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성경험이 없는 36세 여성 자궁경부에서 발생한 편평세포암
심아라 ( A Ra Shim ),최은경 ( Eun Kyoung Choi ),윤성현 ( Sung Hyun Yun ),이마리아 ( Ma Ri A Lee ),이미경 ( Mi Kyung Lee ),김상운 ( Sang Wun Kim ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.10
The carcinoma of the uterine cervix in virgins is extremely rare. A 36-year-old virgin presented with a 4.8 × 2.2 cm sized endocervical mass with bleeding on sonography. Biopsy revealed a squamous cell carcinoma arising in the uterine cervix without human papilloma virus (HPV) DNA. Positron emission tomography revealed cervical cancer with multiple hematogenous lung metastases. After 3 cycles of preoperative chemotherapy, she underwent modified radical hysterectomy and 6 cycles of postoperative chemotherapy. After the treatment, complete resolution was obtained, and she has been followed without recurrence for 4 years. Although > 90% of cervical cancer is caused by HPV infection, we cannot completely deny the possibility of HPV negative cervical carcinoma.