20점 이상인 식이장애의 고위험군은 연길 지역의 학생이 6.9%로 네 집단 중에서 가장 많았다. 한국의 양평지역과 서울 지역의 학생들이 신체상 척도(BIS)의 평균치가 연길 지역과 길림 지역의 학생들보다 의미있게 높았다. 즉 한국의 학생들이 중국의 학생들보다 자신의 신체에 대하여 부정적인 생각을 갖고 있었다. 체중조절 행동의 유병율은 서울 지역 학생들이 26.7%, 양평 지역 학생들이 23.2%, 연길 지역 학생들이 10.6%, 그리고 길림 지역 학생들이 4.6%이었다. 식이조절과 운동은 한국의 학생들이, 식이조절과 약물사용은 중국의 학생들이 가장 많이 하는 방법이었다. 결 론 : 본 연구를 통하여 한국과 중국에서도 식이장애가 결코 적지 않을 것이라는 사실을 확인하였고, 식이장애는 인종과 사회문화적 요인에 의해 크게 영향을 받는다는 것, 마지막으로 식이태도와 식이행동 및 그와 관련된 요인들을 통해서 네 지역간의 문화전이 상태를 확인할 수 있었다. Objectives : The goal of this research was to attempt to examine ethnic and cultural differences in factors associated with disordered eating attitudes and behaviors. Methods : Data were collected from the four groups of 3,129 high school students aged between 13 and 16 years who completed school-based survey conducted in 1996. The students (663 Korean urban, 821 Korean rural, 830 Korean-Chinese and 815 Chinese adolescents) completed an instrument which assessed weight, height, Body Mass Index(BMI), parental income, father's level of education, weight control questionnaire, Body Image Scale(BIS), and eating attitudes and behaviors using the Eating Attitude Test-26(EAT-26). Results : BMI did not vary significantly by race, sex, and socioeconomic status. There were many severely underweight and severely overweight students among Korean-Chinese and Chinese than among Korean urban and Koran rural students. The EAT-26 mean scores of Korean-Chinese and Chinese subjects were significantly higher than those of Korean urban and Korean rural subjects. The EAT-26 mean score of Korean-Chinese was the highest among the four racial groups. The prevalence of high risk EAT-26(EAT-26≥20) students of Korean-Chinese was 6.9% which was the highest among the four groups. The BIS mean scores of Korean rural and Korean urban subjects were significantly higher than those of Korean-Chinese and Chinese subjects. The Korean subjects were more dissatisfied with their body than the Chinese. The prevalences of weight control behaviors were 26.7% in Korean urban, 23.2% in Korean rural, 10.6% in Korean-Chinese, and 4.6% in Chinese subjects. Dieting and exercise were most popular for weight reducing in Korean subjects. Dieting and drug use were most popular in Chinese subjects. Conclusion : These data suggest that there must be many eating disorder patients in Korea and China, and the eating attitudes and behaviors are influenced by ethnic and cultural factors. Implications for understanding sociocultural influence on eating attitudes and behaviors and acculturation are discussed.

대학생집단의 뇌기능 특성화 경향에 대한 연구

최기수,윤규태,안의태,양남길,고정식,박경호 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

체육학과 학생 163명과 국가대표선수 211명을 포함한 체육 전공자들과 의과대학생 282명, 문과대학생 101명, 신학전공학생 96명 그리고 간호학과 전공학생 100명, 계 953명을 대상으로 남녀 대학생들의 대뇌반구의 특성화, 편재화 경향을 시나가와 ( 品川)질문지 법을 이용하여 분석한 결과 다음과 같은 결과를 얻었다. 1. 체육과 남학생은 우뇌형 45.6%, 좌우뇌형 47.4%, 좌뇌형 7%로 나타났으며, 여학생의 경우 우뇌형 41.6%, 좌우뇌형 44.3%, 좌뇌형 14.2%로 나타났다. 2. 대표선수의 경우 우뇌형과 좌우뇌형에서 일반 체육학과 학생과 유사한 분포를 보였으나, 좌뇌형이 남자 12.9% 여자 12.6%로 남녀 고른 분포를 나타냈다. 3. 의과대학생의 경우 남학생은 우뇌형 63.5% 좌우뇌형 24.9% , 좌뇌형 11.6%인 반면, 여학생은 우뇌형 50%, 좌우뇌형 22.9%, 좌뇌형 27.1%로 나타났다.. 4. 문학은 전공하는 남녀학생과 신학을 전공하는 학생은 우뇌형, 좌우뇌형, 좌뇌형의 순으로 유사하게 나타났다. 5. 간호학전공 학생의 분포는 우뇌형42.0% 좌우뇌형 38.0% 좌뇌형 20%였다. Many Studies have demonstrated that the two hemispheres are functionally specialized in the majority of individuals, so that the left hemisphere regulates verbal-analytic cognitive abilities while the right hemisphere predominates in spatial-synthesis abilities. This research program have proceeded about the tendency of hemisphere specialization in sportsmen and variable subject classes in university. Sinagawa's questionnaire method was used as the instrument for this study . The results obtained were as follows: 1. In the physical education class(163subjects) 45.6%(male) and 41.6%(female) of the subjects were regarded as the left hemisphere dominant type, 47.4%(male) and 44.3%(female) of them were bilateral and 7%(male) and 14.2%(female) of them were regarded as left hemisphere dominant type. 2. In the representatives (mational players) group, very similar frequencies were shown except in the left hemisphere dominant type, whose percentile distributions appear as 12.9% in males and 12.6% in females. 3. Extremely higher frequency was shown in right hemisphere dominant type in the male students of medical science class : 63.5% of them were right, 24.9% were bilateral and 11.6% were left hemisphere dominant type. 4. The frequencies of the literature class also were shown very similar patterns with those of other female classes.

청소년의 식이행태 조사 : 서울·양평 두 지역간 비교 The Comparison of Urban and Rural Areas

최준호,안동현,최보율,강윤주,백영석,조연규,고복자,남정현 漢陽大學校 精神健康硏究 1998 精神健康硏究 Vol.17 No.-

방사선 치료를 받는 암 환자들의 사회적 지지와 삶의 질과의 관계

정주희,류소연,윤혜은,남택근,오윤경,안현옥,박계남,이영선 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

Objective : This study was performed to investigate the relationship between social support and quality of life among cancer patients receiving radiation therapy. Matehals and Methods : The data were collected from 98 patients, who were receiving radiation therapy at two university hospitals located in GwangUJu, used by structured questionnaire. For statistical analyses of the association between quality of life and various characteristics, data were analyzed using t-test, ANOVA, Pearson 's correlation, and multiple regression analysis. Results: 1. There were 56(57.1%) males and 42(42.9%) females. Age ranged from 21 to 82 years. The primary sites of cancer were gastrointestinal tract (24.5%), lung (23.5%), breast (21.4%), and head and neck (11.2%) in order. 2. The mean scores of social, family, and medical support were 4.30 0.58, 4.49 0.78, 4.11 0.65, respectively. The score of quality of life was 5.83 1.63 (range: 1.95 ~ 9.05). 3. An analysis of the association between several factors of patients and quality of life showed that the statistically significant factors were age, the presence of distant metastasis, family support, medical support and social support. 4. As a result of the multiple regression analysis, only social support was significant (β=0.932, P=0.02) with quality of life, but age and presence of distant metastasis were not significant. Conclusion : This suggests that quality of life in cancer patients could be improved by strengthening the social support which consists of family and medical support. Further study would be necessary to evaluate separately several aspects of quality of life among cancer patients.