극치통계해석을 이용한 Al 2424-T3합금의 피로강도설계에 관한연구

조석주,예규현,주원식 東亞大學校 大學院 1997 大學院論文集 Vol.22 No.-

The fracture of a structure, machine, machine part comes of surface micro-crack initiated and propagated at the root notch, where the actual stress is high. Irregular distribution characteristics of micro-crack on the basis of elastic-plastic fracture mechanics doesn't predict exactly remaining life of them. It is thought that maximum micro-crack length represents the total fatigue damage because fatigue can be characterized as a progressive failure phenomenon that proceeds by the propagation and coalescence of micro-cracks to an unstable size. The maximum micro-crack length in an area larger than the sample area can by estimated by statistics of extremes. Therefore, the remaining life of components can be accurately predicted using the distribution of micro-crack length in critical area and the fatigue model.

蓄血證과 蓄水證의 病理에 關한 文獻的 考察

崔昇勳,安圭錫,文濬典,朴鐘鉉 대한동의병리학회 1994 동의생리병리학회지 Vol.9 No.1

연구배경 : 축혈증과 축수증은 태양표증이 풀리지 않아 邪熱이 안으로 들어가 형성된 양대병증으로 이들의 부위 및 병리에 대한 설명이 명확치 못한 점이 많다. 이에 축혈증과 축수증의 본래 의미를 검토하고 그것의 병리에 대해서 부위, 증상, 개체별 차이 및 측수ㆍ축혈증의 실질에 대해서 연구하고자 함. 연구방법 : 축혈증과 축수증에 관련된 조문 및 유사증에 관한 조문들을 가려서 역대 주가들의 주를 참고로 연구하였다. 축수ㆍ축혈의 실질에 관해서는 처방을 중심으로 사용된 약재들의 현대적 약리작용을 통해 연구하였다. 결과 : 축혈증은 하초소복부의 혈액순환계통의 질환과 관련된 것으로 나타났으며, 축수증은 방광자체의 문제이기 보다는 기화분리로 인한 수액대사 장애와 관련된 병증으로 볼 수 있다. Through the philological study on syndrome of stagnated blood & syndrome of stagnated water, the results are obtained as following; 1. It is resonable to understand that the location of Syndrome of Stagnated Blood(蓄血證) is the lower abdomen and Syndrome of Stagnated Waste (蓄水證) is not exactly the disorder of Gall Bladder itself, but the disturbance of waterbolism derived from the disturbance of Qi (氣) transformation. 2. Syndrome of Stagnated Blood is that, being uncured Taiyang Channel Syndrom (太陽病), pathogen enters inside and pathogenic heat combines with blood at the lower abdomen; its main signs are spasmatic distention or muscular rigidity of the lower abdomen, mental derangement and normal urination. 3. Syndrome of Stagnated Water is that, being uncured Taiyang Channel Syndrom, pathogenic heat enters inside and combines with water and leads to disturbance of waterbolism; its main signs are thirsty, dysphoria, and difficulty in urination. 4. In the view of Western Medicine, Syndrome of Stagnated Blood is related with the disease of the blood circulation-especially in microcirculation- of the lower abdomen; Syndrome of Stagnated Water is similar to the disease which is related with the abnomal state of osmotic density derived from the unblance of electrolytes. 5. Lee Je-Ma regared the Syndrome of Stagnated Blood as SinSooYeolPyoYeolByung(腎受熱表熱病) of ShaoYin-Ren (少陰人), so explained it as the disease derived from the lower abdominal accumulation of Yang-Qi (陽氣) which coudn't have ascended; and regarded the Syndrome of Stagnated Water as PiSooHanPyoHanByung (脾受寒表寒病) of ShaoYang-Ren (少陽人), so explained it as the disease derived from the accumulation of internal heat because of discending disturbance of Yin-Qi (陰氣).

膈下逐瘀湯과 膈下逐瘀湯合四君子湯의 抗癌 및 免疫調節作用에 關한 實驗的 硏究

崔昇勳,安圭錫,文濬典,高光錫 대한동의병리학회 1994 동의생리병리학회지 Vol.9 No.1

연구배경 : 암은 사망의 주요 원인이 되는 질환으로 매년 증가하고 있는 추세이다. 이에 mouse에 암을 유발하여, 약물치료를 시행함으로써 높은 치료효과를 거두는 한약제재를 개발하여 암의 치료에 기여하고 아울러 근본적인 예방치료에 대한 새로운 방법을 제시하고자 함. 방법 : 생쥐에 Sacroma 180을 이식하여 복강암을 유발하고 격하축어탕 및 격하축어탕합사군자탕을 투여하여 생명연장률과 B cell 및 T cell, 혈청항체가, 임파구증식반응, IL-2 생산능 및 자연살해페소의 활성도를 측정하였다. 결과 : 격하축어탕과 격하축어탕합사군자탕은 면역조절작용을 통한 항암효과가 있을 것으로 생각되며, 활혈거어제인 격하축어탕과 보기제인 사군자탕을 합방했을때, 그 효과가 증가되었다. In order to investigate the effects of Gyeokhachukeotang and Gyeokhachukeotang plus Sagunjatang on anti-tumor and immunodulatory reaction to the ICR and C57BL/6 mice which have abdominal tumor after Sarcoma-180 cells were transplanted, the extracts of herbal medicines above mentioned were orally administered to the mice for 21 days to observe the extention of survival duration of the mice, quantitation of T cells and B cells, productivitiy of interleukin-2, lymphocytes transformation, hemagglutinin titer and hemolysin titer and activity of splenic natural killer cells. The results are summarized as follows; 1. In the effect of life extention, the Gyeokhachukeotang-medicated mice group inclined to show extended duration of life, which is of no great significant difference and the mice group medicated with mixture of Gyeokhachukeotang plus Sagunjatang appeared to survive longer than the Gyeokhachukeotang-medicated mice group, which is not meaningful. 2. Considering T cell and B cell content, the Gyeokhachukeotang-medicated mice group had a meaningful increase in B cell (P<0.05) content, and the mice group medicated with the mixture of Gyeokhachukeotang plus Sagunjatang remarkably showed a significant increase in both T cell and B cell (P<0.01). 3. Considering serum antibody titer tended to increase in case of the Gyeokhachukeotang-medicated mice group, which is of no significant difference, while decreasing in case of the mice group medicated with mixture of Gyeokhachukeotang plus Sagunjatang. 4. In lymphocyte transformation marked a significant increase the Gyeokhachukeotang-medicated mice group, marked a significant (P<0.01), and remarkably showed a significant increase the mice group medicated with the mixture of Gyeokhachukeotang plus Sagunjatang (P<0.001). 5. As for the productivity of interleukin-2 and the activity of NK cells, the both tested groups inclined to show an increase or a decrese, but there is no significance.

횡문근 융해증의 Tc-99m Methylene Diphosphonate 신티그라피 소견

한창진,박찬희,윤석남,배문선,김수지,신규설 아주대학교 1997 아주의학 Vol.2 No.2

Many causes of rhabdomyolysis have been reported in the literature. Technetium-99m methylene dipho-sphonate (Tc-99m MDP) bone scintigraphy is considered to be the most sensitive and effective modality in defining the extents of disease involvement and follow-up of patients with rhabdomyolysis. In this paper, we reviewed two cases of generalized rhabdomyolysis related to seizure activities and two cases of localized rhabdomyolysis related to an excessive exercise. In addition other causes of rhabdomyolysis and possible mechanisrns of Tc-99m MDP uptake are discussed briefly.

Feature Selection Algorithm using Random Forest to Diagnose Cancer

Gyoo-Seok Choi,Jong-Jin Park,Ha-Nam Nguyen 한국인터넷방송통신학회 2009 International Journal of Internet, Broadcasting an Vol.1 No.1

A Study on Feature Selection Method based on Random Forest for Cancer Diagnosis System

Gyoo Seok Choi(최규석),Jong jin Park(박종진),Ha-Nam Nguyen 한국정보기술학회 2008 한국정보기술학회논문지 Vol.6 No.3

One of the most important problems in bioinformatics is how to extract the useful information from a huge amount of data, and make a decision in diagnosis, prognosis, and medical treatment applications. Machine learning approaches such as Neural network, Decision tree, Support Vector Machines are well suited for domains characterized by the presence of large amount of data, noisy patterns, and absence of general theory. The main goal of our research is to propose an efficient feature selection method to achieve a cancer diagnosis system with high accuracies, and good adaptability to clinical dataset. We propose a new feature selection method based on Random Forest(RF) to be applicable to the learning algorithm for Cancer Diagnosis System. The experiments on clinical dataset such as colon cancer indicate that our proposed method obtain higher and more stable classification performance than the baseline methods. Our method also results in comparable and better classification performance than other classification methods.

유통업분야에서 사전분쟁해결제도의 도입가능성에 관한 고찰 - 미국 DRB제도를 중심으로 -

염규석 ( Gyoo Seok Yoem ) 한국유통법학회 2014 유통법연구 Vol.1 No.-

Disputes in distribution industry are major obstacles in the development of the industry. Solving conflicts in distribution industry by handling these disputes is of significance. Though resolution system of disputes such as trial, arbitration and mediation exist, handling disputes occuring in complicated trading relation- ships like distribution industry still has some limitations in that it is hard to solve these problems quickly without hurting relationships between the two. So I``d like to discuss Dispute Resolution Board(DRB) which is a system in US as a resolution to this issue in the hope that it can solve current disputes and further prevent disputes in distribution industry from happening.

지능형 주행 안내 시스템을 위한 유전 알고리즘에 근거한 최적 경로 탐색 알고리즘

최규석(Gyoo-Seok Choi),우광방(Kwang-Bang Woo) 제어로봇시스템학회 1997 제어·로봇·시스템학회 논문지 Vol.3 No.2

진화 프로그램에 기초한 기종점간 최적경로탐색 알고리즘의 개발

崔圭錫(Gyoo-Seok Choi),禹廣芳(Kwang-Bang Woo) 대한전기학회 1997 전기학회논문지 Vol.46 No.2

자료흐름분석 모델을 이용한 대상의 식별과 대상중심의 설계규칙에 관한 연구

김규석(Kim. Gyoo Seok),윤창섭(Yoon Chang Sup) 한국정보과학회 1989 한국정보과학회 학술발표논문집 Vol.16 No.2

기능중심적 분할방법론을 대상중심설계에 이용하고 그 결과를 Ada 언어로 구현한 기존의 이론들은 대상중심설계에서 가장 중요한 대상을 식별하기 위해 구체적이고 정형적인 방법을 제시하지 못하고 있다. 따라서 본 논문은 자료흐름분석 모델로부터 정형적인 대상의 식별방법과 이를 이용한 대상중심의 설계규칙을 제시하고, 사례연구를 통하여 타당성과 유효성을 평가하였다.