천마(Gastrodia elata Blume)의 항혈소판, 항혈전활성

백영숙,송재경,윤춘희,정교순,윤혜숙,Paik, Young-Sook,Song, Jae-Kyoung,Yoon, Chun-Hee,Chung, Kyo-Soon,YunChoi, Hye-Sook 한국생약학회 1995 생약학회지 Vol.26 No.4

MeOH extract of Gastrodia elata was fractionated to five solvent fractions, hexane fr (fr I), 90% MeOH fr (fr II), EtOAc fr (fr III), BuOH fr (fr IV) and $H_2O$ fr (fr V). Among the five fractions, fr II, III and IV showed platelet anti-aggregating effects against ADP or collagen induced rat platelet aggregation in vitro. Fr II , III and IV were also tested in vivo, in the mouse and rat models of thrombosis. Oral administration of fr II, III or IV enhanced the recovery from the thrombotic shock in the mouse model of thrombosis to 32-40% from 17% of recovery with the control group of mice. Treatment with fr II, III or IV also attenuated the sudden reduction in the blood platelet count following intravenous collagen injection to rat. The above results were indicative of the presence of anti-platelet and anti-thrombotic components in this plant.

제주도 주변 해역 표층퇴적물의 특성 분석 및 비교

백영숙,임동일 대한조선학회 2012 대한조선학회 학술대회자료집 Vol.2012 No.5

급성 폐혈증형 돼지단독예에서 분리한 Erysipelothrix rhusiopathiae의 생화학적 특성 및 약제감수성

백영숙,조길재,김봉환,Baek, Young-sook,Cho, Gil-jae,Kim, Bong-hwan 대한수의학회 1990 大韓獸醫學會誌 Vol.30 No.4

The present study was conducted to investigate biochemical properties and antimicrobial drug susceptibilities of 47 strains of E rhusiopathiae isolated from the cases of acute septicemic swine erysipelas in Youngnam and Kyunggi provinces during the period from June 1988 to December 1989. The isolants were identified as E rhusiopathiae on the basis of cellular and colonial morphology, and characteristic reactions in some biochemical tests. All the organisms produced hydrogen sulfide in triple sugar iron agar and showed the characteristic "pipe cleaner" type of growth in gelatin stab cultures. The majority of biochemical and cultural properties of E rhusiopathiae isolated from pigs affected with acute erysipelas were identical to those of the reference strains employed. All the isolates were highly susceptible to penicillin G, ampicillin, erythromycin (MIC:0.025~0.39IU or ${\mu}g/ml$), and moderately susceptible to oleandomycin, oxytetracycline, chloramphenicol(MIC:$0.78{\sim}25{\mu}g/ml$). Kanamycin and sulfadimethoxine showed no activity against the isolates(MIC:>$400{\mu}g/ml$). The MICs of dihydrostreptomycin presented two distribution peaks; of 47 strains, 5(10.6%) were resistant to dihydrostreptomycin (MIC:$400{\mu}g/ml$), while the majority of them were susceptible to the drug.

제주도 주변 해역 표층퇴적물의 특성 분석 및 비교

백영숙,임동일 한국해양환경·에너지학회 2012 한국해양환경·에너지학회 학술대회논문집 Vol.2012 No.5

강화도 남부 여차리 조간대에서 관찰되는 생흔의 분포와 퇴적환경과의 연관성

백영숙,전승수,김종관 대한지질학회 2009 대한지질학회 학술대회 Vol.2009 No.

정신보건센터 재활프로그램 참여.비참여 만성정신장애인의 자가관리 및 가족부담감 비교 연구

백영숙,정안순,Baek, Young-Suk,Jeong, An-Soon 한국가정간호학회 2011 가정간호학회지 Vol.18 No.1

Purpose: This study propose basic materials to prepare the mentally disabled for rehabilitation nursing mediating plans, by comparing the degree of self-care of the chronically mentally disabled residing in community mental health centers between those who participate in daytime rehabilitation programs and those who do not as well as the degree of perceived burden of the two groups' families. Method: The subjects of the study were 51 chronically mentally disabled men, who participated in daytime rehabilitation programs in three mental health centers in Gyeonggi-do and their families, and 53 in-house chronically mentally disabled men, who did not participate and their families. The measuring instrument for self-care consisted of ten spheres (65 questions and 5 points a standard). To quantify the feeling of burden of families, the measuring equipment developed by Montgomery et al. was used. Results: The degree of self-care of chronically mentally disabled men participating in rehabilitation programs in community mental health centers were higher than that of men not participating, and there was a significant difference between them. Families in the group not participating in rehabilitation programs had higher score than those in the group participating, but there was no significant difference. Conclusion: The participation of the chronically mentally disabled in rehabilitation programs influenced improvement of self-care and also lessened a feeling of burden of families somewhat.

^13C-enriched Tunichrome Mm-2의 합성

백영숙 慶熙大學校 1992 論文集 Vol.21 No.-

^13C-enriched blood pigment of tunicate, Mm-2, was synthesized in which hydroxyl groups and amino group were protected with t-butyldimethylisilyl groups and t-butoxycarbonyl group, respectively. Vanillin-carbonyl-^13C was demethylated and the hydroxyl groups in the resulting 3,4-dihydroxybenzaldehyde-carbonyl-^13C were protected with t-butyldimethylsilyl chloride. Horner-Emmons Wittig reaction, in which bis-O-TBDMS-protocatechualdehyde-carbonyl-^13C was reacted with phosphonate in the presence of base, was employed to produce ^13C-enriched E-isomer as a major product. ^13C-enriched Z-isomer, the desired product, was obtained by photoisomerization of ^13C-enriched E-isomer using Rayonet RPR-3000 A˚fluorescent lamp.

유아기 그림 유우머 설명정도 및 감지정도와 창의성과의 관계

백영숙,손혜숙 경인여자대학 1997 경인논집 Vol.- No.6

The aim of this study is an attempt to understand children more effectively through the relationship between comprehension of pictorial humor and creativity in early childhood. Children's explanation of pictorial humor was analysed to ascertain : (1) the effect of age on the children's explanation of pictorial humor stimuli, (2) the effect of age on the children's appreciation of pictorial humor stimuli, (3) the rating of creativity on children's explanation of pictorial humor and (4) the rating of creativity on children's appreciation of pictorial humor. For this purpose, the explanation of pictorial humor and the appreciation of pictorial humor and integrated creativity were tested. Three major themes were used by Kang(1982). They consisted of themes such as taboo, aggression and sophistication. These themes were used in the current study to construct three pairs of drawings as humor stimuli. The children's explanations of pictorial humor were classified into four categories originally developed by Brown (1993). To measure creativity, the Integrated Creativity Test for four to six-year-old Korean Children developed by Chun (1995) was used. The subjects of this experiment were 90 four to six-year-old children who attended Kindergartens in Seoul and Pundang. The children were individually given the Humor Stimuli and Creativity Test. The analysis of data employed a oneway ANOVA and the Duncan test significance through SPSS/PC+. The results and conclusions of this study are as follows. 1) There were partly significant age differences in the rating of children's explanation of pictorial humor. That is, the six-year-old group showed higher explanation levels than the four-year-old and the five-year-old groups. 2)There were no significant age differences in the rating of children's appreciation of pictorial humor. That is, the higher old age group didn't show higher appreciation levels than lower old age groups. 3) There were significant differences in the explanation levels of pictorial humor in the rating of creativity. That is, the higher explanation levels of pictorial humor group ?? showed higher creativity scores than the lower explanation levels of pictorial humor group children. 4) There were no significant differences in the appreciation levels of pictorial humor in the rating of creativity. That is, the higher appreciation levels of pictorial humor group children didn't show higher creativity scores than the lower appreciation levels of pictorial humor group children. The above-mentioned findings were interpreted and discussed in terms of theoretical background and previous research findings. Some suggestions were presented for further study.

1,1-Diphenyl-2-methyl-1,2-propanediol의 산촉매 자리옮김

백영숙 慶熙大學校 1994 論文集 Vol.23 No.-

1,1-Diphenyl-2-methyl-1,2-propanediol 1 was synthesized to study the effect of solvents on the acid-catalyzed rearrangement reaction. Compound 1 was treated with concentrated sulfuric acid, acetic anhydride with trace amounts of sulfuric acid, trifluoroacetic acid, and various concentrations of trifluoroacetic acid/acetic acid. The products of compound 1 in these solvents system were examined by NMR spectra. The product ratios of 3,3-diphenylbutanone 2 and α,α-dimethylpropiophenone 3 were dramatically changed in different acidic media or even in different ratios of trifluoroacetic acid/acetic acid solution; the ratio of methyl migration to phenyl migration was 97:3 in trifluoroacetic acid and 59:41 in 30/70 trifluoroacetic acid/acetic acid. It was concluded that the effect of solvent is very important factor for the study of pinacol rearrangement.

한국 서남해안 두우리 조간대에서 표층 퇴적물 및 퇴적구조의 특성과 계절변화

백영숙,전승수,Baek Young Suk,Chun Seungsoo 한국석유지질학회 2004 한국석유지질학회지 Vol.10 No.1

한국 서남해안에 위치한 두우리 조간대는 사주와 보호섬이 존재하지 않고 외해로 열려있는 전형적인 개방형 조간대이다. 이러한 개방형 조간대에서는 바람에 의한 파랑이 퇴적작용에 중요한 요소의 하나이므로, 계절에 따른 파랑에너지의 차이가 조간대 표층퇴적물의 분포와 퇴적구조의 특성에 직접적으로 반영된다. 두우리 조간대는 상부의 조수해빈 (tidal beach), 중부의 전형적인 조간대 (intertidal flat)와 최하부의 니질대 (lowermost mudflat)로 구분된다. 이러한 구분은 표층퇴적물의 구성뿐만 아니라 조간대의 경사도에 의한 구분과도 일치한다. 조간대 내에서의 퇴적물은 1차 퇴적구조와 사서질 퇴적물의 함량에 따라 다시 사질 조간대, 혼합 조간대와 니질조간대로 나누어진다. 두우리 조간대의 표층퇴적상은 계절에 따라서 퇴적물의 함량과 퇴적구조에 변화를 보이며, 퇴적상의 변화양상은 계절풍의 방향과 세기, 폭풍과 밀접한 관련이 있다. 북서계절풍이 강한 겨울철과 봄철에는 사질 조간대의 퇴적상이 우세하며, 약한 남동풍이 우세한 여름철에는 니질 조간대의 퇴적상이 우세하게 분포한다. 가을철에는 혼합 조간대가 우세하게 나타난다. 표층퇴적물은 여름에는 전 조간대가 약 20 cm 두께의 니질 퇴적물로 뒤덮이고 가을이 지나 겨울로 가면서 니질 퇴적상에서 사질 퇴적상으로 바뀐다. 이러한 표층퇴적상의 변화는 바람도 세어지고 풍향도 바뀌어 조간대를 공격하는 파랑의 에너지가 강해지면서 여름철에 퇴적되었던 니질 퇴적물을 침식시키기 때문이다. 캔코아 주상시료에서 퇴적구조는 여름철에는 조간대 상부 ($0{\~}l.3 {\cal}km$)에서는 니질 퇴적물의 평행엽층리와 상승연흔 사엽층리가 하부 $(1.7{\~}2.3 {\cal}km)$에서는 괴상의 니질 퇴적층이, 겨울철에는 전체적으로 평행엽층리와 연흔사층리가 우세하게 나타나며, 부분적으로 둔덕사층리 (HCS)가 나타난다. The Doowoo-ri tidal flat in the southwestern Korean coast is a typical open-coast tidal flat which has no barriers in the offshore such as barrier island and sand bars. The difference of induced wave energy with seasons is affected directly on the distribution of surface sediment and the formation of sedimentary structures because the sedimentation by wind wave is relatively much important element in this open-coast tidal flat. This open-coast tidal flat can be classified into tidal beach, intertidal flat and lower mudflat according to the pattern of geomorphology and sediment type. The intertidal flat can be again divided into 3 types: sand flat, mixed flat and mud flat based on the primary sedimentary structure and sand/mud ratio. Doowoori tidal flat shows a seasonal change in the surface sedimentary facies based on sediment composition and primary sedimentary structure. The change is closely related to the direction and magnitude of monsoon wind and also to storm frequency. In winter and spring, when northwesterly wind is most dominant and strong and also storms are common, sand-flat facies is largely distributed on the intertidal flat, whereas mud-flat facies is most dominant during summer when weak southeasterly wind is common. In the fall season, mixed-flat facies is dominant on the flat. The Doowoori intertidal flat is covered by mud sediment which is ca. 20 cm in thickness in summer season. In winter season, surface sediment is changed from mud to sand because the summer mud is mostly eroded by strong wave action. Can-core peels in the intertidal flat show that parallel laminated mud or sand/mud and climbing ripple cross-laminated sandy silt are dominant on the upper intertidal flat $(0-1.3 {\cal}km)$ during summer season. On the other hand, on lower intertidal flat $(1.7-2.3 {\cal}km)$, dominant sedimentary facies is homogeneous mud. In winter, it is changed into parallel laminated and ripple cross-laminated sand facies.