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      • 튀김物의 成分에 의한 튀김油脂의 理化學的 性質變化

        孫賢淑,李惠成 慶北大學校 師範大學 1980 敎育硏究誌 Vol.22 No.-

        The purpose of this study was to clarify the effect of batter ingredients on changes of acid value, iodine value, viscosity and color of frying fat and oil. Batter ingredients which were determined in this experiment were egg, baking powder, dried whole milk, sugar and salt. Batters containing each ingredient were fried in rape seed oil and shortening for 4 hours at 185 ± 5℃ and properties of frying fat and oil were checked each hour. The results were as follows: Generally, acid value, darkening of color and viscosity increased and iodine value decreased with frying time. Batter containing egg influenced most remarkably on changes of acid value and darkening of color in both oil and fat and on change of iodine value in rape seed oil. The batter ingredient which influenced most remarkably on change of iodine value in shortening was dried whole milk and that on change of viscosity in both oil and fat was sugar.

      • KS H ISO 1242 표준의 평가 : 라반딘 정유의 산값 측정

        전혜림,이은지,장혜진,손현화,김건,김남선,전명숙,이동선 서울여자대학교 2010 자연과학연구논문집 Vol.22 No.-

        The acid value (AV) as well as the ester value of essential oil is an important index to evaluate quality of essential oil. The official standard analytical method of KS H ISO 1242 dealing with “Essential oils - Determination of acid value” was assessed experimentally using two lavandin essential oils obtained in France as an example. One French lavandin oil sample showed the results of AV= 0.9 by both indicator method and potentiometry. Another sample showed AV = 1.9 by indicator method and AV = 1.6 by potentiometry. Latter lavandin oil sample exhibited significantly higher acid value than maximum value of 1 described in the standard. This result suggests that latter lavandin oil was contaminated, because this oil was contained in an orange juice bottle. Results of this study proved that KS H ISO 1242 could be used as a suitable scientific standard for the determination of acid value of essential oils.

      • 유아기 그림 유우머 설명정도 및 감지정도와 창의성과의 관계

        백영숙,손혜숙 경인여자대학 1997 경인논집 Vol.- No.6

        The aim of this study is an attempt to understand children more effectively through the relationship between comprehension of pictorial humor and creativity in early childhood. Children's explanation of pictorial humor was analysed to ascertain : (1) the effect of age on the children's explanation of pictorial humor stimuli, (2) the effect of age on the children's appreciation of pictorial humor stimuli, (3) the rating of creativity on children's explanation of pictorial humor and (4) the rating of creativity on children's appreciation of pictorial humor. For this purpose, the explanation of pictorial humor and the appreciation of pictorial humor and integrated creativity were tested. Three major themes were used by Kang(1982). They consisted of themes such as taboo, aggression and sophistication. These themes were used in the current study to construct three pairs of drawings as humor stimuli. The children's explanations of pictorial humor were classified into four categories originally developed by Brown (1993). To measure creativity, the Integrated Creativity Test for four to six-year-old Korean Children developed by Chun (1995) was used. The subjects of this experiment were 90 four to six-year-old children who attended Kindergartens in Seoul and Pundang. The children were individually given the Humor Stimuli and Creativity Test. The analysis of data employed a oneway ANOVA and the Duncan test significance through SPSS/PC+. The results and conclusions of this study are as follows. 1) There were partly significant age differences in the rating of children's explanation of pictorial humor. That is, the six-year-old group showed higher explanation levels than the four-year-old and the five-year-old groups. 2)There were no significant age differences in the rating of children's appreciation of pictorial humor. That is, the higher old age group didn't show higher appreciation levels than lower old age groups. 3) There were significant differences in the explanation levels of pictorial humor in the rating of creativity. That is, the higher explanation levels of pictorial humor group ?? showed higher creativity scores than the lower explanation levels of pictorial humor group children. 4) There were no significant differences in the appreciation levels of pictorial humor in the rating of creativity. That is, the higher appreciation levels of pictorial humor group children didn't show higher creativity scores than the lower appreciation levels of pictorial humor group children. The above-mentioned findings were interpreted and discussed in terms of theoretical background and previous research findings. Some suggestions were presented for further study.

      • 조혈모세포이식 후 골성장인자의 변화 및 골대사에 미치는 영향 : Impact on Bone Mineral Metabolism

        백기현,오은숙,오기원,이원영,김혜수,권순용,한제호,강무일,차봉연,이광우,손호영,강성구,김춘추 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.5

        연구배경: 각종 장기이식의 시행이 많아지고 이식 후 생존율이 증가함에 따라 이식 후 합병증에 대한 관심 또한 높아지고 있다. 조혈모세포이식 후에도 다양한 내분비적 합병증이 발생할 수 있으며 골격에 대한 합병증도 문제점으로 대두되고 있다. 조혈모세포 이식 후 발생하는 골소실에는 이식 후 초기의 골형성 저하와 골흡수 증가가 중요한 역할을 담당하리라고 추측되는데 이러한 골재형성불일치(biochemical uncoupling)에 골 성장인자들이 미치는 영향에 대해서는 알려진 바가 없다. 본 연구에서는 조혈모세포이식 전, 후로 말초 혈액에서 IGF-I, FGF-2, M-CSF같은 성장인자의 변화를 알아보고, 이들 성장인자의 변화가 조혈모세포이식 후의 골형과 골흡수에 미치는 영향 및 이식 후 발생되는 골량 소실과의 연관성을 확인해 보고자 하였다. 방법: 여러 가지 혈액질환으로 인해 동종 골수이식을 시행 받은 환자들을 전향적으로 관찰하였으며 이식 전 및 이식 후 1주, 2주, 3주, 4주 및 3개월, 6개월 1년에 말초 혈액에서 골교체표지자를 측정하였다. 이식 전 및 이식1년 후에 요추골 및 대퇴골 골밀도를 측정할 수 있었던 36명의 환자들을 대상으로 냉동 보관되어 있던 혈청을 이용하여 IGF-I, FGF-2 및 M-CSF를 시기별로 측정하였으며 이들 성장인자와 골교체표지자의 변화 및 골밀도 변화 사이의 상관관계를 확인하였다. 결과: 골흡수 표지자인 혈청 ICTP는 이식 전에 비해 이식 후 4주까지 점차 의의 있게 증가하다가 이후 6개월까지 더욱 증가한 후 감소하였다. 골형성 표지자인 osteocalcin은 이식 후 3주까지는 점차 감소하다가 이후 증가하여 이식 후 3개월 및 6개월에 기저치보다 통계적으로 유의하게 증가한 후 감소하였다. 혈청 IGF-I과 FGF-2는 각각 이식 후 3주 및 1주까지 의미있게 감소하다가 이후 증가하였으며 혈청 M-CSF는 이식 후 1주째에 기저치에 비해 의미 있게 증가하였다가 이후 기저치로 회복되었다. 이식 1년 후 평균 요추부 골밀도는 5.2% 감소하였고 평균 근위대퇴골 골밀도는 11.6% 감소하였다. 이식 전 및 이식 후 3주에 측정한 IGF-I과 같은 시기에 측정한 오스테오칼신 사이에 유의한 상관관계가 관찰되었으며 이식 후 3주째의 M-CSF와 골흡수표지자인 M-CSF 사이에서 의미 있는 양의 상관관계를 관찰할 수 있었다. 이식 후 3주 및 3개월에 IGF-I이 낮은 환자일수록 이식 1년 후 근위대퇴골에서의 골소실이 많은 것으로 분석되었다. 결론: 조혈모세포이식 후 발생하는 골소실에는 기존에 알려진 기저질환의 영향, 성호르몬의 감소, 면역억제의 투여, 골수기질세포와 조골세포의 손상 및 이식초기 사이토카인의 변화이외에도 골성장인자가 관련이 있음을 확인하였고, 이는 이식 후 발생되는 골량소실에 중요한 역할을 할 것이라고 사료된다. Background: A loss of bone mass is usually detected after a bone marrow transplantation (BMT), especially during the early post-transplant period. We recently reported that enhanced bone resorption following a BMT was related to both the steroid dose and the increase in IL-6. We also suggested damage to the marrow stromal microenvironment, by myoablation, partly explains the impaired bone formation following a BMT. It is well known that some growth factor play important role in bone growth and osteogenesis. However, the pathogenetic role of bone growth factors in post-BMT bone loss is unknown and data on the changes in the growth factors, in accordance with bone turnover markers and bone mineral density (BMD) changes are scarce. We investigated changes in bone growth factors such as IGF-I (Insulin-like growth factor-I), fibroblast growth factor-2 (FGF-2) and Macrophage colony stimulating factor (M-CSF), during the post-BMT period, and assessed whether the growth factor changes influenced the bone turnover and post-BMT bone loss. The present study is the first prospective study to describe the changes in bone growth factors following a BMT. Methods: We prospectively investigated 110 patients undergoing a BMT, and analyzed 36 patients (32.4±1.3 years, 17 men and 19 women) whose BMDs were measured before, and 1 year after, the BMT. The serum biochemical markers of bone turnover were measured before, 1, 2, 3 and 4 weeks, 3 and 6 months, and 1 year, after the BMT. The serum, FGF-2, IGF-I and M-CSF levels were measured before and 1 and 3 weeks, and 3 months after the BMT. The correlation between the changes of growth factors and various bone parameters was analyzed. Results: The mean bone losses in the lumbar spine and total proximal femur, calculated as the percentage change from the baseline to the level at 1 year, were 5.2(p<0.05) and 11.6%(p<0.01), respectively. the serum type I carboxyterminal telopeptide(ICTP), a bone resorption marker, increased progressively until 6 months after the BMT, but thereafter decreased, to the base value after 1 year. Serum osteocalcin, a bone formation marker, decreased progressively, until 3 weeks after the BMT but then increased transiently, and finally returned to the base level at 1 year. The serum IGF-I and FGF-2 also decreased progressively until 3 weeks 1 week after the BMT, respectively, then increased to the base values at 3 months. The serum M-CSF increased briskly at 1 week post-BMT, then decreased to the base level. There were positive correlations between the percentage changes from the baseline proximal femur BMD and the IGF-I levels 3 weeks and 3 months (r=0.52, p<0.01, r=0.41, p<0.05) post BMT. A significant correlation was found between the IGF-I and osteocalcin levels pre-BMT, and 3 weeks after the BMT. Another positive correlation was found between the M-CSF and the ICTP levels at 3 weeks post BMT (r=0.54, p<0.05). Conclusion: In conclusion, there were significant changes in the serum IGF-I, FGF-2 and M-CSF levels in the immediate post-BMT period, which were related to a decrease in bone formation and loss in the proximal femoral BMD during the year following the BMT (J Kor Soc Endocrinol 17:664∼674, 2002).

      • KCI등재후보

        다발성 말초신경증이 동반된 불명열로 발현한 혈관내 림프종증

        박병배,김갑현,손준성,기현균,정숙인,오원섭,백경란,정철원,송재훈,고영혜 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

        불명열의 원인에는 감염, 신생물, 교원섬유혈관질환 등의 여러 가지 질환이 속한다. 불명열 환자를 접하게 되면 그 원인을 밝히기 위한 검사를 시행하게 되는데, 수많은 검사를 시행하고도 그 원인 질환이 진단 안 되는 경우가 5-15% 정도 된다. 불명열의 원인으로서 이전까지 진단이 어려웠던 농양이나 종양은 현대의 방사선적 영상기술 발달로 조기 진단이 가능하게 되었지만, 악성 혈액질환처럼 종괴를 형성하지 않는 질환들의 정확하고 신속한 진단은 여전히 어려운 실정이다. 혈관내림프종증은 림프절 병변을 거의 형성하지 않기 때문에 진단이 매우 어려운 질환이다. 병의 경과가 빨리 진행하여 예후가 좋지 않으므로 신속한 진단이 절실히 요구되는 질환이다. 저자들은 말초신경증이 동반된 불명열을 주소로 내원한 환자에서 흉강내시경 폐생검을 시행하여 혈관내림프종증을 조기 진단할 수 있었기에 이를 문헌 고찰과 함께 보고 하는 바이다. Fever of unknown origin (FUO) is caused by infections (30-40%), neoplasms (20-30%), collagen vascular diseases (10-20%), and numerous miscellaneous diseases (15-20%). The literatures also reveal that 5-15% of FUO cases defy diagnosis, despite extensive studies. Diagnostic advances continuously modify the spectrum of FUO-causing diseases. Modern imaging techniques (e.g., ultrasound, CT scan, MRI) enable early detection of abscesses and solid tumors that used to be difficult to diagnose. But the correct diagnosis can be delayed because the tumor, such as rare hematologic malignancy, is difficult to be detected by various imaging studies. Intravascular lymphomatosis (IVL) is a rare form of non-Hodgkin's lymphoma and generally fatal disease characterized by extensive proliferation of neoplastic mononuclear cells within the lumina of blood vessels. The prognosis is usually extremely poor, with rapid death despite chemotherapy. The diagnosis is most frequently made after biopsy of skin or brain but is often established post mortem. Most patients with IVL present with FUO and nonspecific cutaneous and neurologic manifestations. Peripheral nerve system or pulmonary involvements are not common as initial menifestations. We report a case of intravascular lymphomatosis, presenting as FUO with peripheral polyneuropathy. We made early diagnosis of IVL by video-assisted thoracoscopic lung biopsy. She is improving with good performance after the 4th cycle of chemotherapy till now.

      • SCOPUSKCI등재
      • KCI등재

        Cathy Song's Picture Bride as an Ethnic Autobiography

        Hye sook Son,Jae Young Ahn 한국아메리카학회 2014 美國學論集 Vol.46 No.3

        Ethnic autobiography diverges from traditional notions of American autobiographies by re-interpreting the singular 'I' in autobiographies. The speaking subject is no more a confident and firm individual, a successful representation of a prosperous American society. Rather, it shows the complexity and elaborateness of defining oneself in an ethnic context, as it requires the subject to be placed in multiple historical, cultural, economic, and ethnic discourses and circumstances. Just as ethnic autobiography resists unified evaluation of ethnic selves, it is important to note that Picture Bride possesses greater significance than as a mere family poem or a poem about various images of Asian American women. Rather than solely dealing with traditional or radical images of Asian American women, this poem collection places its subjects in multiple historical, cultural, economic, and ethnic discourses and contexts. By presenting collective yet conflicting voices of Asian American women, their conflicts regarding their ethnicity, and irreconcilable images and themes, Picture Bride illustrates the ongoing process of self-formation and representation through its speakers and narrative structures, and presents the complexity and elaborateness in defining oneself in an ethnic context. Analyzing Song's Picture Bride as an ethnic autobiography enables her work to be interpreted on a brooder perspective, allowing us to delineate a clearer map of her poems as an Asian American poetry and to appreciate its significance as well as prominence in the fields of Asian American literature.

      • KCI우수등재
      • SCISCIESCOPUS
      • KCI등재

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