초음파 펄스에코 신호의 3차원 처리

송문호,손상락,조정호,성제중,안형근,장순재 한국비파괴검사학회 2003 한국비파괴검사학회지 Vol.23 No.5

비파괴 시험을 위한 3차원 구조의 초음파 영상에는 다양한 결함을 명백하게 보여줄 수 있을 만큼 상세하고 쉽게 알아볼 수 있는 정보가 제공되어야 한다. 수년 동안 원자력 발전소에서 사용된 금속관에 발견되는 소규모의 균열은 전형적인 결함들인데, 이러한 밀리미터 이하의 균열이나 결함은 최종 3차원 영상에서 묘사되어야만 의미있는 검사가 될 것이다. 향상된 선명도와 그에 따른 결함의 발견 과정의 한 단계로써, 펄스에코(pulse-echo) 초음파를 사용한 3차원 영상제작 기술을 제안한다. 이 기술은 필요한 스캐닝과 펄스에코 데이터의 처리과정을 통한 검사로 3차원 물체의 3차원 영상을 생성하는데, 2차원 위너필터(Wiener filter)에 의해 초음파 빔을 선명하게 하는 기술을 포함한다. 제안하는 위너필터는 빔의 전달에서 펄스에코 데이터를 초음파 빔 방향의 수직방향에 따라 필터링한다. 이 3차윈 처리과정은 결함의 선명성을 증진시키고 사용자에게 3차윈 구조물의 좌우 회전 및 축 회전과 같은 조작 능력을 제공한다. 이러한 조작 능력은 3차원에서 다양한 결함들의 크기와 위치의 분명한 묘사를 가능하게 한다. Infrasonic imaging of 3-D structures for nondestructive evaluation must provide readily recognizable images with enough details to clearly show various flaws that may or may not be present. Typical flaws that need to be detected are miniature cracks, for instance, in metal pipes having aged over years of operation in nuclear power plants; and these sub-millimeter cracks or flaws must be depicted in the final 3-D image for a meaningful evaluation. As a step towards improving conspicuity and thus detection of flaws, we propose a pulse-echo ultrasonic imaging technique to generate various 3-D views of the 3-D object under evaluation through strategic scanning and processing of the pulse-echo data. We employ a 2-D Wiener filter that filters the pulse-echo data along the plane orthogonal to the beam propagation so that ultrasonic beams can be sharpened. This three-dimensional processing and display coupled with 3-D manipulation capabilities by which users are able to pan and rotate the 3-D structure improve conspicuity of flaws. Providing such manipulation operations allow a clear depiction of the size and the location of various flaws in 3-D.

기(氣) 시술(施術)이 노인의 심리상태와 통증에 미치는 효과

장혜숙,이명수,장정원,문성록 한국정신과학학회 2002 韓國精神科學學會誌 Vol.6 No.2

Recently, we reported that Qi-therapy (QT) may be beneficial in reducing negative psychological symptoms, increasing melatonin levels, neutrophil and NK cell cytotoxicity in young subjects. however there is little scientific evidence of their efficacy on the elder subjects, Therefore, this study was designed to investigate the effects of QT on anxiety, depression, fatigue, pam and blood pressure In the elder subjects Ninety-four elderly subjects were randomly assigned to either QT (n=47) or mimic therapy (n=47) groups, Both groups received a ten minute intervention period using the same procedures. With respect to pre-QT, the QT group exhibited a greater reduction in anxiety, depression, fatigue, and pain level compared to the placebo group, From these results, It is suggested that the practical application of QT may exert a positive psychological and physiological effect m spite of the lack of a long-term intervention period However, further research is necessary In order to fully understand the long-term Impact of QI-therapy on psychological health Recently, we reported that Qi-therapy (QT) may be beneficial in reducing negative psychological symptoms, increasing melatonin levels, neutrophil and NK cell cytotoxicity in young subjects. however there is little scientific evidence of their effIcacy on the elder subjects, Therefore, this study was designed to investigate the effects of QT on anxiety, depression, fatigue, pam and blood pressure In the elder subjects Ninety-four elderly subjects were randomly assigned to either QT (n=47) or mimic therapy (n=47) groups, Both groups received a ten minute intervention period using the same procedures. With respect to pre-QT, the QT group exhibited a greater reduction in anxiety, depression, fatigue, and pam level compared to the placebo group, From these results, It is suggested that the practical application of QT may exert a positive psychological and physiological effect m spite of the lack of a long-term intervention period However, further research is necessary In order to fully understand the long-term Impact of QI-therapy on psychological health

Unmet Psychosocial Needs of Patients Newly Diagnosed with Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea

Jung Rock Moon,Chang Kyun Lee,Sung Noh Hong,Jong Pil Im,Byong Duk Ye,Jae Myung Cha,Sung-Ae Jung,Kang-Moon Lee,Dong Il Park,Yoon Tae Jeen,Young Sook Park,Jae Hee Cheon,Hyesung Kim,BoJeong Seo,Youngdoe 거트앤리버 소화기연관학회협의회 2020 Gut and Liver Vol.14 No.4

Background/Aims: Limited data are available regarding psychosocial distress at the time of diagnosis of ulcerative colitis (UC). We investigated the psychosocial burden and factors related to poor health-related quality of life (HRQL) among patients newly diagnosed with moderate-to-severe UC who were affiliated with the nationwide prospective cohort study. Methods: Within the first 4 weeks of UC diagnosis, all patients were assessed using the Hospital Anxiety and Depression Scale (HADS), Work Productivity and Activity Impairment questionnaire, Inflammatory Bowel Disease Questionnaire (IBDQ), and 12-Item Short Form (SF-12) health survey. A multiple linear regression model was used to identify factors associated with HRQL. Results: Between August 2014 and February 2017, 355 patients completed questionnaires. Significant mood disorders requiring psychological interventions, defined by a HADS score ≥11, were identified in 16.7% (anxiety) and 20.6% (depression) of patients. Patients with severe disease were more likely to have presenteeism, loss of work productivity, and activity loss than those with moderate disease (all p<0.05). Significant mood disorders had the strongest negative relationship with total IBDQ score, which indicates disease-specific HRQL (β coefficient: –22.1 for depression and –40.0 for anxiety, p<0.001). The scores of all SF-12 dimensions, which indicate general HRQL, were remarkably decreased in the study population compared indirectly with previously reported scores in the general population. The Mayo score, C-reactive protein level, and white blood cell count showed significant negative associations with the IBDQ score (p<0.05). Conclusions: Psychosocial screening and timely interventions should be incorporated into the initial care of patients newly diagnosed with UC.

S-131 Incidence of Hepatocellular carcinoma in korean screenee with chronic hepatitis B

( Jung Rock Moon ),( Jae-jun Shim ),( Tae-woong Choi ),( Chi Hyuck Oh ),( Soyung Park ),( Yu Jin Um ),( Byung-ho Kim ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

Background: To optimize efficacy of National Liver Cancer Screening Program (NLCSP) for subjects with HBsAg positive, it is crucial to know the incidence of HCC and its predisposing factors in the program. Methods: From January 2010 to December 2014, all the HBsAg positive participants who received at least two or more abdominal ultrasonography under NLCSP were retrospectively enrolled in a single tertiary hospital. Annual incidence of HBV-related HCC was calculated and related clinical factors were investigated. Results: During 5 years, 541 subjects were enrolled. Liver cirrhosis was diagnosed in 212 (39.2%) by ultrasonography or upper endoscopy. Esophageal varices were found in 63 (14.8%). Total bilirubin, albumin, platelets, and aminotransferases were normal in most subjects. HBV DNA were less than 2,000 IU/mL in 356 subjects (79.6%). Mean follow-up time was 2.4 years and 16 new HCCs were diagnosed. Annual incidence of HBV-related HCCs were 980 per 100,000 patient year (1% per year). Subjects more than 60 years old (2.2% per year) had higher risk of HCC development than those under 60 years (0.6% per year, p<0.005). Presence of LC (2.2% per year) also showed higher risk of HCC than LC-free state (0.2% per year, p<0.0001). In cirrhotic patients over 60 years old, the incidence increased up to 3.8% per year.Conclusions: Despite of high rate of antiviral therapy, incidence of HBV-related HCC is not low in participant of NLCSP in Korea. Old age and presence of LC are associated with higher risk of HCC development.

Corrigendum: Unmet Psychosocial Needs of Patients Newly Diagnosed with Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea

( Jung Rock Moon ),( Chang Kyun Lee ),( Sung Noh Hong ),( Jong Pil Im ),( Byong Duk Ye ),( Jae Myung Cha ),( Sung-ae Jung ),( Kang-moon Lee ),( Dong Il Park ),( Yoon Tae Jeen ),( Young Sook Park ),( J 대한소화기학회 2021 Gut and Liver Vol.15 No.1

Irradiation of the Intrathoracic Esophagus : prone versus supine treatment positions

Moon, Sun Rock,Kim, Hye Jung,Won, Jong Jin 圓光大學校 韓醫學硏究所 1992 圓光醫科學 Vol.8 No.1-2

식도암의 방사선치료시 원발병소에 60 Gy이상의 방사선량을 조사하면서 근접한 척수의 조사선량을 46 Gy 이하로 제한하는 것은 식도와 척수의 해부학적 근접성때문에 많은 문제점을 가지고 있다. 치료계획시 환자가 복와위를 취하게하면 식도는 척수로부터 다소 멀어져 치료계획시 잇점이 있는 것으로 알려져 있다. 저자들은 총 10명의 환자들을 대상으로 앙와위와 복와위로 동시에 방사선치료계획을 시행하여 두방법의 장단점을 비교하였다. 각각의 자세에서 조영제를 삼키면서 전후방 및 측방으로 단순촬영을 시행하여 조영제가 차있는 식도의 내강 중심으로부터 척수까지의 거리를 기관분기점(Carina) 및 6 ㎝ 상방, 6 ㎝ 하방과 12 ㎝ 하방의 횡단면에서 계측하였다. 각각의 위치에서의 평균식도전위는 1.6(+0.9) ㎝, 1.3(+0.8) ㎝, 1.7(+1.0) ㎝ 및 1.9(+1.1) ㎝이었고 계측된 총 40위치에서의 전위범위는 0에서 4.3 ㎝ 이었으며 평균전위는 1.6 ㎝ 이었다. 복와위에 의한 치료시 병소부위와 장상주변장기의 선량분포를 비교하기 위해 전예에서 복와위와 앙와위의 삼차원적 산량분포를 6문조사법과 8문조사법을 이용하여 예측하였으며 선량분포의 예측은 전산화 치료계획장치를 이용하였다. 6문조사법이나 8문조사법 모두에서 북와위시 앙와위에 비해 동일한 종양조사선량을 유지하면서 주변장기인 척수의 조사선량을 효과적으로 감소시킬 수 있었다. The treatment of esophageal cancer is made difficult by the close proximity of the esophagus to the spinal cord and the requirement to treat the esophageal target volume to doses greater than or equal to 60 Gy while limiting the spinal cord dose to less than or equal to 46 Gy. By placing the patient in the prone position, the esophagus can be displaced away from the spinal cord. We explored the results of this commonly used technique on 10 patients who have undergone simulation in both supine and prone positions. Both AP and lateral orthogonal radiographs were obtained in both positions. The distance between contrast material in the esophagus and spinal cord was noted in at least four transverse planes through the thoracic esophagus on each of the 10 patients. The four transverse planes were located at 3 cm above the carina, at the carina, 3 cm below the carina and 6 cm below the carina. The mean displacement (±1 SD) of the esophagus away from the spinal cord when the patient was in the prone position compared to supine at each of these levels was 1.3 (±0.8)㎝, 1.6 (±0.9) ㎝, 1.7 (±1.0) ㎝, and 1.9 (±1.1) ㎝. The range of displacement for all 40 displacement determinations was 0 to 4.3 ㎝ with a mean of 1.6 ㎝. To evaluate further the consequences of prone positioning on treatment planning and doses received to target volumes and critical structures, we performed 3-dimensional treatment planning with a patient in both prone and supine position. The requirements were to achieve a tumor volume dose of 60 Gy while keeping the spinal cord dose below 46 Gy. Two types of conventional treatment plans were examined in prone and supine positions. A 6-field plan consisted of delivery of 40 Gy through a large 3-field beam arrangement followed by delivery of 20 Gy through a similar 3-field cone down. An 8-field plan involved the delivery of 30 Gy through AP/PA beams followed by a 3-field beam arrangement to 40 Gy and a subsequent 3-field cone-down for the final 20 Gy. Regarding the primary consideration of coverage of target volume with avoidance of spinal cord, prone positioning was superior to supine positioning whether 6- or 8-field arrangements were used.

Polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like polychlorinated biphenyls in cetaceans from Korean coastal waters

Moon, Hyo-Bang,Kim, Hye-Seon,An, Yong-Rock,Choi, Seok-Gwan,Park, Jung-Youn,Kim, Zang-Geun,Choi, Hee-Gu Springer-Verlag 2009 Toxicology and Environmental Health Sciences Vol.1 No.3

고위험 예후인자를 가진 자궁경부암환자에서 방사선과 Cisplatinum의 동시병용요법

문성록,김홍곤,김혜정 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.1

Twelve patients with high risk group of uterine cervical carcinoma received concurrent chemoradiotherapy with weekly cisplatinum. A patient was FIGO stage Ⅰ-B barrel-shaped, two were stage Ⅱ-A. eight were stage Ⅱ-B, and one was Ⅲ-B. All patients responded to concurrent chemoradiotherapy with eleven complete and one partial responses. Nine of 11 with complete reponse are alive disease free on the completion of follow-up. Overall 3-year survival rate was 75% and 3-year local control rate was 92%. Toxicity for the combination therapy was not excessive. Although follow-up is short, this approach for patients with high risk uterine cervical carcinoma yielded excellent results and was well tolerated.

병기 C 직장암의 근치적수술후 보조적 방사선치료

문성록,김혜정,김귀언 圓光大學校 醫科學硏究所 1992 圓光醫科學 Vol.8 No.1-2

From January 1984 to December 1987, 66 patients with Modified Astler Coller stage C rectal cancer were retrospectively analysed. All patients received complete surgical resection followed by postoperative radiotherapy. The patients were divided into two groups as follows : Ⅰ.Low-dose irradiation group (28 patients received less than 5500 cGy in 6 weeks ; Mean 48.7 Gy). Ⅱ.High-dose irradiation group (38 patients received more than 5500 cGy in 6-8 weeks ; Mean 57.7 Gy). Main purpose of this study is to determine whether or not there was differences in local control and survival between low-dose and high-dose postoperative irradiation group. Low-dose postoperative irradiation group had a 45.0% of 3-year local recurrence free survival and 30.3% of 3-year disease free survival. On the other hand, High-dose postoperative irradiation group had a 69.0% of 3-year local recurrence free survival and 60.2% of 3-year disease free survival. The complications for postoperative radiotherapy had no significant difference between two groups and were acceptable in all patients. On the basis of this study, when considering adjuvant postoperative radiotherapy in stage C rectal cancer, at least minimum of 5500 cGy or more should be delivered in order to have maximum benefit.

컨테이너 보안장치(ConTracer)의 통신 성능 향상에 관한 연구

문영식(Moon Young Sik),최형림(Choi Hyung Rim),이은규(Lee Eun Kyu),신중조(Shin Joong Jo),손정락(Shon Jung Rock),최성필(Choi Sung Pill) 한국통신학회 2012 한국통신학회 학술대회논문집 Vol.2012 No.2