최근 10년간 원광의대병원에서 시행한 소아 심장혈관 수술의 임상적 고찰

윤향석,정수미,최두영,오광수,오연균,김종덕,양현웅,이삼윤,김형곤,최종범,최순호,노병석 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

We reviewed 10 years experiences of the clinical aspects and early postoperative results in 544 pediatric patients(age less than 16 years old). Among them. 529 cases had the congenital heart diseases, and 15 had the acquired diseases. Open heart surgery was performed in 413 patients. 115 cases were treated with non-open heart surgery. 16 with interventional catheterization. Annual increase of the cardiac patients was not significant in recent 10 years, except slight increase in 1994. The mean age of the study patients had been evidently changed to younger year by year. Total mortality rate of the open heart surgery was 6.4%. The cyanotic congenital heart diseases were high in early postoperative mortality by 25.7%, whereas 4% in acyanotic group. The age group less than one month was most highest in surgical mortality(66.7%). There were no deaths in patients with patent ductus arteriosus(103 cases), atrial septal defect(83 cases) or pulmonary stenosis(17 cases). Among 220 patients with ventricular septal defects(VSD). 10(4.5%) were died early postoperatively. In cyanotic group, the patients with pulmonary atresia with ventricular septal defects(PAVSD), transposition of the great arteries(TGA), interrupted aortic arch(IAA), complex cardiac anomalies with isomerism seemed to be most susceptible to an early death.

老齡者의 建康을 위한 生活習慣 實態調査

申東敏,長鳳愚,李揆文,金賢俊,金昌範,崔宗洙,崔鍾晥,李鍾珏,金圭碩,趙庚旭,金鍾聲,朴鍾振 平生體育硏究所 論文集 1987 平生體育硏究所 論文集 Vol.2 No.-

With a view to examining the habit and method in which old people maintain and improve their health, we consulted 551 men and 444 women who were over 65 years old, and concluded as follows: 1. Habit of eating It's been revealed that most of the old people keep a regular eating hour, control the quantity of meal or eat a little food, and prefer vegetables to meat. 2. Mental health Old people feel the necessity for mental health and most of them (about 80%) keep good mental health without becoming pessimistic. Their chief concenrs have turned out to be about their sons and daughters and their own health and finance. 3. Managing Good Health It has been revelaed that old people do not possess any special kind of secret to keep good health but taking plenty of rest, regular meal, and proper exercise, and many of them (about 60%) have been shown to eat invigorant food that they can easily get around their living area. 4. Physical Functions It has been revealed that many old people are conscious of some symptoms about their parts of body and about to percent of them suffers from neuralgia. Some measures like medical aid especially for old people need to be taken as soon as possible. As we have found that the health-keeping method of old people consists plenty of rest, proper exercise, and appropriate nutrition, we can conclude that the recreatonal and culture facilities and programs for keeping old people in good health should be developed. It is also necessary to study food that contribute to their health and develop ways to get rid of the stresses to which they are exposed in their daily life. Presides, it is natural that government found an administrative department to deal with these matters effectively.

간척지 중염답에서 유수형성기 염처리에 따른 벼 생육 및 수량 변화

최원영,이규성,고종철,김상수,김태수 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.3

본 연구는 새계화벼를 공시하여 간척지 중염답(0.3~0.4%)에서 관개수 염농도에 따른 생육 및 수량성을 검토하고자 유수형성기에 5일간 염수를 처리하여 시험한 결과를 요약하면 다음과 같다. 1. 관개수 염분농도가 높을수록 벼 출수는 1~2일 지연되었고, 출수기 지상부건물중은 가벼워졌다. 2. 간장과 수장은 관개수 염분농도가 높을수록 짧아졌다. 3. 관개수 염분농도가 높을수록 수당 립수가 적어 ㎡당 립수가 적었으며, 등숙비율이 낮고 현미 천립중이 가벼워, 쌀 수량은 민물 관개(무처리)의 330㎏/10a에 비해 관개수 염분농도 0.1%는 94%, 0.3%는 85%, 0.5%는 76%, 0.7%는 71%의 수량을 얻었다. 4. 관개수 염분농도가 높을수록 완전립 비율은 낮아졌다. 따라서 간척지에서 중염도 토양(0.3~0.4%)에서 벼를 재배하여 유수형성기에 한발이 닥쳐 저류지 등 염분 농도 0.7%의 물로 5일간 담수하여도 쌀 수량은 29% 정도 감수되고 쌀의 품위도 저하되지만 어느 정도 수량은 얻을 수 있을 것으로 생각된다. This experiment was conducted at the Kyehwado Substation of the National Honam Agricultural Experiment Station(NHAES) RDA, Korea. The experimental field contained 0.38% NaCl in soil solution. The experiment was involved five treatments (control, 0.1, 0.3, 0.5, 0.7%) in a randomized complete block design with three replicates, saline solution was applied only one time at panicle formation stage for 5 days. Saegyehwabyeo, a japonica rice variety was used in this experiment. In yield components, Spikelets number per ㎡ decreased with increasing salinity level, particularly in the 0.7% of saline solution water. This factor affected the most yield reduction among the components. The percentage of ripened grain was inclined to decrease with increasing salinity level. 1,000 grain weight decreased with increasing salinity level but it was lest affected by salinity among yield components. The reduction of milled rice yield decreased significantly with increased saline water level, in detail 6% of yield reduction at the 0.1% saline solution, 15% at the 0.3%, 24% at the 0.5%, and 29% at the 0.7% saline solution level compared with control respectively. Results indicate that the gaining of rice yield could be reliable performance in terms of economical benefit for rice production even though high reduction of yield occurred at high salinity levels on a reclaimed saline soil in Korea.

2D 영상보간:부화소 단위의 에지 검출

최재호,이종수,강금부,양우석 한국센서학회 1998 센서학회지 Vol.7 No.5

In this paper, we present a new interpolation scheme for image enhancement using nonlinear operator. In general, interpolation techniques are based on linear operators which are essentially lowpass filters, hence, they tend to blur fine details in the original image. In our approach, the operator itself balances the strength of its sharpening and noise suppressing components according to the properties of the input image data.

Capsaicin과 Paradol이 구강내 유해자극에 의한 개구반사와 신경흥분 전달에 미치는 영향

최동주,신일영,김중수,이종흔 대한구강생물학회 1988 International Journal of Oral Biology Vol.12 No.2

This study was performed to elucidate the analgesic mechanism of paradol and to compare effects of paradol with those of dihidrocapscaicin(DHC). Rabbits(2-2.5kg both sexes) were anesthetized with pentobarbital sodium(30mg/kg I.V.), and cannulated in trachea and external jugular vein. To observe effects on jaw opening reflex, inferior alveolar nerve(IAN) of both sides were exposed for drug application, and wire electrodes were inserted in anterior belly of digastric muscle for recording of EMGs of anterior belly of digastric muscle(dEMG) and in oral mucosa covering mental foramen for applying noxious stimulation. dEMGs evoked by noxious stimulation with double intensity of threshold for digastric EMG were recorded in magnetic tape recorder. To observe effects on action potential, saphenous nerve were exposed, and three tissue pools were made from surrounding tissue. The most distal pool was used for applying stimulation, the most proximal one for recording of action potentials, and the other on for drug application. Action potentials evoked by 200 folds intensity of threshold for most sensitive fiber were recorded in magnetic tape recorder. One side of IAN and saphenous nerves were used for DHC or paradol applications, the other side of nerves for control experiments(only vehicle application). Vehicle consisted of 10% Tween 80, 10% ethanol and 80% physiological saline(v/v), and drugs were solubilized in vehicle for 1.5% concentration(w/v). dEMGs and action potentials were recorded before drug application, immediate after 30 minutes drug application, at 30 and 60 minutes after drug had been washed out. DHC application on IAN could not influence on dEMG, but paradol application decreased the amplitude of dEMG. In action potential experiments, DHC decreased amplitude and conduction velocity of only C fiber, while paradol did those of C-fiber and Aδ-fiber.

데이터 결핍이 있는 자연 영상의 복구에 관한 연구

崔鍾鎬,金仁洙 군산대학교 1989 群山水産專門大學 硏究報告 Vol.23 No.2

We present the new restoration method of natural image with data depletion. The principle of computed tomography is applied to restore the image in time domain. This algorithm estimates the missing information by iterative modifications on the projectional axis and the reconstructed image plane, respectively, using a prior information, i.e, the boundary of missing region, the initial image, and the information of peripheral image. The results of basic simulation show an excellent restored image.

니켈기 초내열합금의 고온부식거동에 관한 연구

최승주,이재현,이찬규,김근수,이종훈 國立 昌原大學校 産業技術硏究所 1998 産技硏論文集 Vol.12 No.-

Hot corrosion behavior of the CMSX-2, CMSX-4, Rene 77, Rene 80 Ni-base superalloys was investigated at 900℃ by two different corrosion methods, immersing the samples in Na2SO4-NaCl mixture(immersion test)and coating the salt mixture on the surface of the samples(modified coating test). The effects of corrosion times and salt compositions from 0 to 100 percent in Na2SO4-NaCl mixtures were examined. Experimental results showed that the corrosion depths in the alloys increased with increasing time, and the depths of the modified coating test were shotter than those of the immersion test in the mixed salt. It was found that the depths of CMSX series alloys increasing NaCl contents in the mixtures up to 50% NaCl. Corrosion products of the alloys were composed of Cr, Al, Ti oxides. The oxide scale, such as Cr₂O₃, Al₂O₃, TiO₂, were shown to improve hot corrosion resistance in the fused Na₂SO₄-NaCl mixtures.

年度別 體育豫算과 競技實績 變化 推移

崔宗洙,鄭升溶,金鍾聲,趙庚旭 忠北大學校 平生體育硏究所 1987 平生體育硏究所 論文集 Vol.2 No.-

The purpose of this study is to investigate between financial support and actual results of sporting game of the Amateur Athletic Association in C-province and the general cities, others provinces. The settled accounts of budget on the C-province Amateur Athletic Association grew to the increased rate of nominal budget than settled accounts of budget inthe previous year, but decreased the settled accounts of real budget think over the rate of raise in prices than the increased of nominal budget. The more the settled accounts of budget on the Amateur Athletics Association-grew, the better the marks obtained of sporting events in a nation athletic meet becamed. Namely, there is a slight growing tendency to bring about good results that the settled accounts of the Amateur Athletic Association budget all of cities, others provinces increased, but didn't absolute.

국내 조혈모세포이식 환자에서 Human Cytomegalovirus gB 유전형의 분포와 질환과의 연관성 : 예비 보고

최수미,김진희,이동건,박선희,최정현,유진홍,박철민,이종욱,민우성,황응수,신완식,김춘추 대한감염학회 2007 감염과 화학요법 Vol.39 No.2

목적 : 사람 거대세포바이러스(Human cytomegalovirus, 이하 HCMV) glycoprotein B (gB)는 UL55 유전자에 의해 부호화되는 당단백으로, UL55 유전자의 염기서열변화에 따라 4가지 유전형으로 나뉜다. 본 연구에서는 국내 조혈모세포이식 환자들에서 HCMV gB 유전형의 분포와 그 특성을 알아보고, gB 유전형에 따라 특정 HCMV 질환 발생과 연관이 있는지 그 임상적 의미를 분석해 보고자 하였다. 재료 및 방법 : 동종 조혈모세포이식 환자 52명의 혈액검체 94개에 대해, Chou 등이 제시한 방법에 따라, 먼저 UL55 유전자 부위를 nested PCR로 증폭한 후, RsaI과HinfI으로 Restriction fragment length polymorphism(RFLP) 분석을 시행하였다. 결과 : gB type 1은 73.1% (38/52), gB type 2는 13.5%(7/52), gB type 3는 1.9% (1/52), gB type 1과 type 2에 의한 혼합감염은 9.6% (5/52)로 나타났다. gB type 4는 관찰되지 않았다. 1명(1.9%)에서 gB 유전형을 결정할 수 없었는데, RFLP 패턴으로 보아 Trincado 등이 제시한 gB type 7에 해당하는 것으로 생각되었고, 이 새로운 아형에 대해서는 현재 염기서열 분석 중이다. 52명 중 5명(9.6%)에서 HCMV 질환이 발생하였고, 3명에서 HCMV 폐렴, 1명에서 망막염과 위장관염, 나머지 1명에서 망막염이 발생하였다. 5명 중 HCMV 질환과 관련하여 사망한 예는 없었고, 감염된 HCMV는 모두 gB type 1이었다. HCMV gB유전형과 HCMV 질환 발생 사이에 유의한 연관성은 없었고, 단일 주에 의한 감염과 혼합감염에 따른 HCMV 질환발생 사이에도 유의한 연관성은 관찰되지 않았다. 자료 분석 중 gB type 2에 감염되어 있던 환자에서 gB type 1에 재감염 되면서 발열, 간효소 수치 상승 및 pp65 HCMV 항원혈증이 나타난 예가 있었다. 결론 : 연구결과 gB type 1이 아주 우세하고, gB type 4는 검출되지 않았으며, 혼합감염의 빈도가 비교적 낮은 분포를 보였다. 이는 외국의 보고와는 다른 국내 조혈모세포이식 환자에서의 독톡한 감염 양상으로 추정된다. 본 연구에서 HCMV gB 유전형과 질환 발생과의 연관성을 밝힐 수는 없었으나, HCMV 유전형에 대한 연구는 바이러스 감염의 발병기전이나 전파 경로 및 양식과 같은 역학적 연구에 중요한 자료가 될 것이다. 현재 더 많은 수의 조혈모세포이식 환자를 대상으로 연구가 진행 중에 있으며, 앞으로 다른 질환군의 환자나 건강한 잠복 감염자에서의 추가 연구가 필요할 것으로 생각된다. Background : Human cytomegalovirus (HCMV) glycoprotein B (gB) is the major envelope glycoprotein, encoded by the UL55 gene. Based on sequence variation in the UL55 gene, HCMV can be classified into four gB genotypes. Previous studies have suggested an association between HCMV gB genotypes and clinical outcome in the immunocompromised hosts. The goal of this study was to determine the distribution of HCMV gB genotypes and the effect of gB genotype in the developement of HCMV diseases in hematopoietic stem cell transplant (HSCT) recipients in Korea. Materials and Methods : DNA was extracted from 94 blood specimen of 52 allogeneic HSCT recipients with HCMV infection. HCMV gB genotype was determined using polymerase chain reaction to amplify a region of UL55, followed by restriction fragment length polymorphism (RFLP) analysis based on RsaI and HinfI digestion. Results : The distribution of gB types were as follows: gB1, 73.1% (38/52) of patients; gB2, 13.5% (7/52); gB3, 1.9% (1/52) and mixed infection (gB1 and gB2), 9.6% (5/52). While gB4 was not detected, a new genotype (described as gB7 by Trincado et al, 2000) was identified on the basis of their RFLP pattern. During average 708 days’ follow up period, HCMV diseases developed in 5 patients. All of them had gB1 genotype. There was no statistically significant association between the incidence of HCMV diseases and the gB genotypes. Re-infection with gB1 strain was detected in one patient who had been previously infected with gB2. This episode was associated with fever, elevated liver enzyme and positive antigenemia. Conclusion : HCMV gB1 was the dominant genotype and no gB4 was detected in allogeneic HSCT recipients in Korea, which is an unique pattern compared with the previous reports. Although we can not find significant association between the HCMV diseases and the gB genotypes, genotyping of HCMV will serve in the study of pathogenesis and transmission of this virus in transplant patients. Further study is underway with large study population.

압자의 압입에 의한 치관 전장용 복합레진의 기계적 성질 평가

최원호,배태성,박광선,박종수 대한치과기재학회 2001 대한치과재료학회지 Vol.28 No.2

This study was performed to evaluate the mechanical properties of four commercially available veneering resin composites for crown (Dentacolor: DC, Artglass: AG, Esternia: ET and Targis: TG). According to the manufacturer's instructions, disc specimens were fabricated in a teflon mold giving 12mm in diameter and 1 mm in thickness. All specimens were immersed in distilled water at 37℃ for 30 days. An indentation test of 68-degree trigonal diamond pyramid was made under 98.06 mN load for 15 seconds. Hardness numbers, charateristic indentation depths, flow and permanent deformation were measured and compared statistically by ANOVA and Tukey's multiple range test. The results obtained were summarized as follows; 1.The highest hardness value of 87.4 was observed in the ET group and the lowest value of 11.8 was observed in the DC group. Hadness values showed no sinificant difference between the AG group and TG group, but others showed the significant difference beween groups (p<0.5). 2.Flow value of the ET group was significantly lower than those of the AG and TG groups of hybrid composite for crowns. 3.Percent strain during the indentation was the lowest in the DC group and the highest in the AG group, but there was no significant difference in each experimental group (p>0.05). 4.The relationship between the hardness number and flow during the indentation was a negative linear on a logarithmic scale.