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      • 장기간 항갑상선제 투여 후 임의 중단 뒤 재복용시 발생한 무과립구증 1 예

        김승만;김태영;박수영;배영환;서영경 정은주;김태균;권민정;박정현;이순희 인제대학교 2011 仁濟醫學 Vol.32 No.-

        Agranulocytosis, one of the major side effects of antithyroid a gents, probably occurs in less than 0.25% of cases treated with antithyroid agents. It usually occurs within the first several weeks or months after the initiation of therapy, when drug dosage is higher. Most reported cases of agranulocytosis have occurred during the first 3 months of therapy. We describe here a rare case that did not experience the side effect for 6 years of antithyroid agent treatment but presented with agranulocytosis in one month after re-exposure. It suggests that the major side effect such as agranulocytosis can occur in patients who had undergone prior uneventful antithyroid drug therapy.

      • 바터 팽대부에 생긴 유암종 1예

        강명주,지삼룡,박석주,이재익,조영완,김준영,박성재,박은택,이연재,이상혁,설상영,배상균 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Carcinoid tumors have been reported in a wide range of organs but most commonly involve the lungs, bronchi and gastrointestinal tract. Within the gastrointestinal tract, appendix is the most common location for carcinoid, followed by the distal small intestine, the rectum, and the stomach. Among these, primary involvement of the ampulla of Vater is extremely rare. We report a case of carcinoid tumor of ampulla of Vater. A 62-year-old man presented with epigastric soreness. Gastroduodenal endoscopy showed hyperemic bulging mass on ampulla of Vater and diagnosed as carcinoid tumor by histologic finding, with immunohistochemical study. In ^(111)In-octreoscan, tumor had regional lymph node metastasis, but no evidence of distant metastasis. Pancreatoduodenectomy with lymph node dissection was performed.

      • KCI등재후보

        참당귀의 흰쥐 4-Vessel Occlusion 전뇌허혈에 대한 신경방어효과

        김영옥,하니나,부영민,박선영,박주영,유영법,신준식,안덕균,김호철 대한본초학회 2002 大韓本草學會誌 Vol.17 No.2

        Objectives : Angelicae Radix, the root of Angelica gigas N_AKAI (Umbelliferae) , which has been used to nourish the blood(補血), regulate menstruation(調經), relieve pain and promote bowel movements(崩漏) and activate blood circulation for the treatment of fatigue, headache, constipation and blood troubles in traditional Korean medicine. It's flavour and channel tropism is sweet(甘), pungent(辛), warm(溫), acting on the lung, heart and spleen(肺, 心, 脾). The purpose of study we report here was to determine the neuroprotective effect of Angelica gigas on global ischemia induced by 4-vessel occlusion in Wistar rats. Methods : Angelica gigas extracts was lyphilized after extraction with 85% methanol. We induced 4-VO for 10 minutes and reperfused again. The number of CA1 pyramidal neurons were counted after 7 days of reperfusion under the cresyl violet staining. Results : The results showed that Angelica gigas had significantly neuroprotective effects (100, 250 and 500mg/kg of AR extracts, p<0.001) compared with control group. Each neuroprotective ratio was about 66.1, 79.3 and 78.6% respectively. Immunohistochemical data partially explained the protective effects of Angelica gigas via attenuation of COX-2 induction in hippocampus. Conclusion : Angelica gigas gas neuroprotective effects on the global ischemia induced by 4-vessel occlusion in Wistar rats and the attenuation of COX-2 induction is thought to be its possible mechanism.

      • 잠김 금속판을 이용한 경골 골절의 치료에 대한 임상적 경험 및 초기 결과

        권영호,정구희,박영균 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

        Background : By this study, we evaluated the efficacy of locking compression plate in the treatment of a fractured tibia. Materials and Methods : eighteen tibial fractures were treated by percutaneous plating with locking compression plate. They were composed of nine cases of proximal fracture, two cases of comminuted shaft fracture and seven cases of distal fracture. The results were retrospectively evaluated by the knee and ankle joint motion and walking ability. Results : All fractures were healed except one. The average time for fracture healing was 16.5 weeks(range, 8-24 weeks). Complications included a genu valgus case, but there was no complication of superficial or deep infection. All patients had the recovery of knee and ankle joint motion to the level of pre-injury and could walk without crutch. Conclusion : The locking compression plate(LCP) enables the minimally invasive percutaneous plating technique to fix the tibial fracture and can be selected for the tibial fixation, especially comminuted or metaphyseal fracture because the fixed angle stability of LCP is sufficient to maintain the fracture stability and early joint motion.

      • 한국산 길쭉먼지벌레족의 수리분류(Ⅱ)

        朴鐘均,權容正 慶北大學校農業科學技術硏究所 1996 慶北大農學誌 Vol.14 No.-

        韓國産 길쭉먼지벌레族을 대상으로 "NC" 값을 인정하지 않은 상태에서 定性的 形態形質을 根據로 表現論的 數理分類方式을 利用한 群分析을 실시하였다. 그 結果, 비록 일부 種에서는 傳統分類 結果와 다소 一致하지 않은 경우도 있었으나 대부분 經驗的 分類와 類似한 傾向을 나타내었다. 그리고 대부분 種들이 期待한 屬 또는 亞屬내에 分布하였다. A numerical taxonomy based on the phenetic characters of 59 Korean Pterostichini species is conducted to determine the effect on the assessment of the 7 different methods combined by 3 similarity or dissimilarity coefficients. using 87 morphological multistate characters.

      • SCOPUSKCI등재
      • KCI등재후보

        일부 부인과 양성 질환자의 지방조직 및 혈청의 PCBs와 DDE 농도

        박성균,이강숙,노영만,구정완,민선영,한진구,고원경,김미란,정재근,이종승,김진홍 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

        목적 : 본 연구는 지방조직과 혈청의 PCBs와 DDE 농도를 측정하고, 이에 영향을 미치는 것으로 알려진 요인들과의 관련성을 평가하고자 하였다. 방법 : 유방암, 자궁내막증 등 유기염소계 화합물의 영향이 있는 것으로 알려진 호르몬 관련 질병을 제외한 부인과 환자 52명을 대상으로 지방조직과 혈청을 분석하였으며, 설문조사를 통하여 연령, 교육수준, 직업, 비만도, 흡연과 음주, 출산력, 수유력등을 조사하였다. 지방조직과 혈청의 PCBs와 DDE 농도는 가스크로마토그래피를 사용하여 측정하였다. 결과 : 지방조직의 경우, 13개 PCBs congeners 농도의 합은 중앙값이 48.29 ng/g, 기하평균값이 56.78 ng/g이었고, DDE 농도는 중앙값이 142.89ng/g, 기하평균값이 117.06 ng/g이었으며, 혈청의 경우는 PCBs congeners 농도의 합은 중앙값이 4.67 ㎍/L, 기하평균값이 4.85 ㎍/L이었고, DDE 농도는 중앙값이 1.75 ㎍/L, 기하평균값이 2.09 ㎍/L로 나타났다. 지방조직과 혈청의 DDE 농도 사이는 높은 상관성을 보였으나(r²=0.310, p=0,0002), PCBs는 상관성이 약한 것으로 나타났다(r²=0.029, p=0.2582). 영향요인을 범주화한 후 로그변환 시킨 지방조직과 혈청의 PCBs, DDE 평균의 차이를 분석한 결과, 지방조직의 DDE만이 출산자녀수(p=0.015), 초산연령 (p=0.014), 비만지수(p=0.035)와 연관성이 발견되었다 다중회귀분석의 결과 지방조직의 DDE는 출산자녀수가 적을수록, 초산연령이 늦을수록 증가하는 경향을 보였다. 결론 : 출산자녀수와 초산연령, 비만도가 지방조직의 DDE와 관련성을 보였으며, 또한 유기염소계 화합물의 장기간의 노출에 의한 영향을 평가하는데 있어서 혈청보다 지방조직이 더 유용한 생물지표임을 알 수 있었다. Objectives : This study was purposed to determine the levels of PCBs and DDE in adipose tissue and serum and to evaluate the relations with factors affecting these levels. Methods : We analyzed adipose tissues and sera from 52 gynecologic benign disease patients aged 27-78 years, except hormonal diseases such as breast cancer and endometriosis. We also surveyed age, education, occupation, body mass index (BMI), smoking, drinking, number of children, and duration of breastfeeding by questionnaires. Tissue and serum levels of PCBs and DDE were measured using gas chromatography. Results : The median and geometric mean levels of PCBs were 48.29 ng/g, 56.78 ng/g for adipose tissue and 4.67 ㎍/L, 4.85 ㎍/L for serum, and those of DDE were 142.89 ng/g, 117.06 ng/g for adipose tissue and 1.75 ㎍/L, 2.09 ㎍/L for serum, respectively. Adipose tissue and serum levels for DDE showed high correlation (r²=0.310, p=0.0002), but those of PCBs didn't (r²=0.029, p=0.2582). In analyses of the differences of the means of log transformed adipose tissue and serum PCBs and DDE levels for groups of potential covariates, only adipose tissue DDE levels were significantly associated with number of children (p=0.015), age at first birth (p=0.074) and BMI (p=0.035). In multiple regression analysis, adipose tissue DDE levels were significantly increased with decreasing number of children and increasing age at first birth. Conclusions : This study suggested that parity and adiposity were associated with levels of DDE in adipose tissue, and adipose tissue is a better biomarker than serum for evaluating the long-term exposure of organochlorines.

      • 중학교 Ice-Hockey선수와 축구선수의 체력과 심폐기능에 관한 비교 연구

        박영균,문재형 경희대학교 체육과학연구소 1996 體育學論文集 Vol.24 No.-

        The purpose of this study was to investigate difference of the physical fitness and the cardiorespiratory function between some trained soccer and ice-hockey players. The subject are 15 persons. The results of this study are as fellow: 1)No significant difference appered in terms of the height between the 2 groups. In the weight and chest, there was a significant difference(p〈0.01) between the soccer and ice-hockey player. 2)No significant difference appered in terms of grip strength(right), leg strength extension between the 2 groups. In the grip strength(left), back strength, it showed that there was significant difference(p〈0.05) between ice-hockey player(30.93±7.44kg, 84,80± 17.82kg), and soccer player(26.03±4.86kg, 72.13±15.93kg). In the left and right arm strength flexion, it showed that there was a significant difference(p〈0.01) between ice-hockey player(25.40±6.99kg, 25.13±8.21kg) and soccer player(18.53±3.40kg, 18.13±2.59kg). 3)No significant difference appered in terms of sit-up, sargent jump, trunk flexion between the 2 groups. In the jumping & stepping test, it showed that there was significant difference(p〈.05) between ice-hockey player(22.73±8.21cm) and soccer player(24.13 ±1.92cm). 4)In the Ventilation, It showed that there was a significant difference(p〈0.01) ice-hockey player(11.18±3.15ℓ/min) and soccer player(8.09±1.79ℓ/min) at rest. In maximum VE, It showed that there were no remarkable difference between ice-hockey player(85.10±21.15ℓ/min) and soccer player(94,72±23.14ℓ/min). 5)In respiration rate, It showed that there were no remarkable difference between ice-hockey player(15.13±2.90n/min, 60.53±9.72n/min), soccer player(12.53±2.97n/min, 63.87±7.50n/min) at rest and maximum exercise. 6)In the Heart Rate, It showed that there was a notable difference(p〈0.05) between ice-hockey player(74.47±9.21beats/min) and soccer player(65.94±7.97beats/min) at rest. In maximum Heart Rate, It showed that there was a notable difference(p〈0.05) between ice-hockey player(180.50±11.34beats/min) and soccer player(189.62±9.84beats/min). 7)In the Oxygen intake per weight per min, It showed that there were no remarkable difference between ice-hockey player(5.17±0.85㎖/kg/min) and soccer player(4.83±1.01㎖/kg/min) at rest. In maximum VO2/W, It showed that there was a significant difference(p〈0.01) ice-hockey player(44.10±8.21㎖/kg/min) and soccer player(54.60±4.35㎖/kg/min). 8)In the all-out time, It showed that there were no remarkable difference ice-hockey player(974.00±217.77 sec) and soccer player(1059±241.82 sec).

      • KCI등재후보

        외과적 보조의 급속상악확장술 : 치험 5예 REPORT OF 5 CASES

        박충열,이용욱,송종운,김영운,박홍주,오희균,유선열,이기현,황현식 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.1

        Five adults (3 cases of bilateral posterior crossbite, 2 cases of unilateral posterior crossbite) with intermaxillary discrepancy of over 5㎜ due to maxillary transverse deficiency were treated by surgically assisted rapid maxillary expansion (SARME). Bilateral maxillary horizontal osteotomies, osteotomies of pterygomaxillary junction and anterior lateral nasal wall, ans anterior palatal osteotomy were performed in 4 cases, and unilateral osteotomies in 1case, followed by palatal expansion with tooth-borne orthopedic applicance. No significant complication was observed. The mean palatal expansion was 7.2㎜ (5.8∼10.0㎜) in the maxillary first molar region. During the mean follow-up period of 4 years (5 months∼8 years 7 months), no recurrence of crossbite was observed in all cases. The SARME seemed to be a simple, stable, and reliable procedure for achieving a permanent increase of over 5㎜ in skeletal maxillary transverse width of adults.

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