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      • 生物學的 改良劑를 利用한 슬럿지의 脫水

        김형석,신남철,이태호,박승조 동아대학교 환경문제연구소 1991 硏究報告 Vol.14 No.2

        To conditioning sludge to occure in the course of food processing industry, after culturing Rhoodotorula glutinis, dosing a certain amount of culture solution into the sludge and measured the variation of total suspended solids and then, in the aerobic and anaerobic conditions after manage sludge, examining the result of measured specific resitance, the coefficient of cmopressibility to know the dewateability. Arrangements of this result are as follows : 1) As the result of total suspended solids concentration by change of aeration time and the amount of Rhodotorula glutinis dose, optimal dose was Rhodotorula glutinis 10㎖ by 20㎖ sludge. The very suitable aeration time was 4-5days. 2) After dosing biological conditioner(Rhodotorula glutinis) 60㎖ by 11 sludge in aerobic condition, aeration for five days. The results of specific resistance, the coefficient of compressibility were 22.71×10^(5)m/㎏ 1.6, respectively. 3) In the cases of using Rhodotoruls glutinis for biological conditioner, using polymer for chemical conditioner. This results are as follows : Biological conditioner ; the moisture content of sludge cake 77.7% Chemical conditioner ; the moisture content of sludge cake 70.3% But, I author propose that biological conditioner is more useful than chemicals in the total operating and maintenance cost.

      • 라디칼공중합의 속도론. Acrylonitrile/Methyl Methacrylate/Dimethylformamide와 Styrene/Acrylonitrile/Dimethylformamide 공중합계의 체적수축인자

        馬永大,鄭秉訓,南亨錫 단국대학교 1995 論文集 Vol.29 No.-

        The volume contraction factors for the low-conversion copolymerizations of methylmethacrylate/acrylonitrile/dimethylformamide and styrene/acrylonitrile/dimethylformamide at 40℃ have been investigated by the previously developed formulas. The values of the ten parameters necessary to compute the volume contraction factors for each system were determined by measuring the densities of appropriate solutions, and some comments have been made on the individual parameter values. On the basis the results, numerical expressions for the volume contraction factors of the two systems were derived as a funtion of total monomer concentrations. The predicted values of the contraction factors were partially checked against those directly determined by measuring volume vs. conversion curve, and found satisfactory.

      • 好氣性 固定床 生物膜 反應槽의 메디아로 폐칫솔의 利用可能性 檢討에 관한 基礎硏究 : 처리효율을 중심으로

        임채영,김정권,성낙창,신남철,김형석,전기일 동아대학교 환경문제연구소 1997 硏究報告 Vol.20 No.1

        This study was conducted to evaluate the possibility to apply the waste toothbrush to aerobic fixed biofilm reactor for media. The media used for this research was waste toothbrush (WTB) and Pall-Ring. The feed used for this research was synthetic wastewater which was made at the laboratory. The COD, NH₄^(+)- N and PO₄^(-3)-P removal efficiency variations with the organic loading rate was examined at this research. The conclusions drawn from these experiments are listed below : 1. When the influent COD concentration was respectively 300mg/ℓ, 600mg/ℓ, the COD removal efficiency was decreased with the increase of the organic loading rate and the COD removal efficiency for Pall-Ring was higher than the COD removal efficiency was 0.4~1.9%. 2. When the influent NH₄^(+)-N concentration was respectively 13mg/ℓ (COD 300mg/ℓ), 25mg/ℓ (COD 600mg/ℓ ), the NH₄^(+)-N removal efficiency for Pall-Ring was slightly higher than the NH₄^(+)-N removal efficiency for Wastetooth brush. The difference of NH₄^(+)-N removal efficiency was about 0.5~1.5%. 3. When the influent PO₄^(-3)-P concentration was respectively 7mg/ℓ (COD 300mg/ℓ), 14mg/ℓ (COD 600mg/ℓ ), the PO₄^(-3)-P removal efficiency for Pall-Ring was higher than the PO₄^(-3)-P removal efficiency for Wastetooth brush. The difference of PO₄^(-3)-P removal efficiency was about 1.1~2%. 4. COD, NH₄^(+)-N and PO₄^(-3)-P removal efficiencies show very small difference between Pall-Ring and Wastetooth brush as media. So it was showed that wastetooth brush can be used as media very successfully.

      • SCIESCOPUS

        Efficacy and safety of limited endoscopic sphincterotomy before self-expandable metal stent insertion for malignant biliary obstruction

        Nam, Hyeong Seok,Kang, Dae Hwan,Kim, Hyung Wook,Choi, Cheol Woong,Park, Su Bum,Kim, Su Jin,Ryu, Dae Gon Baishideng Publishing Group Inc 2017 WORLD JOURNAL OF GASTROENTEROLOGY Vol.23 No.9

        <P><B>AIM</B></P><P>To evaluate the safety and efficacy of limited endoscopic sphincterotomy (ES) before placement of self-expandable metal stent (SEMS).</P><P><B>METHODS</B></P><P>This was a retrospective analysis of 244 consecutive patients with unresectable malignant biliary obstruction, who underwent placement of SEMSs following limited ES from December 2008 to February 2015. The diagnosis of malignant biliary obstruction and assessment of patient eligibility for the study was established by a combination of clinical findings, laboratory investigations, imaging and pathological results. All patients were monitored in the hospital for at least 24 h following endoscopic retrograde cholangio pancreatography (ERCP). The incidence of immediate or early post-ERCP complications such as post-ERCP pancreatitis (PEP) and bleeding related to limited ES were considered as primary outcomes. Also, characteristics and complications according to the cancer type were classified.</P><P><B>RESULTS</B></P><P>Among the 244 patients included, the underlying diagnosis was cholangiocarcinoma in 118 patients, pancreatic cancer in 79, and non-pancreatic or non-biliary malignancies in the remaining 47 patients. Early post-ERCP complications occurred in 9 patients (3.7%), with PEP in 7 patients (2.9%; mild, 6; moderate, 1) and mild bleeding in 2 patients (0.8%). There was no significant association between the incidence of post-ERCP complications and the type of malignancy (cholangiocarcinoma <I>vs</I> pancreatic cancer <I>vs</I> others, <I>P</I> = 0.696) or the type of SEMS used (uncovered <I>vs</I> covered, <I>P</I> = 1.000). Patients who had more than one SEMS placed at the first instance were at a significantly higher risk of post-ERCP complications (one SEMS <I>vs</I> two SEMS, <I>P</I> = 0.031). No other factors were predictive of post-ERCP complications.</P><P><B>CONCLUSION</B></P><P>Limited ES is feasible and safe, and effectively facilitates the placement of SEMS, without any significant risk of PEP or severe bleeding.</P>

      • Poster Session:PS 1075;Gastroenterology (Gastrointestinal Tract):A Case of Pyloric Gland Adenoma Diagnosed on Upper Body of Stomach

        ( Hyeong Seok Nam ),( Hyung Wook Kim ),( Su Bum Park ),( Young Shin Shin ),( Hong Kyu Lim ),( Ja Jun Goo ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background & Aims: Pyloric gland adenoma, also called adenoma with gastric differentiation, is a rare neoplasm of the gastric mucosa and have reported similar lesions in several organs like the gallbladder, main pancreatic duct, duodenum, rectum and so on. In a retrospective study, 2. 7% of all gastric polyps except fundic gland polyps were pyloric gland adenoma. Although they are rare, they are precancerous lesions and showed frequently identifi ed with concurrent adenocarcinoma. We present a case of a 74-year-old man with a pyloric gland adenoma in the upper body(lesser curvature) mucosa of the stomach. Case Report: A healthy 74-year-old man diagnosed tubular gastric adenoma with high grade dysplasia by biopsy was refered our clinic for further evaluation and management. He presented no symptom and normal lab fi ndings. In endoscopic fi nding, we found 10 mm x 10mm sized fi at elevated lesion with irregular fi ne nodularity and mild central depression. The biopsy result was chronic ulcer. Endoscopic ultrasound revealed focal interruption in submucosa with mass was seen and no abnormal fi ndings in CT. The patient had a endoscopic mucosal dissection(ESD) and histopathology revealed a pyloric gland adenoma with mild dysplasia. The cells are low-columnar and plentiful cytoplasm, the nuclei are round and basally located with minimal nuclear pleomorphism. The cells lacked a well-defi ned mucin cap. Immunohistochemistry showed the tissue to be positive to mucin core peptide 6 (MUC6) and focal strong positive to p53. Conclusion: We reported a case of pyloric gland adenoma on upper body of stomach after ESD which was suspected as gastric adenoma with high grade dysplasia or early gastric cancer.

      • Characteristics of overlooked synchronous gastric epithelial neoplasia after endoscopic submucosal dissection

        Nam, Hyeong Seok,Kim, Hyung Wook,Choi, Cheol Woong,Kang, Dae Hwan,Park, Su Bum,Kim, Su Jin,Choi, Jung Sik Wolters Kluwer Health 2018 Medicine Vol.97 No.39

        <P><B>Abstract</B></P><P>Since endoscopic submucosal dissection (ESD) has been accepted as the treatment of choice for early gastric cancer (EGC) without risk of lymph node metastasis, synchronous gastric epithelial neoplasia is no longer rare in the clinical practice. Knowledge about the characteristics associated with synchronous gastric epithelial neoplasia is of great importance to prevent delayed diagnosis.</P><P>Between November 2008 and December 2014, a retrospective study was conducted in a single tertiary referral hospital. Consecutive patients who underwent ESD due to EGC or high-grade dysplasia were analyzed to evaluate the incidence of synchronous gastric epithelial neoplasia and the factors associated with synchronous and overlooked synchronous lesions.</P><P>A total of 488 patients were analyzed in this study. Synchronous lesions were found in 59 patients (12.1%) during the mean 37.7 months of follow-up. Among 77 synchronous lesions, 25 lesions (32.4%) were overlooked at the time of initial ESD. Age of ≥ 65 years, moderate to severe endoscopic atrophic gastritis, and elevated morphology of primary lesions were associated with synchronous gastric epithelial neoplasia. An important factor associated with overlooked lesions is the non-elevated morphology of lesions.</P><P>Careful endoscopic examination of the whole stomach is necessary in patients who are older and who have moderate to severe atrophic gastritis and elevated morphology of lesions to prevent delayed diagnosis of synchronous gastric epithelial neoplasia, especially non-elevated lesions.</P>

      • The efficacy and safety of minor endoscopic sphincterotomy for biliary stenting

        ( Hyeong Seok Nam ),( Dae Hwan Kang ),( Hyung Wook Kim ),( Choel Woong Choi ),( Su Bum Park ),( Su Jin Kim ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

        Objective: Endoscopic sphincterotomy (ES) is performed to reduce the risk of post-ERCP pancreatitis (PEP) and facilitate the stent placement. But there is still debate the necessity of ES due to potential complications like bleeding. In this study, we evaluated efficacy and safety of minor ES for self-expandable metal stent (SEMS) placement. Methods: From December 2008 to December 2014, we reviewed 244 consecutive patients with malignant biliary obstruction, diagnosed as unresectable malignancies who received SEMSs with minor ES, retrospectively. Early post-ERCP complications including such as PEP and bleeding rate were evaluated. Results: There were 244 subjects with 118 patients from cholangiocarcinoma, 79 patients from pancreatic cancer, 47 patients from non-pancreaticobiliary malignancy. Overall earlypost-ERCP complications occurred among 10 patients (4.1%), including PEP in 7 patients (2.9%, 6 mild and 1 moderate), mild bleeding in 2 patient (0.8%), and mild cholangitis in 1 patient (0.4%). No significant difference in cancer type (cholangiocarcinomaversus pancreatic cancer versus others, p=0.696) and SEMS type (uncovered versus covered, p =1.000) were noted in frequency of post-ERCP complications. Comparison with no complication group (n=234) and complication group (n=10), statistically significant differences were only found in the number of inserted SEMS (p=0.014). Conclusions: The strategy of minor ES could be feasible, safe and effective to facilitate the SEMS placement as not increasing severe bleeding or other complications in patients with malignant biliary obstruction.

      • KCI등재후보

        국소형 선근종증에서 발생한 담낭내유두모양종양 1례

        남형석 ( Hyeong Seok Nam ),강대환 ( Dae Hwan Kang ),최병현 ( Byung Hyun Choi ),김소영 ( So Young Kim ),이정희 ( Jung Hee Lee ) 대한췌담도학회 2018 대한췌담도학회지 Vol.23 No.4

        만성담낭염에 흔히 동반되는 담낭의 선근종증은 육안적 형태에 따라 분절형, 국소형, 미만형의 세가지로 분류할 수 있다. 선근종증에서 드물게 담낭암의 전구성병변이나 담낭암이 발생하기도 하는데, 대부분 분절형 선근종증에서 기원하는 것으로 알려져 있다. 담낭암의 전구성병변 중 하나인 담낭내유두모양종양은 담낭의 점막 상피에서 기원하여 내강 내로 자라면서 용종이나 유두종을 형성하는 것이 일반적이다. 이번 증례에서 담낭 점막의 용종이나 유두종을 형성하지 않고 근육층에 국한되어 있으면서 국소형 선근종증에서 유래한 담낭내유두모양종양 1예를 보고하고자 한다. Adenomyomatous hyperplasia (AMH) of the gallbladder commonly accompanies chronic cholecystitis and may be classified into three types according to the gross features: segmental, localized (fundal), and diffuse types. In situ or invasive carcinomas arising from and confined to AMH are rarely observed, especially of the segmental type. Intracystic papillary neoplasm (IPN) is one of the precancerous lesions of the gallbladder. IPN usually grows into the lumen and produces a polypoid or papillary mass. Here, we report an extremely rare case of IPN arising from and limited to a localized AMH incidentally detected in a brain-dead 68-year-old female patient during organ harvesting. Korean J Pancreas Biliary Tract 2018;23(4):182-189

      • KCI등재

        초음파내시경 유도 담도배액술

        남형석 ( Hyeong Seok Nam ),강대환 ( Dae Hwan Kang ) 대한소화기학회 2017 대한소화기학회지 Vol.69 No.3

        The therapeutic role of endoscopic ultrasound (EUS) has continued to evolve in recent years. EUS-guided biliary drainage (EUS-BD) can be performed as an effective alternative to percutaneous drainage or surgical options when conventional Endoscopic retrograde cholangiopancreatography fails or is not possible. Depending on the access and exit routes of the stent, multiple approaches to EUS-BD have been proposed. Each patient should receive an individualized approach based on the patient`s condition, anatomy, and endoscopist`s experience, with an appropriate backup prepared. In high-volume centers, the cumulative success rate has been reported to be over 90%. However, the reported overall complication rate remains relatively high at 10-30%. Further studies are necessary to better understand the long-term results and standardize EUS-BD, including appropriate indications and optimal approach. (Korean J Gastroenterol 2017;69:164-171)

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