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      • KCI등재후보

        Correlations Between Fasciology and Yin Yang Doctrine

        Hui Tao,Mei-chun Yu,Hui-ying Yang,Rong-mei Qu,Chun Yang,Xin Zhou,Yu Bai,Jing-peng Wu,Jun Wang,Ou Sha,Lin Yuan 사단법인약침학회 2011 Journal of Acupuncture & Meridian Studies Vol.4 No.2

        The aim of this study is to explore the correlations between fasciology and yin yang doctrine. Professor Yuan developed fasciology by three-dimensional reconstruction of connective tissue (fascia) in the trunk and limbs of the human body and tracing back to tissue origins in light of biological evolution and developmental biology. Fasciology states that the human body can be divided into two systems: the supporting-storing system and the functional system. This article elaborates on the roles of the two systems and their mutual relationship. The two systems are used to analyze the yin,the yang, and their relationship. The two systems are promoted but also restricted in different contexts. The supporting-storing system is formed by undifferentiated connective tissue and provides undifferentiated cells and nutrients for differentiated cells of the functional system. Thus, the supporting-storing system could be classified as quiet, similar to yin. The functional system continuously maintains the various functional activities of the human body. Thus, the functional system could be classified as active, similar to yang. In interpreting the yin yang doctrine from the point of view of fasciology, yin can be compared with the supporting-storing system and yang can be compared with the functional system.

      • KCI등재

        HCV-Specific Interleukin-21+CD4+ T Cells Responses Associated with Viral Control through the Modulation of HCV-Specific CD8+ T Cells Function in Chronic Hepatitis C Patients

        Guo-Hua Feng,Fu-Sheng Wang,Ji-Yuan Zhang,Qing-Lei Zeng,Lei Jin,Junliang Fu,Bin Yang,Ying Sun,Tianjun Jiang,Xiangsheng Xu,Zheng Zhang,Jinhong Yuan,Liyuan Wu 한국분자세포생물학회 2013 Molecules and cells Vol.36 No.4

        Interleukin-21 (IL-21)+CD4+ T cells are involved in the immune response against hepatitis B virus (HBV) by secreting IL-21. However, the role of IL-21+CD4+ T cells in the immune response against chronic hepatitis C (CHC) virus infection is poorly understood. This study aimed to investigate the role of IL-21+CD4+ T cells in CHC patients and the potential mechanisms. The study subjects in-cluded nineteen CHC patients who were grouped by viral load (low, < 106 RNA copies/ml, n = 8; high, > 106 RNA copies/ml, n = 11). The peripheral frequency of HCV-specific IL-21+CD4+ T cells was higher in the low viral load group and was negatively correlated with the serum HCV RNA viral load in all CHC patients. Meanwhile, IL-21+ cells accumulated in the liver in the low viral load group. In vitro, IL-21 treatment increased the expression of proliferation markers and cytolytic molecules on HCV-specific CD8+ T cells. In summary, these findings suggest that HCV-specific IL-21+CD4+ T cells might contribute to HCV control by rescuing HCV-specific CD8+ T cells in CHC patients.

      • KCI등재

        Registry-based stroke research in Taiwan: past and future

        Cheng-Yang Hsieh,Darren Philbert Wu3,,Sheng-Feng Sung 한국역학회 2018 Epidemiology and Health Vol.40 No.-

        Stroke registries are observational databases focusing on the clinical information and outcomes of stroke patients. They play an important role in the cycle of quality improvement. Registry data are collected from real-world experiences of stroke care and are suitable for measuring quality of care. By exposing inadequacies in performance measures of stroke care, research from stroke registries has changed how we manage stroke patients in Taiwan. With the success of various quality improvement campaigns, mortality from stroke and recurrence of stroke have decreased in the past decade. After the implementation of a nationwide stroke registry, researchers have been creatively expanding how they use and collect registry data for research. Through the use of the nationwide stroke registry as a common data model, researchers from many hospitals have built their own stroke registries with extended data elements to meet the needs of research. In collaboration with information technology professionals, stroke registry systems have changed from web-based, manual submission systems to automated fill-in systems in some hospitals. Furthermore, record linkage between stroke registries and administrative claims databases or other existing databases has widened the utility of registry data in research. Using stroke registry data as the reference standard, researchers have validated several algorithms for ascertaining the diagnosis of stroke and its risk factors from claims data, and have also developed a claims-based index to estimate stroke severity. By making better use of registry data, we believe that we will provide better care to patients with stroke.

      • KCI등재

        Preparation of Monascus-fermented ginkgo seeds: optimization of fermentation parameters and evaluation of bioactivity

        Wu Zhihao,Miao Wen,Yang Yuhan,Fan Gongjian,Wu Caie,Li Tingting,Xie Chunyan,Shen Dongbei 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.6

        In this study, a high monacolin K yield was achieved through solid-state fermentation of Ginkgo biloba seeds. Monascus purpureus suspension made from red yeast rice was used as spore inoculum. Fermentation conditions in solid-state fermentation were optimized using response surface methodology, and the optimal conditions for the maximum monacolin K yield (17.71 ± 1.57 mg/g) were 0.22% ammonium sulfate, 0.34% ammonium chloride, 0.05% magnesium sulfate, fermentation time of 12 days, inoculation volume of 11%, and temperature of 27 °C. The total phenolic content of Monascus-fermented ginkgo seeds attained 9.67 mg GAE/g, 4.88-fold higher than that of unfermented ginkgo seeds. The scavenging abilities of DPPH and ABTS free radicals increased to 9.79 mg TE/g and 13.92 mg TE/g, respectively. These findings highlight the importance of investigating the optimal fermentation conditions for maximum monacolin K yield and the utilization value of ginkgo seed as fermentation substrate for higher bioactivities.

      • KCI등재

        Dynamic control stability analysis of pipeline intelligent plugging robot in its deceleration and precise positioning

        Yang Tang,Jie Wu,Xiang Liu,Xin Yang,Yuan Wang,Haoyu Xiong 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.9

        In order to realize the precise positioning of the tools in the pipeline repair operation, solve the problems of the traditional throttle speed control, such as slow response, long deceleration distance and so on, this paper explores a deceleration process of a pipeline intelligent plugging robot (PIPR) that relies on the friction between slips and the pipe, and establishes its dynamic model based on fuzzy PID force servo control. The influence of PIPR initial velocity, expected deceleration distance, accumulator setting on the response time, positioning accuracy, overshoot and stability during deceleration is analyzed, and the results show that: as the initial velocity increases, the time for slips to contact the pipe decreases, the overshoot of the centroid acceleration gradually increases, the maximum overshoot is -3.4 m/s 2 , the control time of the deceleration process is within 30 s, the positioning accuracy is within 5 %; the expected deceleration distance has a greater impact on the positioning accuracy of the system than the initial velocity; and the accumulator setting has little effect on the positioning accuracy and stability of the system. These studies provide guidance for the design of pipeline robot speed control and positioning system.

      • KCI등재

        Nuclide assignment for an isolated band observed in the 10B + 114Cd reaction

        Yang Qing-Yu,Song Li-Na,Ma Ying-Jun,Yang Dong,Ma Ke-Yan,Wu Xiao-Guang,Zheng Yun,Li Cong-Bo 한국물리학회 2021 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.79 No.3

        Three experiments based on the nuclear reactions 14N + 110Pd, 10B + 114Cd and 11B + 114Cd were performed. Coincidences between γ-rays emitted from these reactions were measured with the same detection array which consisted of 14 HPGe detectors. A new band structure was identified using an offline analysis of coincidence data. Because of the isomeric nature of the bandhead, the new band cannot be connected to any known state in any residual nuclei of the used reactions. To assign it to a specific nucleus, we evaluated the experimental population intensities of various known bands in known residual nuclei and investigated the entrance channel effects in the three different experiments. The population intensity patterns of the known bands were observed to exhibit regular systematics. Based on such experimental systematics, we suggest that the most reasonable nuclide assignment for the new band is the 120I nucleus.

      • SCIESCOPUS

        Numerical study on bearing behavior of pile considering sand particle crushing

        Wu, Yang,Yamamoto, Haruyuki,Yao, Yangping Techno-Press 2013 Geomechanics & engineering Vol.5 No.3

        The bearing mechanism of pile during installation and loading process which controls the deformation and distribution of strain and stress in the soil surrounding pile tip is complex and full of much uncertainty. It is pointed out that particle crushing occurs in significant stress concentrated region such as the area surrounding pile tip. The solution to this problem requires the understanding and modeling of the mechanical behavior of granular soil under high pressures. This study aims to investigate the sand behavior around pile tip considering the characteristics of sand crushing. The numerical analysis of model pile loading test under different surcharge pressure with constitutive model for sand crushing is presented. This constitutive model is capable of predicting the dilatancy of soil from negative to positive under low confining pressure and only negative dilatancy under high confining pressure. The predicted relationships between the normalized bearing stress and normalized displacement are agreeable with the experimental results during the entire loading process. It is estimated from numerical results that the vertical stress beneath pile tip is up to 20 MPa which is large enough to cause sand to be crushed. The predicted distribution area of volumetric strain represents that the distributed area shaped wedge for volumetric contraction is beneath pile tip and distributed area for volumetric expansion is near the pile shaft. It is demonstrated that the finite element formulation incorporating a constitutive model for sand with crushing is capable of producing reasonable results for the pile loading problem.

      • KCI등재

        한국어와 중국어의 한자어 형태소 분포 대조 연구

        WU YANG,윤나영 국제어문학회 2022 국제어문 Vol.- No.95

        이 글은 한국어 한자 형태소와 중국어 어소의 분포 체계와 양상을 대조하는 것을 목적으로 한다. 이를 위해 김창섭(2013)에서 제시한 한자어의 ‘2자어 3자어 문법’과 Yuen Ren Chao(1968)에서 제시한 중국어 어소 분포 체계를 바탕으로 형태소 분포 대조 틀을 마련하고, 한국어 말뭉치에서 고빈도로 출현하는 한자 형태소 100개를 대상으로 실제 분포 양상을 관찰하였다. 이후 한국어와 중국어에서 한자 형태소의 분포 위치별 대조와 분포 부류별 대조를 통해 공통점과 차이점을 밝혔다. 본 연구의 결과는 한자 문화권의 한국어 학습자를 위한 한국어 교육에 있어서 한자어의 분석 및 형성 교육을 위한 기초 연구 자료로서 활용될 수 있다.

      • Association of Oral Contraceptives Use and Lung Cancer Risk among Women: an Updated Meta-analysis Based on Cohort and Case-control Studies

        Wu, Wei,Yin, Zhi-Hua,Guan, Peng,Ren, Yang-Wu,Zhou, Bao-Sen Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3

        Background: Previous studies on the association of oral contraceptives (OC) use and lung cancer generated inconsistent findings. The aim of this study was to confirm any definite correlation between OC use and lung cancer risk. Methods: Publications were reviewed and obtained through PubMed and EMBASE databases literature search up to November, 2013. Reference lists from retrieved articles were also reviewed. The language of publication was restricted to English. A meta-analysis was performed to evaluate the association by calculating pooled odds ratios (ORs) and 95% confidence intervals (CIs). Results: A total of 14 studies consisting of 9 case-control studies and 5 cohort studies were finally included in this meta-analysis. There was no significant association observed between OC use and lung cancer risk in the overall analysis (OR=0.91; 95% CI=0.81-1.03). There was a significant protective effect in Europe (OR=0.74; 95% CI=0.60-0.91) and a borderline significant protective effect with an adenocarcinoma histology (OR=0.90; 95% CI=0.80-1.01) in subgroup analyses. No association was observed for methodological quality of study, study design, smoking status and case number of study. Conclusion: This meta-analysis suggests that OC use is not likely to be associated with the risk of lung cancer at all. While a significant protective effect of OC use on lung cancer was observed in Europe, interpretation should be cautious because of the potential biases of low-quality studies. At the same time, more attention should be paid to the possible association of OC use with adenocarcinoma of lung. Our findings require further research, with well-conducted and large-scale epidemiological studies to confirm effects of OC use on lung cancer.

      • KCI등재

        A novel stricture prevention technique in blunt urethral injury: A multi-center retrospective observational study

        Yang Mi,Jingyu Wang,Jinfeng Wu,Xiaopeng Wang,Bin Yang,Ruimin Ren,Yangang Zhang,Xiaobin Yuan,Xuhui Zhang 대한비뇨의학회 2022 Investigative and Clinical Urology Vol.63 No.1

        Purpose: Bulbar injury is the most common type of urethral injury. This study investigated the efficacy and safety of a novel technique, local urethral flushing, in preventing stricture formation after blunt bulbar urethra injuries. Materials and Methods: This retrospective study included 205 males diagnosed with straddle injury-induced bulbar urethra injury at the Shanxi Bethune Hospital and First Hospital of Shanxi Medical University between January 2015 and January 2019. Patients were diagnosed by retrograde urethrography and classified as partial or complete urethral rupture according to the urethral integrity after injury. Complete urethral rupture patients received suprapubic cystostomy and received urethroplasty 3 months later. Patients with partial urethral rupture underwent endoscopic urethral realignment by cystoscopic guide-wire guided catheterization. Patients with both injury types were divided into 3 groups. The treatment groups received urethral flushing with 0.05% dexamethasone through a secondary ureteral catheter that locked at the urethral lesion. The blank control groups received normal saline. The negative control groups had only a single ureteral catheter placed. Patients were assessed for pain during catheterization, infection, and stenosis, and followed for at least 2 years. Results: Stenosis rates and length were significantly reduced in the normal saline groups, and even further reduced in the dexamethasone groups. The negative control groups had significantly higher infection rates than patients in the dexamethasone or saline groups. Conclusions: Local urethral flushing with dexamethasone could significantly decrease urethral stenosis rates and severity without increasing patients’ discomfort or infection risk.

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