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Bae, Sang-Cheol,Kim, Jinseok,Choe, Jung-Yoon,Park, Won,Lee, Sang-Heon,Park, Yong-Beom,Shim, Seung-Cheol,Lee, Shin-Seok,Sung, Yoon-Kyoung,Choi, Chan-Bum,Lee, So-Ra,Park, HanYu,Ahn, Yongho H. K. Lewis 2017 Annals of the rheumatic diseases Vol.76 No.1
<P>Conclusion The study met the primary objective of demonstrating equivalent efficacy of HD203 and ETN. HD203 was well tolerated, with safety comparable with ETN in this population of patients with RA.</P>
Shim, Jae-Hyun,Yoon, Seok-Mann,Shim, Jai-Joon,Kim, Ra-Sun The Korean Neurosurgical Society 2011 Journal of Korean neurosurgical society Vol.50 No.3
Intracranial dural arteriovenous fistulas (DAVFs) are abnormal arteriovenous connections that lie within the dura. Intraosseous DAVFs involving diploic venous system are extremely rare. A 46-year-old woman presented with headache and right pulsatile tinnitus for three weeks. The tinnitus started after yelling. Digital subtraction angiography revealed DAVF within the basal portion of right parietal bone along the middle meningeal artery (MMA) groove. The fistula was fed by frontal branch of right MMA and drained into right transverse sigmoid sinus junction through dilated middle meningeal vein. The intraosseous DAVF involving diploic vein was successfully obliterated with Onyx embolization via transarterial route.
( Na Ra Shim ),( Eun Jin Bae ),( Ji In Park ),( Sun Hwa Lee ),( Ha Jeong Lee ),( Dong Ki Kim ),( Yong Lim Kim ),( Shin Wook Kang ),( Chul Woo Yang ),( Yon Su Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Malnutrition is a common and crucial problem because it is associated with higher mortality in chronic dialysis patients. Subjective global assessment (SGA) has been proven as a clinically adequate method for assessing nutritional status in dialysis patients. We explored the relationships between initial and transitions of SGA and all-cause mortality. Methods: A nation-wide prospective observational cohort study included adult chronic dialysis patients. We selected patients who had baseline and 12 month follow-up SGA. SGA-7 score was categorized as well-nourished (SGA 6~7) and malnourished (SGA 1~5) groups. The changes of SGA were categorized by 4 groups (well-maintained, poorly-maintained, improving, and worsening group). Results: A total of 2,600 patients were selected and mean age was 55.7±14 years old and 57.2% of patients were male. The mean follow-up period was 28.5 months. During the follow-up period, 202 patients (7.8%) were died. The mortality rate in malnourished patients was higher in both incident (5.2% vs. 13%, p<0.001) and prevalent patients (6.3% vs. 20.4%, p<0.001). The survival rate was signifi cantly higher in well-nourished patients in 12 month follow-up (p<0.001). Moreover, in terms of SGA transition, improving and well-maintained groups had better survival rate than worsening group and poor-maintained group. These fi ndings were reproducible even afteradjustment of age, gender, smoking, BMI, comorbidity, serum albumin, cholesterol and hs-CRP (HR 2.913, 95% CI, 1.856-4.573, p<0.001). Conclusions: Malnutrition assessed by SGA was an independent predictor for allcause mortality. Furthermore, the transition of SGA was also correlated with mortality in chronic dialysis patients.
Case Report : A case of Embryonal Rhabdomyosarcoma Of the Uterine Cervix in a Middle-Aged Woman
( A Ra Shim ),( Ma Ria Lee ),( Ji Heum Paek ),( Min Ju Kim ),( Sang Wun Kim ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.11
Embryonal rhabdomyosarcoma (RMS) of the cervix is rare and most commonly occurs in the late teens and early 20s. We report a case of cervical embryonal RMS in a 52-year-old woman. This patient presented with an abnormal vaginal bleeding for 2 months and a mass protruding from the introitus, measuring 7 × 6 cm. She underwent radical abdominal hysterectomy with bilateral pelvic lymph node dissection and radical vaginectomy. The fi nal pathologic result was cervical RMS, consistent with the Intergroup RMS study group IIC. Immunohistochemistry was positive for desmin, myogenin, and myogenic diffentiation 1. The patient received conservative management in a convalescent hospital without adjuvant treatment due to cerebral hemorrhage and relapsed septic condition after surgery.
( A Ra Shim ),( Yu Im Hwang ),( Kyung Jin Lim ),( Young Mi Choi ),( Young Eun Jeon ),( Seok Kyo Seo ),( Si Hyun Cho ),( Young Sik Choi ),( Byung Seok Lee ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.11
Objective To evaluate the clinical, hormonal and metabolic characteristics according to luteinizing hormone (LH)/follicle stimulating hormone (FSH) ratio in women with polycystic ovary syndrome (PCOS). Methods A total of 225 women with PCOS were included in this study. They were divided into two groups according to LH/FSH ratio; group A (LH/FSH < 2, n=160) and group B (LH/FSH > 2, n=65). We compared clinical, hormonal and metabolic characteristics including age at menarche, body mass index (BMI), blood pressures, ovarian volume, and serum androgen levels between the two groups. Serum glucose and insulin levels, fasting glucose/insulin ratio, homeostatic model assessment of insulin resistance (HOMA-IR), and lipid profi les were also compared between the two groups. Pearson correlation coeffi cients were used to evaluate correlation between the LH/FSH ratio and various parameters. Results Age of menarche in the group B was signifi cantly later than that in the group A. BMI, waist-hip ratio and blood pressures were signifi cantly lower in the group B compared to those of the group A. Ovarian volume and serum levels of LH, estradiol, total testosterone, sex-hormone binding globulin, 17-hydroxyprogesterone (OHP), and high density lipoprotein were signifi cantly higher in the group B. Postprandial 2 hours glucose, insulin and HOMA-IR were signifi cantly higher in the group A. After adjustment of BMI, the LH/FSH ratio was signifi cantly positively correlated with age at menarche, ovarian volume, total testosterone levels, and 17-OHP levels. Conclusion The inappropriate gonadotropin secretion may be negatively correlated with BMI, and positively with age of menarche and increased ovarian androgen production irrespective of BMI in women with PCOS. However, it may not be associated with metabolic characteristics.
조직정치 지각이 조직구성원들의 반생산적과업활동에 미치는 영향 : 기업의 사회적 책임활동 정당성 인식의 매개효과, 고용불안정의 조절효과
심미라 ( Mi-Ra Shim ),조윤형 ( Yoon-Hyung Cho ) 한국생산성학회 2021 生産性論集 Vol.35 No.3
Counterproductive work behaviors(CWB) are behaviors by employees intended to harm their organization or organization members, such as theft, sabotage, interpersonal aggression, work slowdowns, wasting time and/or materials, and spreading rumors. This research CWB are conceptualized workplace deviance as voluntary behavior that violates significant organizational norms and in so doing threatens the well-being of an organization, its members, or both(Bennett & Robinson, 2000; Robinson & Bennett, 1995). CWB are consist of types of deviance was whether the deviance was directed or targeted at either the organization(organizational deviance) or at members of the organization (interpersonal deviance) and its associated organizational costs necessitates a specific, systematic, theoretically focused program of study into this behavior. This research investigate to critical antecedents of CWB such as perception of organizational politics(POP). Also perceived corporate social responsibility(CSR) legitimacy mediated between POP and CWB. Finally, we checked job insecurity moderate between POP and CSR legitimacy and verify the moderated mediation effect. POP defined perceived behavior of proves beneficial or harmful to the organization may depend more on how that behavior is perceived rather than reality. The management of influence to obtain ends not sanctioned by the organization or to obtain sanctioned ends through non-sanctioned influence which divided into go along to get ahead and pay/promotion policies. Based on the literature review, we set the direct effect, mediated effect, moderate effect, and moderated mediation effect of hypotheses. To test whole of hypotheses, total of 315 questionnaires are used for analysis. To protect the common method bias, 2<sup>nd</sup> times collecting the questionnaires with time lag of three months. The samples are focus on the CSR activities of 15 companies at Gwanju and Choennam area. The results of empirical test conducted process macro(Hayes, 2018) are as follows. First, POP: pay/promotion policies increased both of interpersonal and organizational CWB. Second, POP: pay/promotion policies decreased perceived CSR legitimacy. Third, job insecurity increased both of interpersonal and organizational CWB however decreased perceived CSR legitimacy. Third, perceived CSR legitimacy mediated between POP: pay/promotion policies and both of interpersonal and organizational CWB. Fourth, job insecurity moderate between POP: pay/promotion policies and perceived CSR legitimacy. Finally, conditionally indirect effect reflected moderation of job insecurity and mediation of perceived CSR legitimacy which POP: pay/promotion policies and both of interpersonal and organizational CWB relationship. Based on the result, we found that POP: pay/promotion policies, job insecurity are determinants of both of interpersonal and organizational CWB. It was found that if an employee perceives the work environment to be political, he or she reports greater levels of CWB, and lower levels of CSR legitimacy. So that means organization use political manipulations of performance pay and promotion appraisal systems to reward favored employees, send messages to employees who have fallen out of favor, and to build paper trails justifying expected terminations and should attempt to reduce politics in the work environment, as employees’ perceptions of such activities lead to CWB. Moreover, perceived CSR legitimacy conducted mediating role of those of relationship and moderating role of job insecurity. If high on job insecurity, POP: pay/promotion policies negative impacts on boost up perceived CSR legitimacy. This results show that if company dedicate CSR activities, they must build up the alignment of mission, vision, value for legitimacy and mitigate of political behavior in the organizations. Also organizations have been downsizing for competitive advantage caused employee feelings of unstable and violating psychological contract concerning the nature and continued existence of their jobs. The efforts of diminish job insecurity thus become important undertakings. it may be that organizations might be able to take steps to prevent job insecurity from occurring CSR legitimacy and CWB.
성경험이 없는 36세 여성 자궁경부에서 발생한 편평세포암
심아라 ( A Ra Shim ),최은경 ( Eun Kyoung Choi ),윤성현 ( Sung Hyun Yun ),이마리아 ( Ma Ri A Lee ),이미경 ( Mi Kyung Lee ),김상운 ( Sang Wun Kim ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.10
The carcinoma of the uterine cervix in virgins is extremely rare. A 36-year-old virgin presented with a 4.8 × 2.2 cm sized endocervical mass with bleeding on sonography. Biopsy revealed a squamous cell carcinoma arising in the uterine cervix without human papilloma virus (HPV) DNA. Positron emission tomography revealed cervical cancer with multiple hematogenous lung metastases. After 3 cycles of preoperative chemotherapy, she underwent modified radical hysterectomy and 6 cycles of postoperative chemotherapy. After the treatment, complete resolution was obtained, and she has been followed without recurrence for 4 years. Although > 90% of cervical cancer is caused by HPV infection, we cannot completely deny the possibility of HPV negative cervical carcinoma.
Rhodamine 6G 용매에 따른 CA 훈증 지문 증강 효과에 관한 연구
심예라(Yea-Ra Shim),유제설(Je-Seol Yu) 한국콘텐츠학회 2017 한국콘텐츠학회논문지 Vol.17 No.7
본 연구에서는 잠재지문이 유류되어 있는 비다공성 또는 반다공성 검체를 CA 훈증하여 지문을 현출한 후 현출된 지문을 증강하기 위해 Rhodamine 6G를 사용하였다. 각기 다른 용매를 기반으로 조제한 두 종류의 Rhodamine 6G 용액 중 어떤 것이 더욱 효과적으로 지문을 증강할 수 있는지 알아보고자 하였다. 실험에 사용한 일곱 종류의 표면 모두 유기용매 기반 Rhodamine 6G보다 수용성 기반 Rhodamine 6G를 사용하였을 때 지문이 잘 증강되고 배경 염색도 적었다. 그러나 실제 현장에서 수집되는 감식 대상은 다양한 표면 재질과 색상을 가지는 한계점이 있으므로 이를 바탕으로 추후 연구가 필요할 것으로 사료된다. In this study, latent fingermarks deposited in porous or non-porous surface was developed by cyanoacrylate fuming, and then the developed fingermark is enhanced by using Rhodamine 6G. Between water-based R6G and organic solvent-based R6G, author studied about which material have higher effectiveness in enhancing fingermark. In all seven types of surfaces depositing fingermark, water-based R6G have higher effectiveness in enhancing fingermark and lower surface coloring than organic solvent-based R6G. But because the surfaces found in crime scene have multicolor background and various quality, the additional study about various surfaces is needed.