건축공사시방서에서의 KS규격의 국제인증방안에 관한 연구

김경식,이재섭,김용수,이규진,조용훈,최완철,전재열,이현수,구재동,이기환 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

The purpose of this research is make out construction specifications for International Construction. Using off-shore products incur cost increase and longer delivery term of construction. and inconvenient on International Construction. Expand the range of additional local products conforming to performance. Life Cycle Cost. maintainability. operability. user's acceptability, etc.. And this study is suggest the standard formats and the techniques for construction specification.

Asphalt로 피복된 Portland Cement를 使用한 Concrete의 諸性質

尹錫天,李昌甲,洪元杓,鄭秀永,南宰鉉 충남대학교 공업교육연구소 1982 論文集 Vol.5 No.1

The construction works with concrete has the potential problems of water tightness. The conventional treatments for water-tight concrete are not satisfactory in terms of strength and water tightness. This study was to investigate the effects and application of the asphalt-coated portland cement on water-proof of the concrete and its influences on the physical properties of the concrete. The asphalt-coated portland cement, which is hereafter referred to as ACPC, was made by coating ordinary portland cement with asphalt in the rate of weight ranging from 0.5 to 1.0 percent. In this process, Calcium Chloride and Sodium Silicate were tried as the hardening time accelerator for producing ACPC, and carbon black, talc and other materials were tested for their effectiveness as pore filler. The specimens were prepared and tested with the various amounts of additives as a variable factor to find the optimum material. The analysis was mainly focused at water tightness, physical properties of the concrete and working conditions. The major findings of this experiment are as follows ; 1) Water-proof Test ① The specimens of ACPC and ordinary portland cement(OPC) were tested under the pressures of 3 and 9 kilograms per square centimeter per 24hours respectively and compared. The OPC specimens showed considerable amount of leakaged water while the ACPC specimens were rated lower permeabilities of 89%/28days, 40%/56days and21%/84days under the abovementioned pressure conditions. The most successful composition for water-proof was identified as ACPC added with Calcium Chloride and carbon black. ② The ACPC demonstrated its superiority in absorption test. The absorption amount of OPC for l hour was greater than that of ACPC for 24hours. 2) Compressive Strength Test Four kinds of specimens of ACPC aging 7, 28, 56 and 84days were tested and compared for their respective results of OPC. The ACPC added with carbon black was lower than OPC in compressive strength in the case of curing ages of 7 and 28days but ACPC was superior to the OPC in the specimens aging 56 and 84days. The ACPC added with others except carbon black exposed their lower compressive strength in all circumstances compared with the OPC specimens. 3) Slump Test The slump of ACPC with various additives such as carbon black, talc or clay was 21.6 centimeter which was higher than the OPC of 18.4centimeter slump. This result concluded that ACPC was much favorable in workability in comparison with that of the OPC. The conclusions are summarized as follows; 1) The optimum mixture for water tightness and compressive strength of concrete was found at 0.5% of SACPC, Calcium Chloride and carbon black respectively at the rate of the weight of cement.

S-2 (3-aminopropylamino)ethylphosphorothioic acid (WR-2721)가 방사선에 조사된 흰쥐의 효소 활성에 미치는 영향

고성진,이천복,김재영 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 1997 Journal of biomedical laboratory sciences Vol.3 No.1

S-2 (3-aminopropylamino)ethylphosphorothioic acid (WR-2721)이 방사선에 대한 방어효과에 미치는 영향을 규명하고자 Sprague-Dawley계 웅성 흰쥐를 대조군, WR-2721 단독투여군 (200㎎/㎏), X-선 단독조사군, WR-2721투여 (200㎎/㎏)후 X-선 조사한 병용군으로 나누어 X-선 8 Gy선량을 전신조사한 후 1,3,7,10일 간에 각각 혈액을 채취하여 효소활성치와 glucose함량 변화를 측정하여 다음과 같은 결과를 얻었다. X-선 단독조사군에서는 ALP와 AST의 활성치가 대조군에 비하여 감소하였으나 WR-2721 을 병용한 군에서는 그 감소폭이 줄어들었고, ALT와 LDH의 활성치는 X-선 단독조사군에서 대조군에 비하여 증가하였고, WR-2721을 병용한 군에서는 그 증가폭이 감소되었다. 또한 glucose치의 변동은 X-선 단독조사군에서 대조군에 비하여 유의성 있게 증가하였으나 WR-2721을 병용한 군에서는 그 증가폭이 감소되었다. 이로 미루어 보아 WR-2721이 X-선으로부터 생체내 주요 장기들을 보호하는 작용이 있음을 시사하고 있다. Male rats of Albino strain were divided into four groups, control group, X-irradiated group, WR-2721 treatment group and X-irradiated group treated with WR-2721. The radioprotective effect of treatment with S-2 (3-aminopropylamino)ethylphosphorothioic acid (WR-2721) in the dose of 200㎎/㎏ by intraperitonial injection on rats 20min prior to wholebody X-irradiation (8Gy) was studied. Each group determined serum alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH) activities and contents of serum glucose after 1, 3, 7 and 10 days. The ALP and AST activities of X-irradiated group were significantly decreased (p<0.05) compared with that of control group, but X-irradated group treated with WR-2721 less decreased those enzyme activities compared with the X-irradiated group. X-irradiated group was significantly increased (p<0.05) ALT and LDH activities compared with that of control group, but X-irradated group treated with WR-2721 less increased those enzyme activities compared with the X-irradiated group. The concentration of serum glucose of X-irradiated group was signficantly increased (p<0.05) compared with that of control group, but X-irradated group treated with WR-2721 less increased compared with that of X-irradiated group. It may be considered that WR-2721 provided radioprotective effect of organs of body from X-irradiation.

생리식염수 주입에 따른 점막하층 변화의 실험적 연구

이정환,이상우,이홍식,김창덕,진윤태,최재현,엄순호,류호상,전훈재,현진해,문일환 대한소화기내시경학회 2001 Clinical Endoscopy Vol.24 No.1

Intraductal papillary bile duct adenocarcinoma and gastrointestinal stromal tumor in a case of neurofibromatosis type 1

Lee, Jung Min,Lee, Jae Min,Hyun, Jong Jin,Choi, Hyuk Soon,Kim, Eun Sun,Keum, Bora,Jeen, Yoon Tae,Chun, Hoon Jai,Lee, Hong Sik,Kim, Chang Duck,Kim, Dong Sik,Kim, Joo Young Baishideng Publishing Group Inc 2018 WORLD JOURNAL OF GASTROENTEROLOGY Vol.24 No.4

<P>We report our experience with a synchronous case of gastrointestinal stromal tumor (GIST) and intraductal papillary neoplasm of the bile duct (IPNB) in an elderly woman with neurofibromatosis type 1 (NF-1). A 72-year-old woman presented with a 2-mo history of right upper abdominal pain unrelated to diet and indigestion. Fourteen years earlier, she had been diagnosed with NF-1, which manifested as café au lait spots and multiple nodules on the skin. Computed tomography (CT) revealed a multilocular low-density mass with septation, and mural nodules in the right hepatic lobe, as well as a 1.7-cm-sized well-demarcated enhancing mass in the third portion of the duodenum. The patient subsequently underwent right hepatectomy and duodenal wedge resection. We present here the first report of a case involving a synchronous IPNB and GIST in a patient with NF-1. Our findings demonstrate the possibility of various tumors in NF-1 patients and the importance of diagnosis at an early stage</P>

Interferon-γ가 인체 위암세포의 성장과 세포주기에 미치는 영향

이상우,박민희,이성준,이구,김창덕,진윤태,최재현,엄순호,류호상,전훈재,송치욱,김광희,현진해,유수진,손정원 대한소화기학회 1999 대한소화기학회지 Vol.33 No.1

Background/Aims: The aims of this study were to examine the in vitro effects of IFN (interferon)-γ on growth of human stomach cancer cell lines and to investigate the antiproliferative effects of IFNγ by cell cycle regulation. Methods: Three human gastric cancer cell lines, SNU-1, SNU-16 and AGS, and recombinant human IFN-γ were used. The cells were treated with IFN-γ for various time frames and/or at various concentrations and then, DNA synthesis, cell cycle and the expression of cel cycle regulators were examined. Results: IFN-γ inhibited the proliferation of SNU-1 and SNU-16 in time- and concentration- dependent manners as judged by [3H]-thymidine incorporation assay. In the cell cycle analysis of SNU-1 and SNU-16, IFN-γinduced G1 block at the cell cycle. IFN-γ increased the expression of two or all three of the cycline-dependent kinase (CDK) inhibitors p21WAF1, p27Kip1, and p16INK4, depending on the cell line. Conclusions: These data suggest that the antiproliferative effect of IFN-γ on human stomach ell lines was mediated by increase in the expression of CDK inhibitors and blocking cell cycle at G1-S transition. (Kor J Gastroentero)1999;33:38 - 50)

Effect of hydrophilic group on synthesis of nanosized Ti02 using reverse microemulsion method

( Jai-chun Lee ),( Man Sig Lee ),( Young-bok Lee ),( Sung-woo Moon ),( Gun-dae Lee ),( Seong-soo Hong ) 한국공업화학회 2002 한국공업화학회 연구논문 초록집 Vol.2002 No.1

성인의 간에 발생한 미분화 육종: 증례 보고 및 국내 문헌고찰

이상우,이성준,이구,이광희,이홍식,김창덕,진윤태,최재현,엄순호,류호상,전훈재,송치욱,현진해 대한간학회 1998 Clinical and Molecular Hepatology(대한간학회지) Vol.4 No.3

Undifferentiated sarcoma is one of the rare primary malignant tumor of the liver typically occur ring in later childhood. It has also been referred to embryonal sarcoma or malignant mesenchymoma. In Korea, three child and two adult cases have been reported to date in literature. We experienced a case of undifferentiated sarcoma in a 65- year- old female who presented with abdominal pain and right upper quadrant mass . Contrast-enhanced abdominal CT scan revealed a well demarcated mass with low attenuation and septation at left lobe of the liver and the mass showed hypovascular pattern on hepatic angiography. On cross section, the tumor was well demarcated from the adjacent liver by a fibrous pseudocapsule and showed cystic degeneration. Pathologically, the tumor was consistent with an undifferentiated sarcoma of the liver . (Korean J Hepatol 1998;4:283 289)

소화성 궤양에서 저용량 Clarithromycin 삼제요법의 Helicobacter pylori 박멸률

이상우,권오상,이구,이홍식,김창덕,진윤태,최재현,엄순호,류호상,전훈재,송치욱,허병원,김광희,현진해 대한소화기학회 1999 대한소화기학회지 Vol.34 No.1

Background/Aims: A clear therapeutic regimen for the optimal treatment of Helicobacter pylori (H. pylori) infection has not emerged. We evaluated the eradication rate and side effects of triple regimen with low-dose clarithromycin (0.5 g/day). Methods: One hundred and one patients with duodenal ulcer (n=72), gastric ulcer (n=19), or combined duodenal and gastric ulcer (n=10) were enrolled. H. pylori infection was assessed by histology and rapid urease test before therapy and 4-6 weeks after finishing the treatment of triple regimen. Patients were treated either with omeprazole 20 mg b.d., amoxicillin 1.0 g b.d. and clarithromycin 250 mg b.d. (OAC; n=66) or with omeprazole 20 mg b.d., metronidazole 500 mg b.d. and clarithromycin 250 mg b.d. (OMC; n=35) for 2 weeks. Follow-up endoscopy was performed on 60 patients (OAC; n=41, OMC; n=19). Side effects were evaluated after completion of therapy. Results: Eradication rate of OAC group was 85.4% and that of OMC group was 78.9%. Side effects were observed in 18.2% of the OAC group and 17.1% of the OMC group. Conclusions: Both triple regimens have low rates of side effects. OAC regimen with low-dose clarithromycin shows slightly higher eradication rate of H. pylori than OMC regimen.

간세포암의 예후 및 치료 성적에 관한 연구

이상우,김윤환,이재원,박미라,이성준,이구,김창덕,최재현,엄순호,류호상,전훈재,송치욱,현진해,진윤태,김광희,서성옥 대한소화기학회 1999 대한소화기학회지 Vol.32 No.6

Background/Aims: Recent progress in both diagnostic and therapeutic technique of hepatocellular carcinoma (HCC) appears to improve the prognosis. The purpose of this study was to evaluate the prognosis of HCC in relation to treament methods. Methods: A new staging scheme (PI stage) based on the prognostic index was used. A total of 487 patients with HCC were divided into 4 treatmen groups; no treatment (No Tx), transarterial oily chemoembolization (TOCE), combination of percuta neous ethanol injection and TOCE (CEI), partial hepatectomy (OP). Results: In PI stage I, the groups of CEI and OP showed similar survival rates, and both prolonged survival compared with the group of TOCE. In PI stage II, CEI gave a better survival than TOCE, whereas OP could not improve survival rate, compared with TOCE. In PI stage III, only TOCE was done in some patients and i prolonged survival, particularly when serum bilirubin was 1.5 mg/dL or less. Conclusions: In the P stage I, operation is recommended firstly, but if operation is impossible, CEI could be selected. CE may be chosen as the first treatment choice in PI stage II. In PI stage III, TOCE may be considered for patients whose serum bilirubin is 1.5 mg/dL or less.