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Evaluation of mercury exposure level, clinical diagnosis and treatment for mercury intoxication
Byeong-Jin Ye,Byoung-Gwon Kim,Man-Joong Jeon,Se-Yeong Kim,Hawn-Cheol Kim,Tae-Won Jang,Hong-Jae Chae,Won-Jun Choi,Mi-Na Ha,Young-Seoub Hong 대한직업환경의학회 2016 대한직업환경의학회지 Vol.28 No.-
Mercury occurs in various chemical forms, and it is different to health effects according to chemical forms. In consideration of the point, the evaluation of the mercury exposure to human distinguished from occupational and environmental exposure. With strict to manage occupational exposure in factory, it is declined mercury intoxication cases by metallic and inorganic mercury inhalation to occupational exposure. It is increasing to importance in environmental exposure and public health. The focus on the health impact of exposure to mercury is more on chronic, low or moderate grade exposure—albeit a topic of great controversy—, not high concentration exposure by methylmercury, which caused Minamata disease. Recently, the issue of mercury toxicity according to the mercury exposure level, health effects as well as the determination of what mercury levels affect health are in the spotlight and under active discussion. Evaluating the health effects and Biomarker of mercury exposure and establishing diagnosis and treatment standards are very difficult. It can implement that evaluating mercury exposure level for diagnosis by a provocation test uses chelating agent and conducting to appropriate therapy according to the result. but, indications for the therapy of chelating agents with mercury exposure have not yet been fully established. The therapy to symptomatic patients with mercury poisoning is chelating agents, combination therapy with chelating agents, plasma exchange, hemodialysis, plasmapheresis. But the further evaluations are necessary for the effects and side effects with each therapy.
Association of cadmium with diabetes in middle-aged residents of abandoned metal mines
Hee-seung Son,Soo-geun Kim,Byung-seong Suh,Dong-uk Park,Dae-seon Kim,Seung-do Yu,Yeong-seoub Hong,Jung-duck Park,Byung-kook Lee,Jai-dongMoon,Joon Sakong 대한직업환경의학회 2015 대한직업환경의학회지 Vol.27 No.-
Objective: The aim of this study was to determine the association between urinary cadmium (U-cd) concentration and diabetes in middle-aged Korean residents of abandoned mines using the first Health Effect Surveillance for Residents in Abandoned Metal mines (HESRAM). Methods: This study was cross-sectional study conducted on 719 residents between 40?70 years in 38 abandoned metal mines in Korea. Data was collected by HESRAM from 2008 to 2011. The correlation coefficient of U-cd and fasting blood glucose, odds ratio in urinary cadmium tertiles and diabetes prevalence was analyzed according to the sex category. Results: The correlation coefficient U-cd concentration and fasting blood glucose was 0.182 in male. Logistic regression analysis in male revealed a third tertile odds ratio of U-cd (2 μg/g creatinine < U-cd) while diabetes prevalence was 1.81 (95 % CI 1.05-3.12) with adjusted age, BMI, smoking and alcohol consumption, region, family income. On the other hand, the odds ratio for third tertile of U-cd (3 μg/g creatinine < U-cd) between diabetes prevalence in female was 1.39 (95 % CI 0.52-3.72) in addition to adjusted menopausal status. Conclusions: Environmental exposure to cadmium in abandoned mine residents was associated with diabetes in male. Closed monitoring and periodic evaluation of the health effects of chronic environmental exposure on abandoned mines residents will be needed.
Evaluation and management of lead exposure
Hwan-Cheol Kim,Tae-Won Jang,Hong-Jae Chae,Won-Jun Choi,Mi-Na Ha,Byeong-Jin Ye,Byoung-Gwon Kim,Man-Joong Jeon,Se-Yeong Kim,Young-Seoub Hong 대한직업환경의학회 2015 대한직업환경의학회지 Vol.27 No.-
Lead, which is widely used in industry, is a common element found in low concentrations in the Earth’s crust. Implementations to reduce environmental lead concentrations have resulted in a considerable reduction of lead levels in the environment (air) and a sustained reduction in the blood lead levels of the average citizen. However, people are still being exposed to lead through a variety of routes in everyday commodities. Lead causes health problems such as toxicity of the liver, kidneys, hematopoietic system, and nervous system. Having a carcinogenic risk as well, the IARC classifies inorganic lead compounds as probably carcinogenic to humans (Group 2A). Occupational lead poisonings have decreased due to the efforts to reduce the lead concentrations in the working environment. In contrast, health hazards associated with long-term environmental exposure to low concentrations of lead have been reported steadily. In particular, chronic exposure to low concentrations of lead has been reported to induce cognitive behavioral disturbances in children. It is almost impossible to remove lead completely from the human body, and it is not easy to treat health hazards due to lead exposure. Therefore, reduction and prevention of lead exposure are very important. We reviewed the toxicity and health hazards, monitoring and evaluation, and management of lead exposure.
Blood levels of cadmium and lead in residents near abandoned metal mine areas in Korea
Park, Dong-UK,Kim, Dae-Seon,Yu, Seung-Do,Lee, Kyeong-Min,Ryu, Seung-Hun,Kim, Soo-Geun,Yang, Won-Ho,Park, Doo-Yong.,Hong, Yeong-Seoub,Park, Jung-Duck,Lee, Byung-Kook,Moon, Jai-Dong,Sakong, Joon,Ahn, Se Springer-Verlag 2014 Environmental monitoring and assessment Vol.186 No.8