흡연에 의한 급성 호산구성 폐렴 2예

박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.

영도구의 생식보건사업 성과분석 : 남자중학생을 대상으로 한 성교육 효과 분석을 중심으로 the Effects of Sex Education on Middle School Students

남은우,강혜숙,박성빈,최재임,민체류 고신대학교 영도발전연구소 2001 영도연구 Vol.3 No.-

The purpose of this study was to reduce the sexual problems of middle school students in Youngco-Gu, Busan. The survey was conducted by content analysis which was related with reproductive healty services such as budget, manpower, etc. This study was also conducted with sex education as the object and to measure the effects of sex education. Questionnaires from 203 students(7th-9th graders) in a male middle school were surveyed on Sept. 12-14, 2001. The statistical analysis used were t-test, paired t-test, one-way ANOVA and χ^2 test by using SPSS/PC+ WIN 8.0 program. The results of this study are summarized as follows: First, 66.2% of the students among the subjects had a religion, and of those 50% were buddhists, 34.4% christians, 9.5% catholic. Religion of sexual related matters showed no significant effect. Of these students 68.1% showed medium interest in sexual related matters, 18% little interest or none and 13.5% high interest. 8th graders seemed to show more interest in sexual related matters than other grades. 41.8% of Students seemed to get information on sexual matters from friends and 27.1% from the internet. 30.9% of the respondents talked about their boy/girl friends with their parents compared to 43.3% who chose to talk to their friends about their sexual related problems. Second, 56.7% logged into lascivious-sites on the internet. Of those who logged onto lascivious-sites 46.1% logged in once or twice a month, 31.9% once or twice a week, and 2.7% logged in daily, 69.2% Felt curiosity, 23.4% felt indecent and 7.5% felt like engaging in a sexual act after visiting one of these sites. Third, the effects of sex education on experimental groups of 7th graders showed a 2.1 point increase(p<0.1), 4 point increase for 8th graders(p<.001), and 9th graders increased by 3.3 points(p<.001). Therefore this showed that it was advantageous for students to have sex education. Fourth, the effects of sex education on the students attitude showed only a little more improvement than before in the controlled groups whereas the experimental groups showed a large increase in good attitude in a good direction. Therefore, the experimental groups showed better results in sexual attitude compared to the controlled groups(p<.01).

高果糖 誘導 고지혈증 흰쥐에 대한 薏苡仁의 효과

이영종,손영종,임덕빈,이은섭,박중수,김성기 대한본초학회 2005 大韓本草學會誌 Vol.20 No.1

Objective : In order to examine the effects of Coicis Semen on the hyperlipidemia, the extracts of Job's Tears were given to hyperlipidemic rats induced by fructose-rich chow. Method : The hyperlipidea was induced by fructose-rich chow during five weeks in rats. And the rats were administered with the extracts prepared from husk layer, bran layer, polished rice, unpolished rice or unhulled grain of Job's Tears each others during three weeks. And then, the effects of the extracts on body weight gain, total cholesterol, triglyceride and blood glucose were examined. Results and Conclusion : The extracts prepared from polished rice, unpolished rice or unhulled grain of Job's Tears had no effects on the body weight gains of the corpulent rats induced by a high fructose diet. Meanwhile, the extracts prepared from the unhulled grain (Coicis Semen), unpolished rice, and bran layer of Job's Tears decreased the levels of blood total cholesterol. and triglyceride, each others. And the effect of unhulled grain was more stronger than those of the others. The results suggested that unhulled grain had some materials useful for alleviating the hyperlipidemia, and the effective molecule is existed in the surface of unhulled grain.

무증상 당뇨환자의 T 반사 변화

안규환,조용진,김상화,사은희,임용빈,김대성,정대수,박규현 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

지리산국립공원 내 5개 습지구역의 식물상

안종빈 ( Jong Bin An ),박정근 ( Jeong Geun Park ),박삼봉 ( Sam Bong Park ),김봉규 ( Bong Gyu Kim ),박은희 ( Eun Hee Park ),추갑철 ( Gab Chul Choo ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

본 연구는 지리산국립공원 내에 위치한 5개 습지구역인 덕평봉, 세석, 왕등재, 외곡, 정령치의 식물상을 파악하여 습지구역의 보전 및 기초자료로 제공하고자 수행하였다. 현지조사는 2010년 3월부터 8월까지 실시하고, 2013년 6월부터 8월까지 보완조사를 실시하였다. 조사 결과 5개 습지구역에서 출현한 관속식물은 총 68과 175속 243종 5아종 29변종 277분류군이 조사되었다. 희귀식물은 CR등급(멸종위기종) 1종(방울난초), EN등급(위기종) 2종(분홍바늘꽃, 흰참꽃나무), VU등급(취약종) 3종(가문비 나무, 시호, 버들금불초), LC등급(약관심종) 9종(구상나무, 세잎종덩굴, 낙지다리 등), DD등급(자료부족종) 2종(물석송, 지리바꽃), 총 14과 17속 14종 3변종 17분류군이 조사되었다. 특산식물은 구상나무 등 8분류군이 나타났다. 식물구계학적 특정식물 Ⅴ등급은 2종, Ⅳ등급은 3종, Ⅲ등급은 6종, Ⅱ등급은 17종, Ⅰ등급은 15종이 각각 출현하여 총 25과 42속 42종 1변종 43분류군이 출현하였다. 귀화식물은 소리쟁이 1종이 정령치에서 출현하였다. This study was carried out to investigate flora distribution of 5 wet lands(Deokpyeong-bong, Seseok, Wangdeungjae, Oegok, Jeongnyeongchi) in Jirisan Korea National Park in order to establish efficient conservation and base line data of wet lands area. The field survey was conducted from March to August in 2010 and supplements investigate from June to August in 2013. The flora of 5 wet lands in Jirisan National Park were found to be; 277 taxa; 68 families, 175 genus, 243 species, 5 subspecies, 29 varieties. Rare plants were found to be; 14 taxa, 17 genus, 14 species, 3 varieties. Among them CR degree was found to be 1 species( Habenaria flagellifera), EN degree; 2 species( Epilobium angustifolium, Rhododendron tschonoskii), VU degree; 3 species( Picea jezoensis, Bupleurum falcatum, Inula salicina var. asiatica), LC degree; 9 species( Abies koreana, Clematis koreana, Penthorum chinense, Viola albida, Gentiana triflora var. japonica, Lilium distichum, Tricyrtis macropoda, Iris ensata var. spontanea, Acorus calamus), DD degree; 2 species( Lycopodium cernuum, Aconitum chiisanense). In all surveyed areas, a total of 8 species( Abies koreana, Filipendula formosa, Carex okamotoi etc.) were found to be endemic to Korea. Distribution of floristic special plants in the surveyed areas were found to be divided into five classes (class Ⅰ∼Ⅴ). The floristic special plants found in surveyed areas were 2 taxa of grade Ⅴ, 3 taxa of grade Ⅳ, 6 taxa of grade Ⅲ, 17 taxa of grade Ⅱ, 15 taxa of gradeⅠ. One species of naturalized plants ( Rumex crispus) was found in Jeongnyeongchi.

Evaluation of 40K Concentration in Samples Containing High Concentration of 232Th

Eun Ji Park,Sung Han Lee,Young Hwan Park,Su Bin Heo,Seong Gyu Lim,Dong Cheol Jang,Seung Beom Seo 한국방사성폐기물학회 2022 한국방사성폐기물학회 학술논문요약집 Vol.20 No.2

In 2018, media reports raised issues related to radon released from building materials used as finishing materials in apartment houses. Accordingly, related ministries recommended not to use materials with a radiation index value exceeding 1. In order to calculate the radioactivity index, not only 226Ra producing radon (222Rn) but also 232Th and 40K radioactivity concentrations are required. To determine the concentration of the radionuclide, 40K is measured by a single gamma ray of 1,460.8 keV. And the 228Ac used to measure 232Th mainly utilizes gamma rays of 911.2 keV. However, 228Ac does not appear as a single peak unlike 40K, and appears as multiple peaks at various energies. Among them, gamma rays are emitted at a intensity of 0.83% at 1,459.2 keV, which is likely to interfere with 40K. Therefore, what is actually measured at 1,460.8 keV is theoretically a compound peak of 40K and 228Ac. Because the probability of emission at 1,459.2 keV (0.83%) is low, a low concentration of 232Th will result in little 40K radioactivity error. However, samples containing a high concentration of 232Th overestimate the 40K radioactive concentration, so correction is required. In this study, the IAEA standard substance (IAEA-RGTh-1) ontaining 232Th of actual high concentration was analyzed, and the results of the analysis without correction of 40K were compared and verified. As the 40K correction method, the 911.2 keV gamma-ray of 228Ac was used as the reference peak to separate the peak of 228Ac (1,459.2 keV) from the 40K (1,460.8 keV) mixed peaks. And, the coefficient value obtained by subtracting the peak of 228Ac (1,459.2 keV) from the 40K (1,460.8 keV) mixed peak was set to a pure peak of 40K and the radioactivity concentration was calculated therefrom. As a result of calculating the IAEA-RGTh-1 reference material without correction, it was confirmed that the 40K value was overestimated by about 38 times. If a measurement beyond the MDA of 40K is generated by 228Ac radioactivity because the 40K correction constant is not applied, there is an error in determining that there is 40K radioactivity. However, even if 40K radioactivity is overestimated due to the high concentration of 232Th, the degree to which this effect contributes to the radioactivity index is very small. However, as an analyst, 40K radioactivity correction should be made for more accurate analysis.

Germination Characteristics and Seed Dormancy of Iris dichotoma Pall., an Endangered Species Native to Korea

Park, Hyeong Bin,Lee, Byoung-Doo,Lee, Chang Woo,Hwang, Jung Eun,Park, Hwan Joon,Kim, Seongjun,An, Jiae,Kim, Pyoung Beom,Kim, Nam Young National Institute of Ecology 2021 국립생태원회보(PNIE) Vol.2 No.4

Iris dichotoma Pall. found on Daechung Island in Korea has been designated as an endangered species. To aid in conservation efforts of this species, this study investigated its germination characteristics and seed dormancy type. Four sets of seeds were incubated at different temperatures (4/1℃, 15/6℃, 20/10℃, and 25/15℃). One set of seeds was cold stratified (4 weeks at 4/1℃). The final germination rate and mean germination time showed that the optimal germination temperature was 25/15℃. Final germination rates were ~70%, showing no significant difference among temperature treatments. However, mean germination time were significantly different among all temperature treatments except for 4/1℃. Mean germination time for seeds with temperature treatments of 15/6℃, 20/10℃, and 25/15℃ were 3.2, 2.1, and 1.5 weeks, respectively. At 25/15℃, the mean germination time was half of that at 15/6℃. Seeds of I. dichotoma had fully developed embryos at the time of dispersal. No additional growth of the embryo was observed. Cold stratification did not affect the final germination rate or the mean germination time. This study shows that seeds of I. dichotoma have no physiological or morphological dormancy, unlike other members of the Iris genus known to have seed dormancy that needs a relatively high incubation temperature (≥25/15℃) for mass propagation to occur. These results will be useful for understanding ecophysiological mechanisms related to the species' habitat. They are also useful for mass propagation of I. dichotoma for the purpose of conserving this endangered species.

Investigation of the Potential of Modified Handmade Cloning (mHMC) Assisted with Demecolcine (DEM) in Porcine Embryo Cloning

Eun Ji Lee,Kuk Bin Ji,Kang Sun Park,Kyeong Yeob Kim,Beom Sik Kim,Kyu hyun Kim,Ryeong Eun Kim,Eun Young Kim,Ji Hye Lee,Ju Lan Chun,Min Kyu Kim 한국동물생명공학회(구 한국동물번식학회) 2018 발생공학 국제심포지엄 및 학술대회 Vol.2018 No.06

Somatic cell nuclear transfer(SCNT) using micromanipulator have been used as a traditional cloning technique and applied various researches during the last decades. However the micromanipulator is expensive and relatively longer training period is required to operate it efficiently. Handmade cloning(HMC) is an alternative cloning method in a simplified way compared to the traditional cloning. Here, we suggested modified porcine handmade cloning(mHMC) as a new approach to clone porcine embryos as a substitute of the traditional SCNT. In mHMC, a nucleus was removed by an aspiration method by using a glass pipette, instead of bisection method. In this study, we investigated the efficiency of the enucleation method in mHMC by assessing the developmental competence of embryos in comparison with the traditional SCNT. The efficiency of enucleation was evaluated based on the rate of the accuracy and oocyte survivability. The accuracy of enucleation was lower in mHMC compared to those in SCNT(98.01±0.57 vs. 83.83±2.47), and the rate of survived oocytes was also lower in mHMC(96.50±0.84 vs. 90.10±2.11, respectively). And the developmental competence was assessed. The blastocyst rate was significantly higher in mHMC group(13.53±2.08 vs. 20.48±0.99). The levels of apoptosis and ROS were investigated to evaluate embryo quality. The expression of ROS and apoptosis-related genes showed no difference between groups. And the relative expressions of mRNA of pluripotency genes and reprogramming genes were evaluated. Although DNMT1 and DNMT3α were not differently expressed in two groups, the expression of the one of pluripotent gene, Oct4 was significantly higher in mHMC. In conclusion, based on the comparable results of mMHC and SCNT, the mHMC could be a suitable alternative technique to clone embryos in cost effective way compared to traditional SCNT.

Effects of GSICS correction on estimation of sea surface temperature using COMS data

Park, Eun-Bin,Han, Kyung-Soo,Yeom, Jong-Min,Lee, Chang-Suk,Ryu, Jae-Hyun,Kim, Hyunji,Kim, Do-Hyeong Informa UK (TaylorFrancis) 2015 International journal of remote sensing Vol.36 No.4

Perioperative Respiratory-Adverse Events Following General Anesthesia Among Pediatric Patients After COVID-19

Park Jung-Bin,Sohn Jin Young,Kang Pyoyoon,Ji Sang-Hwan,Kim Eun-Hee,Lee Ji-Hyun,Kim Jin-Tae,Kim Hee-Soo,Jang Young-Eun 대한의학회 2023 Journal of Korean medical science Vol.38 No.47

Background: The perianesthetic morbidity, mortality risk and anesthesia-associated risk after preoperative coronavirus disease 2019 (COVID-19) omicron variant in pediatric patients have not been fully demonstrated. We examined the association between preoperative COVID-19 omicron diagnosis and the incidence of overall perioperative adverse events in pediatric patients who received general anesthesia. Methods: This retrospective study included patients aged < 18 years who received general anesthesia between February 1 and June 10, 2022, in a single tertiary pediatric hospital. They were divided into two groups; patients in a COVID-19 group were matched to patients in a non-COVID-19 group during the omicron-predominant period in Korea. Data on patient characteristics, anesthesia records, post-anesthesia records, COVID-19-related history, symptoms, and mortality were collected. The primary outcomes were the overall perioperative adverse events, including perioperative respiratory adverse events (PRAEs), escalation of care, and mortality. Results: In total, 992 patients were included in the data analysis (n = 496, COVID-19; n = 496, non-COVID-19) after matching. The overall incidence of perioperative adverse events was significantly higher in the COVID-19 group than in the non-COVID-19 group (odds ratio [OR], 1.92; 95% confidence interval [CI], 1.89–1.94). The difference was significant for PRAEs (OR, 2.00; 95% CI, 1.96–2.02) but not in escalation of care or mortality. The most pronounced difference between the two groups was observed in instances of high peak inspiratory pressure ≥ 25 cmH2O during the intraoperative period (OR, 11.0; 95% CI, 10.5–11.4). Compared with the non-COVID-19 group, the risk of overall perioperative adverse events was higher in the COVID-19 group diagnosed 0–2 weeks before anesthesia (OR, 6.5; 95% CI, 2.1–20.4) or symptomatic on the anesthesia day (OR, 6.4; 95% CI, 3.30–12.4). Conclusion: Pediatric patients with the preoperative COVID-19 omicron variant had increased risk of PRAEs. Patients within 2 weeks after COVID-19 or those with symptoms had a higher risk of PRAEs.