Copolymerization of Ethylene and Norbornene via Polymethylene Bridged Dinuclear Constrained Geometry Catalysts

Zhu, Yin-Bang,Jeong, Eung-Yeong,Lee, Bae-Wook,Kim, Bong-Shik,Noh, Seok-Kyun,Lyoo, Won-Seok,Lee, Dong-Ho,Kim, Yong-Man The Polymer Society of Korea 2007 Macromolecular Research Vol.15 No.5

The dinuclear half-sandwich CGCs (constrained geometry catalyst) with a polymethylene bridge, $[Ti({\eta}^5 : {\eta}^1-indenyl)SiMe_2NCMe_3]_2(CH_2)_n]$[n = 6 (1) and 12 (2)], have been employed in the copolymerization of ethylene and norbornene (NBE). To compare the mononuclear metallocene catalysts; $Ti({\eta}^5 : {\eta}^1-2-hexylindenyl)SiMe_2NCMe_3$ (3), $(Cp^* SiMe_2NCMe_3)$Ti (Dow CGC) (4) and ansa-$Et(Ind)_2ZrCI_2$ (5), were also studied for the copolymerization of ethylene and NBE. It was found that the activity increased in the order: 1 < 2 < 3 < 5 < 4, indicating that the presence of the bridge between two the CGC units contributed to depressing the polymerization activity of the CGCs. This result strongly suggests that the implication of steric disturbance due to the presence of the bridge may playa significant role in slowing the activity. Dinuclear CGCs have been found to be very efficient for the incorporation of NBE onto the polyethylene backbone. The NBE contents in the copolymers formed ranged from 10 to 42%, depending on the polymerization conditions. Strong chemical shifts were observed at ${\delta}$42.0 and 47.8 of the isotactic alternating NBE sequences, NENEN, in the copolymers with high NBE contents. In addition, a resonance at 47.1 ppm for the sequences of the isolated NBE, EENEE, was observed in the $^{13}C-NMR$ spectra of the copolymers with low NBE contents. The absence of signals for isotactic dyad at 48.1 and 49.1 ppm illustrated there were no isotactic or microblock (NBE-NBE) sequences in the copolymers. This result indicated that the dinuclear CGCs were effective for making randomly distributed ethylene-NBE copolymers.

Iridoid Compounds from Boschniakia rossica

Yin, Zong-Zhu,Kim, Hang-Sub,Kim, Young-Ho,Lee, Jung-Joon The Pharmaceutical Society of Korea 1999 Archives of Pharmacal Research Vol.22 No.1

Four iridoid compounds were isolated from methanol extract of Boschniakia rossica by repeated column chromatography. Their structures were determined as boschnaloside (1), boschnarol (2), bosnarol methylether (3), and 7-deoxy 8-epiloganic acid (4), respectively. Compound 2, 3, and 4 were isolated for the first time form this plant.

Copolymerization of Ethylene and Norbornene via Polymethylene Bridged Dinuclear Constrained Geometry Catalysts

Yin Bang Zhu,Eun Gyeong Jeong,Bae Wook Lee,Bong Shik Kim,Seok Kyun Noh,Won Seok Lyoo,Dong Ho Lee,Yong Man Kim 한국고분자학회 2007 Macromolecular Research Vol.15 No.5

Triterpenoid saponins from Clinopodium chinense (Benth.) O. Kuntze and their biological activity

Yin-Di Zhu,Jing-Yi Hong,Feng-Da Bao,Na Xing,Ling-Tian Wang,Zhong-Hao Sun,Yun Luo,Hai Jiang,Xudong Xu,Nai-Liang Zhu,Hai-Feng Wu,Gui-Bo Sun,Jun-Shan Yang 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.12

Four new ursane-type triterpenoid saponins, clinopoursaponins A–D (1–4), six new oleanane-type triterpenoid saponins, clinopodiside VII–XII (5–10), as well as eight known triterpene analogues (11–18), were isolated from the aerial parts of Clinopodium chinense (Benth.) O. Kuntze. The structures of the new compounds were determined based on extensive spectral analyses, including 1D (1H and 13C) and 2D NMR experiments (COSY, NOESY, HSQC, 2D TOCSY, HSQC-TOCSY and HMBC), HR-ESI-MS and chemical methods. Compounds 1–18 were evaluated for their protective effects against anoxia/reoxygenation-induced apoptosis in H9c2 cells and cytotoxicities against murine mammary carcinoma cell line 4T1. Compounds 8, 9 and 18 exhibited significant protective effects, while compound 1 exhibited cytotoxic activity with IC50 value of 7.4 μm compared to 7.6 μm for the positive control 10-hydroxycamptothecin.

Overexpression and Characterization of appA Phytase Expressed by Recombinant Baculovirus-Infected Silkworm

( Yin Chen ),( Zhong Ze Zhu ),( Xu Ai Lin ),( Yong Zhu Yi ),( Zhi Fang Zhang ),( Gui Fang Shen ) 한국미생물생명공학회 2005 Journal of microbiology and biotechnology Vol.15 No.3

Iridoid Compounds from Boschniakia rossica

Yin, Zong Zhu,Kim, Hang Sub,Kim, Young Ho,Lee, Jung Joon 충남대학교 약학대학 의약품개발연구소 1999 藥學論文集 Vol.15 No.-

Four iridoid compounds were isolated from methanol extract of Boschniakia rossica by repeated column chromatography. Their structures were determined as boschnaloside (1), boschnarol (2), bosnarol methylether (3), and 7-deoxy 8-epiloganic acid (4), respectively. Compound 2, 3, and 4 were isolated for the first time from this plant.

N6-Methyladenosine modification (m6 A) of circRNA-ZNF638 contributes to the induced activation of SHF stem cells through miR-361-5p/Wnt5a axis in cashmere goats

Yin Ronghuan,Yin Ronglan,Bai Man,Fan Yixing,Wang Zeying,Zhu Yubo,Zhang Qi,Hui Taiyu,Shen Jincheng,Feng Siyu,Bai Wenlin 아세아·태평양축산학회 2023 Animal Bioscience Vol.36 No.4

Objective: The objective of this study was to investigate the effects of N6-Methyladenosine modification-circRNA-zinc finger protein 638 (m6A-circRNA-ZNF638) on the induced activation of secondary hair follicle (SHF) stem cells with its potential mechanisms in cashmere goats. Methods: The m6A modification of ZNF638 was analyzed using methylation immunoprecipitation with real-time quantitative polymerase chain reaction technique in SHF stem cells. The effects of circRNA-ZNF638 on the induced activation of SHF stem cells in m6A dependence were evaluated through the overexpression of circRNA-ZNF638/its m6Adeficient mutants in circRNA-ZNF638 knockdown SHF stem cells. The competitive binding of miR-361-5p to circRNA-ZNF638/Wnt5a 3′- untranslated region was analyzed through Dual-luciferase reporter assay. Results: The m6A-circRNA-ZNF638 had significantly higher transcription at anagen SHF bulge of cashmere goats compared with that at telogen, as well as it positively regulated the induced activation of SHF-stem cells in cashmere goats. Mechanismly, m6A-circRNA-ZNF638 sponged miR-361-5p to heighten the transcriptional expression of Wnt5a gene in SHFstem cells. We further demonstrated that the internal m6A modification within circRNAZNF638 is required for mediating the miR-361-5p/Wnt5a pathway to regulate the induced activation of SHF stem cells through an introducing of m6A-deficient mutant of circRNAZNF638. Conclusion: The circRNA-ZNF638 contributes the proper induced activation of SHF-stem cells in cashmere goats in m6A-dependent manner through miR-361-5p/Wnt5a axis.

An improved horizontally reversible plow design based on virtual assembly semantics and constraint

Lin Zhu,Shuang-Shuang Peng,Yin-Yin Qi,Xi Cheng,Wen-Feng Zhang,Liang-Yuan Xu,De-Quan Zhu 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.1

There exit model errors in the constructed Horizontally reversible plough (HRP) structure through Interference check technique (ICT). This is basically due to missing parts and geometric interference and, hence, has significantly adverse effects in improving HRP. In thispaper an improved design to refine the three dimensional (3D) model of HRP is implemented by using Virtual assembly technology(VAT). To achieve this, the authors propose a combined virtual assembly semantics and constraint for assembly planning and simulationof HRP in the commercial software, e.g., SolidWorks. First, the assembly planning of HRP was captured with a semantics-based model,including spatial position, assembly orientation, type and parameters of the semantic entities; secondly, the assembly simulation of HRPwas performed by using constraint-based VAT, e.g. component grasping, moving and releasing; finally, the obtained HRP model wasverified through ICT again. The results demonstrate that not any model error exists in the refined 3D HRP model any longer and thatsemantics and constrain based VAT can support the interactive operation more effectively and accurately than those with geometric constraints. This technique was previously used for HRP model. Based on the refined 3D HRP model, the design improvement of Remotecylinder base (RCB), an important component of HRP, will be forthcoming in a future paper.

한국 무역 B2B e-Marketplace의 활성화 연구

석은주(Yin-Zhu Shi),김승철(Seung-Chul Kim) 중앙대학교 한국전자무역연구소 2010 전자무역연구 Vol.8 No.4

최근 들어 인터넷 가상공간에서 수출업자와 수입업자를 연결하여 주는 온․오프라인 무역기업들이 활성화되고 있다. 이러한 e-Marketplace는 국제전자거래를 활성화하는 주요 수단으로 자리매김하고 있다. e-Marketplace는 높은 효율성과 낮은 비용으로 무역업자들의 글로벌 마케팅과 거래 속도를 높여주는 역할을 하고 있다. 따라서 본 연구에서는 한국의 무역 B2B e-Marketplace의 활성화 대안을 제시하는데 있다. 이를 위해 본 연구에서는 가장 성공적인 B2B e-Marketplace인 알리바바닷컴의 성공사례를 분석함으로써 한국 무역 B2B e-Marketplace의 활성화 방안을 제시하고자 한다. 알리바바닷컴의 사례를 분석해 본 결과, 성공 요인은 비즈니스 모델의 개발, 전자 지불 시스템, 신용보증의 지원시스템, 중소기업을 위한 직/간접적 대출 혹은 금융 등으로 나타났다. Recently, all of on-off line enterprises actively have promoted in the e-commerce, connecting buyers and sellers in e-marketplace where is a virtual space. This kind of e-marketplace is an effective way that services for worldwide and appears in international electronic transactions. e-marketplace will assist trader's global marketing and trading speeds with high efficiency and low cost. Therefore, this study aims to investigate the activation alternative of Korean B2B e-marketplace to efficiently diffuse e-trade system in Korea. In this study, through case study of the most successful B2B e-marketplace Alibaba.com in B2B e-commerce, the activation alternatives of Korean B2B e-marketplace were presented. As the result of the case analysis of Alibaba.com, the success factors are revealed as followings ; the development of biz model, electronic payment system, the supporting system for credit assure, direct or indirect supporting of loan or finance in medium and small size companies.

한국과 중국 대학생의 부모-자녀 의사소통과 대인관계 능력의 관계 비교

김은주 ( Yin Zhu Jin ) 충남대학교 교육연구소 2013 교육연구논총 Vol.34 No.1

본 연구는 한국과 중국 대학생의 부모-자녀 의사소통과 대인관계 능력이 차이가 있는지 알아보고, 부모-자녀 의사소통과 대인관계 능력이 어떤 관계인가를 탐색하며, 이러한 부모-자녀 의사소통과 대인관계 능력의 관계가 국적에 따라 달라지는지를 알아보기 위하여 진행되었다. 연구문제를 해결하기 위하여 한국 대학생과 중국 대학생 두 집단을 연구대상으로 선택하였다. 한국 대학생은 전라북도에 소재한 3개 대학과 전라남도에 소재한 1개 대학의 학생들을 선정하였고, 중국 대학생은 山東省靑島市에 소재한 1개 대학의 학생들을 선정하였다. 연구대상의 부모-자녀 의사소통과 대인관계 능력을 측정하기 위하여 PACI, ICQ 척도를 사용하였고, 한중 두 집단에 각기 한국어판과 중국어판 설문지를 실시하였으며, 총 580명(한국 309명, 중국 271명)의 자료가 분석에 사용되었다. 주요결과로는 부모-자녀 의사소통 하위영역 중 어머니 개방형, 어머니 폐쇄형에서 한국과 중국 대학생들이 통계적으로 유의한 차이를 보였다. 대인관계 능력의 하위영역 중 처음 관계 맺기, 자기노출, 정서적 지지, 대인갈등 다루기에서 한국과 중국 대학생들이 통계적으로 유의한 차이를 보였다. 그리고 부모-자녀 의사소통과 대인관계 능력의 관계를 알아본 결과 아버지 개방형은 처음 관계 맺기, 자기노출, 정서적 지지, 대인갈등 다루기와 정적 관계를 보였고, 어머니 개방형은 정서적 지지와 정적 관계를 보였다. 그리고 이러한 관계가 국적에 따라 달라지는지 알아본 결과 국적은 아버지 개방형과 처음 관계 맺기, 자기노출의 관계에 대하여 조절작용을 하는 것으로 나타났다. This study was conducted to identify the following things: whether there is any difference between South Korean and Chinese college student`s Parent adolescent communication and interpersonal relationship ability; how they are related; how the relationship becomes different according to the nationality. Korean college students and Chinese college students were selected as the study subjects to resolve the study subject. Korean students were from three colleges in Jellabuk-do and one college in Jellanam-do. And Chinese students were from one college in Cheongdosi, Sandongseong (山東省靑島市). In order to measure the subject`s parent-child communication, and interpersonal relationship ability, PACI, ICQ were used. 580 data (Korean 309, Chinese 271) were used for analysis. The results were as follows. when the national differences in parent-child communication were analyzed, there were meaningful differences between the mother-open communication and the mother-problematic communication. when the national differences in interpersonal relationship ability were analyzed, there were meaningful differences between the approachability, Self-exposure, emotional support, and interpersonal conflict dealing ability. Also, father-open communication revealed positive effects on approachability, Self-exposure, emotional support, and interpersonal conflict according to the result from the analysis between Parent adolescent communication and interpersonal relationship ability. mother-open communication revealed positive effects on emotional support according to the result from the analysis between Parent adolescent communication and interpersonal relationship ability. In addition, when the relationships were checked about the variability according to the nationality, it showed that the nationality played as an adjustment role in the relationship between father-open communication and approachability, Self-exposure.