In situ 고상 에피택시 방법에 의한 CoSi₂/Si(111)구조의 형성

이정주,강민성,김현수,최치규,이운환,이종덕,이영백,김건호,이정용 濟州大學校 基礎科學硏究所 1996 基礎科學硏究 Vol.9 No.2

초고진공에서 공상에피택시(solid-phase epiyaxy, SPE) 방법으로 CoSi₂를 Si(111)기판 위에 에피택시 성장시켰다. 2MeV⁴He++ ion후방산란 분광기와 사중결정 x-선 회절기 및 고분해 투과전자 현미경을 이용하여 성장된 CoSi₂의 상과 조성, 결정성, 그리고 계면의 미시구조를 조사하였다. 초고진공상태의 실온에서 Si(111)-7X7기판에 Co를 약 20 ~50 ?? 중착한 후 SPE에 의하여 실리사이드를 형성시키는 경우 600℃에서는 B-형의 CoSi₂가, 그리고 700℃에서는 A형의 CoSi₂가 선택적으로 에피택시 성장하였으며, 정합성은 B-CoSi₂[110]//Si[110] and CoSi₂(111)//Si(111)이, 그리고 700℃에서는 A-CoSi₂[110]//Si[110], CoSi₂(002)//Si(002)을 나타내었다. Epitaxial films of CoSi₂were grown on Si(111) substrates by in situ solid-phase epitaxy in a ultrahigh vacuum. The phase, the chemical composition, the crystallinity, and the microstructure of the Silicide/Si interface were investigated by 2-MeV⁴He++ ion-backscattering spectrometry, quadruple crystal X-ray diffractometry, and high-resolution transmission eletron micorscopy. High-quality films of either B-type or A-type CoSi₂ could be grown selectively on Si(111) substrates by depositing ~ 20 ~ 50 ?? of Co on a Si(111)-7X7 substrate followed by in situ annealing at 600℃ or 700℃ for 10 min. The matching face relationships are CoSi₂[110]//Si[110] and CoSi₂(111)//Si(111) by B-type CoSi₂ and CoSi₂[110]//Si[110]//Si[110] and CoSi₂(002)//Si(002) for A-type CoSi₂.

급성백혈병의 화학요법에서 조혈간세포 보충요법

이규보,배선근,손상균,이재태,이건수,이경혜,서장수 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1

1. 목적 급성백혈병의 화학요법에 있어서 관해유도 요법시에 보다 더 강력한 항암화학요법을 시행하고 골수억제의 회복을 위하여 말초혈액에서 채취한 조혈모세포의 투여로 그 효과를 증대시키고자 시도하였다. 2. 방법 관해유도 화학요법후에 골수억제시기로부터 회복단계로서 백혈구감소증이 호전도면서 단핵세포가 증가될 때에 말초혈액에서 조혈간세포(stem cell)로 인정되고 있는 CD34+세포의 함유량이 1% 이상되는 시기를 찾아내고 그 때부터 평균 4차례의 단핵구를 분리채집을 하여 -74。C에 냉동보관하였다가 제2차 화학요법후에 해동시켜서 정맥주입하였다. 3. 결과 대상 급성백혈병환자는 6명에 23회의 조혈간세포를 함유한 단핵구 채집을 시행하였고 유효한 단핵구의 채집은 4례에서 가능하였고 2례에서는 유효한 채집이 못되었다. 채집효율은 39.0-74.5%로서 평균 49.8%였다. 채집 후에 혈액학적 변화는 혈색소의 약간 감소 (평균 1.34g/dl)와 혈소판의 감소 (평균20.25%)를 나타내었다. 해동 단핵구를 투여할시에 일과성인 불쾌감, 기침, 흉부압박감, 호흡곤란 등이 있었다. 4. 결론 자가골수이식에서 자기말초혈액조혈간세포이식으로 관심이 이행되는 현시점에 자가조혈간세포를 채집하여 수혈하는 기술이 확립되는 기초를 이루었다고 본다. 이번 대상들은 재발된 금성백혈병들에 시행하였으나, 향후에는 초발시에 제일차 관해유도 화학요법 과정에 시도해야할 것으로 생각한다. Object: Peripheral blood stem cells(PBSC) were collected after remission induction chemotherapy and reinfused after intensified chemotherapy in order to increase the chemotherapeutic efficacy. Method: Collection of mononuclear cells (MNC) was started when CD34+ cells above 1% and WBC above 1,000/ul with mononuclear cell percentage above 30%, the collection procedures were done 2-6 time in each patient of total 6 cases. The collected MNCs were stored in - 750C and reinfused after thawing in the water bath at 370C Results: Twenty three collection procedures from the 6 cases of acute leukemia had made effective MNC collection in 4 cases and mean collection efficiency was 49.8%(from 39.0% to 74.5%). Hematological changes after the procedure were mean reduction of hemoglobin 1.34g/dl and mean 20.25% of decreased platelet count. There were noticed transient symptoms of discomfort, coughing, chest tightness and dyspnea in association with the infusion of stored cells. Conclusion: The basic process for the peripheral blood stem cell transplantation (PBSCT) was accomplished with this supportive care for the consolidation chemotherapy of acute leukemia. Effective PBSCT would be warrented with more qualified process and high does chemotherapy. (Korean J Blood Transfus 6(2) : 41~47,1995)

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

EC속에서의 제언어들의 경쟁, 불어·독어 공용 사용국인 스위스 모델 연구

이건수 서울대학교 국제지역원 1994 국제지역연구 Vol.3 No.2

마스트리히트(Maastricht)조약 이후 유럽공동체(EC)는 관세동맹적 성격을 띤 기존의 유럽 단일시장의 추구라는 차원을 넘어 유럽연방을 염두에 둔 정치·경제적 통합체를 향해 힘차게 나아가기 시작했다. 그러나 오랜된 역사와 상이한 문화 그리고 제각기 다른 언어를 가진 여러 민족들이 국경없는 하나의 공동체로 통합하려는 이러한 급속한 움직임속에서, 유럽의 일반대중들이 맞닥뜨리게 되는 최대 난점은 역시 언어문제이다. 기존의 국경개념은 사라졌을지언정 언어경계선은 그대로 남아 제언어들간의 접촉과 경쟁 양상은 더욱 가속화될 전망이다. 이글에서는 장래 유럽공동체속의 언어적 상황을 예견해보는 모델로 독어·불어·이탈리아어·로망쉬어 등 4개의 국어가 있는 스위스의 예를 검토하여 보았다. 왜냐하면 스위스는 아양한 언어들간의 법적 평등을 전제로 하여, 언어권역간의 현상유지와 한 지역의 언어적 동질서의 보호를 목적으로 하는 이른바 속지성의 원리(principe de territorialite)에 근거한 다언어 연방국가이기 때문이다. 특히 제네바를 중심으로 하는 불어권과 취리히등의 독어권이 만나 이루어내는 언어경계선상의 2개언어병용(bilinguisme)지역들은 경제력과 정치적 영향력 그리고 무엇보다고 상용인구수에 좌우되는 언어들간의 실제적인 불평등의 현장이다. Since the treaty of Maastricht, bearing the European Union in mind, European Community(EC) has strongly advanced to a politic-economic unity beyond the level of a European single market taking on the characteristic of a customs union. In the radical movement of integrating various peoples with long histories, as well as different cultures and languages, however, the greatest difficulty with which common people are confronted is the problem of language. Even though the concept of a national boundary has disappeared, a language boundary still remains and thus the contact and competition among various languages is expected to be accelerated. Therefore, Swiss, where four national languages of German, French, Italian and Romanche are spoken, has been examined as a language model of EC. For Swiss is a multi-language federal government based on the so-called principle of territoriality which aims at the maintenance of the status quo among various language areas and the protection of linguistic homogeneity in each area. In particular, the districts of bilingualism in the linguistic boundary between the French area centered on Geneva and the German area centered on Zurich are the scenes of inequality where the importance of language is determeined by economic power, political influence and above all the number of the language-speaking population.

석탄폐석으로 제조한 흡착제의 물리적 특성

이상인,송근호,오한기,김종수,이광래 강원대학교 부설 석재복합신소재 제품연구센터 1999 석재연 논문집 Vol.4 No.-

석탄폐석인 선탄폐석과 굴신폐석으로 흡착제를 제조하였으며, 탄화/활성화 조건이 흡착제의 물성에 미치는 영향을 조사하였다. 탄화온도 500℃에서는 제조된 흡착제에 미세공이 형성되지 않았으며, 수증기법에 의한 850℃의 활성화 공정에 의하여 미세공이 생성되었다. 생성된 미세공에 의한 표면적은 전체 표면적의 약 50%를 차지하였다. 활성화된 흡착제의 표면적은 탄화과정만 거친 것보다 2.5배 더 컸다. 이는 활성화공정이 흡착제의 표면적에 미치는 영향이 매우 크다는 것을 의미한다. 굴진폐석으로 제조한 흡착제의 BET 표면적이 선탄폐석으로 만든 것보다 1.7∼2.9배 더 크게 나타났다. Coal waste-based adsorbents were prepared, and the effects of carbonization/activation conditions on the physical properties of the adsorbents were investigated. Two kinds of coal waste, coal-dressing waste and coal-dub waste, were used as raw materials. At carbonization temperature of 500℃, micropores were not formed in adsorbents. However, micropores was about 50% of total surface area. The surface area of activated adsorbent was 2.5 times greater than that of carbonized one. The BET surface area of coal-dub waste based adsorbents was 1.7∼2.9 times greater than that of coal-dressing waste based adsorbents.

말쥐치 가공중 향기성분에 관하여

이종호,최병대,이강호,이근태,김태수 國立統營水産專門大學 附設 水産科學硏究所 1989 수산과학연구소보고 Vol.1 No.-

쥐치의 향기성분을 동정하기 위하여 Likerson형의 연속증류추출 및 탄산가스추출법을 이용하여 휘발성 성분을 동정하였다. 그 결과 중성획분에서 55 성분, pherol성획분에서 4 성분, 염기성획분에서 13 성분 및 ㅅ산성획분에서 10 성분이 분리·동정되었고 중성획분에서는 가열·배소 후 propanol, butanol, octanol, dodecanol등의 alcoholfb 그리고 pentanal, hexanal, 2-methyl-l-propanal, heptenal등의 aldehyde의 함량이 크게 증가하여 flavor 형성에 크게 기여할 것으로 생각되어 진다. 분리·동정된 phenol류는 분자량(m/e) 100~160 정도로 나타났으며, 염기성획분에서는 2-methylpyrazine, 2,5-dimethylpyrazine, 2-ethyl=3,5-dimethylpyrazine 등과 2-methylpyridine등이 동정되었다. 이들과 함께 중성획부에서 동정된 furan류가 가열온도의 증가와 함께 그 함량이 증가하였다. 산성획분에서는 배소시료 구분에서 isoaproic acid 및 caproic acid의 함량이 많았다. Volatile compounds were collected by simultaneous distillation extraction and carbon dioxide method, and analyzed by GC and GC-MS. The neutral fraction obtained from the whole steam volatile concentrate 55 kinds of components, phenolic fraction had 4 kinds of components, basic fraction had 13 kinds of components and 10 kinds of components were in acidic fraction. Alcohols, propanols, butanols, octanols, dodecanols etc. and aldehydes, pentanals, hexanal, 2-methyl-1-propanal, heptenal etc. were highly increased after boiled and roasted. And these compounds were contributed to formation of filefish flavor. The molecular ion peak of phenolic fraction was generally appeared in the range 100 to about 160. From the basic fraction, 2-methylpyrazine, 2,5-dimethylpyrazine, 2-ethyl-3,5-dimethylpyrazine and 2-methylpyridine were identified. The contents of basic compounds and furans obtained from the neutral fraction were increased at the higher heating temperature. The flavor of acidic fraction was influenced by the low molecular as isovaleric and valeric acid.

측두엽 간질에서 F-18-FDG PET에 나타난 측두엽 내외측 부위별 대사의 차이

이명철,이동수,정준기,김현집,송호천,이상건,여정석 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.1

Purpose: We investigated the difference of glucose metabolism of medial and lateral temporal lobes of patients with temporal lobe epilepsy (TLE) utilizing quantitative comparison of regional metabolic activities using asymmetric index. Materials and Methods: We studied 19 pathologically proven mesial TLE and 25 lateral TLE patients. Lateral TLE patients were either normal on magnetic resonance imaging (cryptogenic: n=14) or had structural lesions (lesional: n=11). Asymmetric index (ASI) was calculated as [(ipsilateral-contralateral)/(ipsilateral+ contralateral)]×200. Results: ASI of medial and lateral lobes of mesial TLE was decreased (-16.4±8.3 and -12.7±5.5, respectively). In cryptogenic lateral TLE, ASI of lateral temporal lobe was decreased (-11.8±4.7), whereas that of medial temporal lobe was not decreased (-4.6±6.3). ASI of medial lobe of lesional lateral TLE was -7.3±9.1, which was significantly different from that of mesial TLE (p<0.05). Patients with lesional lateral TLE had evident metabolic d or decrease (ASI: -22±10.5) in lateral temporal lobe. While we could not find the difference of metabolic activity in lateral temporal lobes between cryptogenic lateral TLE and mesial TLE patients, the difference of metabolic activity was significant in medial temporal lobes which was revealed by ASI quantitation. Conclusion: Asymmetric decrease of metabolic activity in both medial and lateral temporal lobes indicates medial temporal epilepsy. Symmetry of metabolic activity in medial temporal lobe combined with asymmetry of that in lateral temporal lobe may give hints that the epileptogenic zone is lateral.

개에서 발생한 신우신염 증례

유건우,이선희,임수정,박형진,김태신,송은식,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2009 動物醫科學硏究誌 Vol.16 No.1

A 6 years old Schunauzer dog (7.2kg, intact female) with history of hematuria for two days was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. Complete blood cell count showed no significant abnormalities and serum chemistry profile showed increased phosphate profile. On urinanalysis, there was evidence of bacterial infection. On ultrasonographic evaluation, irregular renal contour and increased echogenecity, pelvic and uretral dilation, and thickening of urinary bladder wall were observed. Based on these finding, the dog was diagnosed as pyelonephritis. The dog was treated with antibiotics based on antimicrobial susceptibility test results, then successfully resolved after 8 weeks of treatment.

전산화단층촬영에 있어서 X-선 흡수계수의 신뢰도에 관한 실험적 연구

이희우,김건상,박수성 중앙대학교 의과대학 의과학연구소 1985 中央醫大誌 Vol.10 No.4

For evaluation of reliability of CT numbers, one ovoid and three round phantoms, which were filled with pure water and different in their diameters, were scanned under various conditions with five whole body and four head CT scanners. The results were as follows: 1. The ovoid phantom similar to human body in size and shape scanned with whole body scanners revealed stable and relatively correct CT numbers throughout entire of phantom. 2. CT numbers were generally higher in phantoms of round and smaller types. 3. There was definite tendency to show higher CT numbers at peripheral zone of phantoms. 4. With increase of kVp, CT numbers were decreased. 5. By the change in mA and slice thickness, some CT scanners were influenced, but the others were not. 6. CT numbers were not influenced by scan time. 7. CT numbers were not influenced by position of phantom in the aperture of gantry of CT scanner. 8. The bone density had no influence upon CT numbers at the region distant more than 1㎝. In two CT scanners, CT numbers were significantly increased within 1㎝ to bone density higher than 455 Hounsfield Unit. 9. CT scanners from different manufacturers showed different results, but those of same model from same manufacturer revealed similar results.

換率變動과 輸出單價에 대한 聯關性 硏究

이근영,김재수 聖潔大學校 社會科學硏究所 1997 社會科學硏究 Vol.4 No.1

AbstractThis dissertration is to investigate that the pass through effect of the Korean Won-U.S. Dollar exchange rate on the Korean export price since the Korea adopted the managed floating exchange rate system in March 1980. This dissertration has set up the export price determination model of the Korea's exporting firms on the basis of its price discrimination behavior of the domestic markets and overseas markets as well as the characteristics of the Korean industry and trade.