Alkylhalide가 Mouse의 LDH isozyme 분포에 미치는 영향 : Cellulose Acetate Electrophoresis Method

권미경,김영옥,박은주,이동화,이명미,이문희,이양자 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

The effect of Carbontetrachloride administration on Lactatedehydrogenase isozyme patterns were analyzed by cellulose acetate electrophoresis for the brain, heart, kidney, lung, liver and mouse muscle. Each other tissue was found to have a characteristic distribution of these isozymes. At normal condition, aerobic tissue such as brain, heart, kidney, and lung were found to have all five isozymes from LDH_1 to LDH_5, while anaerobic tissues such as liver and muscle were found to have superiorly LDH_5 The toxicity of Carbontetrachloride administration was most prominence in the liver, and lung toxicity was occured also.

노인단독가구의 지역사회 건강관리 프로그램 개발

권영숙,이선자 노인간호학회 2005 노인간호학회지 Vol.7 No.2

Purpose: As a preparation for the increase in the number of the aged families, this study was carried out to present health care programs in accordance with the level of self care need of the old of the aged families in one city. Methods: The home visiting survey to the aged families and the documents analysis of the elderly health service of public health centers were investigated. Results: With respect to the self care requisites, the programs were identified to be necessary which are for the improvement of family function, cognitive capability, eyesight and for the control of depression and pain, health education. Conclusion: The developed programs were divided to 'wholly intervention programs', 'partially intervention programs', 'educative-supportive programs'. They are 'expert program'(health visiting program, dementia program) 'self-help program'(senior center supporting program, religious facilities supporting program) and 'health-promoting self-care program (self care program)'.

병원진료 및 서비스에 대한 환자의 만족도 조사연구

權秀子,李英子 서라벌대학 1991 논문집 Vol.5 No.-

The purpose of this study was to investigate the patient satisfaction about curative service in clinical setting. The subjects of this study were 665 patients who were 228 inpatients and 437 outpatients. The data were collected from 10th to 16th, April, 1990 using questionnaire and analized by spss program(percentage, mean score). The results were as follows : A. Inpatients 1. Information & Communication The item which showed the highest level of the patient satisfaction was "number of nursing care" (mean score : 3,32) 2. Hospital Diet The subjects were not satisfied with hospital diet relatively. The item which showed the highest level of the patient satisfaction was "attitude of the hospital diet supplier" (mean score : 3,02). 3. Explanation of the medical or nursing procedure The subjects were not satisfied with explanation of medical or nursing procedure relatively. The item which showed the highest level of the patient satisfaction was "explanation of the received treatment and therapy (mean score : 2.86). 4. Hospital personal attitude The item which showed the highest level of the patient satisfaction was "attitude of the guard" (mean score : 3.33). 5. Hospital facilities The subjects were not satisfied with hospital facilities. The item which showed the highest level of the patient satisfaction was "temperature and humidity" (mean score : 2.60). 6. Regular hour of the curative service The item which showed the highest level of the patient satisfaction was "accuracy of medication timing" (mean score : 3.54). 7. Care of the patient comfort The item which showed the highest level of the patient satisfaction was "explanation of action and side effect received drug" (mean score : 2.92). 8. Cleaning & cleaner The item which showed the highest level of the patient satisfaction was "attitude of the cleaner" (mean score : 3.14). 9. Explanation of follow up care The item of "Explanation of follow up care" was low(mean score : 2.89). B. Outpatients 1. Attitude of the staff with sincerity The item which showed the highest level was "attitude of respction a patient's personality" (mean score : 3.45). 2. Explanation of the curative service The item which showed the highest level was "Explanation of matters that demand special attention" (mean score : 3.25). 3. OPD facilities The item which showed the highest level was "facilities of the telephone booth" (mean score : 3.27). 4. Spending time of the curative service The item which showed the highest level was "spending time of the receipt (mean score : 2.91). 5. Cost of curative service The item which showed the highest level was "cost of drug and therapy" (mean score : 2.78) 6. Guidance of the facilities The item which showed the hughest level was "department of medical treatment" (mean score : 3.46). 7. Incidental facilities The item which showed the highest level was "number of the bench" (mean score : 2.72) 8. Guidance of the receipt and the store The item which showed the highest level was "guidance of the consultation room and the laboratory" (mean score : 3.17).

장기기증 희망자의 의사결정 경험

권영미,윤은자 성인간호학회 2003 성인간호학회지 Vol.15 No.2

The aim of this study was to identify the process of experience toward decision making to donate organs. Method: Eleven subjects who registered at the Association for Organ Sharing in Korea were recruited. Using in-depth interviews and tape-recordings. Data was collected from Jun. 2001 to Feb. 2002 and the contents of these were analyzed by Glaser's grounded theory analysis method. Result: Basic Social- Psychological Problem(BSPP) of subjects were 'attachment to body' and the core theme, that is Basic Socialization Progress(BSP) were discovered to 'find out what is the meaning of life' Also it consisted of four steps: 1st 'hesitate' 2nd 'look into self'. 3rd 'realize the tie up to self' and last 're-find the meaning of life'. Conclusion: These findings indicate the Korean's Basic Socialization Progress of decision making regarding organ donation, so possible development of promoting decision making is necessary strategies for people who is having his/her potential of organ donation in mind.

젖산탈수소효소에 의한 탈수소 반응에 관한 연구

권순자,고영옥 慶熙大學校 1990 論文集 Vol.19 No.-

The kinetics and inhibiton of LDH-catalyzed dehydrogenation of lactic acid were studied to evalute Michaelis constant, Km, maximal velocity, V_max, and inhibition constant, Ki by means of spectrophotofluorometer. The assay condition of reaction mixture was as follows : Lineweaver-Burke plot and found to be 3.4×10^4M and 5.75×10^7M/sec respectively. Reaction medium ◁표삽입▷(원문을 참조하세요) The Dixon and Lineweaver-Burke plot were done to study the effect on LDH of oxalic acid as an inhibitor, whose inhibition constant was found to be 1.26×10^-4M.

간호학생의 간호전문직관과 전공만족, 사회성, 자아존중감간의 관계

권영미,윤은자 대한간호학회 간호행정학회 2007 간호행정학회지 Vol.13 No.3

Purpose: The purpose of this study was to identify the factors influencing the nursing professional values(NPV) of college nursing students. Methods: A convenience sample of 274 subjects was recruited from the department of nursing at a college. The survey was conducted from May 29 to Jun 20 2006. The data was analyzed using descriptive statistics, Pearson correlation coefficients, and stepwise multiple regression with SPSS/WIN 10.1. Results: The average item score of NPV, satisfaction, socialization, self-esteem were 3.60, 3.00, 2.74, and 2.71. The NPV of nursing students showed a significantly positive correlation to speciality satisfaction(r=.28-.46), socialization(r=.13-.46), and self-esteem(r=.12-.15). The significant factors influencing NPV of nursing students were service, curriculum satisfaction, social perception satisfaction, leadership & popularity, and sociability, which explained about 37.5%. Conclusions: Therefore, on the basis of this study's result, when nursing educational programs are developed to make positive NPV, these factors need to be considered.

老人女性의 운동에 대한 認識 및 與件과 實態에 관한 調査硏究

梁順子,權永玉,元周淵 忠南大學校體育科學硏究所 1988 體育科學硏究誌 Vol.6 No.1

The purpose of this study was to provide a fundamental information for plan for positive and active participation or execution of exercise in Female elderly. Questionaire about the Leisure activities, the understanding for exercise and health, the actual and given condition of exercise participation and facilities was used for this study. 330 Aged women (over 60 year-old) who live in Seoul city were answered the Questionaire. Following conclusions were obtained were obtained : 1. Aged women's main daily works are managing house hold duties, attending a lecture in College for elderly, Seeing and Hearing of T. V. or Radio. And their Leisure activities are very simple (not various) and Static, for example seeing and Hearing of T. V. or Radio, gardening, reading, chess and Korean playing cards etc. 2. Aged women are very interested in Health and they point out illness and lack of exercise as a factor of weakness. Furthermore they understand the necessity of exercise for health and their daily life in old age, and also have a lot of intention to do exercise. 3. Exercises that aged women are enjoying or want to enjoy are taking a walk, mountain climbing, physical exercises, Aerobic dance, Badminton, and Jogging. 4. Almost aged women are doing exercise sometimes or usually, and also are seeing and hearing a T. V. or Radio for sports game. 5. Places that aged women are doing excercise are generally not well equipped place (e. g. medicinal water fountain, low hill, and around their house). Besides almost doing exercise alone or just with intimate friends and family. Club sports activities are not general. 6. As inconvinient factor for exercise, a lot of aged women pointed out the not specially equipped or established sports facilities for elderly, lack of number of equipment, and the long distance from home to facilities.

리보플라빈을 가진 수용성 백금(Ⅱ)착체의 합성과 항암활성 및 세포주기와의 관계

황규자,권영이 숙명여자대학교 약학연구소 1999 약학논문집-숙명여자대학교 Vol.16 No.-

A series of vitamine-containing Pt(II) complexes of the type [Pt(Rf)(L)], (where Rf=riboflavin, L=ethylenediamine, 1,3-propanediamine, 1,4-butanediamine) was synthesized and characterized by IR, electronic absorption, elemental analysis and FAB-Mass. The coordination sites of Rf to Pt(II) ions were determined to be N(5) and 0(6) with resultant chelate ring formation. These compouds have much better water solubility(145- 150mg/ml) than cisplatin has(lmg/ml). The anticancer activity of this Riboflavin-containing Pt(II) series was investigated by MTT assay against mouse and human leukemia cell lines in vitro. Interaction between Pt(II) complex and DNA were analyzed by flowcytometry, and showed G2/M arrest in LI210 cell line.

구조화된 환자교육에 대한 연구논문 분석 : 고혈압 환자를 중심으로 forcused on the patients with hypertension

박청자,이경희,고효정,권영숙,김정남,박영숙 대한보건협회 2003 대한보건연구 Vol.29 No.2

This study was conducted to analyze the nursing research methodology and the key concepts used in articles related hypertension published in the RICH. The purpose of this study was for reflecting the trends of the research on the structured patient education focused the hypertensives. The results were as following. 1. There were 119 research studies related hypertension in RICH from 1994 to 2002. The number increased in 1997. Research studies of 98 have done since 1997 and it is 82% of the total research studies. 2. The most of the research studies are non-degree research studies. Research studies with fund have been rapidly increased in 2000 year. 3. The prevailing research design were the non-experimental design, quasi-experimental and pre-experimental designs in order. 4. The data collection method used most often physiologic measures(32.8%). 5. The domain of the key concepts that prevailed was health domain(51.8%), nursing domain(22.9%), and human being domain(20.5%) in order. And environmental domain (4.8%) were relatively low.

염모제 사용에 의한 인체림프구의 DNA 손상 변화

김영철,심미자,권정숙 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.1

To ascertain the effects of hair dyeing application on the DNA damage in human lymphocytes, a mixture of permanent black colored hair dye with the same amount of oxidant containing 6% hydrogen peroxide was used. A hair dyeing with contacting the scalp(conventional dyeing) and a hair dyeing with 3 to 4mm away from the scalp(alternative dyeing) were applied to each 15 young healthy women. Blood was taken from the brachial vein at two sampling times, just before and 6 hours after the hair dyeing, and tail extent moment(TEM) and tail length(TL) were measured by using a comet assay. After dyeing, TL was significantly increased in both conventional dyeing group and alternative dyeing group compared with before dyeing as an average of 47% and 28%, respectively, and TL for conventional dyeing group was higher than alternative dyeing group as an average of 1.2 fold. After dyeing, TEM was significantly increased in both conventional dyeing group and alternative dyeing group compared with before dyeing as an average of 192% and 76% respectively, and TEM for conventional dyeing group was significantly higher than alternative dyeing group as an average of 1.7 fold. Therefore, alternative dyeing application was induced to lower lymphocyte DNA damage than conventional dyeing application, and TEM was appeared to be a more sensitive tool for the measurement of lymphocyte DNA damage than TL in this study.