고호모시스테인증과 동반된 소뇌출혈 1예

홍석찬,안재영,조수진,정진상,이광호,홍승철,변홍식 대한신경과학회 1999 대한신경과학회지 Vol.17 No.3

개 원발성 면역매개성 혈소판 감소증 증례

유찬,임수정,이선희,박형진,김태신,송은식,김덕환,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2009 動物醫科學硏究誌 Vol.16 No.1

A 13-year-old, castrated male, Maltese-dog was admitted to the Veterinary Medical Teaching Hospital of Chungnam National University with the history fo petechiae. On physical examination, she had petechiae and ecchymoses at her back, bilateral inguinal region, and inner part of ear pinna. CBC indicated neutrophilia and severe thrombocytopenia. A few platelets, no autoagglutination of RBC, and no spherocyte were observed. Coagulation profile demonstrated normal PT, and aPTT. No significant findings was not found on serum biochemical profile and electolytes test. FNA of a splenic mass which was found on the abdominal radiograph and sonograph demonstrated extramedullary hematopoiesis, Proteinuria was observed on urinarysis. Primary immune-mediated thrombocytopenia was diagnosed by ruling out of other underlying disease, severe thrombocytopenia, and response to immunosuppressive therapy. Prednisone and antibiotics were administered orally and parenterally, respectively. After altering prednisone to azathioprine, the number of platelets was recovered to normal range and petechiae and ecchymoses were improved.

만성신부전 환자에서 Recombinant Human Erythropoietin(rhEPO)의 피하주사시 생체이용율

김경수,이경훈,이영수,김광호,김용식,신상구,박찬웅 大韓臨床藥理學會 1993 臨床藥理學會誌 Vol.1 No.1

한국형 후각검사 KVSS Test의 개발

홍석찬,유영석,김은서,김석천,박수홍,김진국,강성호 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

靑綠色 燐酸바륨顔科의 製造와 物性

金燦國,薛秀德 동아대학교 공과대학 부설 한국자원개발연구소 1979 硏究報告 Vol.4 No.1

Ba(CH)₂·8H₂O, (NH₄)₂HPO₄ 및 MnO₂간의 混合比를 任意로 變化시킨 試料를 電氣爐에 넣고 하燒溫度를 變化시켜 Ba₃(PO₄)₂를 製造하는 實驗이다. 混合比 3:1:2:1.2의 試料를 800℃에서 3時間 가량 하燒시켜 본 結果, 90% 以上의 收得率을 가진 靑綠色의 α-Ba₃(PO₄)₂가 生成되었다. A study on the formation of Ba₃(PO₄)₂ was carried in different sample that change mole ratio of Ba(OH)₂·8H₂O, (N₄)₂HPO₄, MnO₂ and changed their calcined temperature in an electric muffle furnace. When sample thus mixed mole ratio 3.1.2.1.2 was calcined at a temperature range 800℃ for 3 hours, 90% and over calcined material was recovered in the form of α-Ba₃(PO₄)₂ with a greenish blue colour.

도시특성을 고려한 교통유발계수 산정에 관한 연구 : 대전시를 중심으로 In the City of Daejeon

김명수,전찬용,황현종 한밭대학교 2004 한밭대학교 논문집 Vol.21 No.-

The biggest problem in urban transport is congestion. The purpose of this study is to understand "Electronic Road Pricing System, which is one of the traffic demand control plan for relieving such a traffic congestion, and look for the plans to improve it. For this, traffic inducement coefficient was selected, which shows the regional characteristic of Daejeon through investigation on each facility. As one can see from the investigated inducement coefficient, the same type of facilities show different characteristics. Also, it is thought that per unit burden charge that has been maintained for over 20 years should be raised relevantly in consideration to inflation. Also, it is thought that several ways have to be sought for the facility owners' active participation in the traffic volume reduction program. Studies like this research would bring the following items as their effect; Relieve traffic congestion(partly) and reduce the passage time. Personal benefits following fuel cost etc. Socio-economic effect following logistics cost and environmental pollutants etc.

대기와 해수의 온도변화 및 주기분석

류찬수 조선대학교 기초과학연구소 1990 自然科學硏究 Vol.13 No.1

This paper is to analyse the period and variation of the temperature of the atmosphere and sea water with respect to seven observation stations selected on the southern, eastern and western coasts of Korea. The results are as follows; Sea water temperature changed more slowly then atmosphere temperature, and it is smaller in relation to the amplitude(A). It shows that the correlationship was very strong because the correlation coefficient between atmosphere and sea water temperature appeared very close to (A). The regression equation of atmosphere and sea water temperature can be expressed as Ti=a_1+a_1cos Di+b_1sin Di. The time gap that shows the minimum temperature of atmosphere and sea water was much longer than that of their maximum temperatures, and it was the longest at the northern observation stations. The minimum temperature of sea water occurred earlier than that of atmosphere in Kunsan. The amplitude of sea water temperature on the eastern coast was much smaller than that on western and southern coasts. The maximum temperature of sea water in Wolmido was higher than that of atmosphere, and the minimum temperature of atmosphere in Kunsan was higher than that of sea water. To interprete the particular phenomena above the autocorrelationship according to the oceanity and the continentality was worked out so that the only correlation coefficient between oceanity and minimum temperature of sea water showed 0.93, and that between others was below 0.3. Therefore, it must be interpreted in relation to other factors.

어류에 발생하는 Mycobacterium 속 세균성 질병에 대하여

이덕찬,김도형,박수일 한국어병학회 2001 한국어병학회지 Vol.14 No.3

Mycobacterium 속 균은 일반적으로 Gram 양성 및 음성균의 세포벽에서 관찰되는 구조 및 성분과 차이가 나며, 장시간 동안 배양해야 하는 등의 특성이 있다. Mycobacterium속 세균의 세포벽에는 다량의 mycolic acid가 함유되어 일반 염색법으로느 염색이 잘되지 않으나 일단 염색되면 산이나 알칼리에 탈색되지 않는 성질을 가지고 있으므로 항산성균이다. 그람 양성 간균, 비운동성, 호기성이며 아포는 없고 발육이 느리다. 그러므로 이러한 균의 배양, 분리 그리고 동정에는 Gram 양성 및 음성균에서 수행하는 일반적인 생화학 및 생리학적 방법 외의 다양한 시험들이 필요하다. Atexander(1913)에 의하여 'piscine tuberculosis'로 보고된 후 어류에 피해를 주는 여러 종류의 Mycobacterium 속의 세균군이 보고되었다. 최근까지 해수어와 담수어 40과 151종 이상의 어류에서 감영 가능성이 보고되어 있으며 특히, 열대성 담수어와 해수어, 온대성 담수어류 및 관상어류 등에서 주로 보고되었다. 어류에 감염을 일으키는 균으로는 M. marinum, M. chelonae 및 M. fortuitum이 잘 알려져 있으나, 최근 어류뿐만 아니라 양서류, 파충류 및 갑각류 등에서 M. simiae, M. scrofulaceum, M. poriferae, M. kansasii 및 M. peregrinum 등과 미국의 Chesapeake 만의 자연산 sea bass에서 Mycobacterium chesapeake sp. nov.이 보고되었다. 어류의 mycobacteriosis는 오염된 먹이나 수중 부유물질에 부착된 병원체의 어체 상처 접촉에 의하여 수평적으로 확산될 수 있다. 감염된 어류는 먹이 섭취 불량, 운동성 저하, 복수 저류로 인한 복부팽만 등의 외부증상과 신장, 비장 및 간 등의 육아종 형성 등 전신적, 만성적 그리고 진행성 병변을 보인다. 어류에 질병을 일으키는 Mycobacterium sp는 65kDa과 <14kDa의 분자량을 가진 ECP를 생산하며, 세균 종에 따라 mucinase, lipase 또는 RNase를 생성한다. M. marinum에 의하여 생성된 ECP에 의한 독작용은 Vibrio anguillarum이나 Aeromonas hydrophila ECP에 비하여 약하며, 무지개송어와 나일틸라피아에 대한 LD_50은 400μg fish^-이다. 이들 병원균에 의한 감염증 발생 후 항생제를 사용하면 어류의 폐사는 줄어들지만 완전한 치료는 어려우므로 예방 조치가 필요할 것이다. 그리고 어류에 감염을 일으키는 Mycobacterium sp.에 의한 인체감염이 전세계적으로 보고되 있으며, 국내에서도 환경이나 사람의 객담(喀痰, sputum)으로부터 M. marinum과 M. fortuitum complex가 분리 보고되고 있으므로 앞으로 어류로부터의 감염에 대한 많은 연구가 필요하다. Bacteria of the genus Mycobacterium ard generally rod-shape, gram-positive, nonspore-forming, non-motile and acie-fast. They are quite different from the structures and compounds in common bacteria. The bacteria are not decolorized with acid-alcohol because of the cell walls composed of mush mycolic acis. The bacteria are relatively fastidious, growing very slowly on only a few special media. Therefore many kinds of experimental methods should be needed to isolate and identify mycobacteris besides physiological and biochemical methods commonly used. Serveral bacteria of the genue Mycobacterium have been reported after Alexander(1913)described piscine tuberculosis to refer to fish mycobacteriosis. Probablility of infection from 40 families, 151 species of fich to human hsd been reported until recent year, particularly including tropical freshwater and marine fishes, temperate frashwater fishes and aquarium fishes. The causative agents of the fish mycobacteriosis involve M. marinum, M. chelonae and M. fortuitum. Currently M. simiae. M. scrofulaceum, M. poriferae, M. kansasii and M. peregrinum have aldo been found in amphibians, reptiles and crustaceans and M. cheapeaki sp. nov. was isolated from wild sea bass in the gulf of Chesapeake, the US. The most probable route of transmission for fish mycobacteriosis is oral or through injuries of the skin which can be exacerbated by external parasites. Mycobacteriosis is a chronic progressive disease, with various clinical signs, including lack of movement coordination, abdominal swelling, inappetence, emaciation and inflammation of the skin. Interally greyish white nodules develop on various organs, particularly the liver, kidney and spleen. ECP from virulent Mycobacterium sp. has two different proteins, a 65 kDa and <14 kDa, and the ECP may contain mucinase, lipase or RNase depending on the kinds of bacteria. The ECP of M. marinum, with the LD_50 dose equated to 400㎍ fish^-1 for rainbow trout and Nile tilapia, is more toxie than those of Vibrio anguillarum and Aeromonas hydrophila. Prevention of the disease is perhaps the single most economical means to combat mycobacteriosis, since infected fish cannot be completely cured althouth the mortality may be reduced by application of antibiotics. It may be difficult to ruld out the possibility of human infection by Mycobacterium sp. which is virulent to fish, as the related reports have been described worldwide and also reported domestically on isolation of M. marinuma and M. fortuitum complex from the environment and sputum.

압박 고 나사로 치료한 대퇴골 전자부 골절 : 고정 실패의 인자에 대한 분석 Analysis of Factors associated with Failure of Fixation

유찬훈,김홍태,변영수,남준모,조영호,문성건 대한골절학회 2002 대한골절학회지 Vol.15 No.4

목 적 : 압박 고 나사로 치료한 대퇴골 전자부 골절의 고정 실패에 영향을 미치는 요소에 대하여 분석하고자 하였다. 대상 및 방법 : 1995년 5월부터 2000년 7월까지 대퇴골 전자부 골절을 압박 고 나사를 이용하여 치료하고 1년 이상 추시가 가능했던 97예를 대상으로 하였다. 골절의 분류는 Jensen 분류법을, 골다공증의 정도는 Singh 지수를 이용하였다. 술후 방사선 검사에서 경체각, 정복 상태, 지연 나사의 대퇴골 두 내 위치, tip-apex distance(TAD) 및 지연 나사의 활강 거리를 측정하였고 고정 실패에 미치는 영향을 통계학적으로 분석하였다. 결 과 : 97예 중 17예(17%)에서 고정 실패가 발생하였고 그 중 지연 나사의 과도한 활강으로인한 경우가 15례(15.4%), 골두 천공 1얘, 10도 이상의 외반 변형 1예였다. 고정 실패의 발생과 80세 이상의 고령, 불안정성 골절, telescoping 정복, 원위 골편의 내측 혹은 전방 전위, 대퇴골 두 내 지연 나사의 위치와 밀접한 관계가 있었다. 결 론 : 압박 고 나사를 이용한 대퇴골 전자부 골절의 치료에서 고정 실패를 방지하기 위해서는 정확한 정복이 필요하고 대퇴골 두 내에서 지연 나사의 전방 위치를 피하는 것이 좋을 것으로 사료된다. Purpose : This study was performed to analyze the significant factors that may affect failure of fixation in trochanteric fractures of the femur treated with the compression hip screw. Materials and Methods : From May 1995 to July 2000, the authors analyzed 97 cases of trochanteric fracture of the femur treated with the compression hip screw and followed more than one year. We classified the fracture type by Jensen's method. We used Singh index for the degree of osteroporosis. In the post-operative radiograph, we checked neck-shaft angle, state of reduction, position of the lag screw within the femoral head, tip-apex distance, and sliding distance of the lag screw. The relationship between these factors and failure of fixation was statistically analyzed. Results : There were 17 cases(17.5%) of failure of fixation ; 15 cases(15.4%) of excessive sliding of the lag screw, 1 case (1%) of cutting out of the lag screw, and 1 case (1%) of valgus malunion. There were significant relationship between failure of fixation and old age over 80 , unstable fracture, telescoping reduction, anterior or medial displacement of the distal fragment, and anterior placement of the lag screw within the femoral head. Conclusion : Accurate reduction and avoidance of the placement of the lag screw in the anterior part of the femoral head were important factors to prevent failure of fixation in trochanteric fractures of the femur treated with the compression hip screw.

蘆嶺山脈을 中心으로 한 全南北地方의 氣候要素 分布와 變化特性 및 氣象要素間의 相關관계

柳贊洙,申一秀 조선대학교 기초과학연구소 1987 自然科學硏究 Vol.10 No.1

This paper is a study on the distribution of the climatic elements, characteristics of change and correlation among the meteorological variable in the Chollado area. For this study the MONTHLY WEATHER REPORTS over the last ten year(1971~1980) were u^tilized. Weather station were nine in number, those of Kunsan, Puan, Chonju, Cho^ng-up, Imshil, Namwon, Kwangju, Hampyong and Mokpo. The meteorological variable include relative humidity, evaporation, precipitation, air temperature, etc. As the result of this study, each climatic element showed the same aspects of change. During the summer, relative humidity, evaporation and precipitation, and air temperature reached their highest points, and wind speed, wind direction and diurnal temperature range fell to their lowest points, and the highest point appeared two times. The values of the climatic variables differed greatly among the different observatories. Integrated interpretation is also needed because there is more or less correlation among all the meteorological elements.