Baclofen 投與에 따른 精神分裂症 患者의 血淸 成長호르몬의 反應

李圭煥,白仁浩,高孝進,李正杓,咸雄,李奎恒 서울醫大 1990 精神醫學 Vol.15 No.1

Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

논문 : 동북아지역(東北亞地域)에서의 다뉴경(多뉴鏡) 부장묘(副葬墓)의 전개(展開)

이청규 ( Chung Kyu Lee ) 단국사학회 2012 史學志 Vol.44 No.-

청동기는 생업도구의 수준에서 벗어나 전쟁무기와 종교의기로 제작·보급되었다. 이논문은 종교의기이자 무구(巫具)로서 제사장들이 보유했던 청동거울, 그 가운데서도 다뉴경을 중심으로 다뉴경이 부장된 무덤들의 역사문화적 의미를 고찰한다. 다뉴경은 대릉하유역부터 한반도를 거쳐 일본 구주(九州)지역에 이르는 범(汎) 십이대영 자문화권(十二臺營子文化圈)을 나타내는 유물이다. 다뉴경 부장묘는 이 문화권에 속한 고조선, 부여, 한 왜(倭)의 범주에 속하는 소국(小國)들의 수장들의 무덤으로서, 다뉴경뿐만 아니라 다른 청동기 및 토기부장품들이 부장되어 있다. 이 부장품들은 당시의 chiefdom 사회의 수장들을 중심으로 한 정치상황뿐만 아니라 범 대영자문화권 내의 기술교류를 반영한다. 다뉴경은 중국 동북지역에서 한반도와 일본열도에 걸쳐 당시 엘리트들이 제사장의 신분과 지위를 과시하는 위세품인데, 전파과정에 따라 대릉하지역의 A형 다뉴경, 요동과 길림지역의 B형 다뉴경, 한반도 서남부와 일본 구주지역의 C형 다뉴경으로 발전되어갔다. A형 다뉴경으로부터 B형 다뉴경의 등장은 연(燕)나라의 동진으로 고조선의 강역이 이동한 것에 기인한다. C형 다뉴경은 중국 동북지역에서는 발견되지 않고 한반도 서북한과 서남한 지역, 일본 구주(九州)지역에서 발견된다. 이는 다뉴경을 최고 위세품으로 채용하는 계층이 상위급 수장(首長)에서 차상급 이하의 엘리트로 내려갔음과 일본 구주 지역의 소국들이 한반도 서남부지역의 마한(馬韓)지역과 교류하고 있었음을 보여준다. The geometric-design bronze mirrors of which numbers about 80, are assumed to be as ritual tools and political symbols of priest-king during the 8th~2nd century BCE. Those are classified into three types, that are A, B, and C, and each of them is assumed to be made and used in 800~400BCE, 400~200BCE, and 200~50BCE. The distributional range of three types were changed under the historical conditions, which includes Yen(燕)`s advance toward the northeastern China and Wiman(衛滿) becoming a king of Gojoseon(古朝鮮). The first A type mirrors were distributed mainly in northeastern China, B type ones in the geographical range from northeastern China to the Korean peninsular, and C type ones from the Korean peninsular to the Japanese archipelago. The size and numbers of mirrors are reflective of the social position of the person with whom are buried in the grave, and so the graves with mirrors in each type are those of the most unfluential leaders of ``Kuk(國)``―the political and regional groups at the time. In A type mirror stage, the graves with most abundant artefacts are located in Liaoning pronince(遼寧省); the graves with most abundant artefacts in B type mirror stage are in Chung-nam(忠南) province; and the graves with C type mirrors in Cheon-nam(全南) province. Each region with those burials was the trade-center in Korea connecting China and Japan, and is assumed to be the location of the most influential ``Kuk(國)`` in old Korea.

Infliximab으로 호전된 장관 증상없이 발생한 구강-안면 크론병

정보용 ( Bo Yong Jung ),이석호 ( Suck Ho Lee ),정승규 ( Seung Kyu Chung ),이창균 ( Chang Kyun Lee1 ),이태훈 ( Tae Hoon Lee ),정일권 ( Il Kwun Chung ),김선주 ( Sun Joo Kim ),조현득 ( Hyun Deuk Cho ) 대한소화기학회 2012 대한소화기학회지 Vol.59 No.6

Crohn`s disease is a chronic inflammatory bowel disease that can involve the whole gastrointestinal tract. The orofacial manifestation of Crohn`s disease, which is rare, can develop irrespective of intestinal involvement. These orofacial lesions are often misdiagnosed as simple oral ulcers. Corticosteroids are the mainstay of therapy for orofacial Crohn`s disease. However, infliximab, the chimeric monoclonal antibody to tumor necrosis factor-α, is now considered as a primary treatment because of the disease`s relatively high rate of steroid resistance. We present a case of deep oral ulcer and periorbital swelling in a 65-year-old woman. She was diagnosed with intestinal Crohn`s disease 7 years ago, which was in remission after treatment with an immunosuppressive agent (azathioprine). The patient was given the diagnosed with orofacial Crohn`s disease and successfully treated with infliximab. (Korean J Gastroenterol 2012;59:437-440)

2個의 偏心圓孔을 갖는 帶板이 引張荷重을 받는 경우의 應力集中係數에 關한 硏究

丁太權,李圭泰 조선대학교 동력자원연구소 1984 動力資源硏究所誌 Vol.6 No.1

In designing the machine elements, the stress distribution of the material is so important that in this study it was examined by the photeelastic experiment using the double refraction properties. The width of the plate was 25㎜ and the diameter of the hole was fixed 5㎜ and the each center of the hole was eccentricified 0㎜, 2v, 4㎜, and 6㎜. In this condition, the plate with the two eccentric holes that the each distance of the holes were changed 5㎜, 8㎜ and 12㎜ was tensiled. The stress distribution near the holes of the free boundary was as follows : (1) The stress concentration factors were constant regardless of the distance of the centers of the holes. (2) The stress concentration factors were increased with the eccentric rate. (3) The maximum poimt of the stress concentration was moved toward opposite direction of the other holes. (4) Zero point was increased from the center line of the holes.

티타늄 임플랜트의 표면 마무리 상태 및 NaOH 수용액 침적이 유사체액 중에서의 인산칼슘 석출에 미치는 영향

정회웅,최규형,이민호,배태성 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.3

The purpose of this study was to examine whether the precipitation of calcium phosphate on titanium implant are affected by surface modification. To improve the bone conductivity of the Cheil implant(Cheil Pharma & Instrument Inc), samples were divided into 3 groups. Group 1 was untreated, group 2 was immersed in 5M-NaOH solution at 60℃ for 24 hours, and group 3 was immersed in 5M-NaOH solution at 60℃ for 24 hours and heat-treated at 600℃ for 1 hour. And then, all specimens were immersed in the MEM Eagle's medium whose composition was similar to that of extracellular fluid for 30 days. After immersion, the surfaces were observed with scanning electron microscope. The results obtained were summarized as follows; 1. The surface of Branemark implant showed more regular and smooth machined surface than that of Cheil implant. 2. The precipitation of the calcium phosphate on implant surface was increased by the immersion in the NaOH solution, and more highly accelerated by heat treatment. 3. The precipitation of the calcium phosphate on titanium implant was lower than that on the polished titanium surface.

三姓神話에 대한 고고학적 접근

李淸圭 제주대학교 탐라문화연구소 1994 탐라문화 Vol.0 No.14

Elastic Open Activator를 이용한 Ⅱ급 부정 교합의 치료효과

정규림,박영국,이현경 대한치과교정학회 1995 대한치과교정학회지 Vol.25 No.5

Elastic Open Activator(E.O.A)는 myodynamic activator의 일종으로서 장치의 아크릴 부위의 대폭적인 크기 감소로 환자가 거부감 없이 장시간 착용할 수 있는 장점을 가지며, 구강내에서 매우 느슨하게 장착되므로써 보다 적극적인 근기능 자극 효과를 나타내고, 구강 내외의 제 기능시 발휘되는 생리적인 힘을 효율적으로 치조골 및 악관절부에 전달시킨다. 특히 기능모체(functional matrix)를 효과적으로 차단하는 동시에 능동적으로 자극함으로써 많은 부정교함 증례에서 비발치에 의한 교정치료의 성공률을 높이는 것으로 사료된다. 이 연구는 혼합치열기 및 초기 영구치열기의 Ⅱ급 부정교합 환자에게 사용된 E.O.A의 치료효과를 구명하기 위하여 시행되었으며 경희의료원 교정과에 내원하여 Ⅱ급 1류 및 2류 부정교합으로 진단되었던 각각 9명과 5명의 치료 전후 cephalogram 및 석고모형을 비교분석한 후 결과를 평가하여 다음과 같은 결론을 얻었다. 1. 상악골은 두 군 모두에서 정상적인 성장 양태를 유지하였다. 2. 하악골은 두 군 모두에서 크게 전하방 성장되었다. 3. 상악 전치는 Ⅱ급 1류 부정교합자에서는 설측, Ⅱ급 2류 부정교합자에서는 순측 경사되었고 두 군 모두에서 상하악 전치부 치조골 수직 성장이 억제되었다. 4. 하악 전치는 두 군 모두에서 약간 순측 경사되었다. 5. 두 군 모두에서 상, 하악 치궁의 확장이 일어났으며 Ⅱ급 2류 부정교합자에서 가용 공극의 길이가 증가되었다. The elastic open activator is one of the modified myodynamic activator. The reduced size of the appliance mass motivates the patients' comfort and longer time of wearing. Its peculiarities in loose fitting and the lack of appliance stabilization in the mouth draws the tongue and the surrounding functional matrices on close interaction with the appliance, consigns the physiologic exertion to target structures, and eventually makes it feasible to the inland of non-extraction treatment. In the context of the sagittal malocclusion, the orthodontic trench is dependent upon the growth of basal structure aimed, therefore, it is contemplated to grabble the effects of Elastic Open Activator upon the class Ⅱ malocclusion of growing child retrospectively. The cephalometric headfilms and study models of nine class Ⅱ malocclusion of growing child retrospectively. The cephalometric headfilms and study models of class Ⅱ division 1 and five division 2 patients were evaluated and analyzed, and the following observations were drawn ; 1. The maxilla maintained a normal growth pattern in both groups. 2. The mandible grew anteroinferiorly in both groups. 3. The upper incisors tipped ligually in Class Ⅱ division 1 and tipped labially in Class Ⅱ division 2 and anterior vertical alveolar growth was interrupted in both groups. 4. The lower incisors tipped labially. 5. There was an arch expansion in both groups and increase of available space in Class Ⅱ division 2

척추수술환자에서 급성 동량성 혈액희석 및 유도저혈압을 병용한 마취관리

이규탁,민진혜,정창우 관동대학교 의과학연구소 2000 關東醫大學術誌 Vol.4 No.1

Due to the discovery that blood transfusion can evoked several side effects, there has been increased interest in technologies that reduce the amount of homologous blood used during and after surgery. Acute normovolemic hemodilution is known as a convinient and effective blood conservation method, and drug-induced hypotension can reduce the amount of intraoperative bleeding with better operative field. Combination of these two techniques was suggested to reduce homologous blood requirements in various surgeries. Therefore, to minimize homologous blood transfusion, we conducted general anesthesia using acute normovolemic hemodilution combined with induced hypotension in patient undergoing spinal fusion surgery. We think that the routine careful combination of these techniques can be carried out safely in many surgeries.

흰쥐 정소 간질세포의 발생에 관한 형태학적 연구

이법이,백태경,정호삼,이규식,박준영 한양대학교 의과대학 1993 한양의대 학술지 Vol.13 No.1

It is well known that interstitial cell of Leydig is developed from the mesenchymal cell in the intestitial tissue of the testis during fetal period, but it gradually regressed until puberty when mature Leydig cell is derived from the mesenchyme of interstitial tissue of fetal Leydig cell. The function of the Leydig cell is synthesis and secretion of testosterone which influences on differentiation of male geritalia at fetal period, and revealation of male secondary sexual characteristies and differentiation of sperm at puberty. To investigate the differentiation of interstitial cell in interstitium and ultrastructural changes of interstitial cell in rat testis and ultrastructural changes of interstitial cell in rat testis and relation to testosterone secretion, the author has studied this experiment. Fetal rats on the 16th, 18th and 20th gestational days and rats on the 1st, 3rd, 7th day, 2nd, 3rd and 8th week after birth were used as experimental animals. Some of obtained testis were stained with hematoxylin and eosin for light microscopic study, and other specimens were double stained with uranyl acetate and lead citrate for electron microscopic study. The results were as follows: 1. On the 16th day of pregnancy, a few of round eosinophilic Leydig cells are firstly observed in the interstitium of testis in fetal rat. On the 18th and 20th day of pregnance, 1st and 3rd day of neonatal life, a number of Leydig cells forming cellular cord were observed. On the 1st and 2nd week after birth, number and size of Leydig cell are markedly reduced but on teh 3rd week after birth Leydig cells are reappeared. On the 8th week after birth distribution of Leydig cells is similar to that in adult rat testis. 2. On the 18th and 20th day pregnancy, and 1st and 3rd day of neonatal life, circular or oval shaped mitochondria matrix were observed in the Leydig cell. On the 1st and 2nd week after birth, giant mitochondria and mitochondria with disorganized mitochondrial crista were revealed. On the 3rd and 8th week after birth, appearances of mitochondria were similar to that in Leydig cell of the rat testis on the 20th day of pregnancy. 3. Numerous and round cisternae of smooth endoplasmic reticulum were observed in Leydig cell of rat testis on the 18th and 20th day of pregnancy. 1st and 3rd day of neonatal life, and 1st week after birth . Horseshoe-shaped deformity and reduction in number of cisternae of smooth endopalmic reticulum were revealed in Leydig cells on the 2nd week after birth. Numerous and round cisternae of smooth endoplasmic reticulum were seen on the 3rd and 8th week after birth. 4. A few lipid droplets were revealed in Leydig cell of rat testis on the 18th day of pregnancy, but many lipid droplets were observed in Leydig cells of rat testis on the 20th day of gestation, 1st and 3rd day of neonatal life, and 1st week after birth. Numbers of lipid droplets were gradually decreased after 2nd week of postnatal life. 5. Many autophagic vacuoles were observed in Leydig cells would be firstly differentiated from the mesenchymeal cells in interstitium of fetal rat testis on the 16th day of pregnancy, and proliferated from the 18th day of pregnancy to the 1st day of neonatal life, and then gradually regressed before the puberty, but at the begining of puberty adult type of Leydig cell be proliferated.