2-S-Substituted thio-3-aryl-(or-alkyl)4(3H)-Quinazolone 유도체의 합성반응

權純子,金舶重 慶熙大學校 1985 論文集 Vol.14 No.-

A series of 2-S-substituted thio-3-aryl(or-alkyl)4(3H)-quanzolones were synthesized by the following methods using isatoic anhydride or 2-amino-N-substituted benzamides as starting meterials. The intermediates, 3-substituted-2-thio-2,4(1H,3H)-quinazolinediones were prepared by the reaction of 2-amino-N-substituted benzamide with thiourea at high temperature (185-190℃). Then, 2-S-substituted thio-3-aryl-(or-alkyl)4(3H)-quinazolones were synthesized by either the alkylation or the arylation of-3-substituted-2-thio-2,4(1H,3H)-quinazolinediones. The mechanism of the reaction involved in the synthesis was nucleophilic addition with the decarboxylation, cyclization followed by libration of ammonia and alkylation by alkyl halide.

NMR을 이용한 LAS와 AES의 혼합비결정에 대한 연구

권순자,최광훈 慶熙大學校 1980 論文集 Vol.10 No.-

The mixture of alcohol ether sulfate (AES) are linear aekylhenzene sulfate (LAS), raw materials of syndets were reacted with methylene blue (MB). From the NMR spectrum of the products obtained, the mixing ratio of LAS to AES was determined and the presence of branched alkylbenzene sulfate(ABS) in LAS was determined.

PolyG-PolyC 상호작용에 관한 분광학적 연구

權純子 慶熙大學校 1984 論文集 Vol.13 No.-

The Stability of a complex between Poly G and Poly C is determined by measurement of the thermal stability of the complex, e.g. the transition temperature(Tc). The Values for Tc are varied with ionic strength and ionic environment. the stability of the complex also decreases on acylation. Acetylation of 2-amino group of guanine sharply decreases Tc in the thermal hyper-chromicity transition of the Watson & Crick guanine-cytosine hydrogen bond and stacking interaction The Stability of Poly G-Oligo C complex is estimated using Ising Model, by the measurement of Tc Vs. Concentration, Tc Vs. degree of polymerization of Oligomer. Relative stability of hydrogen bond and stacking interaction proves to be guanine - cytocine > adenine - uracil in polymer-oligomer complex.

현대중국어 ‘有些’의 어법화 단계와 기제 고찰

권순자,김현철 중앙대학교 외국학연구소 2024 외국학연구 Vol.- No.70

This study analyzes the stages and mechanisms underlying the grammaticalization of the adverb of degree ‘youxie’ through a diachronic lens. The main conclusions are as follows: First, the grammaticalization of ‘youxie’ progresses through three stages: the initial stage (Song Dynasty), the developmental stage (Yuan Dynasty), and the completion stage (Ming Dynasty). Second, analogy functions as a key mechanism during the initial and developmental stages. The emerging structure ‘you+(xie+AP/VP)’ acquires the meaning ‘to have a slight degree of AP/VP’ by analogy with ‘you+(xie+NP)’. Third, reanalysis operates as the primary mechanism in the completion stage. With the frequent occurrence of ‘youxie+AP/VP’, the structure undergoes a shift: ‘AP/VP’ assumes the role of the predicate, while ‘you’ experiences semantic bleaching and loses its predicate status. This transformation fixes ‘you’ and ‘xie’ as a unified adverbial structure, ‘youxie’, which modifies ‘AP/VP’. Consequently, the reanalysis of ‘youxie+AP/VP’ marks the completion of its grammaticalization as an adverb of degree.

Dihydrojasmone(2-pentyl-3-methyl-2 cyclopentene-1-one)의 합성

權純子,金東秀 慶熙大學校 1982 論文集 Vol.13 No.-

The conversion of nitro group into carbonyl group through basic silica gel is one of the most important and effective methods in synthesizing 1,4-diketone, which is an intermediate to produce dihydrojasmone. In obtaining dihydrojasmone through aldolic condensation of 1,4-diketone, basic silica gel acted as a base catalyst in the activation of hydrogen in α-carbon of carbonyl group. In this study, it turned out that basic silica gel containing 6 mmoles of Na per 9 silica gel produced maximum condensation of 1,4-diketone and optimum reaction time required was 24hrs at 80℃ On the basis of these findings, dihydrojasmone was directly obtained from 1-nitroheptane and methyl vinyl ketone without isolation of 2,5-undecandione through basic silica gel. Relatively high yield of 38.2% was achieved, which was higher than those reported.

연천지역에서 시행한 당뇨병을 진단하기 위한 공복혈당검사의 가치 평가

권순자,박영주,이홍규,신찬수,김성연,박경수,정인경 대한당뇨병학회 1998 Diabetes and Metabolism Journal Vol.22 No.3

Phenylvinylsulfones의 Benzenethiol 첨가물의 합성에 관한 연구

권순자,최준철 경희대학교 자연과학종합연구원 1997 자연과학논문집 Vol.3 No.-

The kinetic study of the hydrolysis of phenylvinylsulfone(PVS) shows that carbon-carbon double bond, if there is an electron-withdrawing group next to it, is apt to have a nucleophilic addition reaction named Michael reaction due to inductive and resonance effect. To apply this mechanism to the addition reaction between PVS derivatives and benzenethiol the reaction was performed in the presence of alkaline catalysts, and the following nucleophilic adducts were obtained and identified : phenyl-2-phenylthioethylsulfone, p-methylphenyl-2-phenyl-thioethylsulfone, p-nitrophenyl-2-phenylth1oethylsulfone, and p-chlorophenyl-2-phenylthioethyl sulfone.

新生兒의 소생법

권순자 대한소아과학회 1971 小兒科 Vol.14 No.12

대전지역 전업 전업주부들의 학력수준에 따른 식품구매 실태조사

권순자,이선영,김경은 한국식생활문화학회 2001 한국식생활문화학회지 Vol.16 No.2

A survey was conducted to assess the food-purchase behavior of 197 Taejon full time housewives 30 to 49 years of age. Food purchase was assessed using a questionnaire and the resulting data were analyzed using SPSS programs. Demographic data revealed that most of the households have three to five family members and that the Engel Indices of the participating households were mostly between 10 and 30%. Noticeable results of the food purchase assessment are as follows. In the grain and grain products items, the low-education group purchased more rice and barley than the high-education group, whereas the high-education group purchased more glutinous rice, brown rice, bread, macaronis and spaghetti than the low-education group. In the vegetable items, the low-education group purchased more Chinese cabbage and radish than the high-education group, while the high-education group purchased more head lettuce, broccoli and sweet pepper than the low-education group. In the meat items, the beef purchase was higher in the high-education than in the low-education group, while the pork purchase was higher in the low-education than in the high-education group. In the processed meat items, ham was the most favorite purchase item regardless of the education level. In the fish and shellfish items, Pacific cod and Alaska pollack were purchased more in the low-education than in the high-education group, and salmon and dried icefish strip were purchased more in the high-education than in the low-education group. No items in fruit group showed significant differences in the purchase amount between the low-education and the high-education group although the latter purchased more imported-fruits such as melons, kiwis, grapefruits, and oranges. Dairy products such as milk, cheese and butter were purchased more in the high-education than in the low-education group. It was also found that both the number of food items and the consumption of foods coming from animals were higher in the high-education than in the low-education group.

Proton Magnetic Resonance Studies of Dipeptides

권순자,이충희,Kwon Soon Ja,Chunghi Rhee Korean Chemical Society 1977 대한화학회지 Vol.21 No.3

Glycine이 포함된 dipeptide인 glycyl-L-valine, L-valyl-glycine, glycyl-DL-alanine, glycyl-DL-serine 및 glycyl-L-aspartic acid의 중수용액속에서의 양성자 자기공명스펙트럼이 실온에서는 pH의 함수로 연구되었다. 이들 스펙트럼의 분석으로부터 $C_{\alpha}H,\;C_{\beta}H\;및\;C_rH$양성자의 chemical shift는 pH에 따라 일단계의 적정곡선으로 변하고 있으며 spin-spin coupling constant는 거의 변하지 않고 있음을 알 수 있다. Dipeptide 용액속에 있는 구성 아미노산의 $C_{\alpha}H\;C_{\beta}H\;및\;C_rH$양성자의 chemical shift가 각각 두개의 다른 값들로 나타나는 것은 이들 용액속에 두개의 자기적으로 서로 다른 site들이 들어있음을 말해준다. 이 연구에서는 다섯개 dipeptide의 구조를 양성자 자기공명스펙트럼에 의해 확인하였으며 결과는 앞으로 oligopeptide에서의 구조 변화, conformation, 구성 아미노산의 순서 결정등을 양성자 자기공명스펙트럼의 분석에 의해 알아낼 수 있음을 암시하고 있다. Proton magnetic resonance spectra of five glycine-containing dipeptides glycyl-L-valine, L-valyl-glycine, glycyl-DL-alanine, glycyl-DL-serine and glycyl-L-aspartic acid in $D_2O$ were investigated as a function of pH at room temperature. From the analysis of the spectra, it was found that the chemical shift of the $C_{\alpha}H,\;C_{\beta}H\;and\;C_rH$protons varies with pH as a one-step titration curve, and that the spin-spin coupling constant remains almost unchanged. Two distinct values of the chemical shift for $C_{\alpha}H,\;C_{\beta}H\;or\;C_rH$protons of constituent amino acids in dipeptide solutions indicate the existence of two magnetically non-equivalent sites in solution. From this study, the structures of the five dipeptides have been confirmed by proton magnetic resonance spectra and it has been suggested that the structural change, conformation and sequence determination can be explored for oligopeptides by an analysis of proton magnetic resonance spectra.